Navigation Links
Paradigm shift needed to combat drug resistance

Hamilton, ON (Oct. 14, 2009) When people travel, bacteria and other infectious agents travel with them. As about a billion people cross international borders each year, many more billions of the bugs come along for the ride.

However, the trend is contributing to substantial domestic and international public health threats and risks, as seen with SARS and more recently with the H1N1 flu virus.

In a paper published today in Emerging Infectious Diseases (EID), a journal of the U.S. Centers for Disease Control and Prevention, a McMaster University infectious disease expert explores the relationship between population mobility, globalization and antimicrobial drug resistance.

In collaboration with a team of international scientists, Douglas MacPherson, an associate professor in the Department of Pathology and Molecular Medicine of the Michael G. DeGroote School of Medicine, assesses the link between human travel and the international movement of drug-resistant infectious diseases around the world.

Citing published data, the authors conclude that population mobility affects the spread and distribution of resistant organisms. But despite this, it has not been considered a primary factor in developing approaches for disease control. The authors propose a paradigm shift is needed to tackle the problem, as well as greater international collaboration and standardization across borders.

"The movement of human beings is introducing many of the greatest risks to our health and health systems today," said MacPherson, a physician and medical microbiology specialist.

"For example, if you go down south on a Florida holiday and break your leg and end up in a Florida hospital, when you come home, you're going to be carrying institutional bugs back to Hamilton and you're going to introduce that variety of antimicrobial resistance into your local environment. Mobile populations are probably the most common way of moving drug-resistant organisms around the world."

Using H1N1 influenza and other infectious diseases as examples, the EID paper concludes that the complexity of human movement exceeds current international disease control policies and practices.

The researchers suggest that an effective response requires engagement at the local level, standardization of practices, partnerships between a variety of sectors and rigorous health information gathering along with threat and risk assessment. They also recommend that mobile populations need to be taken into consideration when modelling drug resistance.

"It's not just about being reactive or responsive to the problem. We now have the ability to be more proactive in decision making, more integrative and more collaborative. That's how we'll get to better solutions," MacPherson said.

The authors recommend a new approach be developed to integrate population factors into health policy and processes, which have traditionally focused on specific diseases.

"A shift in the existing paradigm of pathogen-focused policies and programs to include the 'human factor' in health and disease would contribute to a healthier future for everyone," MacPherson said.

The ideas contained in the Emerging Infectious Diseases paper originated with the work of the Infectious Disease Information Expert Committee of the Council of Experts of the United States Pharmacopeia , an arm's length organization working with the U.S. government that establishes technical and analytic standards for all prescriptions, over-the-counter medicines and dietary supplements manufactured or sold in the United States and many other countries around the world, including Canada. MacPherson is the chair of the infectious disease committee and a member of the Council of Experts.


Contact: Veronica McGuire
McMaster University

Related medicine news :

1. Paradigm Spine Closes $21.5 Million Financing and Announces Promotion of Matt Stuttle to Position of Vice President, US Sales
2. Changing Paradigms in Hereditary Angioedema: A Focus on Timely Diagnosis and New Therapies
3. Changing Paradigms in Hereditary Angioedema: Pathophysiology, Diagnosis and Treatment
4. The Beryl Companies Reinvents Call Center, Shatters Old Paradigm
5. National Womens Health Report Addresses Issues of Uninsured Plus New Paradigms of Care
6. New CME guidelines advise paradigm shift in physician education
7. Cancer Researcher Dan Von Hoff, M.D. Advocates for "Context of Vulnerability," A Powerful New Paradigm for Targeted Drug Development
8. Topical treatment for cold sores achieves efficacy of oral drugs; represents paradigm shift
9. DIA Conference to Provide New Paradigms in Evidence-Based Medicine and Health Technology Assessment
10. New KLRI Reports Shows Longevity Science Moving Beyond Studying the Obvious to the Downward Spiral Paradigm in the Aging Process
11. Siemens New Ultrasound Platform Revolutionizes the Paradigm of Echocardiography
Post Your Comments:
(Date:6/27/2016)... ... June 27, 2016 , ... ... strategic partnership with Connance, a healthcare industry leader providing predictive analytics to ... technology combine to provide health systems, hospitals and ambulatory surgical centers with ...
(Date:6/26/2016)... ... 2016 , ... On June 10-11, 2016, A Forever Recovery, a holistic treatment ... Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility is located. This ... of the world’s leading providers of cereal and other breakfast foods. Its residents often ...
(Date:6/26/2016)... ... June 26, 2016 , ... Many women are confused ... endometriosis. These women need a treatment plan to not only alleviate symptoms and ... help for preservation of fertility and ultimately achieving a pregnancy. The specialists at ...
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand gesture animations, FCPX ... Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s package transforms over ... Cut Pro X . Simply select a ProHand generator and drag it above media ...
(Date:6/25/2016)... ... 25, 2016 , ... On Friday, June 10, Van Mitchell, Secretary of the ... to iHire in recognition of their exemplary accomplishments in worksite health promotion. , The ... Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was one ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 2016  Astellas today announced the establishment of Astellas Farma Colombia (AFC), a new affiliate with operations headquartered in ... America . ... ... ... ...
(Date:6/23/2016)... N.J. , June 23, 2016  Guerbet announced ... Premier Inc.,s Supplier Horizon Award . ... year, Guerbet was recognized for its support of Premier ... creation through clinical excellence, and commitment to lower costs. ... to receive this recognition of our outstanding customer service ...
(Date:6/23/2016)... DUBLIN , June 23, 2016 ... the "Surgical Procedure Volumes: Global Analysis (United States, ... Australia, Canada)" report to their offering. ... an essential tool for healthcare business planners, provides surgical ... looks at surgery trends with an in-depth analysis of ...
Breaking Medicine Technology: