Navigation Links
Panel of serum biomarkers may reduce number of lung biopsies needed
Date:3/15/2012

DENVER A panel of serum biomarkers could help predict the level of lung cancer risk in high-risk patients, offering doctors an option before proceeding with a biopsy. Research presented in the April 2012 issue of the International Association for the Study of Lung Cancer's (IASLC) Journal of Thoracic Oncology shows that a panel of 10 serum protein biomarkers could help in the lung cancer diagnosis. The biomarkers include: prolactin, transthyretin, thrombospondin-1, E-selectin, C-C motif chemokine 5, macrophage migration inhibitory factor, plasminogen activator inhibitor-1, receptor tyrosine-protein kinase erbB-2, Cyfra 21.1 and serum amyloid A. Further work is necessary to validate these exciting results.

In June, the National Lung Screening Trial showed that lung cancer deaths fell by 20 percent and all-cause mortality fell by 7 percent when heavy smokers were screened regularly using low-dose spiral computed tomography (CT) compared with standard chest x-ray. The problem is that often these screenings can present false positive results.

According to the study, "about 20 percent of the 1-2 cm nodules that are concerning enough to be considered for biopsy are actually malignant. Given the substantial risks of invasive diagnostic thoracic procedures, unselective biopsy of every person with a small nodule is clinically unacceptable."

The researchers conclude that these biomarkers have potential to aid in the early detection of lung cancer by adding to the information gathered by CT screening. The analysis was carried out from patients enrolled in the Pittsburgh Lung Screening Study, which is funded by the National Cancer Institute Specialized Program of Research Excellence (SPORE) in Lung Cancer.

The lead author of this work is Dr. William Bigbee and IASLC member co-authors include Dr. David Wilson, Dr. Jill Siegfried and Dr. Sanja Dacic.


'/>"/>

Contact: Kristal Griffith
Kristal.Griffith@IASLC.org
720-325-2952
International Association for the Study of Lung Cancer
Source:Eurekalert

Page: 1

Related medicine news :

1. Panel asks dairy avoiders: Are you getting enough?
2. Avoiding Dairy Due to Lactose Intolerance is Unnecessary in Most Cases and May Pose Diet and Health Risks, Concludes National Institutes of Health Consensus Development Conference Panel
3. All Global Launches Physician Panels in Russia and Poland
4. Panel questions VBAC bans, advocates expanded delivery options for women
5. Panel Finds Many Women Can Avoid Repeat C-Sections
6. Panel: Properly designed pay-for-performance models can support medical professionalism
7. Panel: FCCs Broadband Plan Will Boost Efforts to Expand Health IT
8. FDA Panel Weighs New Restrictions on Tanning Beds
9. R. Shane Jackson Selected as Panelist for Center for Health Transformation Member Meeting
10. Review Panel Leaves Controversial Lyme Disease Guidelines Unchanged
11. HIA-LI 22nd Annual Business Trade Show & Conference to Feature Healthcare Pavilion and Expert Panel Discussing Healthcare Economics and Politics
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/10/2016)... PLAINSBORO, N.J. (PRWEB) , ... ... ... J. Hennessy Associates, Inc. , a full-service health care communications company offering ... integrated digital news resource for practitioners and specialists working in infectious diseases. ...
(Date:2/10/2016)... ... February 10, 2016 , ... As part of its ongoing ... February 2016. Each webinar features a dynamic expert and thoughtful presentation to give ... patients and facilities. Both events are free to attend, but registration is ...
(Date:2/10/2016)... , ... February 10, 2016 , ... ... solution, The Guard, to associations of medical professionals throughout the country. The Guard ... security risk assessments, policies and procedures, employee training, regulatory updates, and compliance coaching. ...
(Date:2/10/2016)... ... February 10, 2016 , ... 10 Best Water is excited ... bottled water brand owners that topped the list as a result of their commitment ... The premier brand was Tibet 5100, a top notch water company that specializes in ...
(Date:2/10/2016)... ... ... Ongoing news of the ravages of traumatic brain injury (TBI) among former NFL ... a closer look at cases of TBI being managed by their members. The survey ... aging population, and identifies the challenges associated with their care. , During the week ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... Feb. 10, 2016 CSI Specialty Group (CSI) ... launch of the Specialty Pharmacy Podcast. A free, weekly ... at providing real-world education, discussion and context amongst specialty ... --> The Specialty Pharmacy Podcast, ... CSI Specialty Group Suzette DiMascio, CHE, CMCE, CPC, is ...
(Date:2/10/2016)... WOONSOCKET, R.I. , Feb. 10, 2016  CVS ... vaccines to people living in Santa Clara ... of Meningitis B on the Santa Clara University campus. ... vaccines available to protect patients against the disease. Students ... are encouraged to get vaccinated. In addition, anyone who ...
(Date:2/10/2016)... Feb. 10, 2016  Rich Pharmaceuticals, Inc. (OTC Markets: ... 1-for-100 reverse split of its issued and outstanding shares ... on Thursday, February 11, 2016. The Company,s common stock ... number 76303T308 and temporary ticker symbol "RCHAD". After 20 ... the ticker symbol (RCHA).  --> ...
Breaking Medicine Technology: