Navigation Links
Pandemic flu strain could point way to universal vaccine
Date:1/10/2011

American Recovery and Reinvestment Act of 2009.

The nine patients studied were recruited through the Hope Clinic, the clinical division of the Emory Vaccine Center. They had a range of disease severities, from mild illness that waned after a few days to a severe case that required a two-month hospital stay including ventilator support. Most of the participants were in their 20s or 30s. Blood samples were usually taken about 10 days after the onset of symptoms.

The team of researchers identified white blood cells from the patients that made antibodies against flu virus, and then isolated the antibody genes from individual cells. They used the genes to produce antibodies in cell culture -- a total of 86 varieties -- and then tested which flu strains they reacted against.

Five antibodies isolated by the team could bind all the seasonal H1N1 flu strains from the last decade, the devastating "Spanish flu" strain from 1918 and also a pathogenic H5N1 avian flu strain.

Seasonal flu shots contain three inactivated viral strains, each grown in chicken eggs. Over the last decade, it was standard that one of the three is an H1N1 strain. However, vaccination with any one H1N1 strain doesn't usually result in protection against all of them that's why the 2009 strain could make so many people sick.

Some of the antibodies the team identified stick to the "stalk" region of part of the virus (a protein called hemagglutinin). Because this part of the virus doesn't change as much as other regions, scientists have proposed to make it the basis of a vaccine that could provide broader protection.

"Previously, this type of broadly protective, stalk-reactive antibody was thought to be very rare," Wrammert says. "In contrast, in the patients we studied, these stalk-reactive antibodies were surprisingly abundant."

The team tested whether three of the antibodies they isolated could protect mice against the 2009 H1N1 strain or two
'/>"/>

Contact: Holly Korschun
hkorsch@emory.edu
404-727-3990
Emory University
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Most pandemic plans in Ontario hospitals have not been tested: Queens University study
2. America's Hidden Pandemic: 100 Million Suffer From Sleep Problems
3. Pandemic flu, like seasonal H1N1, shows signs of resisting Tamiflu
4. Personalizing medicine to prevent pandemics
5. Hand-washing, mask-wearing may limit transmission of pandemic flu
6. Fear of pandemic influenza clogs EDs even when disease is not present
7. Good Hygiene Does Slow Spread of Pandemic Flu
8. H1N1 Pandemic Flu Hits Pregnant Women Hard
9. NIH-funded scientists find 2009 H1N1 pandemic influenza vaccine protects mice from 1918 flu virus
10. H1N1 Pandemic Flu Even Milder Than Seasonal Strains
11. Disease transmission model says media coverage cuts infection rate and pandemic extent
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2015)... April 24, 2015 Ryadon is a ... range of capabilities and services to complement any custom ... Quantity Discount Program will be offered on all heavy ... Order 4-19: Receive 10% discount - Order 20+: Receive ... the Drawer Slides Products, Furniture ...
(Date:4/24/2015)... TX (PRWEB) April 24, 2015 The Fastest ... Long, after their great success of the Xtreme Fat Loss ... industry. The fat loss blueprint that claims to help ... the attention of HealthyandFitZone.com's Stan Stevenson, prompting an investigative review. ... shows that the creators spent years researching and experimenting with ...
(Date:4/24/2015)... (PRWEB) April 24, 2015 The 1975 ... toured almost constantly across the globe to theaters, festivals and ... in Manchester, they’ve partnered with their label, Dirty Hit Records, ... Teaming up with the newly launched Cadence & Cause ... their debut LP on vinyl and a signed photo card. ...
(Date:4/24/2015)... 24, 2015 The first step to ... mind. , For meditation and yoga teacher Stine Koppernæs, ... been invaluable tools that allow her to experience more ... has been a teacher since 2006, and through the ... state of being. , “I love sharing this way ...
(Date:4/24/2015)... (PRWEB) April 24, 2015 Carinsurancequotesinfo.com has ... blog post explaining how to qualify for auto ... parents can qualify for auto insurance online, without having ... post explains that single parents can reduce their auto ... released article and properly explained. , Clients can ...
Breaking Medicine News(10 mins):Health News:Ryadon Inc. Offers Quantity Drawer Slide Discount Program Nationwide in May 2015 2Health News:Ryadon Inc. Offers Quantity Drawer Slide Discount Program Nationwide in May 2015 3Health News:Fastest Fat Loss Week Ever Review Revealed on Healthy & Fit Zone 2Health News:Internationally Recognized British Indie Rock Outfit The 1975 Partner with Cadence & Cause to Provide Clean Drinking Water to Those in Need 2Health News:Auto Insurance Discounts for Single Parents - How to Qualify for Low Rates 2
... Kennedy To Be Honored for Leadership on Right to Health , ... ... Medical School in Boston, community members and experts join for a landmark ... U.S. and Globally., The event, which commemorates World AIDS Day and the ...
... of a new initiative to create partnerships with pediatric ... has signed a memorandum of understanding with the department ... , The memorandum is the first among Mattel ... Asia and Latin America. , ...
... American application activity for individually underwritten life insurance was down ... Index (SM). Year to date (YTD) U.S. and ... months last year. November,s activity was off -0.9% as ... U.S. application activity was down -1.8% in November ...
... Christmas Story", Ralphie sets out to convince the world that a Red ... "You,ll shoot your eye out!" was the response he got ... more hilarious and memorable quotes from this Christmas classic because we,ve all ... too many people. , , It,s hard ...
... MORTON GROVE, Ill., Dec. 5 Lifeway Foods, Inc.,(Nasdaq: ... today new distribution of its 12 pack "club pack" to the ... addition to the,expansion of the Costco Midwest region from 20 stores ... of December 2008 and consumers can,expect to find the product in ...
... tumors boosts chances for those denied under current protocols, study ... patients with liver cancer who don,t meet criteria used to ... transplantation, according to an Italian study. , The Milan criteria ... 5 centimeters or less in diameter, or three or fewer ...
Cached Medicine News:Health News:Community Unites for Physicians for Human Rights Town Meeting on Global AIDS and Human Rights on December 8 2Health News:Community Unites for Physicians for Human Rights Town Meeting on Global AIDS and Human Rights on December 8 3Health News:Community Unites for Physicians for Human Rights Town Meeting on Global AIDS and Human Rights on December 8 4Health News:Community Unites for Physicians for Human Rights Town Meeting on Global AIDS and Human Rights on December 8 5Health News:Community Unites for Physicians for Human Rights Town Meeting on Global AIDS and Human Rights on December 8 6Health News:MIB Life Index Reports North American Life Insurance Activity Off 1.9% in November 2Health News:Oklahoma Parents Can Prevent Holiday Tragedies with Safe Toys and Celebrations 2Health News:Lifeway Foods Announces New East Coast and Expanded Midwest Distribution 2Health News:New Criteria Could Expand Number of Liver Transplant Candidates 2
(Date:4/24/2015)... -- Allowing more basic emergency medical service (EMS) staff ... involve opioids, according to a Centers for Disease Control ... Emergency Medical Service Providers and the Burden of Drug ... Journal of Public Health . In 2013, ... States involved prescription opioids, and more than ...
(Date:4/24/2015)... 24, 2015  New technologies and online platforms ... educate themselves about products and companies. Likewise, these ... available to market researchers seeking insights into consumer ... it,s imperative that organizations adjust their consumer marketing ... opportunities, niches and growth fronts. ...
(Date:4/24/2015)... 2015 Boston Scientific Corporation (NYSE: BSX ) ... Annual Healthcare Conference on May 6 in ... vice president and chief financial officer, and Susie Lisa ... question and answer session regarding the company with the host ... webcast of the presentation and question and answer session will ...
Breaking Medicine Technology:Expanding Naloxone use could reduce drug overdose deaths and save lives 2Expanding Naloxone use could reduce drug overdose deaths and save lives 3Pharmaceutical Industry Using New Technologies to Adjust Their Marketing and Research Approaches for Consumers 2Boston Scientific To Participate In The Deutsche Bank 40th Annual Healthcare Conference 2
... Calif., April 7, 2011 MEDomics, LLC provides ... medicine in the genomics era and is transforming ... to announce a growth capital investment from our ... from SpaGus will be used by MEDomics to ...
... Pharmaceuticals Inc. today announced that Prabhavathi Fernandes, Ph.D., president ... CHI conferences.  Dr. Fernandes will present at the ... 5 p.m. PDT, April 12, at the Hilton San ... "Macrolides as a New Class of Orally Active Anti-Inflammatory ...
Cached Medicine Technology:MEDomics Announces a Growth Capital Investment from SpaGus Ventures LLC and Gary Augusta Joins MEDomics as Chief Operating Officer 2Cempra Pharmaceuticals to Present at Two Upcoming Cambridge Healthtech Institute (CHI) Conferences 2
... The unique triple-mode technology ... all-around system for an array ... technology includes a patented, controllable ... mode for classical ablation procedures, ...
... is the only in-office test approved by the ... NMP22 BladderChek Test is a painless and non-invasive ... detects elevated levels of NMP22 protein. Healthy individuals ... in the urine. However, the level of NMP22 ...
ARION is a long-pulsed alexandrite laser system with a wavelength of 755 nm...
Used for measuring rectal pressure during urodynamic studies. All-silicone construction provides maximum softness and biocompatibility for enhanced patient comfort. Supplied sterile in peel-open pack...
Medicine Products: