Navigation Links
Pandemic flu, like seasonal H1N1, shows signs of resisting Tamiflu
Date:3/1/2010

ess frequent use of the drug or to the possibility that mutations leading to resistance to Relenza aren't tolerated by the virus itself, so those strains die off.

Janies noted that there is another phenomenon with flu that could further make the pandemic strains difficult to treat. In at least 50 geographic regions identified by the analysis, both seasonal and pandemic H1N1 viruses are co-circulating, including Tamiflu-resistant strains. Because the flu virus in general is not precise when it makes copies of itself, this means that a drug-susceptible pandemic strain might exchange a gene with a drug-resistant viral strain and add it to the new genome.

"And then we would have drug-resistant pandemic influenza without any mutation. It's a random swap of the whole gene," Janies said of this phenomenon, which is called reassortment.

"That's how we got into this situation with pandemic influenza. We have something that's called pandemic H1N1, but all of its internal genes are different. It underwent a few rounds of reassortment and it's a virus we've never seen before because its genome is highly reshuffled compared to seasonal H1N1. This same process could confer resistance to a drug," he said.

The researchers have plotted areas where pandemic influenza and drug-resistant seasonal influenza circulate together into Google Earth using software called Pointmap. Regions in the United States and Japan are among those in which pandemic flu isolates carry the Tamiflu-resistant mutation. The regions of co-circulation can be seen at http://pointmap.osu.edu.


'/>"/>

Contact: Daniel Janies
daniel.janies@osumc.edu
614-292-1202
Ohio State University
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. HHS Announces $75 Million in Supplemental Funding to States for Pandemic Flu Preparedness
2. CEO Addresses Tennessee Business Leaders About Developing Pandemic and Business Continuity Plans
3. Peer-Reviewed, Online Database Showcases Local, County and State Pandemic Planning
4. New Report Says a Pandemic is Overdue, But Companies and Nations are ill Prepared to Cope With the Impact
5. Report highlights inadequate pandemic planning as a threat to EU security
6. AIDS Ignorance: One-Third of Adults Admit Little or No Knowledge of Pandemic
7. Global Summit on AIDS & The Church Calls for Public, Private and Parish Sectors To Unite in Response to Worldwide Pandemic: Pastor Rick and Kay Warren Host More Than 1,700 at Event Featuring International Dignitaries, Political Figures and International E
8. Vical Expands Clinical Testing of DNA Vaccine Against H5N1 Pandemic Influenza
9. CEO Addresses Georgia Business Leaders About Developing Pandemic and Business Continuity Plans
10. iJET Unveils 2007 Year-in-Review Report on Avian Influenza and Pandemic Planning
11. Flu Pandemic: Is the U.S. Ready?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/2/2015)... King of Prussia, PA (PRWEB) June 02, 2015 ... Business Process Outsourcing solutions for health plans in the ... announces their participation as a sponsor and exhibitor at ... trade group, America’s Health Insurance Plans. The conference will ... TMG Health exhibition booth, #1303, will offer opportunities for ...
(Date:6/2/2015)... Radaris ” was featured on NewsWatch as part of its ... coolest applications on the market for iOS, Android, and Windows. ... the app review and shared with viewers can help users ... According to Psychology Today, humans are a curious species by ... is a part of human development. People are using the ...
(Date:6/2/2015)... June 02, 2015 Did you wish Ryder ... to get him, his family isn’t asking for presents, but ... team walking in Saturday’s Cure HHT DC Walk. , Ryder ... that causes malformed blood vessels leading to sudden and extreme ... appear when Ryder was 3 years old in the form ...
(Date:6/2/2015)... Grenoble, France, and Dallas, TX, USA (PRWEB) June 02, ... of innovative nano and microsystems, is deploying its growth ... healthcare applications, focusing on BioMEMS: “In Yole Développement’s May ... that the BioMEMS market will grow sharply and reach ... MEMS & Sensors at Yole Développement . , ...
(Date:6/2/2015)... Milton Hershey School® graduate Vincent Klomps ’10 ... of the Physician Assistant Program’s entering class of 2015 ... with a white coat, which symbolizes his entrance into ... of Vincent’s accomplishments both at MHS and postgraduation,” said ... of how a top-notch education can lead to achievement ...
Breaking Medicine News(10 mins):Health News:TMG Health to Sponsor and Exhibit at AHIP’s Institute 2015 2Health News:A Comprehensive People Search Application Was Featured on NewsWatch Television 2Health News:Six-Year-Old Walks to Bring Awareness to Genetic Disease 2Health News:Tronics Aims to Benefit from Major Growth of Sensors and Related Technologies for Healthcare Applications 2
... Lube Leader Reaches Halfway Point in Campaign to Support American ... Heart Association,s Go Red For Women(TM) Movement, HOUSTON, Feb. ... to its goal of raising $1 million for the,American Heart ... Heart Month are almost in the rear-view mirror, Jiffy,Lube wants ...
... according to a study of more than 77,000 vitamin ... risk of developing it. , Our study of supplemental ... show any evidence for a decreased risk of lung ... of the University of Washington, in Seattle. Indeed, increasing ...
... and a decision algorithm, rather than standard hospital protocols, ... patients with severe sepsis or septic shock can reduce ... costs all without adverse effects on patients, according to ... possible to customize antibiotic treatment duration in patients with ...
... UT Southwestern Medical Center have determined that the level, or ... children with sickle cell anemia who are at an increased ... have also found that a published method used to predict ... , Stroke is a serious but increasingly preventable complication of ...
... affected by ... rare diseases, NEW YORK, Feb. ... Day will be launched on Friday 29,February...because it,s a rare day that ... Shire plc at:, http://media.medialink.com/WebNR.aspx?story=34701 ), Collectively, rare diseases aren,t ...
... to Reliance on Spill-Proof,Cups, GLENDALE, Calif., Feb. 28 ... Dental Hygienists, Association,(CDHA) today urged parents and caregivers to ... "We all know that sippy cups are a godsend ... "But they need to be used wisely and,properly in ...
Cached Medicine News:Health News:Jiffy Lube(R) Continues Drive Against Heart Disease with Maintenance Partners for Life Campaign 2Health News:Jiffy Lube(R) Continues Drive Against Heart Disease with Maintenance Partners for Life Campaign 3Health News:Jiffy Lube(R) Continues Drive Against Heart Disease with Maintenance Partners for Life Campaign 4Health News:Certain vitamin supplements may increase lung cancer risk, especially in smokers 2Health News:Customized treatments for sepsis lower treatment time and reduce length of ICU stays 2Health News:UT Southwestern researchers investigate predictors for sickle-cell-anemia complications 2Health News:VIDEO from Medialink and Shire plc: Rare Diseases Must Be Top of the Health Agenda 2Health News:VIDEO from Medialink and Shire plc: Rare Diseases Must Be Top of the Health Agenda 3Health News:California Dental Hygienists Offer Tips for Safe Sippy Cup Use 2
(Date:6/2/2015)... DUBLIN , June 02, 2015 Research ... of the "Europe Fluoroscopy Market - Growth, Trends ... offering. The European market for Fluoroscopy is ... to 2020 Fluoroscopy is used to view ... catheter through blood vessels, bile ducts or the urinary ...
(Date:6/2/2015)... , June 02, 2015 Research and Markets( ... Mammography Market - Growth, Trends And Forecasts (2014 - 2019)" ... market is dominated by the Germany . ... . Developing nations such as Poland ... for mammography equipment can be segmented on the basis of ...
(Date:6/2/2015)... -- Research and Markets ( http://www.researchandmarkets.com/research/w3n5p6/drug_delivery_in ) has ... "Drug Delivery in Central Nervous System Diseases ... offering. The delivery of drugs to ... the treatment of neurological disorders. Drugs may be ... (e.g., by intravenous injection) for targeted action in ...
Breaking Medicine Technology:European Fluoroscopy Market Report 2014-2019 - Growth, Trends And Forecasts 2Europe Mammography Market Report 2014-2019 - Growth, Trends And Forecasts 2Global Drug Delivery in Central Nervous System Diseases Report 2015-2024 - Technologies, Markets and Companies 2Global Drug Delivery in Central Nervous System Diseases Report 2015-2024 - Technologies, Markets and Companies 3
... , WALTHAM, Mass., Dec. 9 Decision Resources, one ... pharmaceutical and healthcare issues, finds that compared to last year,s ... used more often to treat newly diagnosed patients suffering from ... received a TNF-alpha inhibitor versus one year ago (15.2 percent ...
... , NEW ... research report is available in its catalogue: , Medical ... http://www.reportlinker.com/p0164322/Medical-Fiber-Optics---A-World-Market-Analysis.html , Fiber optics work on the principle ... an element encased by glass in air of low refractive ...
Cached Medicine Technology:TNF-Alpha Inhibitors Are Being Used More Often To Treat Newly Diagnosed Patients With Crohn's Disease 2TNF-Alpha Inhibitors Are Being Used More Often To Treat Newly Diagnosed Patients With Crohn's Disease 3Reportlinker Adds Medical Fiber Optics - A World Market Analysis 2Reportlinker Adds Medical Fiber Optics - A World Market Analysis 3Reportlinker Adds Medical Fiber Optics - A World Market Analysis 4Reportlinker Adds Medical Fiber Optics - A World Market Analysis 5Reportlinker Adds Medical Fiber Optics - A World Market Analysis 6
... First access to the skull by trepanation. ... performance motor at standard operating pressure: 6 ... coupling. Full manual control by a progressive ... with drilling speed of approx. 800 rpm. ...
14 cm - 5 1/2, 6.0 mm , for drill handles and hand drills....
DeMartel (Bailey) Wire Saw Guide, 33 cm - 13, flexible....
Galt Skull Trephine with adjustable centering point and detachable cross-bar handle, 19.0 mm....
Medicine Products: