Navigation Links
Pandemic flu, like seasonal H1N1, shows signs of resisting Tamiflu
Date:3/1/2010

nies said. "We can see it happening already.

"This has potential to indicate that we are going to have to think of something else to use to treat pandemic H1N1 influenza."

The same study showed that resistance to a second antiviral drug zanamivir, known by the brand name Relenza is not as prevalent, suggesting this medication might be a good alternative to Tamiflu, he said.

The research appears online in the International Journal of Health Geographics.

So far, most pandemic H1N1 strains that have been isolated from humans are susceptible to Tamiflu. As of Feb. 3, 2010, 225 cases of pandemic H1N1 were reported to be resistant to the drug out of the predicted millions of cases of illnesses with swine flu across the United States and elsewhere in the world.

But those resistant cases, as well as the way mutations have led to Tamiflu resistance in seasonal H1N1, offer clues about how the virus changes itself to survive against the popular drug.

The two types of H1N1 virus, seasonal and pandemic, are similar on the surface, where their proteins interact with cells in the human body. But the internal genes of the viruses are configured differently.

The researchers zeroed in on specific points in the neuraminidase protein this protein is what the "N" refers to in these virus subtype names. Resistance to oseltamivir in H1N1 can evolve as a result of a point mutation at one of several locations on this protein, Janies said.

He and colleagues analyzed mutations in neuraminidase proteins from 1,210 seasonal H1N1 viruses isolated around the world between September 2004 and December 2009. For pandemic H1N1, the researchers examined mutations in specific points on neuraminidase proteins of 1,824 viruses collected between March 2009 and December 2009.

"With the rapid availability of public sequence data on pandemic influenza, we are able to essentially watch evolution in real time," Janies
'/>"/>

Contact: Daniel Janies
daniel.janies@osumc.edu
614-292-1202
Ohio State University
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. HHS Announces $75 Million in Supplemental Funding to States for Pandemic Flu Preparedness
2. CEO Addresses Tennessee Business Leaders About Developing Pandemic and Business Continuity Plans
3. Peer-Reviewed, Online Database Showcases Local, County and State Pandemic Planning
4. New Report Says a Pandemic is Overdue, But Companies and Nations are ill Prepared to Cope With the Impact
5. Report highlights inadequate pandemic planning as a threat to EU security
6. AIDS Ignorance: One-Third of Adults Admit Little or No Knowledge of Pandemic
7. Global Summit on AIDS & The Church Calls for Public, Private and Parish Sectors To Unite in Response to Worldwide Pandemic: Pastor Rick and Kay Warren Host More Than 1,700 at Event Featuring International Dignitaries, Political Figures and International E
8. Vical Expands Clinical Testing of DNA Vaccine Against H5N1 Pandemic Influenza
9. CEO Addresses Georgia Business Leaders About Developing Pandemic and Business Continuity Plans
10. iJET Unveils 2007 Year-in-Review Report on Avian Influenza and Pandemic Planning
11. Flu Pandemic: Is the U.S. Ready?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2014)... Boston, MA (PRWEB) July 23, 2014 ... professional medical education to a community of more than ... of Medicine Ultrasound Institute will launch a national continuing ... primary care clinicians about new advancements in ultrasound and ... , Pri-Med and the University of South Carolina School ...
(Date:7/23/2014)... QueenBeeTickets.com is reducing the prices of History of The Eagles ... who are still in the process of looking for concert ... use promo code “DISCOUNT” to get even lower prices than ... of discounted tickets at QueenBeeTickets.com. , The phenomenal band will ... The Eagles concert tickets literally disappearing across the country. The ...
(Date:7/23/2014)... 2014 ISI Telemanagement Solutions, Inc., a ... Infortel Speech Analytics, a new product as part ... Analytics gives users the ability to uncover vital customer ... , as well as chat sessions and social media ... be new, adding speech analytics on to a recording ...
(Date:7/23/2014)... According to the latest market reports compiled ... region, the Northern Virginia real estate market ... quickly throughout the area, and median sale prices have ... Virginia market includes the city of Alexandria, and Arlington, ... Virginia region saw median sale prices increase in some ...
(Date:7/23/2014)... Online medical service provider MeMD has appointed ... Dr. Lorenzo joins the MeMD executive team with over ... a part of this remote treatment model, telemedicine. This is ... in medical school, that someday we could treat people across ... here and it hasn't been that long,” says Dr. Lorenzo. ...
Breaking Medicine News(10 mins):Health News:Pri-Med and the University of South Carolina School of Medicine Launch National Ultrasound Education Initiative for Primary Care Clinicians 2Health News:Pri-Med and the University of South Carolina School of Medicine Launch National Ultrasound Education Initiative for Primary Care Clinicians 3Health News:History of The Eagles Tour Tickets: QueenBeeTickets.com Reduces Prices on Remaining Inventory of Concert Tickets for 2014 Shows 2Health News:ISI Telemanagement Solutions, Inc. Releases Infortel® Speech Analytics 2Health News:ISI Telemanagement Solutions, Inc. Releases Infortel® Speech Analytics 3Health News:Northern Virginia Real Estate Company Pasquali Realty Group Announces Median Sale Price Increased in the Region in June 2014 2Health News:Telemedicine Provider MeMD Announces Nicholas Lorenzo, MD, MHCM, CPE as Chief Medical Officer 2Health News:Telemedicine Provider MeMD Announces Nicholas Lorenzo, MD, MHCM, CPE as Chief Medical Officer 3
... Group, Inc. (Phyhealth) (Pink Sheets: PHYH), a developer of,health ... its board of directors has approved a stock buyback,program ... Common Stock., The shares will be purchased on ... be made at the Company,s discretion and can begin ...
... NEW YORK, Oct. 30 The American Fertility ... educational program,which brings young women together in a ... "dos and don,ts" of preserving fertility. It,s,free, relaxing, ... 20 U.S.,cities and be hosted by leading professionals ...
... Trane CleanEffects(TM) Reduces Dust by Half While Helping to ... Prevent Allergy Symptoms and Asthma Attacks, TYLER, ... Engineering Inc. (EH&E) and professors at the,Harvard School of Public ... reduces dust accumulation in,the home by more than 50 percent ...
... change when clocks are adjusted , , WEDNESDAY, Oct. 29 (HealthDay ... about here, and it may pose problems more serious than ... in the number of heart attacks following the semi-annual one-hour ... "This was the very first study on this topic and ...
... 30 Cardo Medical, a company engaged,in the ... 510k,clearance of its Align 360 Total Knee System. ... commercial release during the second quarter of 2009.,Cardo ... product within,its Align 360 platform which has already ...
... 30 Eclipsemed, Ltd is pleased to announce,availability ... Human Med based in Germany. Body-Jet is the ... safer liposuction option., While traditional liposuction basically ... requiring impact on the fat cell itself.,Body-Jet uses ...
Cached Medicine News:Health News:Phyhealth Announces Stock Buyback Program 2Health News:Phyhealth Announces Stock Buyback Program 3Health News:The American Fertility Association Announces Plan to Help Young Women Preserve Fertility 2Health News:Studies Reveal Every Homeowner's Dream: You Can Dust Less and Have a Healthier, Cleaner Home 2Health News:Studies Reveal Every Homeowner's Dream: You Can Dust Less and Have a Healthier, Cleaner Home 3Health News:Semi-Annual Time Changes May Affect the Heart 2Health News:Semi-Annual Time Changes May Affect the Heart 3Health News:Cardo Medical Announces FDA Clearance of the Align 360 Total Knee System 2Health News:Cardo Medical Announces FDA Clearance of the Align 360 Total Knee System 3Health News:Body-Jet Water-Assisted Liposuction Establishes New Standard for Liposuction and Fat Harvesting 2
(Date:7/23/2014)... 23, 2014 Sinovac Biotech Ltd. (NASDAQ: ... China , announced today that it has been ... ("Beijing CDC") to be a supplier of the seasonal influenza ... for 2014. The Beijing CDC plans to order ... vaccine this year from four domestic vaccine manufacturers for its ...
(Date:7/23/2014)... , Indien, July 23, 2014 /PRNewswire/ ... additional scope für Arbeiten für Sadara Chemical ... comprehensive Engineering Information System innerhalb des integrierten ... Dieser award of additional scope im Wert ... des zuvor abgeschlossenen Vertrags dar, dessen Wert ...
(Date:7/22/2014)... -- Nektar Therapeutics (Nasdaq: NKTR ) will announce its ... on Thursday, July 31, 2014, after the close of U.S.-based ... officer, will host a conference call to review the results ... (PT). The press release and a live ... a link that is posted on the home page and ...
Breaking Medicine Technology:Sinovac Receives Beijing CDC Tender to Supply Seasonal Flu Vaccine Anflu 2Rolta gewinnt Follow-on Award für Engineering Systems für Sadara, Saudi-Arabien im Wert von mehreren Millionen Dollar 2Rolta gewinnt Follow-on Award für Engineering Systems für Sadara, Saudi-Arabien im Wert von mehreren Millionen Dollar 3Rolta gewinnt Follow-on Award für Engineering Systems für Sadara, Saudi-Arabien im Wert von mehreren Millionen Dollar 4Nektar to Announce Financial Results for the Second Quarter 2014 on Thursday, July 31, 2014, After Close of U.S.-Based Financial Markets 2Nektar to Announce Financial Results for the Second Quarter 2014 on Thursday, July 31, 2014, After Close of U.S.-Based Financial Markets 3
... speech today to the City Club of San Diego, John ... Lilly and Company (NYSE: LLY ), said that the ... vision for biopharmaceutical companies to "reinvent innovation" to make the ... and address unmet medical needs. Lechleiter,s remarks came the ...
... 30 Physicians at St. David,s South Austin Hospital ... Lead-extraction is a complicated procedure to remove leads, or ... or other implanted Cardiac Rhythm Management (CRM) devices. Recent ... a safe and effective way to remove cardiac leads ...
Cached Medicine Technology:Lilly CEO Lechleiter Calls for Repair of the 'Engine of Biopharma Innovation' 2Lilly CEO Lechleiter Calls for Repair of the 'Engine of Biopharma Innovation' 3St. David's South Austin Hospital Leading the Central Texas Region in Laser-Assisted Lead-Extraction Procedures 2St. David's South Austin Hospital Leading the Central Texas Region in Laser-Assisted Lead-Extraction Procedures 3
The Maverick Over-The-Wire balloon catheter delivers a new level of performance to meet the changing demands of interventional cardiology....
... dials to make it easier and more ... setting of the exam room. Put away ... off throughout the entire process. The Illuminated ... cylinder axis scales that are easier than ...
... The full color LCD screen, ... joystick controls, enable any member ... quick and accurate measurements.,Measurement data ... color screen, and results can ...
... who need punctal occlusion want ... relief. They also want their ... comfortable and as unobtrusive as ... punctal plugs are growing in ...
Medicine Products: