Navigation Links
Pancreas May Be Key to Pregnancy-Linked Diabetes
Date:11/1/2007

The condition can pose dangers to mother, baby, experts note

THURSDAY, Nov. 1 (HealthDay News) -- New information about a protein in the pancreas may help in efforts to determine how diabetes develops during pregnancy, say Stanford University Medical Center researchers.

About 5 percent of women develop so-called gestational diabetes, which is a leading cause of birth defects and can predispose children to developing diabetes later in life.

In research with mice, the Stanford team focused on a protein called menin, which is known to have a role in preventing cancer in the pancreas and other organs. Menin prevents pancreatic cancer by blocking the growth of pancreatic cells.

However, insulin-producing islet cells in the pancreas need to grow during pregnancy in order to produce enough insulin. Therefore, the pancreas produces less menin during pregnancy. After pregnancy, menin levels go back to normal, and the islet cells return to their original size, the researchers explained.

They created mice that produced too much menin and found that there was insufficient islet growth during pregnancy, resulting in gestational diabetes.

"This suggests that there is an internal code for controlling pancreatic islet growth, a code we intend to crack," senior author Dr. Seung Kim, associate professor of developmental biology, said in a prepared statement.

Kim's team also found that the amount of menin present in the pancreas is regulated by a hormone called prolactin, which is abundant in pregnant women.

The research is published in the Nov. 2 issue of the journal Science.

More information

The U.S. National Institute of Child Health and Human Development has more about gestational diabetes.



-- Robert Preidt



SOURCE: Stanford University Medical Center, news release, Nov. 1, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Pancreas transplant gives hope to type 2 diabetes
2. Pancreas Transplant for Diabetics
3. Stomach Bruises Can Lead To Pancreas Infection
4. Once-Diabetic Heart/Kidney/Pancreas Transplant Recipient Enjoys Life (And Eating Again)
5. Mutated Gene Zaps Pancreas Cancer in Mice
6. Is Diabetes the Leading Cause of Kidney Failure in India
7. Diabetes and Depression often go hand-in-hand
8. Vitamin E, the latest warrior against diabetes
9. Thirty minutes of work up per day reduces the risk of Diabetes
10. New Drug for Diabetes
11. Diabetes, obesity rates shooting up
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... 26, 2016 , ... On June 10-11, 2016, A Forever Recovery, a holistic ... World’s Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility is located. ... some of the world’s leading providers of cereal and other breakfast foods. Its residents ...
(Date:6/25/2016)... ... June 25, 2016 , ... Experts ... applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes Convention ... health care topics including advance care planning, healthcare costs and patient and family ...
(Date:6/25/2016)... Long Beach, CA (PRWEB) , ... June 25, 2016 , ... ... from UCLA with Magna Cum Laude and his M.D from the David Geffen School ... San Diego and returned to Los Angeles to complete his fellowship in hematology/oncology at ...
(Date:6/24/2016)... Marne, Michigan (PRWEB) , ... June 24, 2016 , ... ... To deal with these feelings, many turn to unhealthy avenues, such as drug or ... Center of Marne, Michigan, has released tools for healthy coping following a traumatic event. ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas of ... AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Dehaier Medical Systems Ltd. (NASDAQ: DHRM ) ... medical devices and wearable sleep respiratory products in ... with Hongyuan Supply Chain Management Co., Ltd. (hereinafter referred ... to develop Dehaier,s new Internet medical technology business. ... Hongyuan Supply Chain,s sales platform to reach Dehaier,s dealers ...
(Date:6/24/2016)... -- According to a new market research ... Safety Pen Needles), Needle Length (4mm, 5mm, 6mm, 8mm, ... Purchase (Retail, Non-Retail) - Trends & Global Forecasts to ... for the forecast period of 2016 to 2021. This ... 2021 from USD 1.65 Billion in 2016, growing at ...
(Date:6/24/2016)... , June 24, 2016  Arkis BioSciences, ... less invasive and more durable cerebrospinal fluid treatments, ... funding.  The Series-A funding is led by Innova ... Fund, and other private investors.  Arkis, new financing ... instrumentation and the market release of its in-licensed ...
Breaking Medicine Technology: