Navigation Links
Palatin Technologies, Inc. Announces PL-3994 Poster Presentation at 2009 Heart Failure Society of America Annual Meeting
Date:9/15/2009

CRANBURY, N.J., Sept. 15 /PRNewswire-FirstCall/ -- Palatin Technologies, Inc. (NYSE Amex: PTN) announced that a poster on clinical trial results with PL-3994, its product for heart failure, will be presented today at the 13th Annual Scientific Meeting of the Heart Failure Society of America in Boston.

The poster presents data from a Phase 2A study of PL-3994 in controlled hypertensive volunteers who were taking antihypertensive medications and otherwise healthy. The study is preparatory to planned future trials, in which heart failure patients will receive daily subcutaneous injections of PL-3994 with the objective of reducing the re-hospitalization rate in heart failure patients after an acutely decompensating event.

"This study supports our hypothesis that PL-3994 can safely be administered to patients receiving antihypertensive medications, such as heart failure patients," said Trevor Hallam, Ph.D., Executive Vice President of Research and Development of Palatin. "We are excited by the potential for PL-3994, which is the only reported natriuretic peptide drug being developed for daily, subcutaneous, self-administration by heart failure patients."

Key Results

PL-3994 was administered by subcutaneous injection to volunteers with controlled hypertension, with key results including:

  • Increases in plasma concentrations of cyclic guanosine monophosphate (cGMP) levels, a pharmacological response consistent with the effects of endogenous natriuretic peptides on cardiovascular function, similar to results seen in an earlier Phase 1 study.
  • A maximum tolerated dose of 0.3 micrograms per kilogram, based upon a pre-specified decrease in blood pressure.
  • PL-3994 was well tolerated, with no serious adverse events observed in t
    '/>"/>

SOURCE Palatin Technologies, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Palatin Technologies to Present at the Acumen BioFin Rodman & Renshaw 9th Annual Healthcare Conference
2. Palatin Technologies, Inc. Reports Fiscal Year 2008 Second Quarter Results; Teleconference and Webcast to be held on February 11, 2008
3. Palatin Technologies Announces Receipt of $4.1 Million from AstraZeneca
4. Palatin Technologies to Present at Cowen Annual Health Care Conference on March 19, 2009
5. Palatin Technologies, Inc. Reports Fiscal Year 2009 Third Quarter Results; Teleconference and Webcast to be held on May 15, 2009
6. ReBuilder Medical Technologies, Inc. Reports International Sales Expansion
7. ReBuilder Medical Technologies, Inc. Signs Agreement for Distribution in Maine
8. MedCom USAs Subsidiary Card Activation Technologies, Inc.s SB2 Registration Declared Effective by SEC
9. Neurobiological Technologies, Inc. Announces Receipt of Determination Letter from NASDAQ
10. ReBuilder Medical Technologies, Inc. Increases Staffing by 30% in Three Weeks Due to Increase in Demand for All ReBuilder Medical Products
11. ReBuilder Medical Technologies, Inc. Reports Monthly Sales in 2007 Nearly Doubling Monthly Sales in 2006, Including Record Daily Sales in September 2007
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/29/2014)... (PRWEB) September 30, 2014 NAPW ... Clinical Manager Specialist, as a 2014 Professional Woman of ... distinction for leadership in clinical care. As the largest ... virtually every industry and profession, the National Association of ... over 600,000 members and nearly 300 Local Chapters. , ...
(Date:9/29/2014)... Every autumn, as high school and college gets ... takes off! Athletes typically train throughout the summer in ... the leading compression apparel company, makes the best ... for cross country running. , The compression leg ... muscle soreness (DOMS) throughout training in addition to speeding ...
(Date:9/29/2014)... 2014 China’s regulatory framework for ... country’s new leaders have recognized that the regulations ... are far from perfect along with rapid population ... years. Chinese state council issued the latest “Regulations ... on February 12, 2014, and it has come ...
(Date:9/29/2014)... (PRWEB) September 29, 2014 Leading Conejo ... (PMIR) and Thousand Oaks Surgery Center (TOSC) –– are ... a state-of-the-art healthcare facility in Thousand Oaks, Calif. The ... practices that offer Conejo Valley residents greater access to ... and chronic pain, while TOSC physicians are setting the ...
(Date:9/29/2014)... The Pulmonary Hypertension Association ... Centers (PHCC) in a program that seeks to ... of patients with pulmonary hypertension (PH), specifically pulmonary arterial ... the lungs that affects the functioning of the heart ... mean survivability is only 2.8 years. , Despite medical ...
Breaking Medicine News(10 mins):Health News:National Association of Professional Women Announces Sarah Shiermeister, Clinical Manager Specialist at Gentiva Health Services, a 2014 Professional Woman of the Year 2Health News:Muscle Support and Style With New Compression Leg Sleeves For Cross Country Runners 2Health News:Chinese Regulations on In-Vitro Diagnostic Reagents Market: Application & Approval 2014 Edition New Study Now Available at MarketReportsOnline.com 2Health News:Chinese Regulations on In-Vitro Diagnostic Reagents Market: Application & Approval 2014 Edition New Study Now Available at MarketReportsOnline.com 3Health News:Chinese Regulations on In-Vitro Diagnostic Reagents Market: Application & Approval 2014 Edition New Study Now Available at MarketReportsOnline.com 4Health News:New Thousand Oaks Medical Facility Hosts Grand Opening Event: Two Practices, One Celebration 2Health News:New Thousand Oaks Medical Facility Hosts Grand Opening Event: Two Practices, One Celebration 3Health News:Pulmonary Hypertension Association Accredits First Six PH Care CentersApplication Process Now Open 2Health News:Pulmonary Hypertension Association Accredits First Six PH Care CentersApplication Process Now Open 3Health News:Pulmonary Hypertension Association Accredits First Six PH Care CentersApplication Process Now Open 4
... Academy of Family Physicians today announced the Consumer Alliance, ... partner, The Coca-Cola Company. , (Logo: ... program that allows corporate partners like The Coca-Cola Company ... the role their products can play in a healthy, ...
... CAMBRIDGE, Mass., Oct. 6 Galenea Corp., a fully-integrated ... been awarded an NIH Challenge Grant in Health and ... and Reinvestment Act of 2009 (Recovery Act). This ... addresses the specific topic of "Screening Approaches to Identify ...
... HOSPITAL ROOM , New research shows that certain noninvasive ... up to a distance of 1 m from patients ... spread of highly contagious respiratory illness within the hospital ... with mild lung injury, researchers from Hong Kong measured ...
... ... to earn continuing education credits , , ... Lincoln, NE (Vocus) October 5, 2009 -- The online ... Solutions (HES) recently received approval from the American Academy of Family Physicians (AAFP). The ...
... Speaker Nancy Pelosi issued the following statement congratulating molecular ... Francisco, who today was named to receive the 2009 Nobel ... W. Greider of Johns Hopkins University School of Medicine and ... of an enzyme that plays a key role in normal ...
... Superhero, to Feature DJ Cut Chemist, Violinist Lili Haydn, The ... Choir, The Raretones and Bells of the Sound , ... Symphony Guild today announced the artist lineup ... annual event which benefits Seattle Children,s Hospital ...
Cached Medicine News:Health News:The American Academy of Family Physicians Launches Consumer Alliance With First Partner: The Coca-Cola Company 2Health News:The American Academy of Family Physicians Launches Consumer Alliance With First Partner: The Coca-Cola Company 3Health News:The American Academy of Family Physicians Launches Consumer Alliance With First Partner: The Coca-Cola Company 4Health News:Galenea Awarded RC1 Challenge Grant to Develop Predictive In Vivo Models of Cognition 2Health News:News briefs from the October issue of Chest 2Health News:Health Education Solutions' Advanced Cardiac Life Support Course Gains Approval from American Academy of Family Physicians 2Health News:The Symphony Guild Announces Artist Lineup for 2009 Event 2Health News:The Symphony Guild Announces Artist Lineup for 2009 Event 3
(Date:9/29/2014)... -- Novogen Ltd. (ASX: NRT, NASDAQ: NVGN ) ... interview with ABC TV that was broadcast on Saturday September ... the following day on Weekend Breakfast. The interview concerned the ... clinic in Australia for the treatment ... The interview provides certain new information and is being ...
(Date:9/29/2014)... , Sept. 29, 2014  Lpath, Inc. (NASDAQ: ... bioactive lipid-targeted therapeutics, announced today the closing of ... As previously disclosed, Lpath sold 3,605,042 registered shares ... unregistered shares of common stock in a registered ... per share-and-warrant-share combination.  The warrants have an exercise ...
(Date:9/29/2014)... Sept. 29, 2014 Avanir Pharmaceuticals, Inc. (NASDAQ: ... its previously announced public offering of 20,930,000 shares of ... underwriters, full exercise of their option to purchase additional ... per share, before underwriting discounts. J.P. Morgan, Deutsche Bank ... managers for the offering. Piper Jaffray and ...
Breaking Medicine Technology:ABC TV Interview Discusses the Potential of Trilexium(TM) to Treat Brain Cancer 2ABC TV Interview Discusses the Potential of Trilexium(TM) to Treat Brain Cancer 3Lpath, Inc. Announces Closing of $12.5 Million Registered Direct Offering 2Lpath, Inc. Announces Closing of $12.5 Million Registered Direct Offering 3Avanir Pharmaceuticals Announces Closing of Public Offering of Common Stock and Full Exercise of Underwriters' Option to Purchase Additional Shares 2Avanir Pharmaceuticals Announces Closing of Public Offering of Common Stock and Full Exercise of Underwriters' Option to Purchase Additional Shares 3
... Symmetry Medical Inc. (NYSE: SMA ), a leading ... and other medical markets, announced today that it has entered ... November 3, 2010.  The credit facility includes an "accordion feature" ... million. The credit facility has a term of five years. ...
... Nov. 3, 2010 Aethlon Medical, Inc. (OTC ... in developing therapeutic filtration devices to address infectious ... present tomorrow at the at the Singular Research ... Los Angeles. (Photo:   http://photos.prnewswire.com/prnh/20090325/LA88762LOGO-b ) ...
Cached Medicine Technology:Symmetry Medical Closes $200 Million Credit Facility 2Symmetry Medical Closes $200 Million Credit Facility 3Aethlon Medical to Present at the Singular Research Fifth Annual 'Best of the Uncovereds Conference' 2Aethlon Medical to Present at the Singular Research Fifth Annual 'Best of the Uncovereds Conference' 3Aethlon Medical to Present at the Singular Research Fifth Annual 'Best of the Uncovereds Conference' 4
The 6.5mm cannulated cancellous ACE SCFE Screw is specifically designed for the treatment of slipped capital femoral epiphysis. The ACE SCFE Screw simplifies insertion and facilitates removal....
Smith & Nephew offers a wide variety of cannulated screw products. Most screw sizes are available in both partially threaded and fully threaded versions. , ,All systems optimize implant strength with...
... Humeral Nail enables fixation of humeral shaft ... may be associated with antegrade nailing. , ... distal interlocking using a nail-mounted targeting device. ... with the patient in the prone position. ...
... leading medical technology company and a ... more than a decade, introduces a ... ACT Plus System is a microprocessor-controlled ... coagulation endpoints in whole blood, citrated ...
Medicine Products: