Navigation Links
Painkillers May Raise Risk of Dangerous Heart Flutter
Date:7/5/2011

TUESDAY, July 5 (HealthDay News) -- A new study finds that painkillers widely used to treat inflammation are associated with an increased risk of atrial fibrillation, a heart rhythm disorder connected with a raised risk of stroke, heart failure and death.

Previous research has linked non-steroidal anti-inflammatory drugs (NSAIDs) and newer anti-inflammatory medications known as cox-2 inhibitors to an increased risk for heart attacks and strokes, but this is the first study to link the painkillers with atrial fibrillation.

Danish researchers looked at 32,602 patients who had a first diagnosis of atrial fibrillation between 1999 and 2008. Each of those patients was compared with 10 age and gender-matched controls from the general population in Denmark.

The results showed that use of these medications was associated with an increased risk of atrial fibrillation. The link was strongest among new users of the drugs, with a 70 percent increased risk for cox-2 inhibitors and a 40 percent increase in risk for non-selective NSAIDs.

The increased risk is equal to about seven extra cases of atrial fibrillation per 1,000 new users of cox-2 inhibitors and about four extra cases per 1,000 new users of non-selective NSAIDs, according to the researchers at Aarhus University Hospital.

They also found that the risk when starting treatment with cox-2 inhibitors seemed highest in older people and patients with chronic kidney disease or rheumatoid arthritis.

"Our study thus adds evidence that atrial fibrillation or flutter need to be added to the cardiovascular risks under consideration when prescribing NSAIDs," the researchers concluded.

"There is evidence that these medicines affected the heart, but [we] did not have evidence that it affected the rhythm of the heart. This study sheds light on another problem that we did not know with these medicines," Dr. Furqan Tejani, director of advanced cardiovascular imaging at SUNY Downstate Medical Center in New York City, said in a statement.

The study is published online in the July 4 issue of the BMJ.

The drugs do, indeed, have a checkered history.

In 2004, the blockbuster cox-2 inhibitor called Vioxx was pulled from the market because of its link to an increased risk of heart attack. In 2007, the American Heart Association warned doctors about the risk of giving NSAIDs to heart patients and recommended that these patients receive only the lowest dose and take the drugs for the shortest possible time.

In addition, a study published in the July 2010 issue of Circulation: Cardiovascular Quality and Outcomes found that healthy people who take NSAIDs to relieve minor aches and pains may be at increased risk of death from heart problems.

And a review of existing research this year found that NSAIDs taken to treat inflammation can boost the risk of heart attack, stroke or death. The researchers said their finding from the analysis of 31 clinical trials of NSAIDs suggest that a patient's cardiovascular risk needs to be assessed before being prescribed NSAIDs. That study appeared in the January issue of the BMJ.

More information

The American Academy of Family Physicians has more about atrial fibrillation.

-- Robert Preidt

SOURCES: BMJ, news release, July 4, 2011; Furqan Tejani, M.D., director, advanced cardiovascular imaging, and associate professor, medicine, SUNY Downstate Medical Center, New York City


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Common painkillers linked to irregular heart rhythm
2. After Heart Attack, Certain Painkillers May Raise Risk for Recurrence
3. Many Consumers Dont Know Whats in Over-the-Counter Painkillers: Study
4. Errors put infants, children at risk for overdose of painkillers
5. Common Painkillers May Blunt Antidepressants
6. FDA Looks to Crack Down on Misuse of Opioid Painkillers
7. Patients on Higher Doses of Prescription Painkillers More Apt to Overdose
8. CDC Links Prescription Painkillers in Pregnancy to Birth Defects
9. Retired NFL Players More Likely to Take Painkillers
10. Retired NFL players misuse painkillers more than general population
11. FDA Lowers Amount of Acetaminophen Allowed in Prescription Painkillers
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Painkillers May Raise Risk of Dangerous Heart Flutter
(Date:6/25/2016)... ... June 25, 2016 , ... Experts from the American ... Annual Research Meeting June 26-28, 2016, at the Hynes Convention Center in Boston. ... including advance care planning, healthcare costs and patient and family engagement. , AIR ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. Omkar Marathe ... from the David Geffen School of Medicine at UCLA. He trained in Internal Medicine ... his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the ...
(Date:6/24/2016)... ... ... Those who have experienced traumatic events may suffer from a complex set ... drug or alcohol abuse, as a coping mechanism. To avoid this pain and suffering, ... traumatic event. , Trauma sufferers tend to feel a range of emotions, from depression, ...
(Date:6/24/2016)... ... 24, 2016 , ... Dr. Amanda Cheng, an orthodontist ... has extensive experience with all areas of orthodontics, including robotic Suresmile technology, ... , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It can be used ...
(Date:6/24/2016)... NY (PRWEB) , ... June 24, 2016 , ... ... Haute Living, is proud to recognize Dr. Barry M. Weintraub as a prominent ... “the most beautiful women in the world, and the most handsome men, look ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 2016 Dublin ... addition of the " Global Markets for Spectroscopy ... This report focuses on the ... review, including its applications in various applications. The report ... includes three main industries: pharmaceutical and biotechnology, food and ...
(Date:6/24/2016)... SAN CLEMENTE, Calif. , June 24, 2016 /PRNewswire/ ... pulmonary function testing company, is now able to perform sophisticated lung ... ndd Medical Technologies , Inc. Patients are ... labs.  Thanks to ndd,s EasyOne PRO ® , ARL patients like ... any needed testing done in the comfort of her own home. ...
(Date:6/24/2016)... Belgium , June 24, 2016 ... the appointment of Dr. Edward Futcher ... Non-Executive Director, effective June 23, 2016.Dr. Futcher was ... Nominations and Governance Committees.  As a non-executive member ... independent expertise and strategic counsel to VolitionRx in ...
Breaking Medicine Technology: