Navigation Links
Painkillers May Be Good for the Prostate
Date:6/20/2009

Yet medical experts stress that men shouldn't take them with just this in mind

SATURDAY, June 20 (HealthDay News) -- Taking over-the-counter painkillers such as aspirin and ibuprofen might help men avoid prostate problems.

But even so, medical experts are quick to caution men not to self-dose or to take more than the recommended amounts of these medications, because harmful side effects can result.

"Our data suggest if men are taking these [medications] for another problem, it might prevent urological problems as well," said Jennifer St. Sauver, an epidemiologist at the Mayo Clinic in Minnesota who led a study that found that men who took nonsteroidal anti-inflammatory drugs (NSAIDs) daily had a reduction of about 50 percent in enlargement of the prostate gland. The condition, called benign prostatic hyperplasia, affects many men after age 40.

The gland, about the size of a walnut, is below the bladder and surrounds the urine-carrying canal or urethra. The gland often enlarges in older men, making urination difficult.

But men in St. Sauver's study who took painkillers daily had more than a third fewer moderate to severe urinary problems than men who did not take daily painkillers.

Lower levels of prostate specific antigen (PSA) also seem to be a benefit experienced by men who take NSAIDs regularly. PSA is a biomarker in the bloodstream that is used to assess the risk of getting prostate cancer.

Dr. Eric A. Singer, chief resident in urology at the University of Rochester Medical Center in New York, led a team of researchers who found that regular use of NSAIDs yielded PSA levels 10 percent lower than in men who didn't use them. St. Sauver's study found lower PSA levels among NSAID users in her study as well.

Men taking acetaminophen also were included in Singer's study, and they had about the same reduction in PSA levels. But, because the number of men who took acetaminophen was low, the result was not great enough to be statistically significant, he explained.

Exactly how the medications seemingly prevent enlargement of the prostate and other problems isn't certain, St. Sauver and Singer agreed. But they speculated that the medication's anti-inflammatory action plays a major role.

However, men who take NSAIDs need to keep in mind that, if taken in excess, the drugs can cause kidney ailments and other problems, Singer warned. And too much acetaminophen has been associated with liver toxicity.

The U.S. Food and Drug Administration warns that extended use of NSAIDs can increase the chances of a fatal heart attack or stroke and also can cause ulcers or excessive bleeding in the stomach and intestines.

Because of such possibilities, "we are certainly not telling men to take NSAIDs to reduce PSA or prostate cancer risk," Singer said, despite the "good news" from the studies.

''Talk to your health-care provider about prostate health and prostate cancer screening," he advised, adding a reminder to "make sure your doctor knows what medications you are taking."

No one knows exactly why some men develop prostate cancer, and others don't. In the United States, though, almost 190,000 men are expected to be diagnosed with the disease this year, and about one in six will develop it at some point in their life, according to the American Cancer Society.

Age is the main risk factor for prostate cancer. U.S. government statistics show that the disease rarely occurs in men younger than 40 and most often strikes men older than 65.

To treat prostate cancer that has not spread beyond the gland, according to the Cancer Society, doctors most often recommend:

  • Prostatectomy, surgery to remove all or part of the prostate gland
  • Radiation, either via an external beam or implanted radioactive seeds
  • Watchful waiting, the term used to describe deferring treatment until there are signs that the cancer is progressing

And, as treatment and detection methods have improved, the survival rate for prostate cancer has been improving in the United States in recent decades, according to the National Cancer Institute.

More information

The U.S. Food and Drug Administration has more on prostate health.



SOURCES: Jennifer St. Sauver, Ph.D., epidemiologist, Mayo Clinic, Rochester, Minn.; Eric A. Singer, M.D., chief resident, urology, University of Rochester Medical Center, Rochester, N.Y.; Cancer; American Journal of Epidemiology; American Cancer Society; U.S. Food and Drug Administration; U.S. National Cancer Institute


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. FDA Adds New Label Warnings to Over-the-Counter Painkillers
2. Painkillers May Not Protect Against Dementia
3. Post-Op Painkillers Tied to Deaths After Spinal Fusion
4. FDA Warns Drug Makers to Stop Selling Unapproved Prescription Painkillers
5. Labels on OTC Painkillers Need Improvement
6. FDA Seeks Better Regulation of Painkillers
7. Painkillers Linked to Increase in Overdose Deaths
8. Study Sheds Light on Painkillers Heart Risk
9. Common painkillers lower levels of prostate cancer biomarker
10. Study shows doctors offices can help stem abuse of Oxycontin, other narcotic painkillers
11. Painkillers Boost Muscle Mass Among Weight-Training Elderly
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Painkillers May Be Good for the Prostate
(Date:6/25/2016)... , ... June 25, 2016 , ... Austin residents seeking ... American College of Mohs Surgery and to Dr. Russell Peckham for medical and surgical ... effective treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room , the ... Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. , “We ... new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of First Choice ...
(Date:6/25/2016)... ... ... On Friday, June 10, Van Mitchell, Secretary of the Maryland Department of Health and ... their exemplary accomplishments in worksite health promotion. , The Wellness at Work Awards took ... the BWI Marriott in Linthicum Heights. iHire was one of 42 businesses to receive ...
(Date:6/24/2016)... ... , ... Those who have experienced traumatic events may suffer from a complex ... as drug or alcohol abuse, as a coping mechanism. To avoid this pain and ... a traumatic event. , Trauma sufferers tend to feel a range of emotions, from ...
(Date:6/24/2016)... Dallas, Texas (PRWEB) , ... June 24, 2016 ... ... 12th International Conference and Scientific Sessions in Dallas that it will receive two ... Announcement of the grants came as PHA marked its 25th anniversary by recognizing ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 2016   Pulmatrix, Inc ., (NASDAQ: ... drugs, announced today that it was added to the ... its comprehensive set of U.S. and global equity indexes ... important milestone for Pulmatrix," said Chief Executive Officer ... our progress in developing drugs for crucial unmet medical ...
(Date:6/23/2016)...  MedSource announced today that it has selected ... of choice.  This latest decision demonstrates MedSource,s commitment ... clients by offering a state-of-the-art electronic data capture ... as the EDC platform of choice in exchange ... has long been a preferred EDC platform by ...
(Date:6/23/2016)... June 23, 2016 Research and ... Excipients Market by Type (Organic Chemical (Sugar, Petrochemical, Glycerin), ... Topical, Coating, Parenteral) - Global Forecast to 2021" ... The global pharmaceutical excipients market is projected ... CAGR of 6.1% in the forecast period 2016 to ...
Breaking Medicine Technology: