In conjunction, the participants were randomly divided into an acetaminophen group, an ibuprofen group or a placebo group.
The two drugs were consumed at recommended daily dosage levels, as noted on current over-the-counter packaging.
To the research team's surprise, an analysis of muscle tissue samples taken before and after revealed that while the placebo group experienced a 7 percent growth in muscle mass and strength, those taking either acetaminophen or ibuprofen experienced an even greater gain -- 40 percent to 60 percent more.
Trappe theorized that the two drugs could be provoking the body to overcompensate for an initial blocking of the enzyme any muscle needs to grow -- prompting muscles to send out fresh and powerful signals demanding even more enzyme than the body would normally produce.
"But as of now, we just don't know," Trappe said. And he cautioned against anyone running out to down over-the-counter drugs of any kind before further research is conducted.
In the meantime, David Bassett Jr., a professor of exercise science at the University of Tennessee in Knoxville, hailed the reputation of the physiology lab that conducted the research and described the finding as "within the realm of believability."
"A 7 percent increase in strength and mass based on resistance training alone doesn't strike me as that great of a gain, relative to other similar studies," he noted. "But I do think it is a new and pretty significant finding that these two drugs would bring about a greater increase than otherwise."
"It's important," Bassett added, "because some even make the case that resistance training among the elderly is almost more important than aerobic training, because weight training can significantly improve functional strength and the ability to carry out the activities of daily independent living."
However, Bassett pointed out that despite the apparent absence of s
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