Navigation Links
Painkiller May Prevent Diabetes-Related Retinal Damage
Date:9/24/2008

Pentazocine's effects on eye health called 'phenomenal,' study concludes

WEDNESDAY, Sept. 24 (HealthDay News) -- The painkiller pentazocine may help prevent diabetes-related retinal damage that leads to vision loss, according to Medical College of Georgia researchers.

"The effects of this drug on retinal health are phenomenal," Dr. Sylvia Smith, a retinal cell biologist and co-director of the Vision Discovery Institute at MCG's School of Medicine, said in a college news release.

For the study, she compared the retinas of diabetic mice treated with pentazocine and those that didn't receive the drug and found dramatic differences. The findings suggest that the drug and related compounds that bind with the sigma receptor in the eye may help treat the two leading causes of vision loss -- diabetic retinopathy and glaucoma.

The study was published in the September issue of the journal Investigative Ophthalmology & Visual Science.

Pentazocine's binding with sigma receptors didn't affect insulin levels in the diabetic mice.

"(The drug) does not solve that problem of diabetes; however, our findings do suggest that just because you are hyperglycemic does not mean you will have diabetic retinopathy," Smith said.

She and her team are collaborating with other MCG researchers to breed mice without a sigma receptor to learn more about the receptor's role and whether regular treatment with pentazocine will prove effective in mice with other types of retinal disease.

More information

The American Diabetes Association has more about diabetes-related eye complications.



-- Robert Preidt



SOURCE: Medical College of Georgia, news release, Sept. 9, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Office-Based Medical Treatment and Internet Resources Are Potential Solution to Rising Painkiller Misuse Among Teens, Young Adults
2. Why dont painkillers work for people with fibromyalgia?
3. Antidepressants and painkillers - a dangerous combination
4. Morphine Painkillers Wont Impair Driving
5. Acupuncture Cuts Need for Post-Op Painkillers
6. Vioxx Settlement Puts Painkillers Back in the Spotlight
7. Minorities Less Likely to Get Powerful Painkillers in ER
8. NSAIDs: Painkillers, inflammation inhibitors, anti-cancer drugs and new de-methylating agents
9. Painkillers Boost Muscle Mass Among Weight-Training Elderly
10. User Registry May Help Docs Stem Painkiller Abuse
11. Study shows doctors offices can help stem abuse of Oxycontin, other narcotic painkillers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/27/2017)... Eau Claire, WI (PRWEB) , ... March 27, ... ... currently accepting new patients for custom smile makeovers without requiring a ... needs including orthodontics, gum disease treatment, cosmetic dentistry and dental implants. Whether patients ...
(Date:3/27/2017)... and London UK (PRWEB) , ... March 27, ... ... speed, agility and ability to gain site attention and engagement over the household ... educational webinar will discuss how partnering with the right outsourcing ...
(Date:3/27/2017)... ... March 27, 2017 , ... ... it will co-exhibit with technology partners LG Business Solutions at ATARC Federal ... Center in Washington D.C., will provide education and examination into the mobility tools ...
(Date:3/27/2017)... ... March 27, 2017 , ... M&S Technologies, the first ... for the Smart System® 20/20. CE Certification builds upon M&S's long-standing commitment to ... such as ANSI, ISO and proven test methods used in the field of ...
(Date:3/27/2017)... ... March 27, 2017 , ... Osteitis pubis may be commonplace ... injury, it occurs when the muscles around the pelvis become inflamed. Over time, ... lower torso, as well as accompanying tenderness and weakness. Without proper intervention, it ...
Breaking Medicine News(10 mins):
(Date:3/27/2017)... March 27, 2017 The National University ... and data analytics company, signed a Memorandum of ... healthcare delivery in the region. ... Health Research and Technology (BIGHEART) at NUS and ... topics related to healthcare IT and medical device ...
(Date:3/27/2017)... , March 27, 2017  ImMAGE Biotherapeutics (OTCMKTS: IMMG), ... successfully passed early toxicology and efficacy studies. The company ... target a specific protein, MAGE A, in an effort ... cancer. After 4 weeks of treatment ... show very little toxicity in a full toxicology report ...
(Date:3/27/2017)... 27, 2017  Sanderling Ventures, portfolio company, Torax ... division of Johnson & Johnson. Torax manufactures and markets ... of gastro-esophageal reflux disease (GERD). The LINK device ... and the procedure is currently available in the ... Medical was founded by Sanderling Ventures, Mayo Medical ...
Breaking Medicine Technology: