Navigation Links
Pain-free microneedle influenza vaccine is effective, long-lasting
Date:9/4/2013

Scientists have developed an influenza vaccine delivered via microneedle patch that provided 100 percent protection against a lethal influenza virus in mice more than one year after vaccination. They report their findings in the September 2013 issue of the journal Clinical and Vaccine Immunology.

Microneedles are a medium for delivery of influenza vaccine that avoids the pain associated with ordinary hypodermic needles. They are a mere seven tenths of a millimeter in length, and the volume of vaccinea major contributor to painis minuscule.

Instead of a liquid containing whole killed or attenuated virus, this vaccine uses dry virus-like particles (VLPs) which simply coat the needles in the presence of a simple stabilizing agent, reducing the need for refrigeration a potential boon for use in developing countries. The lower dose required when using microneedles also reduces the potential for side effects, such as lung inflammation.

"This method can induce higher levels of IgG2a antibodies as well as rapid recall immune responses following lethal challenge infection. Our previous study showed that microneedle vaccination induced higher levels of antibody-secreting cells in spleen and bone marrow compared to intramuscular vaccination," says Sang-Moo Kang of Georgia State University, a researcher on the study.

Earlier studies by this group showed that influenza VLP-coated microneedles actually produced higher short-term protection than conventional intramuscular immunization. In this study the researchers tested how effective the long-term protection of the vaccine was. Mice that received the vaccine were 100 percent protected from a lethal challenge with the influenza virus 14 months after vaccination.

Kang says his aim was to develop an easier and pain-free method of vaccine delivery. He also says that patients could probably use this system to vaccinate themselves.


'/>"/>

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
Source:Eurekalert

Page: 1

Related medicine news :

1. Highlands Ranch, CO Cosmetic Dentist Dr. Michael R. Varley Introduces Treatment for Pain-Free Dentistry
2. Queens Dentist Now Offers DentalVibe to Make Dental Implants Pain-Free
3. Dr. Doron Keren, Port Washington Dentist, Introduces New Pain-Free Dental Cleaning Technology
4. With the Launch of Dr-Pain.com, the Become Pain-free Doctor Network Continues Expansion with Top Pain Management Doctors and Spine Surgeons
5. Measles vaccine given with a microneedle patch could boost immunization programs
6. Research shows potential of microneedles to target therapeutics to the back of the eye
7. NIH-funded scientists describe genesis, evolution of H7N9 influenza virus
8. Joint Study Sheds New Light on the Cause of Pandemic Influenza
9. Behavior change may have the greatest influence on waves of influenza outbreak: McMaster study
10. New study describes imaging findings in H7N9 influenza
11. Ferrets, pigs susceptible to H7N9 avian influenza virus
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... Clarity PSO , an operating division of ... Patient Safety Organization (PSO) for another three-year period under ... Quality (AHRQ). Clarity PSO will continue to provide valuable ... true intentions of the Patient Safety and Quality Improvement ... eager to continue our journey as a PSO and ...
(Date:8/28/2014)... San Franisco, CA (PRWEB) August 28, 2014 ... emerging marijuana business sector recently launched a “Video” ... relevant news and general information on various cannabis ... section, individuals can find an assortment of news ... marijuana-related issues and announcements. A portion of the ...
(Date:8/28/2014)... PreDiabetes Centers, the nation’s top provider of ... to help clients and online readers send out summer ... Han Ashley developed variations of Roasted Veggie Pizza ... The PreDiabetes Centers Roasted Veggie Pizza recipe is made ... features a cheese substitute–ideal for people who are lactose ...
(Date:8/28/2014)... (PRWEB) August 28, 2014 Vitals, a recognized ... Dr. Sabrina Fabi of Cosmetic Laser Dermatology one of their ... of thousands of patients to share their doctor experiences and ... manner, face time, and follow-ups. The Vitals Top 10 Doctor ... Dr. Fabi was ranked one of the highest by patients. ...
(Date:8/28/2014)... 28, 2014 It is not uncommon for ... unsuccessful dieting attempts. Many face ridicule and judgment and find ... thoughts and feelings, wondering why they keep gaining weight and ... solace in comfort foods, eating more and gaining more, leaving ... , Diet Doc has helped thousands safely, successfully and ...
Breaking Medicine News(10 mins):Health News:Clarity PSO Re-lists as a Patient Safety Organization and Continues to Advance Patient Safety 2Health News:Clarity PSO Re-lists as a Patient Safety Organization and Continues to Advance Patient Safety 3Health News:Emerging Cannabis Industry Website GreenRushReview.com Adds a Featured Video Section to Cover Marijuana Business Sector News 2Health News:Emerging Cannabis Industry Website GreenRushReview.com Adds a Featured Video Section to Cover Marijuana Business Sector News 3Health News:PreDiabetes Centers Concierge Chef Creates Tasty Grilled Veggie Pizza Recipes for Labor Day Party Menu 2Health News:PreDiabetes Centers Concierge Chef Creates Tasty Grilled Veggie Pizza Recipes for Labor Day Party Menu 3Health News:Dr. Sabrina Fabi of Cosmetic Laser Dermatology Recognized as Vitals Top 10 Doctor 2Health News:Diet Doc’s Medical Weight Loss Programs Announce New Help for Patients Who Want to Overcome Depression Caused by Excess Weight 2Health News:Diet Doc’s Medical Weight Loss Programs Announce New Help for Patients Who Want to Overcome Depression Caused by Excess Weight 3
... Offers Hope to Millions of Couples Seeking a Better Sex,Life, ... relieved by the,preliminary results of a new study that demonstrates ... lives. The exercises take,just 5 minutes a day but the ... who followed the simple PelvicToner exercise,programme reported an improved sex ...
... to farms, particularly to barns and farm milk, while ... to a group of German researchers, who will present ... Conference in Toronto on Wednesday, May 21., In a ... 59 non-farming mothers, the researchers believe they have proved ...
... their Prescription History, WALNUT CREEK, Calif., May ... ) announced today a new collaboration with,Google Health ... between,patients and providers. Working with Google, Longs will ... customers with the ability to import their,prescription information ...
... 18, 2008 TAP Pharmaceutical Products Inc. today reported ... new drug TAK-390MR, the first proton pump inhibitor (PPI) ... patients with erosive esophagitis (EE) and in maintenance of ... Disease Week (DDW) annual meeting in San Diego. , ...
... over T-cell counts for monitoring HIV treatment , ... can help identify those whose treatment will succeed or ... from pharmacy records, works at least as well as ... the immune system, according to research published in PLoS ...
... initiation and progression of prostate cancer have eluded ... researchers have identified a specific gene expression profile ... for future treatments. The findings, published in BioMed ... genes that are differentially expressed in certain prostate ...
Cached Medicine News:Health News:Is Female Sexual Dysfunction a Myth? 2Health News:Farm moms may help children beat allergies 2Health News:Longs Drugs Partners With Google on the Launch of Google Health 2Health News:TAK-390MR Phase 3 data presented at Digestive Disease Week 2Health News:TAK-390MR Phase 3 data presented at Digestive Disease Week 3Health News:TAK-390MR Phase 3 data presented at Digestive Disease Week 4Health News:Monitoring whether patients take medicines can help anticipate HIV treatment failure in Africa 2Health News:Monitoring whether patients take medicines can help anticipate HIV treatment failure in Africa 3Health News:Monitoring whether patients take medicines can help anticipate HIV treatment failure in Africa 4Health News:Monitoring whether patients take medicines can help anticipate HIV treatment failure in Africa 5Health News:Mapping of prostate cancer genes opens the door to new treatments 2
(Date:8/28/2014)... 28, 2014 The Leukemia & Lymphoma ... to advance an experimental cancer vaccine to treat ... stage of myeloma. The partnership is ... LLS forges collaborations with biotechnology companies to help ... OncoPep is developing a vaccine, PVX-410, designed to ...
(Date:8/28/2014)... Calif. , Aug. 28, 2014  STAAR Surgical Company ... marketer of implantable lenses and delivery systems for the eye, ... Health Care Conference at the New York Palace Hotel on ... Barry Caldwell , President and CEO will offer ... results, and operational developments and be joined by Steve ...
(Date:8/27/2014)... Aug. 28, 2014 China Nepstar Chain ... the "Company"), a leading retail drugstore chain in ... stores, today announced its unaudited financial results for ... Financial HighlightsFor the quarter ended June 30, 2014: ... million) compared to RMB638.8 million in the second ...
Breaking Medicine Technology:The Leukemia & Lymphoma Society Provides Equity Financing to OncoPep to Support Clinical Trial for Myeloma Vaccine 2STAAR Surgical To Present At The Baird 2014 Health Care Conference 2China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 2China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 3China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 4China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 5China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 6China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 7China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 8China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 9China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 10China Nepstar Chain Drugstore Ltd. Reports Second Quarter 2014 Financial Results 11
... goBalto , developer of new generation web-based clinical research solutions, ... Tufts Center for the Study of Drug Development ... there is virtually no industry data available on the typical ... that this process takes. Tufts CSDD, an independent, ...
... 2011 Solos Endoscopy, Inc. (OTCPK: SNDY) is pleased ... growth in the multi-billion dollar endoscopic market.  Solos Endoscopy ... Clinics, Healthcare Centers, Medical Centers and Surgery Centers across ... instrument internationally upon receiving the CE Mark. ...
Cached Medicine Technology:goBalto Sponsors Tufts CSDD Study to Benchmark the Clinical Trial Initiation Process 2Solos Endoscopy Poised for Tremendous Growth in Multi-Billion Dollar Endoscopic Market 2
... Series refrigerators from Taylor-Wharton are uniquely designed ... convenient box-type storage racks and the lower ... storage. The RackSystems are available in four ... from 750 x 2ml vials to 4800 ...
... chairs with concave seats and standard-sized ... options like seats, backrests, armrests, and ... are recommended for the following environments: ... control, health care and office. • ...
... with concave seats and standard-sized backrests ... like seats, backrests, armrests, and casters ... recommended for the following environments: industry, ... health care and office. • With ...
... Basic ergonomic chairs with concave ... support • Select options like seats, ... • BTP/1Q-PAL chairs are recommended for ... clean room, static control, health care ...
Medicine Products: