Navigation Links
Pain, pain, go away
Date:5/20/2013

University of Texas Medical Branch at Galveston researchers have been awarded a five-year, $1.8 million grant by the National Institute of Neurological Disorders and Stroke to apply the techniques of gene therapy to the problem of neuropathic pain that is, pain that arises from a malfunction in the nervous system.

Neuropathic pain is a daily reality for millions of Americans, manifesting itself in a variety of life-impairing ways. Someone suffering from neuropathic pain might feel intense discomfort in response to a light touch, for example, or suddenly feel as though he or she were freezing in response to a small decrease in temperature. Caused by either accidental or disease-induced nerve damage, this kind of pain has proven very difficult to treat.

"Patients in neuropathic pain are willing to do almost anything to get relief," said Dr. Volker Neugebauer, the co-principal investigator on the grant. "They're in torment, often in really desperate situations."

To make matters worse, long-term neuropathic pain often causes depression, acting through emotional mechanisms in the brain meant to underscore the importance of pain signals. Depression further increases the perception of pain, creating a vicious cycle of increasing pain and depression. And while conventional pain medicines can block the pain signal, they are usually successful for only a limited time only; eventually the pain returns when the nervous system compensates for the blockade.

Neugebauer and his UTMB colleague and co-principal investigator Thomas Green believe that a better anti-neuropathic pain strategy is to target higher brain regions and prevent the abnormal generation of persistent emotions. They focus on the amygdala, a structure best known for its role in emotional responses, including anxiety and depression and in Neugebauer's previous work for its connection to pain regulation. Neugebauer and Green hypothesize that stopping abnormal activity in
'/>"/>

Contact: Jim Kelly
jpkelly@utmb.edu
409-772-8791
University of Texas Medical Branch at Galveston
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Study suggests touch therapy helps reduce pain, nausea in cancer patients
2. Docs Make Push to Lower Kids Pain, Stress in ER
3. Caddy Products, LLC, Makers of FaceCaddy Therapeutic Ice and Heat Wrap, Launches EyesCaddy and BackCaddy to Address Sinus Pain, Migraines and Back Pain.
4. Women’s Excellence in Endometriosis Presents a New State-of-the-Art Center for Pelvic Pain, Painful Intercourse, and Painful Periods in Lake Orion, MI
5. New Book The MELT Method Offers a Breakthrough Self-Treatment System to Eliminate Chronic Pain, Erase the Signs of Aging, and Feel Fantastic in Just 10 Minutes a Day!
6. Zion Health Announces Release of New Line of Home Remedies: Kanwa Whole Body Detox teas for Stomach Pain, Ulcers, and Skin Allergies Now available at Bee Health E in Doug
7. Kent Chiropractor, Dr Paul Byers, Discusses His Soon To Be Released Book, Chiropractic Cures for Neck and Back Pain, Educating Patients 253-852-1250 http://www.byerschiro.com
8. Battle for Grace: A Memoir of Pain, Redemption and Impossible Love
9. Affordable Acupuncture Practice Helps South Florida Residents Relieve Pain, Sleep Better, Reduce Stress and More
10. Copper Magnetic Bracelet Relieves Pain, Announced Pain Free Living
11. Molecular Diagnostics Market - US, UK, Spain, Japan, Italy, Germany & France Analysis in New Research Report at ReportsnReports.com
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/27/2015)... Attorney Dan Newlin, of the Law Offices ... clients, took that commitment to a whole new level with ... it easier for existing and potential clients to contact the ... and added value to the firm’s services, #Dan covers Central ... has law offices. , “I knew the pound sign (#) ...
(Date:4/27/2015)... 27, 2015 Texas has saved $433 ... drug offenders to providing drug offenders with addiction treatment, ... on April 8th. Several states, including Massachusetts, are considering ... incarceration. Texas has formed community recovery programs to help ... The Council of State Governments WA, ID, NE, ...
(Date:4/27/2015)... 2015 Climate change predictions are largely ... the number of variables used and the availability of ... water researcher Gerald Pollack, PhD, and Climatologist L.DeWayne Cecil, ... Water® radio show, noted three potential weaknesses that could ... of these individuals dispute that Earth’s climate is changing. ...
(Date:4/27/2015)... Winscribe Professional for Windows Phones ... mobile speech productivity technology, which also includes applications ... , Winscribe has supported mobile dictation ... With the latest enhancement, Winscribe Professional for ... interface in the last ten years. The ...
(Date:4/27/2015)... PREVENT Life Safety, America’s premier provider ... with the addition of an account manager in Houston. ... a growing customer base, Curtis Rice, an experienced sales ... Account Manager. Curtis has been added to the team ... the Houston area and beyond. , Curtis ...
Breaking Medicine News(10 mins):Health News:Dan Newlin Hashtags It With #Dan 2Health News:Texas Saves $443 Million Embracing Justice Reinvestment for Drug Charges 2Health News:Texas Saves $443 Million Embracing Justice Reinvestment for Drug Charges 3Health News:Global warming: Computer weather models flawed report Climatologist, Water Researcher on Sharon Kleyne Hour™ radio show 2Health News:Global warming: Computer weather models flawed report Climatologist, Water Researcher on Sharon Kleyne Hour™ radio show 3Health News:Winscribe Professional Dictation for Smartphones Evolves as Microsoft’s Mobile OS Grows 2Health News:Winscribe Professional Dictation for Smartphones Evolves as Microsoft’s Mobile OS Grows 3Health News:Winscribe Professional Dictation for Smartphones Evolves as Microsoft’s Mobile OS Grows 4Health News:PREVENT Life Safety Services Welcomes Curtis Rice as a New Senior Account Manager in Houston, TX 2
... Bangalore, SUNNYVALE, Calif., Jan. 8 Accuray,Incorporated ... the field of radiosurgery,announced today that Healthcare Global ... for its new oncology center in,Bangalore, India. Upon ... first,CyberKnife System in India, expanding treatment access to ...
... N.J., Jan. 8 Jennifer J. Day, Senior Vice,President ... the,addition of Kenneth A. Sylvia as publisher of Current ... healthcare industry who brings to DHM,30 years of experience ... bases we serve," Day said. DHM is a subsidiary ...
... Affairs highlights large employer,s efforts to ... to treatment, PHILADELPHIA, Jan. 8 Removing ... to remain,on recommended therapies according to a new ... Health Affairs. The study, funded, in part,by GlaxoSmithKline ...
... Too Faced ... Cosmetics and FUZE Beverages, NEW YORK, Jan. 8 ... a lip gloss that keeps you both energized,and beautiful. Yes indeed ... lip gloss on the market to "fuse" beauty and fitness,benefits, this ...
... Centers and free coffee ... give blood, DETROIT, Jan. 8 In honor of ... Cross Donors,Employees and Volunteers in Michigan for two weeks in ... all donors,at any of the participating American Red Cross blood ...
... Medicaid spending slowed for first time since its inception ... The new Medicare prescription drug plan was largely responsible ... 2006, which was double the increase in spending from ... 2006, Medicare spending reached $401.3 billion, an increase from ...
Cached Medicine News:Health News:CyberKnife Radiosurgery Expands to India 2Health News:CyberKnife Radiosurgery Expands to India 3Health News:New Study Indicates Decreasing Prescription Copayments Results in Increased Adherence for Patients with Chronic Diseases 2Health News:New Study Indicates Decreasing Prescription Copayments Results in Increased Adherence for Patients with Chronic Diseases 3Health News:New Study Indicates Decreasing Prescription Copayments Results in Increased Adherence for Patients with Chronic Diseases 4Health News:New Study Indicates Decreasing Prescription Copayments Results in Increased Adherence for Patients with Chronic Diseases 5Health News:NEW! Too Faced FUZE Slenderize Guilt Free Gloss 2Health News:Dunkin' Donuts Celebrates the New Year by Supplying Goodies to Michigan's American Red Cross 2Health News:Medicare Drug Plan Fuels Health-Care Spending 2Health News:Medicare Drug Plan Fuels Health-Care Spending 3
(Date:4/27/2015)... JERUSALEM , April 27, 2015 ... successfully completed filing of a Pre-Marketing Notification Application (510k) ... its BRH-A2 Wound Management System. BRH Medical expects feedback ... entering the US market with BRH-A2 following FDA pre-market ... Motti Oderberg , CEO for BRH ...
(Date:4/27/2015)... , April 27, 2015 - ... Process Patent by the State Intellectual Property Office of ... Based on Pooling Technology  - A New Treatment ... (CLI)    - About 20% of Elderly Urban ... in Women is Substantially Higher Than in Men. CLI is ...
(Date:4/26/2015)... April 26, 2015  Ikonopedia announced today that ... system have been selected for use by BelleBridge, ... screening and diagnostic examinations. Ikonopedia will showcase its ... of Breast Imaging,s SBI/ACR Breast Imaging Symposium in ... 2015 (SBI Booth #216). BelleBridge is ...
Breaking Medicine Technology:BRH Medical, Ltd., Announces Filing of a Pre-Market Submission with the US Food and Drug Administration (FDA) for the BRH-A2 Tissue Management System 2Stempeutics Gets Stem Cell Patent in China (Chinese Application Number: CN201080053627) for its Novel Stem Cell Drug 'Stempeucel' 2Stempeutics Gets Stem Cell Patent in China (Chinese Application Number: CN201080053627) for its Novel Stem Cell Drug 'Stempeucel' 3Stempeutics Gets Stem Cell Patent in China (Chinese Application Number: CN201080053627) for its Novel Stem Cell Drug 'Stempeucel' 4Ikonopedia Selected to Provide Breast Imaging Report Generation Capabilities for BelleBridge's Breast Telemedicine Services 2Ikonopedia Selected to Provide Breast Imaging Report Generation Capabilities for BelleBridge's Breast Telemedicine Services 3Ikonopedia Selected to Provide Breast Imaging Report Generation Capabilities for BelleBridge's Breast Telemedicine Services 4
... of human-animal hybrids to generate stem cells WORCESTER, ... Pink Sheets: ACTC) and its collaborators reported today that ... reprogram adult human cells. The research, which appears online ... Stem Cells (Editor-in-Chief: Sir Ian Wilmut; published by ...
... Men who experience erectile dysfunction between the ages of ... disease than men without dysfunction, according to a new Mayo ... have an 80 percent higher risk of heart disease. "The ... says researcher Jennifer St. Sauver, Ph.D. The study was published ...
Cached Medicine Technology:Cloned Human Embryos Successfully Reprogrammed Using Human - But Not Animal - Eggs 2Cloned Human Embryos Successfully Reprogrammed Using Human - But Not Animal - Eggs 3Cloned Human Embryos Successfully Reprogrammed Using Human - But Not Animal - Eggs 4Cloned Human Embryos Successfully Reprogrammed Using Human - But Not Animal - Eggs 5Mayo Clinic Study Finds Younger Men With Erectile Dysfunction at Double Risk of Heart Disease 2Mayo Clinic Study Finds Younger Men With Erectile Dysfunction at Double Risk of Heart Disease 3
Micro instruments designed to provide maximum grasping, resecting capability, and excellent maneuverability for easy access to tight, small joints (wrist, elbow, and ankle).,Features pinless hinge d...
... LactoSorb® No-Profile Screw and Washer ... for multiple soft tissue re-attachments ... No-Profile Screw and washer provides ... a standard screw and washer ...
... The Stryker Inter-Lock™ System ... surgery at the tibial fixation ... backup fixation into one implant. ... and can be used routinely ...
The Stryker Bioabsorbable Wedge Interference Screw is made of Poly-L Lactic Acid (PLLA). The patented wedge design makes it perfect for cruciate reconstruction and is indicated for BTB and soft tissu...
Medicine Products: