Navigation Links
Pace of New Drug Advances May Be Slowing, Study Finds
Date:6/4/2013

By Amy Norton
HealthDay Reporter

TUESDAY, June 4 (HealthDay News) -- The drugs emerging from clinical trials in recent years seem less impressive than those developed in decades gone by, a new review finds.

Looking at more than 300 studies done since 1966, researchers found that drugs under development these days are less likely to solidly outperform placebos -- the sugar pills or other inert substances against which new drugs are tested.

From 1966 to 1990, the average study drug was about four times as likely to achieve a particular outcome than a placebo. But in trials done since 2001, drugs were only 36 percent more likely than placebos to show a desired effect, researchers reported in the June issue of the journal Health Affairs.

The reasons for the "worrisome decline" are not clear, said lead researcher Dr. Mark Olfson, a professor of clinical psychiatry at Columbia University in New York City.

But it's possible, he said, that "much of the low-hanging fruit has already been picked. In other words, many of the easiest-to-discover effective treatments may have already been found."

Another possibility, though, is that drugs from days of yore were not as impressive as they seemed at the time.

Trials done today generally have a more rigorous design, and they may be producing fewer "spuriously inflated findings" compared to older clinical trials, Olfson said.

A researcher not involved in the work said the findings are interesting, but "raise more questions than answers."

"The study is not designed to tell us the causes," said Ted Kaptchuk, an associate professor of medicine at Harvard Medical School, and director of the university's program in placebo studies.

"Are the new drugs in the pipeline just not as good?" Kaptchuk asked. It's not clear. In part, he said, that's because other research has found that people in clinical trials these days are more likely to respond t
'/>"/>

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. NJ stroke researchers report advances in spatial neglect research at AAN Conference
2. NYU Langone experts present research, clinical advances at neurosurgeons meeting
3. Triple negative breast cancer symposium highlights current advances
4. Studies See Advances in Detecting, Treating Pancreatic Cancer
5. Hi-Tech Advances May Improve Diabetics Lives
6. Meeting in Jordan to educate medical professionals on latest advances in osteoporosis
7. Advances in ataxia research to be featured at USFs Innovative Learning and Simulation Center
8. Key research from the 2012 Breast Cancer Symposium highlights treatment advances for early breast cancer
9. Collegiate inventors honored for innovative science and technology advances
10. Research from ASCOS Quality Care Symposium shows advances and challenges in improving the quality of cancer care
11. USC Norris cancer research ranks among top clinical advances for 2012
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Pace of New Drug Advances May Be Slowing, Study Finds
(Date:7/25/2014)... IL (PRWEB) July 25, 2014 Progress ... ushered in a new era of promising brain tumor ... Harvard Medical School, director of the Center for Neuro-Oncology, ... Association (ABTA) annual Patient and Family Conference in Chicago, ... how science and new technology are impacting the development ...
(Date:7/25/2014)... According to the new report "Sapphire ... and Geography - Analysis & Forecast to 2013 - ... to reach $3.01 Billion by 2020 at a CAGR ... devices is expected to reach $6.17 billion by 2020 ... analysis of application and geography. , Browse more than ...
(Date:7/25/2014)... Jose, CA (PRWEB) July 25, 2014 ... MaaS360 WorkPlace Partner Program . Splashtop Business and Splashtop ... Market, and will leverage the MaaS360 WorkPlace SDK ... data. , Splashtop Business and Splashtop Enterprise offer secure ... any device. High performance, ease of use, ...
(Date:7/25/2014)... Agoura Hills dentist , Dr. Amir ... Zoom Whitening is one of the most powerful whitening treatments ... professional. This light-assisted treatment uses a prescription-strength gel that can ... to break up stains that are in both the enamel ... soft drink and tobacco stains. , About Dr. Amir ...
(Date:7/25/2014)... IL (PRWEB) July 25, 2014 Garth Brooks ... performance at the Allstate Arena in Rosemont. Garth Brooks was ... time he released his first single in 1989. Since "Much Too ... flocked to the shows from the Tulsa, Okl. native and in ... wanted to see him back on a stage and in the ...
Breaking Medicine News(10 mins):Health News:Immunotherapy, Targeted Molecular Therapies Among Promising New Treatments for Brain Tumors 2Health News:Immunotherapy, Targeted Molecular Therapies Among Promising New Treatments for Brain Tumors 3Health News:Immunotherapy, Targeted Molecular Therapies Among Promising New Treatments for Brain Tumors 4Health News:Sapphire Technology Market Estimated to Reach $3.01 Billion by 2020 – New Report by MarketsandMarkets 2Health News:Sapphire Technology Market Estimated to Reach $3.01 Billion by 2020 – New Report by MarketsandMarkets 3Health News:Sapphire Technology Market Estimated to Reach $3.01 Billion by 2020 – New Report by MarketsandMarkets 4Health News:Sapphire Technology Market Estimated to Reach $3.01 Billion by 2020 – New Report by MarketsandMarkets 5Health News:Sapphire Technology Market Estimated to Reach $3.01 Billion by 2020 – New Report by MarketsandMarkets 6Health News:Splashtop Joins the MaaS360 WorkPlace Partner Program 2Health News:Splashtop Joins the MaaS360 WorkPlace Partner Program 3Health News:Splashtop Joins the MaaS360 WorkPlace Partner Program 4Health News:Agoura Hills Dentist, Dr. Amir Choroomi, is Now Offering a Promotion on Zoom Whitening 2Health News:Garth Brooks Chicago Tickets for Performance at Allstate Arena in Rosemont Go On Sale July 25th 2Health News:Garth Brooks Chicago Tickets for Performance at Allstate Arena in Rosemont Go On Sale July 25th 3
... Artery-opening procedure can be done up to 21 hours later ... (HealthDay News) -- Many people who arrive at hospital emergency ... hours for artery-opening angioplasty, even if an electrocardiogram (EKG) shows ... , There was no significant difference in key measures of ...
... , , CARDIFF, Calif., Sept. 1 ... ( http://www.jedimindinc.com ) announced today that their Medical ... for patients in wheelchairs. An estimated 1.6 million Americans residing ... National Health Interview Survey on Disability (NHIS-D). Jedi Mind,s Medical ...
... , , ATLANTA, Sept. 1 ... 50 schools across the U.S. with $2,000 ... ING Run For Something Better School Awards Program, financial ... for Sport and Physical Education (NASPE), is helping to ...
... Less invasive procedure shaves off lesions, researchers say , ... the esophagus can be treated effectively by less invasive, ... This is good news, as esophageal cancer arising from ... other cancer in the United States, and 90 percent ...
... Angeles, London, New Delhi, Singapore and Washington DC (1 ... and professional publisher is delighted to announce a new ... their official journal, Cephalalgia . Now in ... forum for original research papers, review articles and short ...
... available in French . , Montreal, ... autoimmune disorders which cause muscular inflammation are at increased ... Montreal researchers. Dr. Christian A. Pineau and his team ... Centre (RI-MUHC) have linked muscular inflammation to increased cardiovascular ...
Cached Medicine News:Health News:Sometimes Angioplasty Can Wait 2Health News:Jedi Mind Medical Applications Division to Concentrate on Wheelchair Mobility Applications 2Health News:ING Awards $100,000 in Grants to Combat Childhood Obesity 2Health News:ING Awards $100,000 in Grants to Combat Childhood Obesity 3Health News:ING Awards $100,000 in Grants to Combat Childhood Obesity 4Health News:ING Awards $100,000 in Grants to Combat Childhood Obesity 5Health News:New Therapy Spares Organ in Early Esophageal Cancer 2Health News:SAGE to publish leading international headache journal Cephalalgia 2Health News:Researchers link inflammatory diseases to increased cardiovascular risk 2
(Date:7/25/2014)... NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION, ... OR FROM ANY JURISDICTION WHERE TO DO SO WOULD CONSTITUTE ... JURISDICTION AbbVie (NYSE: ABBV ) today announced financial ... "This was another very strong quarter for AbbVie, ... original guidance and announced plans to merge with Shire, a ...
(Date:7/25/2014)... N.Y. , July 25, 2014 /PRNewswire-iReach/ -- Dr. ... clinic, GPM Pediatrics, reacts to a recent study, which ... Photo - http://photos.prnewswire.com/prnh/20140723/129709 ... exposed to severe stress are more likely than others to ... months before pregnancy." There were two specific types ...
(Date:7/24/2014)... July 24, 2014  Parnell Pharmaceuticals Holdings Ltd ... will be added to Parnell,s already extensive pipeline ... Ltd, a biotechnology company. The compounds now known ... promise in bone regeneration and dermal regeneration, respectively. ... compounds for the veterinary market with the potential ...
Breaking Medicine Technology:AbbVie Reports Second-Quarter 2014 Financial Results 2AbbVie Reports Second-Quarter 2014 Financial Results 3AbbVie Reports Second-Quarter 2014 Financial Results 4AbbVie Reports Second-Quarter 2014 Financial Results 5AbbVie Reports Second-Quarter 2014 Financial Results 6AbbVie Reports Second-Quarter 2014 Financial Results 7AbbVie Reports Second-Quarter 2014 Financial Results 8AbbVie Reports Second-Quarter 2014 Financial Results 9AbbVie Reports Second-Quarter 2014 Financial Results 10AbbVie Reports Second-Quarter 2014 Financial Results 11AbbVie Reports Second-Quarter 2014 Financial Results 12AbbVie Reports Second-Quarter 2014 Financial Results 13AbbVie Reports Second-Quarter 2014 Financial Results 14AbbVie Reports Second-Quarter 2014 Financial Results 15AbbVie Reports Second-Quarter 2014 Financial Results 16AbbVie Reports Second-Quarter 2014 Financial Results 17AbbVie Reports Second-Quarter 2014 Financial Results 18AbbVie Reports Second-Quarter 2014 Financial Results 19AbbVie Reports Second-Quarter 2014 Financial Results 20AbbVie Reports Second-Quarter 2014 Financial Results 21AbbVie Reports Second-Quarter 2014 Financial Results 22AbbVie Reports Second-Quarter 2014 Financial Results 23AbbVie Reports Second-Quarter 2014 Financial Results 24AbbVie Reports Second-Quarter 2014 Financial Results 25AbbVie Reports Second-Quarter 2014 Financial Results 26AbbVie Reports Second-Quarter 2014 Financial Results 27AbbVie Reports Second-Quarter 2014 Financial Results 28AbbVie Reports Second-Quarter 2014 Financial Results 29AbbVie Reports Second-Quarter 2014 Financial Results 30AbbVie Reports Second-Quarter 2014 Financial Results 31AbbVie Reports Second-Quarter 2014 Financial Results 32AbbVie Reports Second-Quarter 2014 Financial Results 33AbbVie Reports Second-Quarter 2014 Financial Results 34AbbVie Reports Second-Quarter 2014 Financial Results 35AbbVie Reports Second-Quarter 2014 Financial Results 36
... adjusted for perfect focus where it's needed ... This, along with Keeler's wide angle light ... the patient's pupil size, you will see ... Lithium-ion technology provides a longer life battery ...
... adjusted for perfect focus where it's needed ... This, along with Keeler's wide angle light ... the patient's pupil size, you will see ... Lithium-ion technology provides a longer life battery ...
... Keeler ophthalmoscopes are individually adjusted for ... the eye, not on paper. This, along ... infinity focus, ensures that whatever the patient's ... and largest field of view. Lithium-ion technology ...
The Beta 200S combines Heine's patented aspherical optics (U.S. Pat. 4.963.014) and a single-step Rekoss disk with a range of 36 to +38 dpt. to provide perfectly-focused images even in cases of high ...
Medicine Products: