Navigation Links
PTSD: The serotonin system influences vulnerability and treatment
Date:6/17/2010

Philadelphia, PA, 17 June, 2010 - There is a great deal of interest in factors that contribute to the vulnerability to developing post-traumatic stress disorder, or PTSD. One factor that appears to contribute to the heritable vulnerability to PTSD is a variation in the gene that codes for the serotonin transporter, also known as the serotonin uptake site. Having a shorter version of the serotonin transporter gene appears to increase one's risk for depression and PTSD after exposure to extremely stressful situations. This same gene variant increases the activation of an emotion control center in the brain, the amygdala. More recently, scientists began focusing on factors contributing to resilience to the impact of stress exposure. Could the same gene that contributes to the vulnerability to PTSD be implicated in the recovery from PTSD?

In their new study appearing in Biological Psychiatry, Dr. Richard Bryant and colleagues assessed whether serotonin transporter genotype predicted a change in patients' PTSD severity following treatment. Specifically, patients with PTSD were classified according to their genotype, and they received eight weeks of cognitive behavior therapy. Approximately one-third of patients do not respond to this treatment, and this study has now demonstrated that there may be a genetic basis for not responding to this therapy.

Dr. Bryant explained: "Patients with PTSD who carried the short allele of the serotonin transporter gene promoter responded more poorly to treatment than other PTSD patients. This study highlights that the serotonin system is implicated in responding to cognitive behavior therapy."

The recent focus on personalized medicine has emphasized the impact of variation in genes that influence the responses to medications. This study supports the reasoning that genetic variation would also influence the response to psychotherapeutic or rehabilitative treatments.

Dr. John
'/>"/>

Contact: Maureen Hunter
m.hunter@elsevier.com
215-239-3674
Elsevier
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Healthy Serotonin Levels Shown to Positively Affect many Important Functions of the Mind and Body.
2. Serotonin May Be Key to Sudden Infant Deaths
3. Unlocking the Immune System's Response to Infection and Injury
4. Action of modern drug demonstrates how 2 ancient human systems interact
5. Comparing Tuition and Fees Just Got Easier With College Equalizer, the New Revolutionary College Search System Set to Launch Soon
6. VA Maryland Health Care System's Summer Health Tips
7. New ICD-10 Training Tools Released with 3M Coding and Reimbursement System
8. Harmony Information Systems Announces Availability of Harmony for Aging Provider Direct
9. How bacteria boost the immune system
10. New promising therapy against systemic sclerosis
11. Global LMS Provider CERTPOINT Systems Welcomed as Sponsor of Learning and Skills Group
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... of Texas MD Anderson Cancer Center today announced a ... breast screening at a network of community breast care ... late November, MD Anderson will become the exclusive provider ... Hermann,s 10 breast care centers, located in Memorial City, ... time, the network will expand to Memorial Hermann,s locations ...
(Date:8/21/2014)... 21, 2014 (HealthDay News) -- Black mothers are less ... here,s one possible reason why: Hospitals in neighborhoods with ... those in areas with more white residents, a U.S. ... are much less common in medical centers where the ... U.S. Centers for Disease Control and Prevention reported Thursday. ...
(Date:8/21/2014)... By Dennis Thompson ... (HealthDay News) -- A combination of therapy and antidepressants ... depression, a new study reports. Four out of ... two years experienced full recovery when treated with cognitive ... other hand, the combination didn,t work much better than ...
(Date:8/21/2014)... Seattle, WA chiropractors Dr. Lincoln ... Chiropractic and Massage Center have recently welcomed two ... Rina Lang, LMP and Mike Larios, LMP have specialized ... techniques, and have developed their expertise working in a ... important in a clinical environment where massage is used ...
(Date:8/21/2014)... (PRWEB) August 21, 2014 The results ... today in The Journal of the American Medical Association ... invasive cancers and reduces unnecessary recalls. Memorial Healthcare System ... the study. , “This study confirms what we already ... harmful cancers we want to find and, at the ...
Breaking Medicine News(10 mins):Health News:MD Anderson and Memorial Hermann to operate breast screening network across Houston area 2Health News:Racial Disparities in Breast-Feeding May Start With Hospitals, Study Suggests 2Health News:Talk Therapy Plus Meds May Be Best for Severe Depression 2Health News:Talk Therapy Plus Meds May Be Best for Severe Depression 3Health News:Seattle’s Eastlake Chiropractic and Massage Center Is Pleased to Introduce Rina Lang and Mike Larios as New Members of Its Massage Therapy Team 2Health News:Seattle’s Eastlake Chiropractic and Massage Center Is Pleased to Introduce Rina Lang and Mike Larios as New Members of Its Massage Therapy Team 3Health News:Dr. Mary Hayes: Study Shows 3D Mammography Finds More Invasive Cancers While Reducing Unnecessary Recalls 2
... The More You Know, the More You Care About ... Action for World,s Leaders,to ,Put a Face on the ... 25 years,after HIV was discovered, one-third of the people ... about the global HIV and AIDS epidemic,and one-fourth believe ...
... Peninsula Medical School in the South West of England ... providing out of hours services in primary care are ... discussions and carried out telephone interviews with 27 patients ... general practice cover in the evenings and weekends in ...
... female hormone , THURSDAY, Nov. 29 (HealthDay News) -- ... given with estrogen in hormone replacement therapy -- offers ... , They conducted tests on female mice genetically engineered ... conclusion. , Treatment with estrogen blocked the Alzheimer,s-like symptoms ...
... 29 S3 Matching Technologies,patented TeraMatch(R) has ... (TMHP) innovative technology to automate the verification ... that Medicaid does not,allow payments to non-qualified ... TMHP relied on manual data verification searches ...
... to Create New, Database File Storage System to ... Nov. 29 ONStor Inc., the leading,provider of ... that Consortium Health Plans, Inc., a national consortium ... has chosen the ONStor,Bobcat Series NAS Gateway as ...
... STAAR Surgical,Company (Nasdaq: STAA ), a ... products, today announced that it will,present at the ... on,Tuesday, December 4, 2007 at the Millennium Broadway ... Surgical,s Chief Executive Officer, will,discuss the Company,s business ...
Cached Medicine News:Health News:AIDS Ignorance: One-Third of Adults Admit Little or No Knowledge of Pandemic 2Health News:AIDS Ignorance: One-Third of Adults Admit Little or No Knowledge of Pandemic 3Health News:AIDS Ignorance: One-Third of Adults Admit Little or No Knowledge of Pandemic 4Health News:Out-of-hours doctors reluctant to do home visits, say patients 2Health News:Progesterone Won't Shield Women Against Alzheimer's 2Health News:S3 Matching Technologies Aids in Reducing Risk to Texas Medicaid System 2Health News:Consortium Health Plans Cuts Down on Power Usage and Cooling in Its Data Center Using ONStor's Green Clustered NAS Solution 2Health News:Consortium Health Plans Cuts Down on Power Usage and Cooling in Its Data Center Using ONStor's Green Clustered NAS Solution 3Health News:STAAR Surgical to Present at the BMO Capital Markets Focus on Healthcare Conference 2
(Date:8/21/2014)... ARMONK , N.Y. and HAMBURG, Germany ... today announced it is collaborating with Deutsches Elektronen-Synchrotron ( ... Germany , to speed up management and ... Big Data and Analytics architecture based on ... gigabyte per second of data at peak performance and ...
(Date:8/21/2014)... 2014  ACI Clinical ( www.aciclinical.com ) announces ... Committees. Using this solution, trial sponsors ... standard costs and receive the same expertise that ... services. Leveraging a decade of DMC ... development, statistical programming and meeting facilitation), ACI analyzed ...
(Date:8/21/2014)... 21, 2014 CVS Caremark Corporation (NYSE: ... Yields and consideration payable in connection with its previously announced ... 2014 for (1) any and all of its 6.250% Senior ... up to a maximum amount of its 6.125% Senior Notes ... Notes due 2017 (collectively, the "Maximum Tender Offer Notes" and ...
Breaking Medicine Technology:DESY and IBM Develop Big Data Architecture for Science 2DESY and IBM Develop Big Data Architecture for Science 3ACI Clinical: Innovation and Savings in Data Safety Monitoring Committees 2CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 2CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 3CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 4CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 5CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 6
This free-standing work station safely ventilates fumes upwards, away from the work surface. Optional Exhaust Purification System features bonded charcoal filters that remove organic chemical vapors ...
... is the same as model ... flat internal baffle across the ... baffle slopes forward, leaving space ... sweep the deck and space ...
... The Benchtop Fume Hood is an ... installations in which a number of fume ... schools, junior colleges and universities. Features include ... polyethylene with rounded inside corners for easy ...
This is the second generation of the famous A/O sliding microtome, manufactured in the United States under the Leica trademark....
Medicine Products: