Navigation Links
PTSD: The serotonin system influences vulnerability and treatment
Date:6/17/2010

Philadelphia, PA, 17 June, 2010 - There is a great deal of interest in factors that contribute to the vulnerability to developing post-traumatic stress disorder, or PTSD. One factor that appears to contribute to the heritable vulnerability to PTSD is a variation in the gene that codes for the serotonin transporter, also known as the serotonin uptake site. Having a shorter version of the serotonin transporter gene appears to increase one's risk for depression and PTSD after exposure to extremely stressful situations. This same gene variant increases the activation of an emotion control center in the brain, the amygdala. More recently, scientists began focusing on factors contributing to resilience to the impact of stress exposure. Could the same gene that contributes to the vulnerability to PTSD be implicated in the recovery from PTSD?

In their new study appearing in Biological Psychiatry, Dr. Richard Bryant and colleagues assessed whether serotonin transporter genotype predicted a change in patients' PTSD severity following treatment. Specifically, patients with PTSD were classified according to their genotype, and they received eight weeks of cognitive behavior therapy. Approximately one-third of patients do not respond to this treatment, and this study has now demonstrated that there may be a genetic basis for not responding to this therapy.

Dr. Bryant explained: "Patients with PTSD who carried the short allele of the serotonin transporter gene promoter responded more poorly to treatment than other PTSD patients. This study highlights that the serotonin system is implicated in responding to cognitive behavior therapy."

The recent focus on personalized medicine has emphasized the impact of variation in genes that influence the responses to medications. This study supports the reasoning that genetic variation would also influence the response to psychotherapeutic or rehabilitative treatments.

Dr. John
'/>"/>

Contact: Maureen Hunter
m.hunter@elsevier.com
215-239-3674
Elsevier
Source:Eurekalert

0

GOOD

Page: 1 2

Related medicine news :

1. Healthy Serotonin Levels Shown to Positively Affect many Important Functions of the Mind and Body.
2. Serotonin May Be Key to Sudden Infant Deaths
3. Unlocking the Immune System's Response to Infection and Injury
4. Action of modern drug demonstrates how 2 ancient human systems interact
5. Comparing Tuition and Fees Just Got Easier With College Equalizer, the New Revolutionary College Search System Set to Launch Soon
6. VA Maryland Health Care System's Summer Health Tips
7. New ICD-10 Training Tools Released with 3M Coding and Reimbursement System
8. Harmony Information Systems Announces Availability of Harmony for Aging Provider Direct
9. How bacteria boost the immune system
10. New promising therapy against systemic sclerosis
11. Global LMS Provider CERTPOINT Systems Welcomed as Sponsor of Learning and Skills Group
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2012)... (HealthDay News) -- New research suggests that young asthma ... such as ipratropium [Atrovent] -- could be more likely ... However, the increased risk was not seen ... raises concern because of the recent interest in use ... the University of Illinois at Chicago, said in a ...
(Date:5/23/2012)... Prior treatment with inhaled corticosteroids in patients ... (CAP) is associated with a lower incidence and ... study from researchers in Spain. , A parapneumonic ... fluid that accumulates between the two pleural layers, ... arises as a result of a pneumonia, lung ...
(Date:5/22/2012)... OAK BROOK, Ill. Magnetic resonance imaging (MRI) ... to pre-surgical chemotherapy significantly earlier than possible through ... online in the journal Radiology . ... prior to surgery. Research has shown that women ... are more likely to achieve breast conservation than ...
(Date:5/22/2012)... By Carina Storrs HealthDay Reporter , , TUESDAY, ... treating obstructive sleep apnea, a common cause of snoring ... serious health hazard associated with the condition -- the ... Spain examined the number of new cases of high ... used continuous positive airway pressure therapy, or CPAP, for ...
(Date:5/22/2012)... Researchers at Barrow Neurological Institute at St. Joseph,s ... why the public perceives some magic tricks in ... military tactics, marketing and sports. , Susana Martinez-Conde, ... Stephen Macknik, PhD, of Barrow,s Laboratory of Behavioral ... magic and illusions. Their most recent original research ...
Breaking Medicine News(10 mins):Health News:Asthma Meds May Be Linked to Irregular Heartbeat 2Health News:Long-term ICS use reduces pleural effusion in patients with CAP 2Health News:Breast MRI helps predict chemotherapy's effectiveness 2Health News:Sleep Apnea 'Mask' Might Also Help the Heart 2Health News:Sleep Apnea 'Mask' Might Also Help the Heart 3Health News:Sleep Apnea 'Mask' Might Also Help the Heart 4Health News:Barrow researchers use magic for discoveries 2
... levels of certain cytokines spiked during disease stage , , ... Africa recently had the rare opportunity to follow the ... recovery in a 29-year-old lab worker who had accidentally ... the researchers followed the trajectory of cytokines, a type ...
... ATLANTA Georgia State University and the Georgia Institute ... provide researchers around Atlanta with a dedicated magnetic resonance ... the brain and mind. , The Center for Advanced ... Georgia Tech, opened this month for researchers exploring topics ...
... disease recurrence, death nearly twice that of normal-weight patients ... cancer patients are more likely than non-obese patients to ... say U.S. researchers. , "We identified a subset ... at 12-fold increased risk of lymph node metastasis compared ...
... until Executive Search for Replacement is CompletedPlanned Investor ... at 4:15 PM ET LIVINGSTON, N.J., March ... MLSS), the recognized leader in advanced injection technologies, ... Board, will temporarily assume the post of Interim ...
... The American Academy of Nurse Practitioners (AANP) announces the ... AANP Chief Executive Officer, effective March 20, 2009. ... will retire after 13 years as CEO of AANP. ... in her role as Executive Director of the AANP ...
... Event held in partnership with Children,s Hospital of Michigan ... for vehicle travelProper use of booster seats and car ... road , DETROIT, March 18 Parents and caregivers ... children for vehicle travel during the Second Annual ...
Other Medicine News:Health News:Course of West Nile Infection Charted 2Health News:Course of West Nile Infection Charted 3Health News:Georgia State/Georgia Tech Center for Advanced Brain Imaging to expand brain, mind research 2Health News:Obesity Tied to Poor Pancreatic Cancer Surgery Outcomes 2Health News:Milestone Scientific Announces Resignation of CEO 2Health News:Milestone Scientific Announces Resignation of CEO 3Health News:American Academy of Nurse Practitioners Announces New Chief Executive Officer 2Health News:Wayne County Community College District Presents Second Annual Child Car Seat Check Program 2
(Date:5/23/2012)... 2012  Insmed Incorporated (Nasdaq CM: INSM), a biopharmaceutical ... for its U.S. phase 2 clinical trial, T ... G reater E fficacy T rial ... in patients with non-tuberculous mycobacterial (NTM) lung disease. ... to support current NTM treatment recommendations, and no new ...
(Date:5/23/2012)... Calif., May 23 2012  Isis Pharmaceuticals, Inc. ... webcast:What:Data from KYNAMRO™ presented at EAS 2012When:Friday, June ... PTWhere:www.isispharm.comHow:Live on the Internet.  Simply log onto our ... to participate during the live event, a replay ... limited time at www.isispharm.com . ...
(Date:5/23/2012)... 2012 Reportlinker.com announces that a new ... The Medical Device Market: ... Summary Espicom,s in-depth medical ... to understand the key drivers in medical markets ... data. Each report opens with an outlook section ...
Breaking Medicine Technology:Insmed Incorporated Begins Screening Patients For TARGET-NTM U.S. Clinical Trial Of ARIKACE® In Patients With Non-tuberculous Mycobacterial Lung Disease 2Insmed Incorporated Begins Screening Patients For TARGET-NTM U.S. Clinical Trial Of ARIKACE® In Patients With Non-tuberculous Mycobacterial Lung Disease 3Insmed Incorporated Begins Screening Patients For TARGET-NTM U.S. Clinical Trial Of ARIKACE® In Patients With Non-tuberculous Mycobacterial Lung Disease 4Insmed Incorporated Begins Screening Patients For TARGET-NTM U.S. Clinical Trial Of ARIKACE® In Patients With Non-tuberculous Mycobacterial Lung Disease 5The Medical Device Market: USA 2The Medical Device Market: USA 3The Medical Device Market: USA 4The Medical Device Market: USA 5The Medical Device Market: USA 6The Medical Device Market: USA 7The Medical Device Market: USA 8Micromet to Present at the UBS Global Life Sciences Conference on September 22 2009 14100 1Micromet to Present at the UBS Global Life Sciences Conference on September 22 2009 14100 2Micromet to Present at the UBS Global Life Sciences Conference on September 22 2009 14100 3Hard to Treat Diseases Inc 28HTDS 29 Attorney Brad Essman Uncovers Reports of Retail Brokers Making False Statements 57385 1Hard to Treat Diseases Inc 28HTDS 29 Attorney Brad Essman Uncovers Reports of Retail Brokers Making False Statements 57385 2Hard to Treat Diseases Inc 28HTDS 29 Attorney Brad Essman Uncovers Reports of Retail Brokers Making False Statements 57385 3Hard to Treat Diseases Inc 28HTDS 29 Attorney Brad Essman Uncovers Reports of Retail Brokers Making False Statements 57385 4Internet Can Help Curb Drinking Among College Students 57382 1Internet Can Help Curb Drinking Among College Students 57382 2
... Efficacy Results Support Follow-on NEST-3 TrialCARLSBAD, Calif., Feb. ... PhotoThera, Inc., transcranial laser therapy (TLT) for acute ... demonstrated improved outcomes for patients, but did not ... analysis in patients who had moderate to moderately ...
... Bulletin Board: GOVX), an Atlanta-based, publicly traded,biopharmaceutical company ... Immunodeficiency Virus) and other infectious agents, announced,the first ... Trial for its,candidate HIV/AIDS vaccine. The trial, ... Vaccine Trials Network (HVTN). The HVTN, funded ...
Other Medicine Technology:Results of NeuroThera Effectiveness and Safety Trial - 2 (NEST-2) Presented at International Stroke Conference 2009 2GeoVax Starts Injections for Phase 2a Human HIV/AIDS Vaccine Trial in USA 2GeoVax Starts Injections for Phase 2a Human HIV/AIDS Vaccine Trial in USA 3GeoVax Starts Injections for Phase 2a Human HIV/AIDS Vaccine Trial in USA 4GeoVax Starts Injections for Phase 2a Human HIV/AIDS Vaccine Trial in USA 5
... onlays are pre-cut and pre-shaped to facilitate ... more frequently done. These pre-shaped onlays are ... Ultra and are designed for use in ... both small and large sizes, they provide ...
... and soft tissue reconstructions, and in ... is sometimes necessary to encourage host ... minimizing tissue attachment along another surface.,GORE ... ePTFE sheet material that offers a ...
... is pleased to announce the latest advancement ... E/X mesh.,When Bard Composix mesh was introduced ... hernia repair prosthesis that combined two clinically ... in one product. Bard Composix E/X mesh, ...
... introduction in 1958, Bard mesh has become ... are compared. Bard mesh was used by ... the "tension-free" hernia repair many years ago. ... and ideal" substance for permanent reinforcement of ...
Medicine Products: