Navigation Links
PSA testing, combined with other relevant patient data can reduce unnecessary prostate biopsies
Date:12/8/2011

by adjusting PSA results for other considerations such as family history, obesity, and prostate size.

Results from the multi-center study that suggest that PSAD levels of less than 0.1 in contrast to the unadjusted level of between 2.5 and 4 can be a better benchmark of a potential cancer. The density, determined by a digital rectal exam, enables physicians to take into account other factors like benign prostatic hyperplasia, an enlargement of the gland that affects all men as they age.

Combining the PSAD with the digital exam, a look at the patient's family history and a body mass index of 25 of less the calculation used to define obesity would avoid biopsy in approximately one-quarter of biopsy-eligible men, the researchers found.

"Urological practice, patient outcome and cost-effectiveness of health care would each benefit from new targeted strategies, such as nomograms (a predictive tool) that improve prediction of aggressive cancers, to enable selective identification of candidate for prostate biopsy that would improve the yield of clinically significant, histologically aggressive cancers warranting subsequent definitive treatment," researchers wrote.

In a separate multicenter study published in Urologic Oncology, researchers said a test looking for two specific genetic biomarkers TMPRSS2:ERG and PCA3 taken after a digital rectal exam, could help limit biopsies to men who possess both genes and whose PSA readings range between 2 and 10, potentially sparing one-third of men from biopsies.

"Urine testing for prostate cancer is in its infancy," says Sanda, noting next steps are underway as a result of study funded by a $3.1 million grant from the National Institutes of Health , that is evaluating new urine and blood test for prostate cancer in more 2,400 men over the next five years with a goal of improving upon the problems of over-diagnosis and over-treatment.

A focal point of the proposed work involves
'/>"/>

Contact: Jerry Berger
jberger@bidmc.harvard.edu
617-667-7308
Beth Israel Deaconess Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Adults in Puerto Rico aware of genetic testing, but use remains low
2. Combined arterial imaging technology reveals both structural and metabolic details
3. Novel combined therapy extends life, diminishes pain in brain cancer patients
4. Ultrasound combined with pre-operative MRI is cost effective in evaluating rotator cuff tears
5. Combined imaging technologies may better identify cancerous breast lesions
6. Combined BRAF-targeted and immunotherapy shows promise for melanoma treatment
7. Vandetanib shows clinical benefit when combined with docetaxel for lung cancer
8. New Laser Technology Combined with Manual Physical Therapy Offer Pain Relief to Chronic Pain Sufferers
9. Singapore Performs Asia's First Combined Heart and Liver Transplant
10. Promega Maxwell 16 IVD System CE Marked to the European Union IVD Directive Delivers Combined Solution for Infectious Disease
11. ACCORD: Intensive BP, combined lipid therapies do not help adults with diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/26/2014)... Plugin and template developers from Pixel ... for Final Cut Pro X. , “TransPack Volume 5 gives ... pull off an industry professional look” Said Christina Austin, CEO ... TransPack Volume 5, a new level of professionalism will become ... over 50 Final Cut Pro X transitions featuring organic animations. ...
(Date:12/26/2014)... Parker & Sons, Inc. a ... heating, cooling and plumbing contractor services throughout Arizona ... in 2014 with regard to air-conditioning systems. Residential ... known for its incredibly hot summers. Working with ... and details of a wide variety of systems ...
(Date:12/25/2014)... The report “TS-1 (Colorectal Cancer) – Forecast and ... landscape, unmet needs, current pipeline and commercial opportunities in ... which is typically used for treating colorectal cancer. It ... gastric cancer and pancreatic cancer. TS-1 is composed of ... approved in 1999 in Japan for the treatment of ...
(Date:12/25/2014)... The short film “Color of Honor” by young director/producer ... true 9/11 hero, Welles Remy Crowther. It has been chosen ... of Nuremberg International Short Film Festival and the 8th International ... and director Luciana Lagana plays the mother of the ... Gregory Graham - Graham plays a heroic policeman ...
(Date:12/25/2014)... Recently, LunaDress.co.uk has updated its blog to provide professional shopping tips ... the models at LunaDress.co.uk come with big discounts, up to 80 ... can turn out to be a most exciting memory and can ... bring surprise to a wedding. On the updated fashion blog, ladies ... for a big day . , Going out with friends to ...
Breaking Medicine News(10 mins):Health News:Today a new plugin was announced from Pixel Film Studios, TransPack Volume 5 for Final Cut Pro X 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 3Health News:TS-1 Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 2Health News:TS-1 Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 3Health News:The True 9/11 Hero Story “Color of Honor” Premieres in Germany and Bangladesh: Luciana Lagana Plays the Mother of the Lead and Co-Produces with Blaise Dolcemaschio. 2Health News:The True 9/11 Hero Story “Color of Honor” Premieres in Germany and Bangladesh: Luciana Lagana Plays the Mother of the Lead and Co-Produces with Blaise Dolcemaschio. 3Health News:LunaDress Provides Professional Tips On Shopping Wedding And Prom Dresses 2
... (PPS®), renowned for its award-winning healthcare ... on-demand, interactive case study, Beyond Basic ... Mid-Face Volumizing, now available on AestheticEnhance.org. ... treatment options for the use of ...
... of burning in the sun, but many people still look and feel better ... selection of branded self tan products. These have been categorised on their ... to suit their needs. , ... (PRWEB) July 8, 2008 -- Everyone is aware of ...
... African American ... participants, PORTLAND, Ore., July ... to a study from Kaiser Permanente,s Center,for Health Research. The findings, from ... will be published in,the August issue of the American Journal of Preventive ...
... Medicine (BUSM) and Boston Medical Center (BMC) found that ... clinicians of any type did not experience serious harm. ... or obstetrics/gynecology setting received the most benefit. The findings, ... Journal , also conclude that disclosures made in an ...
... Cancer Research,Center challenged a team of elite climbers to ... the efforts of researchers to eliminate,cancer as a cause ... mountaineers on the Big Expedition for Cancer Research has,recently ... reaching the 7,800-foot level of an unclimbed, unnamed peak, ...
... review article in leading hypertension journal suggests that increasing, ... ... are good sources of potassium and low in sodium ... high blood pressure and stroke, ENGLEWOOD CLIFFS, N.J., July 7 ...
Cached Medicine News:Health News:AestheticEnhance.org Launches CME-Certified Case Study on Mid-Face Volumizing 2Health News:AestheticEnhance.org Launches CME-Certified Case Study on Mid-Face Volumizing 3Health News:Beauty Counter Direct Leads Customers Through the Maze of Self Tanning Products 2Health News:Beauty Counter Direct Leads Customers Through the Maze of Self Tanning Products 3Health News:Kaiser Permanente Study Finds Keeping a Food Diary Doubles Diet Weight Loss 2Health News:Kaiser Permanente Study Finds Keeping a Food Diary Doubles Diet Weight Loss 3Health News:Kaiser Permanente Study Finds Keeping a Food Diary Doubles Diet Weight Loss 4Health News:Disclosing violence to primary care or obstetrics/gynecology physicians most beneficial 2Health News:Inaugural Big Expedition for Cancer Research Encounters Mountain As Challenging As Finding a Cure for Cancer 2Health News:Inaugural Big Expedition for Cancer Research Encounters Mountain As Challenging As Finding a Cure for Cancer 3Health News:Inaugural Big Expedition for Cancer Research Encounters Mountain As Challenging As Finding a Cure for Cancer 4Health News:Unilever Unveils Promise(R) SuperShots(R) for Blood Pressure, the First Functional Shot to Increase Daily Potassium Intake to Help Reduce the Risk of High Blood Pressure 2Health News:Unilever Unveils Promise(R) SuperShots(R) for Blood Pressure, the First Functional Shot to Increase Daily Potassium Intake to Help Reduce the Risk of High Blood Pressure 3Health News:Unilever Unveils Promise(R) SuperShots(R) for Blood Pressure, the First Functional Shot to Increase Daily Potassium Intake to Help Reduce the Risk of High Blood Pressure 4Health News:Unilever Unveils Promise(R) SuperShots(R) for Blood Pressure, the First Functional Shot to Increase Daily Potassium Intake to Help Reduce the Risk of High Blood Pressure 5
(Date:12/24/2014)... N.C. , Dec. 23, 2014  Endo Pharmaceuticals ... ENDP ) (TSX: ENL), and BioDelivery Sciences International, ... they have submitted a New Drug Application (NDA) for ... Drug Administration (FDA).  Buprenorphine HCl Buccal Film is under ... require daily, around-the-clock, long-term opioid treatment and for which ...
(Date:12/22/2014)... , Dec. 22, 2014 Research and Markets ... of the "US Self-monitoring Blood Glucose Market" ... http://photos.prnewswire.com/prnh/20130307/600769 This market insight focuses on ... the United States . Reimbursement analysis ... Thorough product analyses for more than 73 SMBG meters ...
(Date:12/22/2014)... , Dec. 22, 2014 Swedish Orphan ... today announced that the Committee for Medicinal Products for ... has adopted a positive opinion for the use of ... men with Peyronie,s disease with a palpable plaque and ... start of therapy. The use of Xiapex ...
Breaking Medicine Technology:Endo Pharmaceuticals and BioDelivery Sciences Announce NDA Submission for Buprenorphine HCl Buccal Film for the Management of Moderate to Severe Chronic Pain 2Endo Pharmaceuticals and BioDelivery Sciences Announce NDA Submission for Buprenorphine HCl Buccal Film for the Management of Moderate to Severe Chronic Pain 3Endo Pharmaceuticals and BioDelivery Sciences Announce NDA Submission for Buprenorphine HCl Buccal Film for the Management of Moderate to Severe Chronic Pain 4Endo Pharmaceuticals and BioDelivery Sciences Announce NDA Submission for Buprenorphine HCl Buccal Film for the Management of Moderate to Severe Chronic Pain 5US Self-monitoring Blood Glucose Market 2Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 2Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 3Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 4Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 5Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 6
... (Nasdaq: ENMD ), a clinical-stage pharmaceutical company ... that Selected Value Therapeutics I, LLC (SVT) has exercised ... and commercialize EntreMed,s Phase 2 oncology drug candidate, ENMD-2076, ... development and commercialization rights to ENMD-2076 in the rest ...
... 2011 The ALS Therapy Development Institute (ALS TDI) ... (D-MA) with its first ever "Lou Gehrig Award" during ... event this November 3rd.  The award recognizes the Congressman ... additional funding for research leading to an effective treatment ...
Cached Medicine Technology:Selected Value Therapeutics Exercises Right to Develop and Commercialize ENMD-2076 in China 2Selected Value Therapeutics Exercises Right to Develop and Commercialize ENMD-2076 in China 3Selected Value Therapeutics Exercises Right to Develop and Commercialize ENMD-2076 in China 4U.S. Congressman Michael Capuano to Receive "Lou Gehrig Award" from ALS TDI During Gala Event this November 2
Silicone ICD lead...
... Medtronic Subcutaneous Lead System Model ... with the use of the ... Improved SQ design and implant ... fast and easy procedure, and ...
The Livewire steerable electrophysiology catheter is uniquely designed with an ergonomic handle and patented steering mechanism to provide smooth, precise catheter tip movement, even during lengthy e...
... The Medtronic Sprint™ ... and the CapSureFix® Novus ... deliver superior electrical performance ... excellent sensing capabilities, low ...
Medicine Products: