Navigation Links
PSA testing, combined with other relevant patient data can reduce unnecessary prostate biopsies
Date:12/8/2011

by adjusting PSA results for other considerations such as family history, obesity, and prostate size.

Results from the multi-center study that suggest that PSAD levels of less than 0.1 in contrast to the unadjusted level of between 2.5 and 4 can be a better benchmark of a potential cancer. The density, determined by a digital rectal exam, enables physicians to take into account other factors like benign prostatic hyperplasia, an enlargement of the gland that affects all men as they age.

Combining the PSAD with the digital exam, a look at the patient's family history and a body mass index of 25 of less the calculation used to define obesity would avoid biopsy in approximately one-quarter of biopsy-eligible men, the researchers found.

"Urological practice, patient outcome and cost-effectiveness of health care would each benefit from new targeted strategies, such as nomograms (a predictive tool) that improve prediction of aggressive cancers, to enable selective identification of candidate for prostate biopsy that would improve the yield of clinically significant, histologically aggressive cancers warranting subsequent definitive treatment," researchers wrote.

In a separate multicenter study published in Urologic Oncology, researchers said a test looking for two specific genetic biomarkers TMPRSS2:ERG and PCA3 taken after a digital rectal exam, could help limit biopsies to men who possess both genes and whose PSA readings range between 2 and 10, potentially sparing one-third of men from biopsies.

"Urine testing for prostate cancer is in its infancy," says Sanda, noting next steps are underway as a result of study funded by a $3.1 million grant from the National Institutes of Health , that is evaluating new urine and blood test for prostate cancer in more 2,400 men over the next five years with a goal of improving upon the problems of over-diagnosis and over-treatment.

A focal point of the proposed work involves
'/>"/>

Contact: Jerry Berger
jberger@bidmc.harvard.edu
617-667-7308
Beth Israel Deaconess Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Adults in Puerto Rico aware of genetic testing, but use remains low
2. Combined arterial imaging technology reveals both structural and metabolic details
3. Novel combined therapy extends life, diminishes pain in brain cancer patients
4. Ultrasound combined with pre-operative MRI is cost effective in evaluating rotator cuff tears
5. Combined imaging technologies may better identify cancerous breast lesions
6. Combined BRAF-targeted and immunotherapy shows promise for melanoma treatment
7. Vandetanib shows clinical benefit when combined with docetaxel for lung cancer
8. New Laser Technology Combined with Manual Physical Therapy Offer Pain Relief to Chronic Pain Sufferers
9. Singapore Performs Asia's First Combined Heart and Liver Transplant
10. Promega Maxwell 16 IVD System CE Marked to the European Union IVD Directive Delivers Combined Solution for Infectious Disease
11. ACCORD: Intensive BP, combined lipid therapies do not help adults with diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... January 22, 2015 Yesterday, Senator ... (D-Concord) and Kristin Olsen (R-Modesto) were honored by ... in advancing biotechnology, biomedical science, medical device and ... each received the “2014 Life Sciences Champion” award ...
(Date:1/22/2015)... Palm City, Florida (PRWEB) January 22, 2015 ... use cold therapy machine with patented IsoTube design to treat ... has introduced the most progressive and easy to use ... help treat post-operative and sports related orthopedic and muscle injuries. ...
(Date:1/22/2015)... Payday lending practices in four southern states worsen ... to the states that permit them, according to a ... Race and Wealth. , While they generate hundreds of ... the same time substantially depress economic activity, according to ...
(Date:1/22/2015)... As interest in the value of spiritual support as ... Rev. Eric J. Hall , president and CEO of the ... the keynote speaker on January 27 at an international summit ... The conference, “Hope and Resilience: Innovative and Interdisciplinary Spiritual Care,” ...
(Date:1/22/2015)... a new blog post presenting a list of vehicles that cannot ... Some types of vehicles cannot be covered under an ordinary auto ... see if their vehicle qualifies for auto insurance coverage. , ... that cannot be covered by a plan. Clients have little options ...
Breaking Medicine News(10 mins):Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 3Health News:IsoComforter Introduces Best of Class Cold Therapy Product to the Worldwide Market 2Health News:Howard University Spotlights the Economic Impact of Payday Lending in Southern States 2Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 2Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 3Health News:Some Vehicles Cannot Be Covered By An Auto Insurance Policy! 2
... That can lead to under-reporting when applying for driver,s ... -- In patients with focal epilepsy, simply asking how ... of their seizure frequency, German research suggests. , Reminding ... not help, either, because they may be unaware of ...
... 15 Dr. Douglas Kalman of Miami Research,Associates delivered ... the,endurance athlete at the International Society of Sports Nutrition ... Kalman presented "Whey, Casein, Soy: Why Protein Sources are ... studies that examined just how, and if, these varied ...
... Mass., Nov. 15 Andy Ambrose has joined ... David Test, division sales manager. Ambrose is based ... relationships in,the south Texas region. He joins ... served as,regional vice president for the company,s retirement ...
... which don,t , THURSDAY, Nov. 15 (HealthDay News) -- Experts ... cystic fibrosis (CF). , The guidelines were based on a ... older. , "Physicians treating patients with CF are faced with ... clinicians will find these recommendations to be useful in their ...
... November 15, 2007 A recently published special ... the contributions from experts in the field of ... Fourth Annual Meeting on Brain aging and Dementia: ... Perugia in October 2006 under the auspices of ...
... to change diet, get more exercise, study found , THURSDAY, ... blood pressure are less likely than younger patients to receive ... their blood pressure, a new study finds. , A team ... data from a U.S. Centers for Disease Control and Prevention ...
Cached Medicine News:Health News:Some Epilepsy Patients Not Always Aware of Seizures 2Health News:Presentation at ISSN Highlights Soy Protein Advantages for Endurance Athletes 2Health News:Experts Release New Cystic Fibrosis Guidelines 2Health News:Journal of Alzheimer's Disease special issue explores multifaceted aspects of AD 2Health News:Journal of Alzheimer's Disease special issue explores multifaceted aspects of AD 3Health News:Older Hypertension Patients Less Likely to Get Lifestyle Advice 2
(Date:1/23/2015)... 23, 2015  Now available for sale, The Armor1 Ankle ... prevents ankle sprains by cushioning the ankle from an ... around the outside of any shoe type and allows ... still offering protection against sprains. With customers in physical ...
(Date:1/23/2015)... South Africa , Jan. 23, 2015   Leatt ... of personal protective equipment for all forms of sports, ... flagship Leatt-Brace® neck brace, announced today that the UISP ... federation, now requires all riders to wear a neck ...
(Date:1/23/2015)... and BOSTON , January 23, 2015 ... discovery and development company, is delighted to announce that the ... awarded to Miles Congreve (Vice President of Chemistry), ... Malcolm Weir (Chief Executive Officer and co-founder) for ...
Breaking Medicine Technology:The Armor1 Ankle Roll Guard is the New Breakthrough Solution for Ankle Sprain Prevention! 2Leatt Announces Neck Braces Now Required For Motocross/Minicross Racing In Italy 2Leatt Announces Neck Braces Now Required For Motocross/Minicross Racing In Italy 3Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 2Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 3Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 4
... NEW YORK, Sept. 28, 2011 Visionsense Corp announces ... was used in its 500th neurosurgical procedure with the ... (Al Lerner Chair and Vice-Chairman, Dept of Neurosurgery at ... performed a transsphenoidal resection of a pituitary adenoma in ...
... 2011 Low rates of meningococcal vaccination among adolescents ... Human Services Agency (HHSA) to join forces with the ... San Diego Meningitis Awareness Week. A national public health ... third of adolescents in California have not been vaccinated ...
Cached Medicine Technology:Local School Nurses Unite Community to Combat Low Meningitis Vaccination Rates Among Preteens and Teens in San Diego 2Local School Nurses Unite Community to Combat Low Meningitis Vaccination Rates Among Preteens and Teens in San Diego 3Local School Nurses Unite Community to Combat Low Meningitis Vaccination Rates Among Preteens and Teens in San Diego 4Local School Nurses Unite Community to Combat Low Meningitis Vaccination Rates Among Preteens and Teens in San Diego 5
FSH EIA Reproductive Markers 025-BC-1029 Follicle Stimulating Hormone...
... Dehydroepiandrosterone (5-Androstene-3-0L-17-one,Androstenolone, Dehydroisoandrosterone,Transdehydroandrosterone, DHEA) is ... blood mostly in its,sulfate form ... is based on the competition ... An,unknown amount of DHEA-S present ...
Beta-2 Microglobulin EIA Lipid / Protein Quantification 025-BC-1061...
Myoglobin EIA Lipid / Protein Quantification, Cardiovascular 024-IDC-13 Muscle Disease...
Medicine Products: