Navigation Links
PSA screening declines following publication of large trials, guidelines
Date:2/24/2011

PSA screening has declined in one large U.S. healthcare network since publication of two large screening trials and a set of guidelines, according to a study published online February 24 in the Journal of the National Cancer Institute.

In 2008, the U.S. Preventive Services Task Force issued guidelines recommending against PSA screening after age 75. The following year, investigators from two large screening trials reported contradictory results: The Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial showed no difference in prostate cancer-specific mortality between screened versus non-screened men, while the European Randomized study of Screening for Prostate Cancer trial found a 20% reduction in mortality with screening.

Steven B. Zeliadt, Ph.D., of the VA Puget Sound Health Care System, Seattle, and colleagues report that after publication of the trials, PSA testing declined in the U.S. Veterans Health Administration Pacific Northwest Network. The decline was 3 percentage points among men aged 40-54; 2.7 percentage points among those aged 55-74; and 2.2 percentage points among men aged 75 years and older.

The authors conclude that the guidelines and the trial results may have had a modest effect on PSA screening among men in the Veteran's Health Administration network.

In an editorial, Siu-Long Yao, M.D., and Grace Lu-Yao, Ph.D., of the Cancer Institute of New Jersey write that it is not surprising that the effect has been only modest, given the conflicting findings of the two large trials and other studies: "When faced with data that could be interpreted as neither strongly supportive nor decidedly unfavorable, it is natural that health-care providers and their patients might not substantially alter their practices in regard to PSA screening."


'/>"/>

Contact: Caroline McNeil
Caroline.McNeil@oup.com
301-841-1286
Journal of the National Cancer Institute
Source:Eurekalert

Page: 1

Related medicine news :

1. PSA velocity screening for prostate cancer may lead to unnecessary biopsies
2. PSA Screening for Prostate Cancer Dips in Large U.S. Health Network
3. Screening mammograms catch second breast cancers early
4. Higher volume reduces false positives in screening mammography
5. Worlds largest lung cancer screening conference to address benefits of CT scans
6. Breast cancer screening with MRI benefits women with radiation therapy history
7. Screening for cervical cancer low for immigrant women
8. Repeat MRI screening for breast cancer results in fewer false positives
9. Study finds MRSA screening saves hospitals money
10. More Screenings May Explain Higher Chlamydia Rates Among Minorities
11. Biodesign hosts international consortium on screening for lung cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2017)... ... April 24, 2017 , ... Ridgecrest Herbals makes it a point to lead ... reduce waste, and support renewable energy. They believe this is a crucial part of ... solutions for health issues, and maintain that destroying the environment in the pursuit of ...
(Date:4/24/2017)... ... ... , a national non-profit organization focusing on the prevention and early detection of breast and ... to announce Katie Thiede as their new Chief Executive Officer. In January, founder Lindsay Avner ... Board and launched a national search to find a visionary new leader to grow Bright ...
(Date:4/24/2017)... ... April 24, 2017 , ... The John P. McGovern Museum of Health and ... to track their cognitive health, and share results with their physicians. Members and guests ... the museum's website. , BrainCheck founder, Dr. David Eagleman, formerly at Baylor College of ...
(Date:4/24/2017)... , ... April 24, 2017 , ... ... within the telehealth industry, announces the company’s VideoMedicine mobile platform has launched Quick ... Available 24 hours a day, Quick Care provides patients with the option to ...
(Date:4/24/2017)... ... April 24, 2017 , ... MAP Health Management announced today ... people with addiction who are served by MAP’s patient engagement ecosystem. Lief Therapeutics ... monitors heart and breath rates to identify anxiety levels and can provide biofeedback ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... Mass. , April 20, 2017  RXi ... developing innovative therapeutics that address significant unmet medical ... data from the Company,s consumer product development program, ... at the Society for Investigative Dermatology (SID) 76 ... to advance and promote the sciences relevant to ...
(Date:4/20/2017)... -- AbbVie (NYSE: ABBV), a global biopharmaceutical company, today ... C virus (HCV) infected patients with genotype 1, ... (Child-Pugh A) achieved sustained virologic response at 12 ... pan-genotypic regimen of glecaprevir/pibrentasvir (G/P). These high SVR ... of G/P treatment without ribavirin. Patients with specific ...
(Date:4/20/2017)... Research and Markets has announced the addition of ... By Service (Manufacturing, Research), By Country, (Brazil, Mexico, Colombia, Argentina, ... to their offering. ... The Latin American pharmaceutical contract manufacturing services market is anticipated ... drug registration cost in Latin American countries and continuous economic ...
Breaking Medicine Technology: