Navigation Links
PSA screening declines following publication of large trials, guidelines
Date:2/24/2011

PSA screening has declined in one large U.S. healthcare network since publication of two large screening trials and a set of guidelines, according to a study published online February 24 in the Journal of the National Cancer Institute.

In 2008, the U.S. Preventive Services Task Force issued guidelines recommending against PSA screening after age 75. The following year, investigators from two large screening trials reported contradictory results: The Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial showed no difference in prostate cancer-specific mortality between screened versus non-screened men, while the European Randomized study of Screening for Prostate Cancer trial found a 20% reduction in mortality with screening.

Steven B. Zeliadt, Ph.D., of the VA Puget Sound Health Care System, Seattle, and colleagues report that after publication of the trials, PSA testing declined in the U.S. Veterans Health Administration Pacific Northwest Network. The decline was 3 percentage points among men aged 40-54; 2.7 percentage points among those aged 55-74; and 2.2 percentage points among men aged 75 years and older.

The authors conclude that the guidelines and the trial results may have had a modest effect on PSA screening among men in the Veteran's Health Administration network.

In an editorial, Siu-Long Yao, M.D., and Grace Lu-Yao, Ph.D., of the Cancer Institute of New Jersey write that it is not surprising that the effect has been only modest, given the conflicting findings of the two large trials and other studies: "When faced with data that could be interpreted as neither strongly supportive nor decidedly unfavorable, it is natural that health-care providers and their patients might not substantially alter their practices in regard to PSA screening."


'/>"/>

Contact: Caroline McNeil
Caroline.McNeil@oup.com
301-841-1286
Journal of the National Cancer Institute
Source:Eurekalert

Page: 1

Related medicine news :

1. PSA velocity screening for prostate cancer may lead to unnecessary biopsies
2. PSA Screening for Prostate Cancer Dips in Large U.S. Health Network
3. Screening mammograms catch second breast cancers early
4. Higher volume reduces false positives in screening mammography
5. Worlds largest lung cancer screening conference to address benefits of CT scans
6. Breast cancer screening with MRI benefits women with radiation therapy history
7. Screening for cervical cancer low for immigrant women
8. Repeat MRI screening for breast cancer results in fewer false positives
9. Study finds MRSA screening saves hospitals money
10. More Screenings May Explain Higher Chlamydia Rates Among Minorities
11. Biodesign hosts international consortium on screening for lung cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2017)... ... July 23, 2017 , ... Scientists from the University of Exeter ... of high-intensity, weight-bearing activity equivalent to a medium-paced run for pre-menopausal women, or a ... who specializes in total spine care, I understand the importance exercise can play on ...
(Date:7/23/2017)... (PRWEB) , ... July 23, 2017 , ... ... has joined Florida Pain Relief Group – Melbourne, a practice owned by Physician ... certification in interventional pain management, Dr. Stern also is certified in pediatrics, emergency ...
(Date:7/22/2017)... ... July 22, 2017 , ... The arthroscopic ... repairs the opportunity to return to sports and jobs that require heavy physical ... Sports Medicine’s Annual Meeting in Toronto, Ontario, Canada. , “We studied ...
(Date:7/21/2017)... ... July 21, 2017 , ... Roderick Crabbe ... services to families and business owners in northern Florida, is joining the First ... support to area adults with developmental challenges. , The First Coast YMCA offers ...
(Date:7/21/2017)... ... July 21, 2017 , ... Hospital M&A activity slowed in the second ... of hospital acquisitions rose to 23 in the second quarter, up 15% from the ... the 20 announced deals in the year-ago second quarter. Only four of the transactions ...
Breaking Medicine News(10 mins):
(Date:7/10/2017)... , July 10, 2017  The tenth annual ... Boston, MA at the Sheraton Boston ... and unparalleled access to global decision makers and innovative ... 800+ life science leaders during two impactful days. BioPharm ... provides delegates with additional networking opportunities with 4,500+ life ...
(Date:7/5/2017)... July 5, 2017 Oramed Pharmaceuticals ... ), a clinical-stage pharmaceutical company focused on the ... has received approval from the Israel Securities Authority to dual-list ... Oramed common stock will commence trading on the TASE on ... current market capitalization of the Company, it is expected that ...
(Date:6/30/2017)... ROCKVILLE, Md. , June 30, 2017 ... that since the start of May, at least ten ... financings include private investments, public offerings and a loan ... $3.3 million to almost $80 million.  Kalorama Information provides ... customers of its Diagnostics Knowledge Center. ...
Breaking Medicine Technology: