Navigation Links
PSA screening cuts deaths by 20 percent
Date:3/18/2009

Screening for prostate cancer can reduce deaths by 20%, according to the results of the European Randomized Study of Screening for Prostate Cancer (ERSPC) published online 1700 hours CET, today 18 March (NEJM, Online First*). ERSPC is the world's largest prostate cancer screening study and provides robust, independently audited evidence, for the first time, of the effect of screening on prostate cancer mortality.

The study commenced in the early 1990s involving eight countries Belgium, Finland, France, Italy, Netherlands, Spain, Sweden and Switzerland - with an overall follow-up of up to 12 years. Participants totalled 182,000 but then narrowed down to 162,000 men in seven countries, aged 55-69; only those who had not been screened could take part. The findings are being unveiled at the 24th Annual Congress of the European Association of Urology (EAU) in Stockholm, Sweden (17 - 21 March 2009).

By initially screening men 55 to 69 years with the PSA marker and offering regular follow up, this led to an increase in early detection. Deaths due to metastasized disease were then reduced. Exact data showed that on average for every 1,408 men screened, 48 had cancer diagnosed and received treatment, resulting in saving one life. Screening took place on average every four years with a mean follow-up over nine years. The cut-off value was a PSA level of 3.0 ng/ml or more. Men with this reading were then offered a biopsy.

Prof Fritz Schrder, international coordinator of the ERSPC study explained: "The study shows that PSA screening delivers a 20% reduction in mortality from prostate cancer. This provides decision makers on screening policies with important new data on the effectiveness of PSA testing in preventing deaths."

"However, the ERSPC is also near to completing additional studies on quality of life and cost-effectiveness and these must be assessed before making a decision about the appropriateness of a national prostate screening policy."

Worldwide, prostate cancer is the second leading cause of cancer death. Separate ERSPC findings already confirm that approximately 30% of detected cancers actually have non-aggressive features and are 'indolent' or slow growing. This overdiagnosis is an unavoidable effect from all cancer screening procedures. With prostate cancer, a new, more conservative form of monitoring, 'Active Surveillance', might be an important method to help avoid early invasive treatment.


'/>"/>

Contact: Lindy Brouwer
l.brouwer@uroweb.org
European Association of Urology
Source:Eurekalert

Related medicine news :

1. 2 Studies Conflict Over Value of Prostate Cancer Screening
2. Cancer Screening Tests Could Do More Harm Than Good: Readers Digest April Cover Story
3. Understand Colon Cancer with MyBiopsy.Org; Schedule a Screening Test at MyHealthTestReminder.Org
4. New Data Reveals That Gaps in Coverage for Those With Private Insurance Are Major Barriers to Colorectal Cancer Screening
5. March is National Colorectal Cancer Awareness Month: Do You Know What Your Screening Options Are?
6. HealthYes! Now Offering its Preventive Health Screening Services in Houston
7. ForteBio Launches New Biosensor for Kinetic Analysis and Screening of Human IgG Antibodies
8. Taking Action Together Aims to Increase Screenings and Offer Education to People with Diabetes Living in the Inland Empire
9. Economy could reduce colorectal cancer screening rate
10. Inexpensive depression screening tool works in resource poor countries
11. Mail and electronic reminders may increase colon cancer screening
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/19/2017)... ... 20, 2017 , ... Today, the Centers for Medicare & Medicaid Services (CMS) ... Payment Models (APMs) in 2017. Clinicians who participate in APMs are paid for the ... of the Administration’s effort to build a system that delivers better care and one ...
(Date:1/19/2017)... ... January 19, 2017 , ... Wells Pharmacy Network announced ... their 503A compounding pharmacy located in Ocala, Florida. , Meeting the Needs ... throughout the United States for high-quality human anti-aging and wellness compounded medications, ...
(Date:1/19/2017)... ... 19, 2017 , ... LabRoots , the leading provider ... world, announces the launch of its newly redesigned website. The sleek new design ... and trending news, vital information on upcoming virtual events and webinars, all while ...
(Date:1/19/2017)... ... 19, 2017 , ... Cosmetic Town, an online plastic surgery community, begins 2017 ... it easier for their readers to get the information they desire. The procedures are ... the techniques used on those particular areas. , “We are excited to streamline our ...
(Date:1/19/2017)... ... January 19, 2017 , ... ... the American Board of Dermatology and fellowship trained Mohs and cosmetic surgeon. After ... of Health, Dr. Li completed his internship in internal medicine at the Emory ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... -- The Global Therapy Partnering Terms and Agreements since ... and agreements entered into by the world,s leading healthcare ... deals by value - Deals listed by company A-Z, ... report provides understanding and access to the partnering deals ... companies. The report provides an analysis of partnering ...
(Date:1/19/2017)... 2017 The drug delivery technology market is ... USD 1,179.20 billion in 2016, at a CAGR of ... chronic diseases, increasing demand for biologics, technological advancements, and ... of this market. Whereas, self-administration & home care and ... growth opportunities for players operating in this market. On ...
(Date:1/18/2017)... , Jan. 18, 2017  EnteroMedics Inc. ... medical devices using neuroblocking technology to treat obesity, ... the pricing of an underwritten public offering of ... to deducting underwriting discounts and commissions and offering ... is comprised of Class A Units, priced at ...
Breaking Medicine Technology: