Navigation Links
PSA screening cuts deaths by 20 percent
Date:3/18/2009

Screening for prostate cancer can reduce deaths by 20%, according to the results of the European Randomized Study of Screening for Prostate Cancer (ERSPC) published online 1700 hours CET, today 18 March (NEJM, Online First*). ERSPC is the world's largest prostate cancer screening study and provides robust, independently audited evidence, for the first time, of the effect of screening on prostate cancer mortality.

The study commenced in the early 1990s involving eight countries Belgium, Finland, France, Italy, Netherlands, Spain, Sweden and Switzerland - with an overall follow-up of up to 12 years. Participants totalled 182,000 but then narrowed down to 162,000 men in seven countries, aged 55-69; only those who had not been screened could take part. The findings are being unveiled at the 24th Annual Congress of the European Association of Urology (EAU) in Stockholm, Sweden (17 - 21 March 2009).

By initially screening men 55 to 69 years with the PSA marker and offering regular follow up, this led to an increase in early detection. Deaths due to metastasized disease were then reduced. Exact data showed that on average for every 1,408 men screened, 48 had cancer diagnosed and received treatment, resulting in saving one life. Screening took place on average every four years with a mean follow-up over nine years. The cut-off value was a PSA level of 3.0 ng/ml or more. Men with this reading were then offered a biopsy.

Prof Fritz Schrder, international coordinator of the ERSPC study explained: "The study shows that PSA screening delivers a 20% reduction in mortality from prostate cancer. This provides decision makers on screening policies with important new data on the effectiveness of PSA testing in preventing deaths."

"However, the ERSPC is also near to completing additional studies on quality of life and cost-effectiveness and these must be assessed before making a decision about the appropriateness of a national prostate screening policy."

Worldwide, prostate cancer is the second leading cause of cancer death. Separate ERSPC findings already confirm that approximately 30% of detected cancers actually have non-aggressive features and are 'indolent' or slow growing. This overdiagnosis is an unavoidable effect from all cancer screening procedures. With prostate cancer, a new, more conservative form of monitoring, 'Active Surveillance', might be an important method to help avoid early invasive treatment.


'/>"/>

Contact: Lindy Brouwer
l.brouwer@uroweb.org
European Association of Urology
Source:Eurekalert

Related medicine news :

1. 2 Studies Conflict Over Value of Prostate Cancer Screening
2. Cancer Screening Tests Could Do More Harm Than Good: Readers Digest April Cover Story
3. Understand Colon Cancer with MyBiopsy.Org; Schedule a Screening Test at MyHealthTestReminder.Org
4. New Data Reveals That Gaps in Coverage for Those With Private Insurance Are Major Barriers to Colorectal Cancer Screening
5. March is National Colorectal Cancer Awareness Month: Do You Know What Your Screening Options Are?
6. HealthYes! Now Offering its Preventive Health Screening Services in Houston
7. ForteBio Launches New Biosensor for Kinetic Analysis and Screening of Human IgG Antibodies
8. Taking Action Together Aims to Increase Screenings and Offer Education to People with Diabetes Living in the Inland Empire
9. Economy could reduce colorectal cancer screening rate
10. Inexpensive depression screening tool works in resource poor countries
11. Mail and electronic reminders may increase colon cancer screening
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2017)... ... June 26, 2017 , ... ... leakage is revolutionizing the way women look and feel about themselves and their ... of female sexual dysfunction and urinary leakage head on with a ground breaking ...
(Date:6/25/2017)... ... 2017 , ... FCPX LUT Vintage Volume 2 for Final Cut Pro X ... Volume 2 contains 60 different color-grade presets, giving editors multiple options for adding different ... single out subjects, plus much more. FCPX LUT Vintage Volume 2 is designed for ...
(Date:6/25/2017)... CA (PRWEB) , ... June 25, 2017 , ... With a heatwave currently bearing down ... or hanging out at the pool. Being swimsuit ready is easy with laser hair removal. ... and repeat again can be a burdensome routine when all you want to do is ...
(Date:6/24/2017)... (PRWEB) , ... June 24, 2017 , ... The weather ... spend time outdoors. Home and business owners should be aware that the summer months ... lake. In fact, mechanical locks and keys can be negatively affected from direct exposure ...
(Date:6/23/2017)... (PRWEB) , ... June 23, 2017 , ... ... Reconciliation Act (BCRA), their proposed healthcare bill to repeal and replace the Affordable ... the Senate bill would make significant cuts to Medicaid, a public health insurance ...
Breaking Medicine News(10 mins):
(Date:6/1/2017)... Pa. , June 1, 2017 Nutriceutical ... and Veterinarian Recommended Solutions (VRS), and KD Pharma Group ... in Nutriceutical Holdings by KD Pharma Group. KD Pharma ... with the option to acquire the entire company. ... in KD. They are committed to growing the NH ...
(Date:5/29/2017)... AVIV, Israel, May 29, 2017  Cellect Biotechnology Ltd. ... innovative technology which enables the functional selection of stem ... results for the first quarter ended March 31 st ... with our accomplishments in the first quarter of 2017," ... first quarter, we announced the treatment of the first ...
(Date:5/23/2017)... 2017  Leaf Healthcare, recognized for developing one ... pressure ulcer prevention, will unveil its comprehensive mobility ... Care Nurses, National Teaching Institute and Critical Care ... Leaf Patient Monitoring System is the first mobility ... The system seamlessly tracks patient movement throughout the ...
Breaking Medicine Technology: