Navigation Links
PSA Reading Could Predict Post-Radiation Survival
Date:11/4/2009

Rising level in prostate cancer patients may call for more treatment, study finds

WEDNESDAY, Nov. 4 (HealthDay News) -- Prostate cancer patients whose prostate-specific antigen (PSA) levels rise within 18 months after radiotherapy have an increased risk of death, say U.S. researchers.

Their study included more than 2,100 patients with clinically localized prostate cancer who experienced biochemical failure (lowest PSA level plus 2 nanograms per milliliter) after treatment. The median interval between treatment and biochemical failure was 35.2 months, but 19 percent of patients developed biochemical failure at 18 months or less.

Five-year, cancer-specific survival for patients who developed biochemical failure within 18 months was 69.5 percent, compared with 89.8 percent for those who developed biochemical failure more than 18 months after treatment.

The study was to be presented Wednesday at the annual meeting of the American Society for Radiation Oncology in Chicago.

"PSA is the gold standard for following prostate cancer patients after they receive radiation or surgery. But we haven't known if having PSA rise sooner means a patient has a greater danger of dying of prostate cancer, though it seems logical," study leader Dr. Mark K. Buyyounouski, a radiation oncologist at the Fox Chase Cancer Center in Philadelphia, said in a news release from the center.

"Now we can use the simple criteria from this study, which is widely available for anyone who has PSA testing, to identify men who have a greater than 25 percent chance of dying from prostate cancer in the next five years. That is huge. There is nothing else that can do that."

Currently, biochemical failure alone doesn't prompt treatment. Doctors usually wait until a patient's PSA reaches a high level or there is some other evidence of tumor spread.

This study suggests that treatment can begin "far sooner without waiting for other signs or symptoms of prostate cancer," Buyyounouski said. "If a patient has biochemical failure at 16 months, rather than wait and learn later that the PSA is rising sharply and risk the development of distant metastasis, therapy can be started sooner based on the increased risk of death."

More information

The American Cancer Society has more about prostate cancer.



-- Robert Preidt



SOURCE: Fox Chase Cancer Center, news release, Nov. 4, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. HCV and HBV spreading more slowly among injection drug users in San Francisco
2. ClassMate Reader - Portable reading system supports K-12 students with reading difficulties
3. Sound training rewires dyslexic childrens brains for reading
4. Diagnostic Mammogram Readings Vary by Radiologist
5. VA Salutes Volunteers Spreading Holiday Cheer
6. Optimal Readings Appoints Operations Veteran Rita Edwards as SVP Clinical Operations
7. Optimal Readings Selected to Present at CEDs 25th Annual Venture Conference
8. New CDC Study Shows Smoke-Free Laws Spreading Across U.S. and Should Spur Remaining States to Take Action
9. Who Knew You Could Learn to Lose Weight by Reading an Enjoyable Novel?
10. Formula Puts Doctor, Patient Glucose Readings on Same Page
11. ECG Reading May Predict Death, Rehospitalization Risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/26/2017)... ... May 26, 2017 , ... “THE FLINTHILLS FAMILY-Our Journey to the Cross”: the personal ... to the Cross” is the creation of published authors, Bob and Margaret Massey. Bob ... say, he is "panther quick and leather tough." His love for others is apparent ...
(Date:5/26/2017)... ... ... Water damage to the flooring of several classrooms at The Fort Lee Elementary ... number of critical issues to address before students could return to classes. , First, ... no disruption to class schedules. Second, the project had to comply with New Jersey ...
(Date:5/24/2017)... ... May 24, 2017 , ... Altec Products, Inc., ... nVerge 2017 – a one-day technology conference in San Diego, CA. , At ... allows users to fully utilize and enhance their Sage ERP solutions by providing improved ...
(Date:5/24/2017)... ... ... Patients who want to receive cosmetic dentistry procedures such as Invisalign® or ... a consultation, with or without a referral. Dr. Bedich enjoys improving the appearance of ... Dr. Bedich offers a variety of cosmetic dentistry services at his practice that are ...
(Date:5/24/2017)... ... May 24, 2017 , ... ... which the endometrial lining of the uterus spreads into the pelvic cavity, ... painful intercourse, painful periods, pelvic pain, or irregular bleeding may have Endometriosis. ...
Breaking Medicine News(10 mins):
(Date:5/6/2017)... -- May is Stroke Awareness Month and Omron Healthcare is ... to prevent a stroke: monitor and manage your blood ... Prevention, undetected and uncontrolled hypertension is a leading risk ... in personal heart health technology, recently evolved its mission ... stroke and is advancing a national public education effort ...
(Date:5/4/2017)... , May 4, 2017 Clarius ... its wireless, handheld ultrasound scanners this week at ... Scientific Meeting (ACOG) in San Diego, ... "Clarius is the perfect tool for ... and heart rate, and evaluate pregnancy-related complications like ...
(Date:5/4/2017)...   BioLife Solutions , Inc. (NASDAQ: ... proprietary clinical grade hypothermic storage and ... announced that the Company,s first quarter 2017 financial results ... 11, 2017, and that the Company will host a ... that afternoon. Management will provide an overview of the ...
Breaking Medicine Technology: