(in thousands, except per share amounts)
(unaudited)
Three Months Ended Twelve Months Ended
December 31, December 31,
2007 2006 2007 2006
Net revenue:
Development $334,947 $291,119 $1,275,399 $1,113,106
Discovery Sciences 6,402 5,238 19,979 33,193
Reimbursed out-of-pockets 33,700 29,855 119,087 101,383
Total net revenue 375,049 326,212 1,414,465 1,247,682
Direct costs:
Development 169,251 147,259 641,902 559,819
Discovery Sciences 3,015 2,431 10,610 9,324
Reimbursable out-of-pocket
expenses 33,700 29,855 119,087 101,383
Total direct costs 205,966 179,545 771,599 670,526
Research and development 5,017 1,577 19,238 5,406
Selling, general and
administrative 93,039 74,129 338,055 304,035
Depreciation and amortization 15,028 12,940 55,592 47,738
Income from operations 55,999 58,021 229,981 219,977
Impairment of equity
investments (690) - (690) -
Other income, net 5,864 4,270 18,662 15,528
Income before income taxes 61,173 62,291 247,953 235,505
Income tax expense 20,646 20,712 84,552 78,853
Net income $40,527 $41,579 $163,401 $156,652
Net income per share:
Basic $0.34 $0.35 $1.38 $1.34
Diluted
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