Navigation Links
PMH clinicians map group at high risk for aggressive, 'hidden' prostate cancer

Clinical researchers at Princess Margaret Hospital (PMH) can now answer the question that baffles many clinicians why do some men with elevated prostate specific antigen (PSA) levels who are carefully monitored and undergo repeated negative biopsies still develop aggressive prostate cancer?

The answer is hidden tumours located on the top of the prostate that evade traditional diagnostic procedures, including ultrasound-guided needle biopsy. The PMH research, published online today in the British Journal of Urology International (BJU 8938), demonstrates that magnetic resonance imaging (MRI) is the best tool to reveal such tumours.

"Our findings identify a specific high-risk group whose tumours are difficult to diagnose because of location. These men benefit from MRI, which guides the biopsy procedure with a high degree of accuracy," says author Dr. Nathan Lawrentschuk, Urologic Oncology Fellow, PMH Cancer Program, University Health Network. "The research team calls the clinical presentation of elevated PSA and repeated negative biopsy results in 'prostate evasive anterior tumour syndrome' (PEATS)."

"Knowing about PEATS may also be important for men already on 'active surveillance' patients with slow-growing prostate cancer who are being regularly monitored through PSA testing and biopsy. Every man does not need an MRI, but knowing about PEATS will help us identify those who do," says principal investigator Dr. Neil Fleshner, Head of the Division of Urology, Princess Margaret Hospital, Professor of Surgery at University of Toronto, and Love Chair in Prostate Cancer Prevention Research.

A team of urologists, surgeons, radiologists and pathologists studied 31 PMH patients who had positive biopsy results and tumours on top of their prostate as shown on MRI. They found that MRI was able to help diagnose hidden prostate tumours 87% of the time.

Dr. Lawrentschuk says clinicians need to be aware of PEATS because these hidden tumours can be aggressive.


Contact: Jane Finlayson
University Health Network

Related medicine news :

1. Training clinicians helps reduce rates of early childhood cavities
2. Florida Clinicians Now Delivering Non-Invasive Image-Guided Treatments Using Novalis Tx(TM) Radiosurgery Technology
3. HIV-Treating Clinicians Support Health Care Reform, Express Caution
4. National Coalition of Front-Line Skilled Nursing Clinicians: Bipartisan Momentum to Stop CMS Medicare Regulation, Subsequent Funding Cuts, Grows in Congress
5. Materials and Processes for Medical Devices Event Brings Clinicians, Engineers, Designers Together
6. Polycom and AMD Global Telemedicine Inc. To Deliver Integrated Visual And Voice Telehealth Capability To Clinicians On-The-Go
7. Study finds virtual doctors visits satisfactory for both patients and clinicians
8. Practicing Clinicians Exchange Forms Partnership With Restless Legs Syndrome Foundation
9. Educating referring clinicians about advanced imaging leads to drop in imaging exams
10. Alarming Rise in Autism Brings Hundreds of Parents, Researchers and Clinicians Together from Around the World to Atlanta April 17-19, 2009
11. Enloe Medical Center Partners with Carefx to Help Clinicians Quickly, Easily Access Diverse Patient Information
Post Your Comments:
(Date:11/24/2015)... Dallas, Texas (PRWEB) , ... November 24, 2015 , ... ... of all charitable donations are made in the last five weeks of the year ... #GivingTuesday was created in 2012 to connect the nation’s charities with those individuals who ...
(Date:11/24/2015)... ... November 24, 2015 , ... In an article ... and variables that determine which patients are or are not eligible for bariatric surgery. ... a BMI over 40, are more than 100 pounds overweight, or have a BMI ...
(Date:11/24/2015)... (PRWEB) , ... November 24, 2015 , ... DMG Productions ... Ed Begley Jr., airing first quarter 2016 via Discovery Channel. Dates and show times ... the Province, and is in the business of producing and supplying medical marijuana pursuant ...
(Date:11/24/2015)... Church, VA (PRWEB) , ... November 24, 2015 , ... ... — 1:30 p.m. – 3:00 p.m. EST, , FDA has long ... regulations. CLIA regulations apply to performing the tests and do not meet the device ...
(Date:11/24/2015)... ... November 24, 2015 , ... The Trustees, ... paid entry and parking fees at several of their most popular properties, including ... Barrington in support of REI’s Black Friday #OptOutside Campaign. The Trustees encourage families ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... , Nov. 24, 2015  Natera, Inc. ... non-invasive genetic testing and the analysis of ... will present at the 27 th  Annual ... 2, 2015 at 1:00 p.m. ET.  Matthew Rabinowitz, Ph.D., CEO ... results, business activities and financial outlook. ...
(Date:11/24/2015)... New York , 24. November 2015 ... des Avery Breathing Pacemaker Systems, ist erfreut, ... als Clinical Consultant bekannt geben zu können. ...   --> Foto ... Stockholm (Schweden). Von 1984-1986 war ...
(Date:11/24/2015)... , Nov. 24, 2015   HeartWare International, ... of less-invasive, miniaturized circulatory support technologies that are revolutionizing ... President and Chief Executive Officer Doug Godshall ... th Annual Healthcare Conference on December 1, 2015 ... December 1-2 in New York . ...
Breaking Medicine Technology: