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PLC Systems Updates Common Stock Listing Status
Date:11/12/2008

FRANKLIN, Mass., Nov. 12 /PRNewswire-FirstCall/ -- PLC Systems Inc. (Pink Sheets: PLCSF), a company focused on innovative cardiac and vascular medical device-based technologies, today stated that, following the delisting of its common stock from NYSE Alternext (formerly known as the American Stock Exchange) on Monday, November 10, 2008, the company is working to secure the intended transfer of its common stock listing to the OTCBB. Until that listing is accomplished, the company's common stock is trading on the Pink Sheets, and information can be found at http://www.pinksheets.com under the symbol "PLCSF". When the transfer to OTCBB is completed, the company will announce the new trading symbol on that market.

About PLC Systems Inc.

PLC Systems Inc. is a medical technology company specializing in innovative technologies for the cardiac and vascular markets.

PLC's newest product, RenalGuard, is approved for sale in the EU as a general fluid balancing device. The RenalGuard System consists of a unique, proprietary, closed loop, software-controlled console and accompanying single- use sets that can be used by physicians and nurses to balance patient fluid levels during a variety of medical procedures. With its automated matched fluid replacement capability, RenalGuard is intended to minimize the risk to patients of over- or under-hydration while also largely eliminating what can be an intensive and time consuming manual fluid balancing task for physicians and nurses.

Headquartered in Franklin, Massachusetts, PLC pioneered the CO2 Heart Laser System, which cardiac surgeons use to perform CO2 transmyocardial revascularization (TMR) to alleviate symptoms of severe angina. CO2 TMR offers a treatment option for angina patients who suffer from severe coronary artery disease. The CO2 Heart Laser is the world's first TMR angina relief device cleared for commercial distribution by both the U.S. Food and Drug Administration and Japanese Ministry of Health, Labor and Welfare, and to obtain a CE Mark for distribution within the EU.

Additional company information can be found at http://www.plcmed.com.

This press release contains "forward-looking" statements. For this purpose, any statements contained in this press release that relate to prospective events or developments are deemed to be forward-looking statements. Words such as "believes," "anticipates," "plans," "expects," "will" and similar expressions are intended to identify forward-looking statements. Our statements of our objectives are also forward-looking statements. While we may elect to update forward-looking statements in the future, we specifically disclaim any obligation to do so, even if our estimates change, and you should not rely on these forward-looking statements as representing our views as of any date subsequent to the date of this press release. Actual results could differ materially from those indicated by such forward-looking statements as a result of a variety of important factors, including that our stock may not be accepted for trading on the OTCBB, and additional risk factors described in our Quarterly Report on Form 10-Q for the quarter ended June 30, 2008, and our other SEC reports.

PLC Systems, PLC Medical Systems, PLC and CO2 Heart Laser, and RenalGuard are trademarks of PLC Systems Inc.

Contact: Mary T. Conway

Conway Communications

617-244-9682

mtconway@att.net


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SOURCE PLC Systems Inc.
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