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PET predicts outcomes for patients with cervical spinal cord compression
Date:9/4/2013

ost-operatively, those with myelopathy type 1 had a marked decrease in 18F-FDG uptake, while myelopathy type 2 patients had only a moderate decline in uptake.

The overall outcome in myelopathy type 1 patients was favorable, and the patients showed significant improvement on their functional status assessment. In contrast, there was no significant clinical change in patients with inconspicuous 18F-FDG uptake.

"A hypermetabolism of the cervical spinal cord at the level of cervical spine stenosis as indicated by a locally increased 18F-FDG uptake seems to be a marker for a potentially reversible phase of a compression-induced cervical myelopathy," explained Galldiks. "The lesion of the spinal cord seems to be predominantly functional. Presence of this metabolic pattern reflects the time frame when decompressive surgery can lead to substantial clinical improvement. In order to stratify eligible patients for decompressive surgery, our findings may help to implement 18F-FDG PET investigations of the cervical spine in clinical routine."


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Contact: Susan Martonik
smartonik@snmmi.org
703-652-6773
Society of Nuclear Medicine
Source:Eurekalert

Page: 1 2

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