Navigation Links
PET imaging response a prognostic factor after thoracic radiation therapy for lung cancer
Date:11/6/2009

(PHILADELPHIA) A rapid decline in metabolic activity on a PET scan after radiation therapy for non-small cell lung cancer is correlated with good local tumor control, according to a study presented by researchers at Thomas Jefferson University Hospital at the 51st ASTRO Annual Meeting.

In addition, the researchers also found that the higher the metabolic activity and tumor size on a PET scan before treatment, the more likely a patient is to die from lung cancer.

"PET scanning is an emerging tool of molecular imaging in lung cancer, in contrast to CT scans and MRI scans which are anatomic imaging," said Maria Werner-Wasik, associate professor of Radiation Oncology at Jefferson Medical College of Thomas Jefferson University, and the study's lead author. "It has become an important tool in the evaluation of lung cancer staging and evaluation of treatment response."

Dr. Werner-Wasik and colleagues conducted a retrospective analysis of 50 patients with lung cancer who received PET imaging before and after radiation therapy. They analyzed the prognostic factors for tumor local failure. They measured the metabolic activity using the maximum Standardized Uptake Value (mSUV). They also measured the tumor size, or the Metabolic Tumor Volume.

The risk of local failure decreased for each unit decline in mSUV by the first post-therapy scan. When compared to the pre-therapy PET scan, the mSUV of the primary tumor declined by 72 percent in the by the first post-therapy scan, 76 percent by the second scan and 77 percent by the third scan. Nineteen patients achieved a metabolic complete response at the median time of 10.6 months. Eight patients suffered local failure. Other factors significantly associated with increased local failure included female gender, stage IV disease and large tumor size.


'/>"/>

Contact: Emily Shafer
emily.shafer@jefferson.edu
215-955-6300
Thomas Jefferson University
Source:Eurekalert

Page: 1

Related medicine news :

1. Imaging cuts in Medicare fee schedule: An access catastrophe and danger to patients
2. Emerging imaging modalities impact diagnosis of digestive disease
3. Ziosoft Announces Agreement with Imaging & Medical Information Technology to Distribute Ziosoft's 3D Advanced Visualization Software in Turkey
4. Bioluminescence imaging used for eye cancer detection
5. Versus Technology Provides Real-Time Patient Flow and Volume Management to Eastern Maine Medical Centers New Imaging Center
6. Ziosoft and Global Imaging Online Announce Reseller Agreement for France and Maghreb Area
7. Meeting highlights the role of molecular imaging biomarkers in clinical research and therapeutics
8. Molecular imaging holds promise for early intervention in common uterine cancer
9. A potential new imaging agent for early diagnosis of most serious skin cancer
10. Coronary imaging techniques helps to identify plaques likely to cause heart attacks
11. Results From Landmark PROSPECT Trial Demonstrate the Ability of Volcanos VH(R) IVUS Imaging to Identify Plaques Most Likely to Cause Heart Attacks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... Vegas, Nevada (PRWEB) , ... October 13, 2017 , ... ... 7® Hemp CBD Oil utilizing Purzorb™ technology. Applying the Purzorb™process to full spectrum CBD ... dose required and providing a CBD form that can be easily incorporated into liquid ...
(Date:10/13/2017)... ... , ... Apple Rehab Shelton Lakes , which specializes in the delivery ... as part of a disaster drill on October 3rd. , Apple Rehab participated with ... Manager, as well as the Connecticut Long Term Care Mutual Aid Plan (LTC-MAP). ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network for professional ... action towards gender equality at their inaugural Summit in New York City in June. ... a social audience of over 3 million. To watch the Mobilize Women video, ...
(Date:10/13/2017)... ... ... Talented host, actor Rob Lowe, is introducing a segment ... of "Success Files," which is an award-winning educational program broadcasted on PBS Member ... with passion and integrity. , Sciatica occurs when the sciatic nerve in the ...
(Date:10/13/2017)... ... , ... “America On The Brink”: the Christian history of the United States ... creation of published author, William Nowers. Captain Nowers and his wife, Millie, have ... thirty years in the Navy. Following his career as a naval aviator and ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... Oct. 2, 2017 Diplomat Pharmacy, Inc. (NYSE: ... Software and Consulting, LLC , and named its founder ... based in Tennessee , will operate ... expands EnvoyHealth,s service offerings for health care partners to ... "In an interoperable world, technology ...
(Date:9/28/2017)... , Sept. 28, 2017 Hill-Rom Holdings, ... 2017 earnings conference call and webcast on Friday, November ... a.m. (EDT) and ending at approximately 8:30 a.m. (CDT) ... discussing the company,s 2017 financial performance and guidance for ... opportunities, initiatives to enhance operational performance, and long-range financial ...
(Date:9/25/2017)... R.I. , Sept. 25, 2017  EpiVax, ... assessment, vaccine design, and immune-engineering today announced the ... on the development of personalized therapeutic cancer vaccines. ... has provided exclusive access to enabling technologies to ... Eng., MBA will lead EpiVax Oncology as Chief ...
Breaking Medicine Technology: