Navigation Links
PET/CT bests gold standard bone marrow biopsy for diagnosis and prognosis of lymphoma patients
Date:8/1/2013

Reston, Va. A more precise method for determining bone marrow involvement in patients with diffuse large B-cell lymphoma (DLBCL)a key factor in tailoring patient management planshas been identified by researchers in a study published in the August issue of The Journal of Nuclear Medicine. Imaging with 18F-FDG positron emission tomography/computed tomography (PET/CT), when compared to bone marrow biopsy, was more sensitive, showed a higher negative predictive value and was more accurate, changing treatment for 42 percent of patients with bone marrow involvement.

DLBCL is the most frequent subtype of high-grade non-Hodgkin lymphoma, accounting for nearly 30 percent of all newly diagnosed cases in the United States. In recent decades, there has been a 150 percent increase in incidence of DLBCL.

"In our study, we showed that in diffuse large B-cell lymphoma, 18F-FDG PET/CT has better diagnostic performance than bone marrow biopsy to detect bone marrow involvement and provides a better prognostic stratification. While bone marrow biopsy is considered the gold standard to evaluate bone marrow involvement by high-grade lymphomas, 18F-FDG PET/CT is in fact the best method to evaluate extension of the disease, as well as avoid invasive procedures," said Louis Berthet, MD, lead author of the study "In Newly Diagnosed Diffuse Large B-Cell Lymphoma, Determination of Bone Marrow Involvement with 18F-FDG PET/CT Provides Better Diagnostic Performance and Prognostic Stratification Than Dose Biopsy."

The retrospective study included 133 patients diagnosed with DLBCL. All patients received both a whole-body 18F-FDG PET/CT scan, as well as a bone marrow biopsy to determine bone marrow involvement. A final diagnosis of bone marrow involvement was made if the biopsy was positive, or if the positive PET/CT scan was confirmed by a guided biopsy, by targeted magnetic resonance imaging (MRI) or, after chemotherapy, by the concomitant disappearance of f
'/>"/>

Contact: Susan Martonik
smartonik@snmmi.org
703-652-6773
Society of Nuclear Medicine
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Study examines necessity of additional imaging in PET/CT oncologic reports
2. Benefit of PET and PET/CT in ovarian cancer is not proven
3. Pretreatment PET/CT imaging of lymph nodes predicts recurrence in breast cancer patients
4. Benefit of PET or PET/CT in recurrent bowel cancer is not proven
5. PET/CT shows clear advantages over conventional staging for breast cancer patients
6. Inflammatory bowel disease detection enhanced with PET/CT
7. Heart: Cardiac PET/MR measures up to PET/CT
8. U.S. Bests Canada, Europe in Drug Approvals
9. Bestselling Author Hellen Chen Talked About the Pitfalls of Dating and What is Causing Marriages to Fail in Recent Workshops
10. Holistic Family Doctor Authors Amazon Bestselling Book in Response to ObamaCare
11. NY Times Bestselling Author Dr. Eben Alexander to Speak at Sofia University
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/5/2015)... Wimbledon Health Partners , the leading ... and NCV testing, announced the addition of Bradley ... Dr. Artel will be responsible for medical oversight of ... and the continued growth and support of Wimbledon U. ... Health Partners as a consulting physician since inception. I’m ...
(Date:3/5/2015)... Chicago, IL (PRWEB) March 05, 2015 ... to announce their sponsorship of the upcoming Crain’s Chicago ... , The Physicians' Breakfast will take place from ... 160 East Pearson Street, Chicago, IL 60611. The morning’s ... of Chicago’s top healthcare professionals. , The panel ...
(Date:3/5/2015)... 2015 Altec Products, Inc., a leader ... their participation in the Houston, TX and Charlotte, NC ... Tour will unite Sage enterprise resource planning (ERP) software ... solutions to real-world business challenges. , The Houston, ... Houston Galleria Area on March 10th. The Charlotte, NC ...
(Date:3/5/2015)... The recent influx of online diet pills ... more and more internet ads offering “prescription” online diet ... easy for more people to fall prey to gimmicks ... their health. The company urges consumers to ask themselves ... , 1.    Where are the products manufactured and are they ...
(Date:3/5/2015)... March 5, 2015 – As National Patient Safety ... 2015), children’s hospitals around the country are affirming the ... as safe as possible for their children. , A ... Patient Safety (SPS) and the Children’s Hospital Association—are collaborating ... visiting the hospital with their child. , “SPS ...
Breaking Medicine News(10 mins):Health News:Wimbledon Health Partners Appoints Chief Medical Officer to Attain Medicare Market Share 2Health News:Wimbledon Health Partners Appoints Chief Medical Officer to Attain Medicare Market Share 3Health News:Cook County Law Firm to Sponsor Physicians Breakfast 2Health News:Altec Attends Sage Inspire Tour Stops in Houston and Charlotte to Showcase Sage ERP Document Management and Workflow Solution 2Health News:Altec Attends Sage Inspire Tour Stops in Houston and Charlotte to Showcase Sage ERP Document Management and Workflow Solution 3Health News:Diet Doc Announces Four Simple Questions that Dieters Must Ask Prior to Purchasing Online Diet Pills 2Health News:Diet Doc Announces Four Simple Questions that Dieters Must Ask Prior to Purchasing Online Diet Pills 3Health News:Children’s Hospitals Offer Safety Tips for Patient Families During National Patient Safety Awareness Week 2Health News:Children’s Hospitals Offer Safety Tips for Patient Families During National Patient Safety Awareness Week 3Health News:Children’s Hospitals Offer Safety Tips for Patient Families During National Patient Safety Awareness Week 4
... SACRAMENTO, Calif., Aug. 8 With the fall ... to offer low-cost,physical exams at its six Sacramento area ... student-athletes, who are required to have a sports physical,in ... during the entire,month of August. It is not necessary ...
... transmission and the degree to which people are able to ... hope, have been overlooked in policies to tackle HIV/AIDS. ... (ESRC) argues that hope is a powerful tool in the ... years into the AIDS epidemic a medical vaccine for the ...
... Aug. 7 Eastern Insurance,Holdings, Inc. (Nasdaq: ... today that,it has executed a definitive agreement ... ("Employers") in a transaction valued at,approximately $14.9 ... in,debt. Employers, wholly owned subsidiary is Employers ...
... activities fostering total health in ... communities ... and Pasadena,Forward, a Pasadena-based nonprofit organization, today announced that,Kaiser Permanente ... inaugural race, calendared for Sunday, November 16, 2008, is,the flagship ...
... MEXICO CITY, Aug. 7 GlaxoSmithKline (NYSE:,GSK) ... clinical trials found,that anti-HIV regimens containing EPZICOM ... regardless of baseline viral loads.,One of the ... treatment with,regimens containing EPZICOM versus regimens containing ...
... interventions to control body,s attack on its own healthy tissue ... be more responsible for causing autoimmune diseases like lupus or ... , The finding, published in the Aug. 7 online ... a new path to pursue in finding ways to stop ...
Cached Medicine News:Health News:Sutter Express Care Offers Low-Cost Physicals for Student-Athletes 2Health News:Hope: An overlooked tool in the battle against HIV/AIDS 2Health News:Eastern Insurance Holdings, Inc. Announces Definitive Agreement to Acquire Employers Security Holding Company and Subsidiaries 2Health News:Eastern Insurance Holdings, Inc. Announces Definitive Agreement to Acquire Employers Security Holding Company and Subsidiaries 3Health News:Eastern Insurance Holdings, Inc. Announces Definitive Agreement to Acquire Employers Security Holding Company and Subsidiaries 4Health News:Kaiser Permanente Becomes Presenting Sponsor for Pasadena Marathon 2Health News:Analysis of Six Clinical Trials Finds EPZICOM(R) Effective in Treatment-Naive HIV Patients With Both High and Low Baseline Viral Loads 2Health News:Analysis of Six Clinical Trials Finds EPZICOM(R) Effective in Treatment-Naive HIV Patients With Both High and Low Baseline Viral Loads 3Health News:Analysis of Six Clinical Trials Finds EPZICOM(R) Effective in Treatment-Naive HIV Patients With Both High and Low Baseline Viral Loads 4Health News:Analysis of Six Clinical Trials Finds EPZICOM(R) Effective in Treatment-Naive HIV Patients With Both High and Low Baseline Viral Loads 5Health News:Analysis of Six Clinical Trials Finds EPZICOM(R) Effective in Treatment-Naive HIV Patients With Both High and Low Baseline Viral Loads 6
(Date:3/4/2015)... 2015  Hill-Rom Holdings, Inc. (NYSE: HRC ... has been elected to its Board of Directors.  She ... Covidien, as well as President of Covidien,s Vascular Therapies ... from 2010 to 2012. Ms. Enxing Seng ... ev3 Incorporated, where she was a founding member and ...
(Date:3/4/2015)... Diabetes Care®, Inc. (NASDAQ: TNDM ), a medical ... Pumps, today announced the closing of its previously announced underwritten ... price to the public of $11.50 per share, which includes ... to purchase up to an additional 787,500 shares. All of ... BofA Merrill Lynch and Piper Jaffray ...
(Date:3/4/2015)... OAKS, Calif. , March 4, 2015 ... Board of Directors today declared a $0.79 per share ... will be paid on June 5, 2015, to all ... on May 14, 2015.  About Amgen ... for patients suffering from serious illnesses by discovering, developing, ...
Breaking Medicine Technology:Hill-Rom Elects Stacy Enxing Seng to its Board of Directors 2Tandem Diabetes Care Announces Closing of Underwritten Public Offering of Common Stock 2Amgen Announces 2015 Second Quarter Dividend 2Amgen Announces 2015 Second Quarter Dividend 3
... Calif., Sept. 15, 2011 Avanir Pharmaceuticals, Inc. (NASDAQ: ... upcoming investment conferences. The conference schedule is as follows: ... York, NY Tuesday September 20, 2011 11:30 a.m. ET ... St. Regis, New York, NY Tuesday September 27, 2011 ...
... N.J., Sept. 15, 2011 meridianEMR ® , ... Health Records (EHR) for Urology, announces that its ... breach and other unusual activities on a practice,s ... the Urology practice to respond immediately in protecting ...
Cached Medicine Technology:meridianEMR Advanced Monitoring System Catches Security Breach 2meridianEMR Advanced Monitoring System Catches Security Breach 3
... CX5 Delta takes the automation and ... and adds the benefit of electrolyte ... chemistry system for the low- to ... capabilities and continuous sample loading. The ...
... Designed for the high-volume lab, the SYNCHRON ... process- performing up to 2,880 tests per ... of the SYNCHRON LX4201 with broad menu, ... what you've come to expect from Beckman ...
... total of 53 on-board assays, an ... a host of performance-driven features, the ... workstations and automate time-intensive manual processes.The ... Immunoassay system and DL2000* intergrate to ...
The leading fully automated system for plasma protein determinations. Third generation nephelometer combines reliability with highly cost-effective performance....
Medicine Products: