Navigation Links
PCB can increase risk of abdominal fat
Date:5/29/2012

There is a correlation between high levels of the environmental toxin PCB and the distribution of body fat to the abdomen. This is shown in a new study published today in the scientific journal Obesity. Abdominal fat is already known to increase the risk of diabetes and high blood pressure, among other conditions.

Fat inside the abdomen (visceral fat) is considerably more dangerous that fat near the surface of the body (subcutaneous fat). For instance, fat in the abdomen has previously been linked to the development of diabetes. Monica Lind, associate professor in environmental medicine at the Section for Occupational and Environmental Medicine, together with Lars Lind, professor of medicine, has analysed data from the so-called PIVUS study, which comprises more than 1,000 70-year-olds in Uppsala.

From the same material they have previously shown that PCB can predict the development of diabetes. In the present study, these researchers measured levels in the blood of 23 persistent organic environmental toxins in the more than 1,000 70-year-old women and men. In nearly 300 of them, with the aid of magnetic imaging, they also investigated the amount of fat in various parts of the abdomen. Previous studies have used only BMI as a measure of fatness. They found that having high levels of the highly chlorinated and very persistent compound PCB189 was related to a high proportion of fat in the abdomen.

- These findings may indicate that PCB189, which was also related to developing diabetes, may be of significance in how fat is stored in the body, says Monica Lind.

To understand the underlying mechanism, more research is needed in the form of controlled laboratory studies. According to Monica Lind, there are several possible causes. For example, it would be interesting to study whether there is a hormonal impact on fat metabolism, an inhibition of the breakdown of cortisol, or an inhibition of the creation of oestrogen.


'/>"/>

Contact: Monica Lind
Monica.Lind@medsci.uu.se
46-070-320-3066
Uppsala University
Source:Eurekalert

Related medicine news :

1. World Health Assembly endorses new plan to increase global access to vaccines
2. Bend Research increases hot-melt extrusion capacity
3. Canada should significantly increase its funding of randomized clinical trials
4. New initiative aims to increase mobility for disabled children worldwide
5. Antidepressant use associated with increased mortality among critically ill patients?
6. Tuberculosis increases the risk of lung cancer mortality in the elderly
7. Low-dose CT screening may benefit individuals at increased risk for lung cancer
8. Sleep disordered breathing is associated with an increased risk of cancer mortality
9. Dietary supplements increase cancer risk
10. Chemotherapys effect on overall survival seems to increase based on tumor size
11. Reported increase in older adult fall deaths due to improved coding
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/10/2016)... ... February 10, 2016 , ... Ongoing news of the ravages of traumatic brain ... conduct a survey that takes a closer look at cases of TBI being managed ... causes of TBI among the aging population, and identifies the challenges associated with their ...
(Date:2/10/2016)... MI (PRWEB) , ... February 10, 2016 , ... ... Apifiny® across their network of laboratory service centers across the country. Launched ... to aid clinicians in the detection of prostate cancer. Apifiny order volume exceeded 3,000 ...
(Date:2/10/2016)... (PRWEB) , ... February 10, 2016 , ... ... announced that it has been awarded the prestigious Distinguished Emerald Club of the ... program conducted by BoardRoom magazine, one of the most respected trade publications serving ...
(Date:2/10/2016)... ... February 10, 2016 , ... Workrite Ergonomics, who is celebrating ... evolved from humble beginnings to being an internationally recognized leader in their industry. , ... today”, said Charlie Lawrence, President of Workrite. “Workrite recognized the importance of good ...
(Date:2/10/2016)... ... February 09, 2016 , ... ... Face and Body Specialists are delighted to welcome a new addition to their ... Face and Body Specialists as a nurse practitioner performing cosmetic procedures ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... and SAN DIEGO , ... Inc., a global leader in viral gene therapy manufacturing, ... treatments for congestive heart failure and other chronic diseases, ... a scalable manufacturing process and produce cGMP-grade RT-100 (Ad5.hAC6) ... --> --> ...
(Date:2/10/2016)... 2016 Immune Pharmaceuticals Inc. (NASDAQ: IMNP ... it has filed a patent application directed to the ... --> --> The new ... Ceplene (histamine dihydrochloride) in combination with immune checkpoint inhibitors. ... efficacy of Ceplene and IL-2 therapy in patients with ...
(Date:2/10/2016)... Feb. 10, 2016  Oxis International Inc. (OTC/QB: OXIS) ... was described as a "clinical trial triumph" after one ... into complete cancer remission. Daniel Vallera ... Masonic Cancer Center. --> Daniel Vallera ... Masonic Cancer Center. --> An article ...
Breaking Medicine Technology: