Navigation Links
Ozone Breaks Down Lungs' Defenses
Date:10/1/2007

It kills off immune cells that typically fight bacteria, study finds

MONDAY, Oct. 1 (HealthDay News) -- Ozone, a major component of urban air pollution, shuts down early immune responses in the lungs, which in turn makes the lung more vulnerable to bacteria and other foreign invaders, research shows.

It's known that exposure to ozone is associated with increased cardiovascular and pulmonary hospitalizations and deaths, but the actual mechanisms involved haven't been clarified. This study, by Duke University Medical Center pulmonary researchers, may provide some answers.

They found that mice exposed to unhealthy ozone levels showed amplified lung injury in response to bacterial toxins. The rodents also showed increased "programmed cell death" of the type of innate immune system cells that normally devour foreign invaders and keep the airways clear.

The innate immune system -- the most primitive part of the body's defenses -- reacts indiscriminately to any invader.

"Small amounts of inhaled foreign material can be relatively harmless, since they stimulate an appropriate innate immune response that protects the lungs," study lead author and pulmonologist Dr. John Hollingsworth, said in a prepared statement.

"However, it appears that ozone causes the innate immune system to overreact, killing key immune cells, and possibly making the lung more susceptible to subsequent invaders, such as bacteria," he said.

The study is published in the Oct. 1 issue of the Journal of Immunology.

More information

The American Association for Respiratory Care has more about ozone air pollution.



-- Robert Preidt



SOURCE: Duke University, news release, Oct. 1, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Elevated Ozone Levels Hurt Sperm Count
2. Instrument to reveal Information about Ozone Loss
3. Dr Ozones Past Catches up with Him
4. Ozone Treatment - A Good Alternative For Spinal Injury
5. El Ni?o cycles linked to cholera outbreaks
6. Grapes, Melons Implicated in Outbreaks
7. Unhappy relationships could result in more than just heart breaks!
8. SARS outbreaks contained
9. Measles Breaks Out In Kashmir
10. Breaks In The HIV Treatment Resulted In Devastating Results.
11. Task Learning Made Simple By Taking Short Breaks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... PurhealthRX ... CBD Oil utilizing Purzorb™ technology. Applying the Purzorb™process to full spectrum CBD oil will ... and providing a CBD form that can be easily incorporated into liquid products, while ...
(Date:10/13/2017)... ... October 13, 2017 , ... Apple Rehab Shelton Lakes , which ... evacuation of the facility as part of a disaster drill on October 3rd. , ... and Shelton City Emergency Manager, as well as the Connecticut Long Term Care ...
(Date:10/13/2017)... ... 13, 2017 , ... Ellevate Network, the leading network for professional women, brought ... gender equality at their inaugural Summit in New York City in June. The event ... audience of over 3 million. To watch the Mobilize Women video, click here ...
(Date:10/13/2017)... ... , ... Talented host, actor Rob Lowe, is introducing a ... episode of "Success Files," which is an award-winning educational program broadcasted on PBS ... in-depth with passion and integrity. , Sciatica occurs when the sciatic nerve in ...
(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: ... “America On The Brink” is the creation of published author, William Nowers. ... As a WWII veteran, he spent thirty years in the Navy. Following ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)... , Oct. 4, 2017  According to the Centers for Disease ... end of October . PhysicianOne Urgent Care is helping communities across ... Westchester, NY , by offering no-cost* flu shots through the end ... mandated by certain health insurance regulations. ... The best time to get a flu shot is by the end ...
(Date:10/2/2017)... 2017 Diplomat Pharmacy, Inc. (NYSE: ... Consulting, LLC , and named its founder as Diplomat,s ... Tennessee , will operate under Diplomat ... service offerings for health care partners to include IT ... "In an interoperable world, technology delivers comprehensive ...
(Date:10/2/2017)... , Oct. 2, 2017  AllianceRx Walgreens Prime, ... formed by Walgreens and pharmacy benefit manager Prime Therapeutics ... new brand, which included the unveiling of new signage ... , as well as at a few other company-owned ... new brand to patients, some of whom will begin ...
Breaking Medicine Technology: