Navigation Links
Ozone Breaks Down Lungs' Defenses
Date:10/1/2007

It kills off immune cells that typically fight bacteria, study finds

MONDAY, Oct. 1 (HealthDay News) -- Ozone, a major component of urban air pollution, shuts down early immune responses in the lungs, which in turn makes the lung more vulnerable to bacteria and other foreign invaders, research shows.

It's known that exposure to ozone is associated with increased cardiovascular and pulmonary hospitalizations and deaths, but the actual mechanisms involved haven't been clarified. This study, by Duke University Medical Center pulmonary researchers, may provide some answers.

They found that mice exposed to unhealthy ozone levels showed amplified lung injury in response to bacterial toxins. The rodents also showed increased "programmed cell death" of the type of innate immune system cells that normally devour foreign invaders and keep the airways clear.

The innate immune system -- the most primitive part of the body's defenses -- reacts indiscriminately to any invader.

"Small amounts of inhaled foreign material can be relatively harmless, since they stimulate an appropriate innate immune response that protects the lungs," study lead author and pulmonologist Dr. John Hollingsworth, said in a prepared statement.

"However, it appears that ozone causes the innate immune system to overreact, killing key immune cells, and possibly making the lung more susceptible to subsequent invaders, such as bacteria," he said.

The study is published in the Oct. 1 issue of the Journal of Immunology.

More information

The American Association for Respiratory Care has more about ozone air pollution.



-- Robert Preidt



SOURCE: Duke University, news release, Oct. 1, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Elevated Ozone Levels Hurt Sperm Count
2. Instrument to reveal Information about Ozone Loss
3. Dr Ozones Past Catches up with Him
4. Ozone Treatment - A Good Alternative For Spinal Injury
5. El Ni?o cycles linked to cholera outbreaks
6. Grapes, Melons Implicated in Outbreaks
7. Unhappy relationships could result in more than just heart breaks!
8. SARS outbreaks contained
9. Measles Breaks Out In Kashmir
10. Breaks In The HIV Treatment Resulted In Devastating Results.
11. Task Learning Made Simple By Taking Short Breaks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... (PRWEB) , ... June 27, 2016 , ... ... for mental health professionals, announced today its affiliation with Tennessee Counseling Association. ... solutions to the network of the Tennessee Counseling Association, adding exclusive benefits and ...
(Date:6/26/2016)... ... June 27, 2016 , ... Quality metrics are proliferating ... many ways they remain in the eye of the beholder, according to experts who ... of The American Journal of Managed Care. For the full issue, click here ...
(Date:6/26/2016)... ... 26, 2016 , ... Brent Kasmer, a legally blind and certified personal trainer is helping to ... app. The fitness app plans to fix the two major problems leading the fitness industry ... fits all type program , They don’t eliminate all the reasons people quit ...
(Date:6/25/2016)... ... 2016 , ... The temporary closing of Bruton Memorial Library on June 21 due to a ... new, often overlooked aspect of head lice: the parasite’s ability to live away from a ... occurrence, but a necessary one in the event that lice have simply gotten out of ...
(Date:6/25/2016)... ... June 25, 2016 , ... Dr. Calvin Johnson has dedicated ... has implemented orthobiologic procedures as a method for treating his patients. The procedure ... doctors to perform the treatment. Orthobiologics are substances that orthopaedic surgeons use to ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 2016  Astellas today announced the establishment of Astellas Farma Colombia (AFC), a new affiliate with operations headquartered in ... America . ... ... ... ...
(Date:6/23/2016)... , June 23, 2016  Guerbet announced today ... Inc.,s Supplier Horizon Award . One ... Guerbet was recognized for its support of Premier members ... through clinical excellence, and commitment to lower costs. ... receive this recognition of our outstanding customer service from ...
(Date:6/23/2016)... Research and Markets has announced the addition ... States, China, Japan, Brazil, United Kingdom, Germany, France, Italy, ... Surgical Procedure Volumes: Global ... surgical procedure volume data in a geographic context. The ... of growth drivers and inhibitors, including world population growth, ...
Breaking Medicine Technology: