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Oxygenating system associated with lower risk of death for H1N1 patients with respiratory failure
Date:10/5/2011

dy will be available online at http://webtv.esicm.org beginning at 8:45 a.m. CT Wednesday, October 5.

Editorial: Extracorporeal Membrane Oxygenation as a First-Line Treatment Strategy for ARDS

In an accompanying editorial, William Checkley, M.D., Ph.D., of Johns Hopkins University, Baltimore, writes that "the study by Noah et al involving critically ill patients with H1N1 joins other recent investigations that have revitalized interest in the use of ECMO as a treatment strategy for ARDS."

"While underlying risk factors may be different, severe respiratory failure from H1N1 infection presents a clinical challenge similar to that involving ARDS from other causes. Despite several decades of investigation into potential treatment strategies, use of low tidal volumes [volume of air that is drawn in or expelled] remains the only proven therapy to decrease mortality in ARDS. In light of the large observed differences in mortality with and without ECMO, large consortia of trialists may be enticed to consider ECMO as a potential target for a randomized controlled trial early in the course of severe ARDS from all causes."

(doi:10.1001/jama.2011.1504. Available pre-embargo to the media at www.jamamedia.org)

Editor's Note: Please see the article for additional information, including financial disclosures, funding and support, etc.


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Contact: Giles J. Peek, F.R.C.S., (C.Th.), M.D.
giles.peek@uhl-tr.nhs.uk
JAMA and Archives Journals
Source:Eurekalert

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