Navigation Links
Oxygen Treatment May Improve the Odds for Extreme Preemies
Date:12/27/2012

WEDNESDAY, Dec. 26 (HealthDay News) -- Treating very premature infants with high oxygen levels to improve their ability to breathe appears to boost their chances of surviving into toddlerhood, a new U.S. National Institutes of Health study found.

The report is a follow-up to a 2010 study that found higher immediate survival rates among babies who were born between 24 and 27 weeks' gestation who were given high oxygen treatment. That study found that when given highly saturated oxygen (from 91 percent to 95 percent), premature infants fared better than those given relatively low saturated oxygen (from 85 percent to 89 percent).

But concern about long-term survival, as well as a related risk for severe vision impairment, led the research team to continue tracking the infants until they reached the age of 18 months to 22 months after their original due date (the date they would have been born if carried to full term, which is generally considered about 40 weeks' gestation).

Study senior author Dr. Rosemary Higgins, of the pregnancy and perinatology branch of the U.S. National Institute of Child Health and Human Development, said in an institute news release that "higher oxygen targets improve survival and don't appear to threaten survivors' vision in the longer term."

Higgins and her colleagues report the results in the Dec. 27 issue of the New England Journal of Medicine.

To assess the relative benefits of high or low oxygen treatment, the authors focused on toddler survival and developmental status among 1,300 preterm infants who had been born sometime between 2005 and 2009.

The investigators found that 60 percent of all of the preterm infants (regardless of treatment type) showed no signs of either physical or mental impairment as toddlers.

What's more, as a whole, all of the infants seemed to fare comparably well, regardless of treatment approach, when the investigators pooled survival rates and mental and motor development scores.

However, when Higgins and her associates looked more closely at the findings, they noted that high oxygen treatment did specifically translate into higher survival rates.

Importantly, the authors further noted that premature infants who had been offered an adult sleep apnea treatment called "continuous positive airway pressure" (CPAP) fared as well as those who were given a more standard treatment involving a ventilator and lung coating substance (known as surfactant treatment).

"CPAP for infants has been available since the 1970s," explained Higgins. "This is the first study to compare surfactant treatment to CPAP in a large group of infants, and these results reassure us that CPAP is as good a choice in the first hour of life as traditional methods for very preterm babies who need help breathing," she said.

"[But] although these findings can give delivery room practitioners confidence in a suitable approach, they can't help predict how these children will grow or how well they'll do in school," she added. "Our group will continue to monitor the health of a subset of these children through childhood, to determine if there are any major differences between the groups."

More information

For more on premature birth, go to the U.S. National Library of Medicine.

Alan Mozes

SOURCE: U.S. National Institute of Child Health and Human Development, news release, Dec. 26, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Oxygen Deprivation in the Womb May Raise ADHD Risk
2. Study finds association between oxygen deprivation before birth and ADHD
3. Should hyperbaric oxygen therapy be used to treat combat-related mild traumatic brain injury?
4. COPD patients experience poorer sleep quality and lower blood oxygen levels
5. Lack of oxygen in cancer cells leads to growth and metastasis
6. New anti-inflammatory drugs pinch off reactive oxygen species at the source
7. Cooling Helps Oxygen-Deprived Newborns: Study
8. Should oxygen be used for patients with chronic heart failure?
9. Oxygen Therapy Slows Type 1 Diabetes in Mice, Study Says
10. Low oxygen levels could drive cancer growth
11. Central Region of Ghana Infected With Syphilis and HIV According to the HSS Report – VyGone Offers Treatments.
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Oxygen Treatment May Improve the Odds for Extreme Preemies 
(Date:12/5/2016)... ... 2016 , ... For many years, Andrew G. Zubinas has accumulated ... beauty of the Lithuanian language and its poetry inspired him in writing ... lyrically explores all aspects of a living, breathing forest where nothing ever stays the ...
(Date:12/5/2016)... Atlanta, GA (PRWEB) , ... ... ... information technology and security executive networking and relationship-marketing firm, announced today that ... for the 2017 Information Security Executive® (ISE®) Central Awards. , Awards include ...
(Date:12/5/2016)... Novato, CA (PRWEB) , ... December 05, 2016 ... ... company, has extended its partnership with leading global lifestyle design firm kathy ireland® ... , Worldwise® and kathy ireland® Worldwide entered into an exclusive licensing agreement three ...
(Date:12/5/2016)... ... December 05, 2016 , ... Progressive ... of L-Citrulline and glutathione to enhance production of nitric oxide (NO). , NitroGenesis ... shown to produce NO twice as effectively and sustains NO blood levels twice ...
(Date:12/5/2016)... ... December 05, 2016 , ... ... announced that the company will provide alerting technology to Central Illinois Health ... awarded $1.7 million in federal funds as the sole sub-recipient participating with ...
Breaking Medicine News(10 mins):
(Date:12/5/2016)... LAKE OSWEGO, Ore. , Dec. 5, 2016 /PRNewswire/ ... in the BioInsight clinical study. The study evaluates the ... 2 insertion procedure in an office setting. ... ProMRI ® technology that is placed underneath a ... atrial fibrillation and syncope (fainting). Atrial fibrillation is a ...
(Date:12/5/2016)... and Gateway Health proudly announce a dynamic collaboration that will ... members with specific high risk needs. In an ... of consumers, Wellbridge combines technology and population expertise with a ... daily behaviors and lifestyle. ... , , "Dealing ...
(Date:12/5/2016)... PARSIPPANY, N.J. , Dec. 5, ... Sankyo) today announced preliminary safety and efficacy data ... investigational oral selective MDM2 inhibitor, suggesting that DS-3032 ... including relapsed/refractory acute myeloid leukemia (AML) and high-risk ... escalation part of the phase 1 study of DS-3032 ...
Breaking Medicine Technology: