Navigation Links
Oxygen Treatment May Improve the Odds for Extreme Preemies
Date:12/27/2012

WEDNESDAY, Dec. 26 (HealthDay News) -- Treating very premature infants with high oxygen levels to improve their ability to breathe appears to boost their chances of surviving into toddlerhood, a new U.S. National Institutes of Health study found.

The report is a follow-up to a 2010 study that found higher immediate survival rates among babies who were born between 24 and 27 weeks' gestation who were given high oxygen treatment. That study found that when given highly saturated oxygen (from 91 percent to 95 percent), premature infants fared better than those given relatively low saturated oxygen (from 85 percent to 89 percent).

But concern about long-term survival, as well as a related risk for severe vision impairment, led the research team to continue tracking the infants until they reached the age of 18 months to 22 months after their original due date (the date they would have been born if carried to full term, which is generally considered about 40 weeks' gestation).

Study senior author Dr. Rosemary Higgins, of the pregnancy and perinatology branch of the U.S. National Institute of Child Health and Human Development, said in an institute news release that "higher oxygen targets improve survival and don't appear to threaten survivors' vision in the longer term."

Higgins and her colleagues report the results in the Dec. 27 issue of the New England Journal of Medicine.

To assess the relative benefits of high or low oxygen treatment, the authors focused on toddler survival and developmental status among 1,300 preterm infants who had been born sometime between 2005 and 2009.

The investigators found that 60 percent of all of the preterm infants (regardless of treatment type) showed no signs of either physical or mental impairment as toddlers.

What's more, as a whole, all of the infants seemed to fare comparably well, regardless of treatment approach, when the investigators pooled survival rates and mental and motor development scores.

However, when Higgins and her associates looked more closely at the findings, they noted that high oxygen treatment did specifically translate into higher survival rates.

Importantly, the authors further noted that premature infants who had been offered an adult sleep apnea treatment called "continuous positive airway pressure" (CPAP) fared as well as those who were given a more standard treatment involving a ventilator and lung coating substance (known as surfactant treatment).

"CPAP for infants has been available since the 1970s," explained Higgins. "This is the first study to compare surfactant treatment to CPAP in a large group of infants, and these results reassure us that CPAP is as good a choice in the first hour of life as traditional methods for very preterm babies who need help breathing," she said.

"[But] although these findings can give delivery room practitioners confidence in a suitable approach, they can't help predict how these children will grow or how well they'll do in school," she added. "Our group will continue to monitor the health of a subset of these children through childhood, to determine if there are any major differences between the groups."

More information

For more on premature birth, go to the U.S. National Library of Medicine.

Alan Mozes

SOURCE: U.S. National Institute of Child Health and Human Development, news release, Dec. 26, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Oxygen Deprivation in the Womb May Raise ADHD Risk
2. Study finds association between oxygen deprivation before birth and ADHD
3. Should hyperbaric oxygen therapy be used to treat combat-related mild traumatic brain injury?
4. COPD patients experience poorer sleep quality and lower blood oxygen levels
5. Lack of oxygen in cancer cells leads to growth and metastasis
6. New anti-inflammatory drugs pinch off reactive oxygen species at the source
7. Cooling Helps Oxygen-Deprived Newborns: Study
8. Should oxygen be used for patients with chronic heart failure?
9. Oxygen Therapy Slows Type 1 Diabetes in Mice, Study Says
10. Low oxygen levels could drive cancer growth
11. Central Region of Ghana Infected With Syphilis and HIV According to the HSS Report – VyGone Offers Treatments.
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Oxygen Treatment May Improve the Odds for Extreme Preemies 
(Date:10/13/2017)... ... October 13, 2017 , ... Dickinson Insurance and ... and financial preparation services, is providing an update on a charitable event that ... City Rescue is a locally recognized nonprofit that provides shelter and care for ...
(Date:10/13/2017)... IL (PRWEB) , ... October 13, 2017 , ... ... which established the certification process to promote standards of excellence for the field ... Symposium, scheduled for March 22 – 25, 2018 in Orlando, Florida at the ...
(Date:10/13/2017)... ... 13, 2017 , ... Apple Rehab Shelton Lakes , which specializes in ... the facility as part of a disaster drill on October 3rd. , Apple Rehab ... City Emergency Manager, as well as the Connecticut Long Term Care Mutual Aid ...
(Date:10/13/2017)... ... 2017 , ... Global Healthcare Management’s 4th Annual Kids Fun Run brought out ... free event, sponsored by Global Healthcare Management’s CEO, Jon Letko, is aimed at getting ... children of all ages; it is a non-competitive, non-timed event, which is all about ...
(Date:10/13/2017)... ... 2017 , ... “The Journey: From the Mountains to the Mission Field”: the ... in the Philippines. “The Journey: From the Mountains to the Mission Field” is the ... She has taught all ages and currently teaches a class of ladies at her ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... DIEGO , Oct. 12, 2017 AVACEN ... recognized the company with their  2017 New Product Innovation Award ... based on extensive primary and secondary medical device market research ... Medical, through its first-to-market OTC, drug-free pain relief product, the ... unique approach to treating fibromyalgia widespread pain. ...
(Date:10/11/2017)...  True Health, a leader in integrated diagnostics ... National Breast Cancer Awareness month to educate doctors ... Research recently published in ... than 10 million American women are at significant ... BRCA2 and have not had testing. These mutations can ...
(Date:10/5/2017)... Ill. , Oct. 5, 2017  In ... Association of Oral and Maxillofacial Surgeons (AAOMS) released ... opioids – to be used as a first-line ... pain. Recognizing ... the AAOMS White Paper "Opioid Prescribing: Acute and ...
Breaking Medicine Technology: