Navigation Links
Oxygen Treatment May Improve the Odds for Extreme Preemies

WEDNESDAY, Dec. 26 (HealthDay News) -- Treating very premature infants with high oxygen levels to improve their ability to breathe appears to boost their chances of surviving into toddlerhood, a new U.S. National Institutes of Health study found.

The report is a follow-up to a 2010 study that found higher immediate survival rates among babies who were born between 24 and 27 weeks' gestation who were given high oxygen treatment. That study found that when given highly saturated oxygen (from 91 percent to 95 percent), premature infants fared better than those given relatively low saturated oxygen (from 85 percent to 89 percent).

But concern about long-term survival, as well as a related risk for severe vision impairment, led the research team to continue tracking the infants until they reached the age of 18 months to 22 months after their original due date (the date they would have been born if carried to full term, which is generally considered about 40 weeks' gestation).

Study senior author Dr. Rosemary Higgins, of the pregnancy and perinatology branch of the U.S. National Institute of Child Health and Human Development, said in an institute news release that "higher oxygen targets improve survival and don't appear to threaten survivors' vision in the longer term."

Higgins and her colleagues report the results in the Dec. 27 issue of the New England Journal of Medicine.

To assess the relative benefits of high or low oxygen treatment, the authors focused on toddler survival and developmental status among 1,300 preterm infants who had been born sometime between 2005 and 2009.

The investigators found that 60 percent of all of the preterm infants (regardless of treatment type) showed no signs of either physical or mental impairment as toddlers.

What's more, as a whole, all of the infants seemed to fare comparably well, regardless of treatment approach, when the investigators pooled survival rates and mental and motor development scores.

However, when Higgins and her associates looked more closely at the findings, they noted that high oxygen treatment did specifically translate into higher survival rates.

Importantly, the authors further noted that premature infants who had been offered an adult sleep apnea treatment called "continuous positive airway pressure" (CPAP) fared as well as those who were given a more standard treatment involving a ventilator and lung coating substance (known as surfactant treatment).

"CPAP for infants has been available since the 1970s," explained Higgins. "This is the first study to compare surfactant treatment to CPAP in a large group of infants, and these results reassure us that CPAP is as good a choice in the first hour of life as traditional methods for very preterm babies who need help breathing," she said.

"[But] although these findings can give delivery room practitioners confidence in a suitable approach, they can't help predict how these children will grow or how well they'll do in school," she added. "Our group will continue to monitor the health of a subset of these children through childhood, to determine if there are any major differences between the groups."

More information

For more on premature birth, go to the U.S. National Library of Medicine.

Alan Mozes

SOURCE: U.S. National Institute of Child Health and Human Development, news release, Dec. 26, 2012

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Oxygen Deprivation in the Womb May Raise ADHD Risk
2. Study finds association between oxygen deprivation before birth and ADHD
3. Should hyperbaric oxygen therapy be used to treat combat-related mild traumatic brain injury?
4. COPD patients experience poorer sleep quality and lower blood oxygen levels
5. Lack of oxygen in cancer cells leads to growth and metastasis
6. New anti-inflammatory drugs pinch off reactive oxygen species at the source
7. Cooling Helps Oxygen-Deprived Newborns: Study
8. Should oxygen be used for patients with chronic heart failure?
9. Oxygen Therapy Slows Type 1 Diabetes in Mice, Study Says
10. Low oxygen levels could drive cancer growth
11. Central Region of Ghana Infected With Syphilis and HIV According to the HSS Report – VyGone Offers Treatments.
Post Your Comments:
Related Image:
Oxygen Treatment May Improve the Odds for Extreme Preemies 
(Date:11/30/2015)... ... November 30, 2015 , ... A novel class of antimicrobials ... effective in fighting methicillin-resistant Staphylococcus aureus (MRSA), one of the major drug-resistant bacterial ... small molecule analogs that target the functions of SecA, a central part of ...
(Date:11/30/2015)... ... 30, 2015 , ... Using a combination of two blood sugar tests rather ... according to a new study by researchers at the School of Public Health at ... Using Combinations of Blood Glucose Tests ,” published in Frontiers in Public Health, the ...
(Date:11/30/2015)... PA (PRWEB) , ... November 30, 2015 , ... ... to a new study by UPMC and KingMed Diagnostics ... over three years found that consultation with UPMC pathologists resulted in significantly altered ...
(Date:11/30/2015)... ... 30, 2015 , ... The Foundation for Breast and Prostate ... joining forces with the award-winning creator and writer of Downton Abbey Julian Fellowes ... at the Union League of Philadelphia. , The benefit, titled β€œAn Evening ...
(Date:11/30/2015)... , ... November 30, 2015 , ... ... for the last 15 years, announced today that Michigan-based Family Health Center (FHC) ... care for over 45 years, FHC was awarded the largest Affordable Care Act ...
Breaking Medicine News(10 mins):
(Date:11/30/2015)... Diagnostics, the U.S.-based manufacturer of point-of-care biometric testing devices ... systems, and PTS Detect™ cotinine systems, has announced the ... the company into the mHealth market. ... The technology is a system that interfaces with mobile ... and uses test strip technology already developed by PTS ...
(Date:11/30/2015)... and ST. LOUIS , Nov. ... (NASDAQ: ESRX ) today announced an early renewal ... which began in 1999, will now extend through at ... --> After evaluating pharmacy benefit manager capabilities during ... Express Scripts continues to offer the best health plan ...
(Date:11/30/2015)... 30, 2015   Nuance Communications, Inc. (NASDAQ: ... Support Company (NDSC) today jointly announced a new ... that utilize the American College of Radiology,s (ACR) Imaging ... to comply with current and emerging value-based payment ... --> By combining clinical decision support, radiology reporting ...
Breaking Medicine Technology: