Navigation Links
Oxygen Treatment May Improve the Odds for Extreme Preemies
Date:12/27/2012

WEDNESDAY, Dec. 26 (HealthDay News) -- Treating very premature infants with high oxygen levels to improve their ability to breathe appears to boost their chances of surviving into toddlerhood, a new U.S. National Institutes of Health study found.

The report is a follow-up to a 2010 study that found higher immediate survival rates among babies who were born between 24 and 27 weeks' gestation who were given high oxygen treatment. That study found that when given highly saturated oxygen (from 91 percent to 95 percent), premature infants fared better than those given relatively low saturated oxygen (from 85 percent to 89 percent).

But concern about long-term survival, as well as a related risk for severe vision impairment, led the research team to continue tracking the infants until they reached the age of 18 months to 22 months after their original due date (the date they would have been born if carried to full term, which is generally considered about 40 weeks' gestation).

Study senior author Dr. Rosemary Higgins, of the pregnancy and perinatology branch of the U.S. National Institute of Child Health and Human Development, said in an institute news release that "higher oxygen targets improve survival and don't appear to threaten survivors' vision in the longer term."

Higgins and her colleagues report the results in the Dec. 27 issue of the New England Journal of Medicine.

To assess the relative benefits of high or low oxygen treatment, the authors focused on toddler survival and developmental status among 1,300 preterm infants who had been born sometime between 2005 and 2009.

The investigators found that 60 percent of all of the preterm infants (regardless of treatment type) showed no signs of either physical or mental impairment as toddlers.

What's more, as a whole, all of the infants seemed to fare comparably well, regardless of treatment approach, when the investigators pooled survival rates and mental and motor development scores.

However, when Higgins and her associates looked more closely at the findings, they noted that high oxygen treatment did specifically translate into higher survival rates.

Importantly, the authors further noted that premature infants who had been offered an adult sleep apnea treatment called "continuous positive airway pressure" (CPAP) fared as well as those who were given a more standard treatment involving a ventilator and lung coating substance (known as surfactant treatment).

"CPAP for infants has been available since the 1970s," explained Higgins. "This is the first study to compare surfactant treatment to CPAP in a large group of infants, and these results reassure us that CPAP is as good a choice in the first hour of life as traditional methods for very preterm babies who need help breathing," she said.

"[But] although these findings can give delivery room practitioners confidence in a suitable approach, they can't help predict how these children will grow or how well they'll do in school," she added. "Our group will continue to monitor the health of a subset of these children through childhood, to determine if there are any major differences between the groups."

More information

For more on premature birth, go to the U.S. National Library of Medicine.

Alan Mozes

SOURCE: U.S. National Institute of Child Health and Human Development, news release, Dec. 26, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Oxygen Deprivation in the Womb May Raise ADHD Risk
2. Study finds association between oxygen deprivation before birth and ADHD
3. Should hyperbaric oxygen therapy be used to treat combat-related mild traumatic brain injury?
4. COPD patients experience poorer sleep quality and lower blood oxygen levels
5. Lack of oxygen in cancer cells leads to growth and metastasis
6. New anti-inflammatory drugs pinch off reactive oxygen species at the source
7. Cooling Helps Oxygen-Deprived Newborns: Study
8. Should oxygen be used for patients with chronic heart failure?
9. Oxygen Therapy Slows Type 1 Diabetes in Mice, Study Says
10. Low oxygen levels could drive cancer growth
11. Central Region of Ghana Infected With Syphilis and HIV According to the HSS Report – VyGone Offers Treatments.
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Oxygen Treatment May Improve the Odds for Extreme Preemies 
(Date:5/26/2016)... ... May 26, 2016 , ... Despite last week’s media reports hinting at a ... to wait until March 2017 for an interest rate increase, according to Rajeev Dhawan ... Business. , “The Federal Open Market Committee (FOMC) dot charts are of interest to ...
(Date:5/26/2016)... St. Louis, Missouri (PRWEB) , ... May 26, ... ... optimal cost, quality and clinical outcomes, hosted members and suppliers for its inaugural ... with a focus on their mission of elevating the operational health of America’s ...
(Date:5/26/2016)... ... 26, 2016 , ... The Woodlands at John Knox Village , Florida’s ... care for living and healing, celebrated its grand opening, today. The Woodlands at John ... provided by Empowered Staff. , “This is an incredibly fulfilling time for John Knox ...
(Date:5/26/2016)... N.J. (PRWEB) , ... May 26, 2016 , ... ... delivery technologies and development solutions for drugs, biologics, consumer health and global clinical ... sales office in Korea to support the company’s continued investment and strategic growth ...
(Date:5/26/2016)... ... , ... Memorial Day Weekend marks the unofficial start of summer and the ... make sure your family and vehicle are ready to hit the road this weekend. ... deaths and an additional 50,500 serious injuries from motor vehicle crashes during the three-day ...
Breaking Medicine News(10 mins):
(Date:5/25/2016)... , May 25, 2016  Zymo Research Corp. ... their new reference materials that help researchers obtain ... collection to analyses. The rapid growth of the ... researchers to have standard methods to improve the ... Biases inherently exist at every step of the ...
(Date:5/25/2016)... May 25, 2016  Granger Diagnostics today announced immediate ... wounds and infections. This test ensures discovery of ... viruses. The test requires only a simple swab of ... David G. Bostwick , MD, Chief Medical ... wound healing: "We are excited to make available, ...
(Date:5/25/2016)... , May 25, 2016 ... H1 2016"market research report that provides an overview ... comparative analysis at various stages, therapeutics assessment by ... administration (RoA) and molecule type, along with latest ... also reviews key players involved in the therapeutic ...
Breaking Medicine Technology: