Navigation Links
Oxford Nanopore announces licence agreement with Harvard University for graphene DNA sequencing
Date:3/11/2011

11th March 2011, Oxford, UK. Oxford Nanopore Technologies Ltd ("Oxford Nanopore") today announced an exclusive agreement with Harvard University's Office of Technology Development ("Harvard") for the development of graphene for DNA sequencing. Graphene is a robust, single atom thick 'honeycomb' lattice of carbon with high electrical conductivity. These properties make it an ideal material for high resolution, nanopore-based sequencing of single DNA molecules.

Under the terms of the agreement, Oxford Nanopore has exclusive rights to develop and commercialize methods for the use of graphene for the analysis of DNA and RNA, developed in the Harvard laboratories of Professors Jene Golovchenko, Daniel Branton, and Charles Lieber. The agreement adds to an existing collaboration between Oxford Nanopore and Harvard that spans basic methods of nanopore sensing through to the use of solid-state nanopores. Oxford Nanopore will also continue to support fundamental nanopore research at Harvard.

"Graphene is emerging as a wonder material for the 21st century and recent research has shown that it has transformative potential in DNA sequencing." said Dr Gordon Sanghera, CEO of Oxford Nanopore Technologies. "The groundbreaking research at Harvard lays the foundation for the development of a novel solid-state DNA sequencing device. We are proud to partner with the research team that pioneered early nanopore discoveries and continues to break boundaries with new materials and techniques.

"Oxford Nanopore is probably best known for protein nanopores," continued Dr Sanghera. "However, today's agreement highlights that we are increasing our investment in solid-state nanopores by adding graphene to our existing portfolio of solid-state nanopore projects and collaborations."

In a landmark 2010 Nature publication (S. Garaj et al, Nature Vol 467,doi:10.1038/nature09379) the Harvard team and collaborators used graphene to separate two chambers containing ionic solutions, and created a hole - a nanopore in the graphene. The group demonstrated that the graphene nanopore could be used as a trans-electrode, measuring a current flowing through the nanopore between two chambers. The trans-electrode was used to measure variations in the current as a single molecule of DNA was passed through the nanopore. This resulted in a characteristic electrical signal that reflected the size and conformation of the DNA molecule.

At one atom thick, graphene is believed to be the thinnest membrane able to separate two liquid compartments from each other. This is an important characteristic for DNA sequencing; a trans-electrode of this thickness would be suitable for the accurate analysis of individual bases on a DNA polymer as it passes through the graphene.

Nanopore techniques aim to improve substantially the cost, power and complexity of DNA sequencing. While first generation technologies in development at Oxford Nanopore use nanopores made by porous proteins, subsequent generations will use synthetic 'solid-state' materials such as silicon nitride. However, at this time challenges remain in industrial fabrication of synthetic nanopores with the required dimensions and electronic properties. Graphene offers a potential solution due to its strength, dimensions, electrical properties and future potential for low-cost manufacturing.


'/>"/>

Contact: Zoe McDougall
media@nanoporetech.com
44-845-034-7900 x2013
Feinstein Kean Healthcare
Source:Eurekalert  

Related medicine news :

1. Oxford House: Where Stories of Recovery Are Born
2. Lincare Holdings Inc. Announces Fourth Quarter and Year Ended 2009 Financial Results
3. Connecture, Inc. Announces Partnership with MedicareCRM
4. Chiquita Announces Support for School Salad Bar Campaign
5. Team Health Holdings, Inc., Announces Fourth Quarter and Fiscal 2009 Financial Results
6. MDS Announces Agreements to Divest MDS Pharma Services Early Stage Business
7. MyDietShopz.com Announces Biggest Losers Contest - Share Your Story To Inspire Others
8. Rocketboy Media Wins Award for Masonic Lodge Web Site; Announces Signing of Several New Clients
9. Emergency Nurses Association Announces Corporate Sponsors for Leadership Conference
10. Whitemark Homes Inc. Announces Change of Auditors and Additional Corporate Information
11. Sunquest Announces Major Software Updates and Enhancements
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Oxford Nanopore announces licence agreement with Harvard University for graphene DNA sequencing 
(Date:5/26/2016)... , ... May 26, 2016 , ... MadgeTech will be ... engineered, and manufactured in Warner, New Hampshire at the MadgeTech headquarters. With products sold ... monitoring solutions trusted by government agencies, including NASA. , In 2012, NASA strategically ...
(Date:5/26/2016)... ... 26, 2016 , ... An April Gallup survey found rising health care costs ... Sun Health Senior Living (SHSL) may not share those same worries thanks ... copays for the year, while holding the line on increasing their contributions, including premiums, ...
(Date:5/26/2016)... , ... May 26, 2016 , ... ... healthcare supply chain solutions, today announced the organization has earned its ISO 13485 ... standards and is compliant with all rules and policies associated with ISO quality ...
(Date:5/26/2016)... ... May 26, 2016 , ... North Cypress Medical Center hosted ... Club in Cypress. With the help of community partners, the event organizers raised $45,000 ... hope for wounded service members and their families through health, wellness, and therapeutic support. ...
(Date:5/26/2016)... ... ... The MIAMI Institute for Age Management and Intervention celebrates Global Wellness Day with ... Adonis , Wellness Physician of the MIAMI Institute is certified by the American Academy ... , He also heads up FITTLab, the comprehensive medical testing lab located in The ...
Breaking Medicine News(10 mins):
(Date:5/25/2016)... GERMANTOWN, Maryland , May 25, 2016 /PRNewswire/ ... dringenden Bedarf zur Steuerung ... N.V. (NASDAQ: QGEN ; Frankfurt Prime ... Entwicklungsvereinbarung mit Therawis Diagnostics GmbH zur Entwicklung und ... sein. Ein erstes Projekt wird die Entwicklung und ...
(Date:5/25/2016)... , May 25, 2016  Zymo Research Corp. ... their new reference materials that help researchers obtain ... collection to analyses. The rapid growth of the ... researchers to have standard methods to improve the ... Biases inherently exist at every step of the ...
(Date:5/25/2016)... YORK , May 25, 2016 ... Market Size, Share, Development, Growth and Demand Forecast to ... Syringe, Insulin Pump and Others)" published by P&S Market ... at $9,998.3 million in 2015, and it is expected ... Based on type, the insulin pump segment is expected ...
Breaking Medicine Technology: