Navigation Links
Overexpression of Notch1 in temporal lobe epilepsy
Date:5/9/2014

Notch1 signaling can induce astrogliosis in glioma. However, it remains unknown whether Notch1 signaling is involved in the pathogenesis of epilepsy. A recent study by Xijin Liu and co-workers from Huazhong University of Science and Technology in China observed overexpression of Notch1 in the brain tissue of temporal lobe epilepsy rats. After Notch1 regulation, it was relatively effective in reducing seizure frequency and reducing brain discharges, thereby resulting in the ease of seizures to a certain extent. Increased presence of Notch 1 and hairy and enhancer of split-1 was also observed in intractable temporal lobe epilepsy patients. Therefore, Notch signaling may play a role in the pathogenesis of epilepsy in temporal lobe epilepsy and its suppression may provide a new treatment to promote remission in epilepsy. These findings were published in the Neural Regeneration Research (Vol. 9, No. 5, 2014).


'/>"/>

Contact: Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research
Source:Eurekalert  

Page: 1

Related medicine news :

1. Overexpression of proteins 14-3-3 related to chemotherapy resistance
2. MRI can screen patients for Alzheimers disease or frontotemporal lobar degeneration
3. Improved detection of frontotemporal degeneration may aid clinical trial efforts
4. Depression common among children with temporal lobe epilepsy
5. Epilepsy Leads to More Brain Abnormalities Over Time
6. Brain surgery for epilepsy underutilized
7. Response to First Treatment May Predict Epilepsys Course
8. Pediatric epilepsy impacts sleep for the child and parents
9. Parents Often Lose Sleep Over Childs Epilepsy, Study Finds
10. Epilepsy drugs increase risk of fractures and falls
11. Study finds new gene mutations that lead to enlarged brain size, cancer, autism, epilepsy
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Overexpression of Notch1 in temporal lobe epilepsy
(Date:1/20/2017)... (PRWEB) , ... January 20, 2017 , ... Doctor C ... it attended the January ECRM trade show to continue the marketing and distribution of ... C supplement, known for providing 400 percent better absorption than traditional vitamin C supplements. ...
(Date:1/20/2017)... ... January 20, 2017 , ... International Protein, a company based out of ... it attended the January ECRM trade show in Hilton Head, SC. , International ... determined to create a line of products that would elevate her fitness regime. At ...
(Date:1/20/2017)... ... ... “Mary Magdalene: Grace is Greater than Sin”: a unique and memorable piece of ... Magdalene: Grace is Greater than Sin” is the creation of published author, Brenda Roberts, ... who had little knowledge of the female characters portrayed in the Holy Bible. ...
(Date:1/20/2017)... Farmville, NC (PRWEB) , ... January 20, 2017 ... ... the vPEP ® Oscillating Positive Expiratory Pressure (OPEP) device, was featured in ... article by Doug Pursley, MEd, RRT-ACCS, FAARC, “Analysis of Three Oscillating Positive ...
(Date:1/20/2017)... ... ... “The Land of More and More”: a brilliant story for children ... the simple and achievable answer. “The Land of More and More” is the creation ... in Angola, Indiana where he works with the children’s ministry department. , Michael ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... 19, 2017 Incretin Mimetics/GLP-1 Agonists, SNDRIs, Lipase ... The global anti-obesity drugs market is expected to ... the forecast period and CAGR of 38.7% in the second half ... a CAGR of 32.8% from 2016 to 2027. The market is ... $24,063 million in 2027. ...
(Date:1/19/2017)... -- Accuray Incorporated (Nasdaq: ARAY ) announced ... set the bar for excellence in customer satisfaction. The ... rating among radiation treatment delivery systems in the U.S., ... Briefing™. The most recent ratings trend also shows Accuray ... for 11 of the past 12 quarters. ...
(Date:1/19/2017)... LONDON , January 19, 2017 ... Grothey ; European Oncology & Haematology, 2016;12(Suppl 2):3-8; ... ... http://photos.prnewswire.com/prnh/20151014/276718LOGO) Published recently in ... the peer-reviewed journal from touchONCOLOGY, an article by ...
Breaking Medicine Technology: