Navigation Links
Overexpression of Notch1 in temporal lobe epilepsy
Date:5/9/2014

Notch1 signaling can induce astrogliosis in glioma. However, it remains unknown whether Notch1 signaling is involved in the pathogenesis of epilepsy. A recent study by Xijin Liu and co-workers from Huazhong University of Science and Technology in China observed overexpression of Notch1 in the brain tissue of temporal lobe epilepsy rats. After Notch1 regulation, it was relatively effective in reducing seizure frequency and reducing brain discharges, thereby resulting in the ease of seizures to a certain extent. Increased presence of Notch 1 and hairy and enhancer of split-1 was also observed in intractable temporal lobe epilepsy patients. Therefore, Notch signaling may play a role in the pathogenesis of epilepsy in temporal lobe epilepsy and its suppression may provide a new treatment to promote remission in epilepsy. These findings were published in the Neural Regeneration Research (Vol. 9, No. 5, 2014).


'/>"/>

Contact: Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research
Source:Eurekalert  

Page: 1

Related medicine news :

1. Overexpression of proteins 14-3-3 related to chemotherapy resistance
2. MRI can screen patients for Alzheimers disease or frontotemporal lobar degeneration
3. Improved detection of frontotemporal degeneration may aid clinical trial efforts
4. Depression common among children with temporal lobe epilepsy
5. Epilepsy Leads to More Brain Abnormalities Over Time
6. Brain surgery for epilepsy underutilized
7. Response to First Treatment May Predict Epilepsys Course
8. Pediatric epilepsy impacts sleep for the child and parents
9. Parents Often Lose Sleep Over Childs Epilepsy, Study Finds
10. Epilepsy drugs increase risk of fractures and falls
11. Study finds new gene mutations that lead to enlarged brain size, cancer, autism, epilepsy
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Overexpression of Notch1 in temporal lobe epilepsy
(Date:3/28/2017)... ... 2017 , ... Via Oncology, the leading provider of oncology ... public-facing tool for analyzing the costs of various drug regimens in cancer care. ... patients, providers, insurers and pharmaceutical companies about the estimated costs of treatment options. ...
(Date:3/28/2017)... (PRWEB) , ... March 28, 2017 , ... ... announces today that the University of Pittsburgh Medical Center (UPMC) will acquire QuikClot® ... Western Pennsylvania. , The program, developed in association with efforts by the American ...
(Date:3/28/2017)... ... ... Usually, the impending arrival of warmer weather means the gleeful banishment of ... chin, this means more anxiety than elation. The cosmetic dermatology experts at Cosmetic Laser ... chin is undesirable,” Dr. Goldman said, “but it seems doubly so when the fat ...
(Date:3/28/2017)... ... March 28, 2017 , ... Calibration, ... to ensuring high-quality results and maintaining GMP and USP compliance. In a new ... accordance with GMP requirements " these requirements are explained. The challenge is ...
(Date:3/28/2017)... ... 2017 , ... Qualidigm , the mission-driven national healthcare ... new, more expansive office space in order to accommodate its growing number of ... building in Wethersfield, Conn. located at 936 Silas Deane Highway and immediately began ...
Breaking Medicine News(10 mins):
(Date:3/28/2017)... , March 28, 2017  Market leading ... announced a partnership with premium news content provider ... companies to extract key insights from Dow Jones ... technology. The Linguamatics I2E platform is ... global pharmaceutical companies. The Linguamatics-Dow Jones partnership helps ...
(Date:3/28/2017)... , March 28, 2017  CASI Pharmaceuticals, ... innovative therapeutics addressing cancer and other unmet medical ... American Association for Cancer Research annual meeting.  The ... is entitled "Evaluation of ENMD-2076 in Combination ... the second poster to be presented on April ...
(Date:3/28/2017)... , March 28, 2017 Elysium ... with Cambridge academic ...   The Milner Therapeutics Institute today announces Elysium ... Health has committed significant investment for collaborative projects with academic ... four years. This is the first major research investment outside ...
Breaking Medicine Technology: