Navigation Links
Overactive Blood Platelets May Play Role in Lupus
Date:9/1/2010

By Melissa Lee Phillips
HealthDay Reporter

WEDNESDAY, Sept. 1 (HealthDay News) -- Overactive blood platelets could trigger inflammation in those with lupus, but the anti-clotting drug Plavix might ease the painful symptoms of this autoimmune disease, a new study suggests.

Platelets, which are the colorless, disc-shaped blood cells that are key to clotting, are suspected to be involved in lupus, explained senior study author Dr. Patrick Blanco, of the University of Bordeaux in France, but "their precise role was poorly understood until now."

Systemic lupus erythematosus (SLE) is a chronic disease thought to develop when the body's own antibodies start attacking organs. Sufferers experience recurring pain and inflammation in many parts of their body. Some common symptoms include joint pain or swelling, muscle pain, fever with no known cause, and red rashes, often on the face, according to the U.S. National Library of Medicine.

The exact cause of lupus is unknown, although research suggests that both environmental and genetic factors contribute to the disease.

Presently, there is no cure for the disease, which can be fatal. Current treatments include steroids and chemotherapy-like drugs, but they have assorted toxic effects, the study authors noted.

Blanco and his colleagues theorized that blood platelets might be involved in lupus because of their known role in the inflammatory process. To test this theory, they examined the blood of 37 lupus patients and compared their platelets to those from individuals without the disease.

They found that platelets in people with lupus were abnormally "activated" -- they expressed too much of a protein that's involved in blood clotting. These activated platelets, in turn, triggered production of proteins called interferons, which are known to promote inflammation.

The authors found that destroying blood platelets in mice prone to lupus relieved symptoms
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Overactive Thyroid Linked to Stroke in Young Adults
2. McMaster study contradicts reports of problems with blood-thinner
3. Even modest weight gain can harm blood vessels, Mayo researchers find
4. Novel role: EZH2 boosts creation of ovarian cancer blood vessels
5. Scientists map epigenetic changes during blood cell differentiation
6. Selected cells from blood or bone marrow may provide a route to healing blood vessels
7. Just a Little Belly Fat Can Damage Blood Vessels
8. Caltech biologists discover microRNAs that control function of blood stem cells
9. MicroRNA molecule increases number of blood stem cells, may help improve cancer treatment
10. Experts Support FDA Panels Backing of New Blood Thinner
11. Implantable Sensor Measures Blood Sugar Levels
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Overactive Blood Platelets May Play Role in Lupus
(Date:12/20/2014)... LunaDress has recently announced its 2015 collection of ... on all of its special occasion dresses & wedding apparel. ... wedding gown. If you have no idea of what to ... different wedding dress styles and our dress experts are here ... current special offer, up to 80% off," the CEO of ...
(Date:12/20/2014)... The print component of Healthy Aging is distributed ... 160,000 copies and an estimated readership of 420,000. The ... media strategy and across a network of top news ... of the campaign, click here . , The ... of CTV’s The Social. Lainey Lui, Melissa Grelo, ...
(Date:12/20/2014)... Recently, VogueQueen.com, a leading wedding dress ... Sale Online for 2015. Great discounts are now ... old consumers can get a discount, up to 80% ... website before January 30, 2015. , VogueQueen.com has recently ... a prom dress promotion. Many customers worldwide like VogueQueen’s ...
(Date:12/20/2014)... December 20, 2014 Angeldress.co.uk, the distinguished ... great for worldwide dress fans. The company has recently ... and information. For the holiday season, Angeldress Blog ... special wedding apparel. , Angeldress.co.uk prides itself in offering ... level of service. All the company’s outfits are very ...
(Date:12/20/2014)... 20, 2014 Atore, Inc, (San Francisco, ... launched first birthday focused portal on December 17th, 2014. ... launched in both US and Japan. , MERRY BIRTHDAY ... http://merrybirthday.net/message/ , MERRY BIRTHDAY MESSAGE is part ... the world. , Features, Choose from thousands of stock ...
Breaking Medicine News(10 mins):Health News:2015 Collection of Wedding Dresses from LunaDress Online on Sale Now 2Health News:The ladies of The Social urge Canadian women to put themselves first over the holiday season and into the new year in Mediaplanet’s “Women’s Health” campaign 2Health News:VogueQueen Big Sale Online For The Coming 2015 2Health News:Trendy Professional Wedding Apparel Recommended by Angeldress Blog 2Health News:Atore, Inc. Releasing the First Birthday Portal 2
... ... IBM ) today announced that its lending arm, IBM Global ... healthcare records (EHR) providers, highlighting the growing need for private financing ... face to adopt health IT solutions. , (Logo: http://www.newscom.com/cgi-bin/prnh/20090416/IBMLOGO ...
... , RANCHO SANTA FE, Calif., Dec. 22 ... checking them twice, Helen Woodward Animal Center (HWAC) began a quest ... Puerto Rico,s Canita Animal Sanctuary the HWAC team from Rancho Santa ... the largest Humane Society facility on the island only three of ...
... , ... 22 /PRNewswire-Asia/ -- Avery Dennison Specialty Tape has,developed a proprietary ... Its newest generation of ultra-thin hydrocolloid,adhesives delivers real consumer benefits ... skin softening beneath the dressing, and,gentle removal. , ...
... ... effective in the alleviation of symptoms associated with many chronic conditions such as allergies, ... 300 practices throughout the country are using this holistic therapy including over 50 branded ... ...
... Make your New ... for 2010. So says Australian weight loss and dieting researcher, Mr Trevor Johnson. With an epidemic ... new year,s weight loss resolutions fail within the first week. The primary cause of the failure ... (PRWEB) ...
... study published in the January issue of Radiology , ... MRI declined to undergo the procedure. "Given that ... early breast cancer, we were surprised that barely half of ... even when offered at no cost," said Wendie A. Berg, ...
Cached Medicine News:Health News:IBM Financing Agreements With Electronic Healthcare Record Providers Shatter Barriers To Health IT Adoption 2Health News:IBM Financing Agreements With Electronic Healthcare Record Providers Shatter Barriers To Health IT Adoption 3Health News:IBM Financing Agreements With Electronic Healthcare Record Providers Shatter Barriers To Health IT Adoption 4Health News:IBM Financing Agreements With Electronic Healthcare Record Providers Shatter Barriers To Health IT Adoption 5Health News:While Some Were Counting Sugar Plums...Others Were Changing the Future 2Health News:Avery Dennison Innovates in Consumer Wound Care 2Health News:Avery Dennison Innovates in Consumer Wound Care 3Health News:BioVeda Health and Wellness Center of Nampa, ID Announces its Grand Opening 2Health News:BioVeda Health and Wellness Center of Nampa, ID Announces its Grand Opening 3Health News:BioVeda Health and Wellness Center of Nampa, ID Announces its Grand Opening 4Health News:BioVeda Health and Wellness Center of Nampa, ID Announces its Grand Opening 5Health News:Making New Year's Resolution Today is Key to 2010 Weight Loss & Dieting Success 2Health News:Elevated-risk women refuse MRI breast cancer screening 2
(Date:12/19/2014)... CARDIFF-BY-THE-SEA, Calif. , Dec. 19, 2014 ... ;  Sorrento), an oncology company developing new treatments ... a privately-held immuno-oncology company developing proprietary Neukoplast ® ... therapy, announced today that the companies have entered ... generation CAR-TNK™ (pronounced as "Car-Tank") immunotherapies for the ...
(Date:12/19/2014)... Dec. 18, 2014  Decision Resources Group finds that ... States will increase to a value of ... driven by expansion in the large direct energy device ... be increasingly adopted due to the advantages they offer ... key findings from Decision Resources Group,s coverage of the ...
(Date:12/19/2014)... CITY, Kan. , Dec. 18, 2014 /PRNewswire/ ... PETX ), a biopharmaceutical company focused on the ... companion animals, today announced positive results from its ... innovative drug for treating pain in dogs with ... improvements in pain assessment scores that were statistically ...
Breaking Medicine Technology:Sorrento and Conkwest Announce Exclusive Global Collaboration 2Sorrento and Conkwest Announce Exclusive Global Collaboration 3Sorrento and Conkwest Announce Exclusive Global Collaboration 4Sorrento and Conkwest Announce Exclusive Global Collaboration 5U.S. Laparoscopic Device Market Will Reach Over $4.3 Billion by 2023 2U.S. Laparoscopic Device Market Will Reach Over $4.3 Billion by 2023 3Aratana Therapeutics Announces Positive Top-Line Results from AT-001 Pivotal Field Study in Client-Owned Dogs with Osteoarthritis 2Aratana Therapeutics Announces Positive Top-Line Results from AT-001 Pivotal Field Study in Client-Owned Dogs with Osteoarthritis 3Aratana Therapeutics Announces Positive Top-Line Results from AT-001 Pivotal Field Study in Client-Owned Dogs with Osteoarthritis 4Aratana Therapeutics Announces Positive Top-Line Results from AT-001 Pivotal Field Study in Client-Owned Dogs with Osteoarthritis 5
... - Over 1,500 U.S. patients enrolled in study examining potential ... ,GI-friendly, treatment for mild to moderate pain - ... expected in second half of 2008 -, PALO ALTO, ... company, today announced that it is,closing enrollment in its two ...
... ... Hypertension Study, PRINCETON, N.J., Feb. 11 ... development of novel,small molecule therapeutics, today announced the nomination of PS031291 ... a potent and highly selective antagonist at the,chemokine receptor CCR1, which ...
Cached Medicine Technology:Horizon Therapeutics Completes Enrollment in Phase 3 Trials for Lead Product Candidate HZT-501 2Horizon Therapeutics Completes Enrollment in Phase 3 Trials for Lead Product Candidate HZT-501 3Pharmacopeia Nominates Novel Chemokine Receptor Antagonist for Development 2Pharmacopeia Nominates Novel Chemokine Receptor Antagonist for Development 3Pharmacopeia Nominates Novel Chemokine Receptor Antagonist for Development 4
... DBM Matrix PLF is ... material designed specifically for ... trough-like design allows for ... bone. Demineralized bone fibers ...
Demineralized bone matrix dispensed in a syringe. DBM will be free of foreign matter. Demineralized bone matrix particle size 125 to 850 . Glycerol 70-88% by weight. Calcium content less than 8%....
... Olympus' new generation Endoalpha is a centralized ... surgeon and the nurse by giving them ... Endoalpha provides protection against obsolescence, as future ... than the purchase of an entirely new ...
... systems two-piece design provides maximum positioning flexibility while ... for safe storage and easy transport. The system ... of floor space, but at the same time ... sterile field. Both the camera and display of ...
Medicine Products: