Navigation Links
Over half of Alzheimer's cases may be preventable, say researchers

Over half of all Alzheimer's disease cases could potentially be prevented through lifestyle changes and treatment or prevention of chronic medical conditions, according to a study led by Deborah Barnes, PhD, a mental health researcher at the San Francisco VA Medical Center.

Analyzing data from studies around the world involving hundreds of thousands of participants, Barnes concluded that worldwide, the biggest modifiable risk factors for Alzheimer's disease are, in descending order of magnitude, low education, smoking, physical inactivity, depression, mid-life hypertension, diabetes and mid-life obesity.

In the United States, Barnes found that the biggest modifiable risk factors are physical inactivity, depression, smoking, mid-life hypertension, mid-life obesity, low education and diabetes.

Together, these risk factors are associated with up to 51 percent of Alzheimer's cases worldwide (17.2 million cases) and up to 54 percent of Alzheimer's cases in the United States (2.9 million cases), according to Barnes.

"What's exciting is that this suggests that some very simple lifestyle changes, such as increasing physical activity and quitting smoking, could have a tremendous impact on preventing Alzheimer's and other dementias in the United States and worldwide," said Barnes, who is also an associate professor of psychiatry at the University of California, San Francisco.

The study results were presented at the 2011 meeting of the Alzheimer's Association International Conference on Alzheimer's Disease in Paris, France, and published online on July 19, 2011 in Lancet Neurology.

Barnes cautioned that her conclusions are based on the assumption that there is a causal association between each risk factor and Alzheimer's disease. "We are assuming that when you change the risk factor, then you change the risk," Barnes said. "What we need to do now is figure out whether that assumption is correct."

Senior investigator Kristine Yaffe, MD, chief of geriatric psychiatry at SFVAMC, noted that the number of people with Alzheimer's disease is expected to triple over the next 40 years. "It would be extremely significant if we could find out how to prevent even some of those cases," said Yaffe, who is also a professor of psychiatry, neurology and epidemiology at UCSF.


Contact: Steve Tokar
University of California - San Francisco

Related medicine news :

1. In San Diego, Hispanics Now Dominate HIV/TB Cases
2. Prednisolone not benficial in most cases of community-acquired pneumonia
3. Avoiding Dairy Due to Lactose Intolerance is Unnecessary in Most Cases and May Pose Diet and Health Risks, Concludes National Institutes of Health Consensus Development Conference Panel
4. National Patient Advocate Foundation Delivers Constituent Cases to White House Health Summit Participants to Urge Elimination of Pre-Existing Conditions, Annual/Lifetime Limits and Capping Out-of-Pocket Expenses
5. CareTech Solutions Showcases Web Portal for Hospital Boards and Administrators at HIMSS10
6. Red Hot Artist Renea Menzies Has Flower Power; Houston, Texas Artist Renea Menzies Showcases Her Work in NY
7. Orion Health Showcases Industry Leading EHR Software at WoHIT
8. Hair Alcohol Test Kit to Help in Third of Care Cases
9. Women bear caregiving responsibility in cases of dependency in Spain
10. Rapid development of drug-resistant 2009 H1N1 influenza reported in 2 cases
11. Officials See Uptick in H1N1 Swine Flu Cases
Post Your Comments:
(Date:11/27/2015)... ... November 27, 2015 , ... ProSidebar: Fashion ... Cut Pro X. With ProSidebar: Fasion, video editors can easily add an informative ... a minimalist title opener. Utilize presets featuring self-animating drop zones, lines, bars, and ...
(Date:11/27/2015)... ... November 27, 2015 , ... Consistent with the ... 2016 Building Better Radiology Marketing Programs meeting will showcase some of ... 6, 2016, at Caesars Palace in Las Vegas with a pre-conference session on ...
(Date:11/27/2015)... ... ... A simply groundbreaking television series, "Voices in America", which is hosted by Hollywood ... issues that are presently affecting Americans. Dedicated to providing the world with a wide ... subjects consumers focus on, one episode at a time. , In the latest ...
(Date:11/27/2015)... ... November 27, 2015 , ... Keeping ... platform for mental health and wellness consultation, has collaborated with a leading web-based ... the knowledge gap experienced by parents and bring advice from parenting experts within ...
(Date:11/27/2015)... ... 2015 , ... The men and women on this list ... the country. They have overseen financial turnarounds, shown commitment to their community through ... as a whole through their advocacy and professional efforts. , Becker's Hospital Review ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... , November 26, 2015 ... the addition of the  "2016 Future ... European Therapeutic Drug Monitoring (TDM) Market: ... Intelligence, Emerging Opportunities"  report to their ... has announced the addition of the  ...
(Date:11/26/2015)... , November 26, 2015 ... the "Self Administration of High Viscosity Drugs" ... ) has announced the addition of the ... report to their offering. --> Research ... addition of the "Self Administration of High ...
(Date:11/26/2015)... DUBLIN , November 26, 2015 /PRNewswire/ ... the addition of the "Radioimmunoassay Market ... User (Hospital, Pharmaceutical Industry, Academics, Clinical Diagnostic ... - Global Forecast to 2020" report ... ) has announced the addition of the ...
Breaking Medicine Technology: