Navigation Links
Ovarian function and fertility preserved in women with severe systemic lupus erythematosus
Date:6/12/2008

Paris, France, Thursday 12 June 2008: Ovarian function can be preserved and disease activity controlled in women with severe systemic lupus erythematosus (SLE) when treated with a 6-month course of cyclophosphamide (CYC), a chemotherapy drug, followed by the immunosuppressant mycophenolate mofetil (MMF), according to a new study presented today at EULAR 2008, the Annual Congress of the European League Against Rheumatism in Paris, France.

SLE, a complex and unpredictable autoimmune disease, is characterised by chronic inflammation and damage of body tissues, including the heart, lungs, kidneys, joints, and/or nervous system. It is most common in women and, although long-term survival has dramatically improved over time with better diagnosis and treatment options, one of the challenges in managing the disease is to minimise the side-effects of treatments such as the disruption of ovarian function and risks to fertility. Pulsed intravenous CYC, a chemotherapeutic agent, is a standard therapy for SLE but may also be associated with ovarian failure in addition to other adverse effects.

Dr Katerina Laskari, the presenting author of the study, led by Professor Athanasios G Tzioufas in the Department of Pathophysiology of the National and Kapodistrian University of Athens, said: "Although the prognosis for people with SLE has considerably improved over the years, a patient's quality of life can all too often be seriously impaired by the toxicity of many commonly-used treatments. Preserving ovarian function is a very important consideration in treating women with SLE of child-bearing age, who are already burdened by the difficult nature and impact of the disease itself."

In this retrospective evaluation of 61 postmenopausal women with SLE treated for lupus nephritis (n=58), autoimmune hemolytic anemia (n=1) and central nervous system involvement (n=2), 39 patients received prolonged treatment with 1g/m2 intravenous (IV) CYC pulses (group A)
'/>"/>

Contact: Rory Berrie / Camilla Dormer
eularpressoffice@uk.cohnwolfe.com
44-077-892-70392
European League Against Rheumatism
Source:Eurekalert

Page: 1 2

Related medicine news :

1. A Knock-Out Match: Kelly Ripa and Molly Sims Team Up to Fight Ovarian Cancer
2. Coveting the Latest Clutch? Bid on a Bag and Help Fight Ovarian Cancer
3. Seattle-Based Marsha Rivkin Center for Ovarian Cancer Research Appoints Nancy Sclater, Executive Director
4. Stored Ovarian Tissue Needs Testing Before Re-Implantation
5. Cancer could return unless stored ovarian tissue undergoes adequate testing before re-implantation
6. Drug compound leads to death of ovarian cancer cells resistant to chemotherapy
7. FASgen Diagnostic Tests Identify Ovarian Cancer Progression and Apoptosis
8. Specialized Care for Ovarian Cancer Improves Outcomes
9. Recurrent low-grade carcinoma of the ovary less responsive to chemo than more common ovarian cancers
10. Advanced-stage ovarian cancer patients with BRCA live longer, may respond better to treatment
11. Gleevec May Disrupt Ovarian Function
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/3/2015)... ... 2015 , ... Approved provider of Florida Physical Therapy ... for the month of August. , Physical therapy professionals in Florida can register ... Physical Therapy Flex package. Flex packages allow therapists to combine best selling text, ...
(Date:8/3/2015)... Indiana (PRWEB) , ... August 03, 2015 , ... ... throughout Livingston and Putnam counties. As a family owned and operated business, ... septic matters. They are a leader in septic installations because of their ...
(Date:8/3/2015)... ... August 03, 2015 , ... Since 1978, the number of black males ... new publication released today by the AAMC (Association of American Medical Colleges). , ... past three decades, the number of black male applicants to medical school dropped to ...
(Date:8/3/2015)... ... August 03, 2015 , ... According to an opinion piece published July 28 by ... to one pound of weight loss may not be accurate. While this system may work ... pound of fat varies – based both on the individual and at what point that ...
(Date:8/3/2015)... , ... August 03, 2015 , ... ... in 2015 MarketingProfs Bright Bulb B2B Awards. , The MarketingProfs Bright Bulb B2B ... B2B brands. BESLER Consulting's campaign for the launch of their Readmissions Analytics product ...
Breaking Medicine News(10 mins):Health News:Elite Online CE Provider Announces Schedule of Live Courses For Florida Physical Therapy Continuing Education 2Health News:Elite Online CE Provider Announces Schedule of Live Courses For Florida Physical Therapy Continuing Education 3Health News:Zeiter’s Septics Performs Affordable Septic Installations Throughout Livingston & Putnam Counties Effective Immediately 2Health News:Zeiter’s Septics Performs Affordable Septic Installations Throughout Livingston & Putnam Counties Effective Immediately 3Health News:New Publication Focuses on the Decline of Black Males in Medicine 2Health News:New Publication Focuses on the Decline of Black Males in Medicine 3Health News:New Publication Focuses on the Decline of Black Males in Medicine 4Health News:Article Dispelling Weight Loss Myth Correctly Emphasizes the Complicated and Difficult Nature of Weight Loss, Says Dr. Michael Feiz 2
... the Australian Institute of Health and Welfare (AIHW) has found ... heart attacks and cardiovascular disease at rates that are higher ... researchers have also reported in their study that people in ... hospital for the disease. The researchers have explained that their ...
... Roy Thayer’s underwent an emergency life saving operation by writing a ... was reported that Roy, 77, was warned that the long wait ... knew that there was no way he could afford to pay ... the operation at a private hospital, knowing fully well that by ...
... well into childhood long after children are weaned according ... revealed that breast-fed children cope better with stressful situations ... ,Dr Scott Montgomery, an epidemiologist at the Karolinska ... there is less of an association between parental divorce ...
... forum on HIV/AIDS for the UN will be among ... from Aug 13. // ,"Canada is eager ... disparities in access to HIV treatment throughout the world," ... the McGill University AIDS Center. ,The biennial ...
... cancer-fighting properties of tulsi, which is grown in many Indian ... 10 students at the University of Rajasthan.// ,"We arrived ... said Ashok Sharma, who heads the research project. ... IANS. The rats were first divided into two groups and ...
... sudden, worsening chest pain or a certain type of ... invasive treatment// rather than being treated conservatively, a new ... evidence suggests that an early invasive strategy is superior ... of the Centre for Research in Vascular Biology at ...
Cached Medicine News:Health News:Wily Old Man Undergoes A life Saving Operation With A Worthless Cheque 2Health News:Childhood Anxiety Reduced with Breast-feeding 2Health News:Indian to Conduct Workshop at Global AIDS Meet 2Health News:Emergency Heart Patients Do Better With Invasive Approach 2Health News:Emergency Heart Patients Do Better With Invasive Approach 3Health News:Emergency Heart Patients Do Better With Invasive Approach 4
(Date:8/3/2015)... 3, 2015 Discovery Laboratories, Inc. (Nasdaq: ... on developing aerosolized KL4 surfactant therapies for respiratory ... at 8:30 a.m. Eastern Time on Tuesday August 11, ... 2015 second quarter financial results along with providing ... press release announcing the second quarter 2015 financial ...
(Date:8/3/2015)... Aug. 3, 2015 Diplomat Pharmacy, Inc. (NYSE: ... results for the quarter ended June 30, 2015. All comparisons, ... 2014. Second Quarter 2015 Highlights include: ... or $266 million , Total prescriptions dispensed of 234,000, ... versus 5.5% , Adjusted EBITDA of $22.7 million, an ...
(Date:8/3/2015)... CHESTNUT RIDGE, N.Y. , Aug. 3, 2015 /PRNewswire/ ... will host a conference call on Friday, August 7, ... of operations for the second quarter ended June 30, ... financial information available to the public in its filings ... certain other information available on its website by following ...
Breaking Medicine Technology:Discovery Labs to Hold Conference Call on Tuesday August 11, 2015 to Discuss Second Quarter 2015 Financial Results and Other Business Updates 2Diplomat Announces 2nd Quarter 2015 Financial Results 2Diplomat Announces 2nd Quarter 2015 Financial Results 3Diplomat Announces 2nd Quarter 2015 Financial Results 4Diplomat Announces 2nd Quarter 2015 Financial Results 5Diplomat Announces 2nd Quarter 2015 Financial Results 6Diplomat Announces 2nd Quarter 2015 Financial Results 7Diplomat Announces 2nd Quarter 2015 Financial Results 8Diplomat Announces 2nd Quarter 2015 Financial Results 9Diplomat Announces 2nd Quarter 2015 Financial Results 10Diplomat Announces 2nd Quarter 2015 Financial Results 11Diplomat Announces 2nd Quarter 2015 Financial Results 12Diplomat Announces 2nd Quarter 2015 Financial Results 13Diplomat Announces 2nd Quarter 2015 Financial Results 14Diplomat Announces 2nd Quarter 2015 Financial Results 15Diplomat Announces 2nd Quarter 2015 Financial Results 16Diplomat Announces 2nd Quarter 2015 Financial Results 17Diplomat Announces 2nd Quarter 2015 Financial Results 18
... Jan. 18, 2011 BNY Mellon and The SSI Group, ... of the alliance between the two companies, SSI,s health care ... bill payment capabilities.   Under this agreement, health ... button to the screens they use in interacting with SSI,s ...
... AUSTIN, Texas, Jan. 18, 2011 Hanger Orthopedic Group, Inc. (NYSE: ... its results of operations for the quarter ended December 31, 2010, ... issue a press release announcing the results for the quarter ended ... February 9, 2011 after the close of the market. A conference ...
Cached Medicine Technology:The SSI Group to Provide Health Care Providers with BNY Mellon's Electronic Payment Solutions 2The SSI Group to Provide Health Care Providers with BNY Mellon's Electronic Payment Solutions 3Hanger Orthopedic Group, Inc. Announces Fourth Quarter 2010 Earnings Release Conference Call 2
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: