Navigation Links
Ovarian function and fertility preserved in women with severe systemic lupus erythematosus
Date:6/12/2008

Paris, France, Thursday 12 June 2008: Ovarian function can be preserved and disease activity controlled in women with severe systemic lupus erythematosus (SLE) when treated with a 6-month course of cyclophosphamide (CYC), a chemotherapy drug, followed by the immunosuppressant mycophenolate mofetil (MMF), according to a new study presented today at EULAR 2008, the Annual Congress of the European League Against Rheumatism in Paris, France.

SLE, a complex and unpredictable autoimmune disease, is characterised by chronic inflammation and damage of body tissues, including the heart, lungs, kidneys, joints, and/or nervous system. It is most common in women and, although long-term survival has dramatically improved over time with better diagnosis and treatment options, one of the challenges in managing the disease is to minimise the side-effects of treatments such as the disruption of ovarian function and risks to fertility. Pulsed intravenous CYC, a chemotherapeutic agent, is a standard therapy for SLE but may also be associated with ovarian failure in addition to other adverse effects.

Dr Katerina Laskari, the presenting author of the study, led by Professor Athanasios G Tzioufas in the Department of Pathophysiology of the National and Kapodistrian University of Athens, said: "Although the prognosis for people with SLE has considerably improved over the years, a patient's quality of life can all too often be seriously impaired by the toxicity of many commonly-used treatments. Preserving ovarian function is a very important consideration in treating women with SLE of child-bearing age, who are already burdened by the difficult nature and impact of the disease itself."

In this retrospective evaluation of 61 postmenopausal women with SLE treated for lupus nephritis (n=58), autoimmune hemolytic anemia (n=1) and central nervous system involvement (n=2), 39 patients received prolonged treatment with 1g/m2 intravenous (IV) CYC pulses (group A)
'/>"/>

Contact: Rory Berrie / Camilla Dormer
eularpressoffice@uk.cohnwolfe.com
44-077-892-70392
European League Against Rheumatism
Source:Eurekalert

Page: 1 2

Related medicine news :

1. A Knock-Out Match: Kelly Ripa and Molly Sims Team Up to Fight Ovarian Cancer
2. Coveting the Latest Clutch? Bid on a Bag and Help Fight Ovarian Cancer
3. Seattle-Based Marsha Rivkin Center for Ovarian Cancer Research Appoints Nancy Sclater, Executive Director
4. Stored Ovarian Tissue Needs Testing Before Re-Implantation
5. Cancer could return unless stored ovarian tissue undergoes adequate testing before re-implantation
6. Drug compound leads to death of ovarian cancer cells resistant to chemotherapy
7. FASgen Diagnostic Tests Identify Ovarian Cancer Progression and Apoptosis
8. Specialized Care for Ovarian Cancer Improves Outcomes
9. Recurrent low-grade carcinoma of the ovary less responsive to chemo than more common ovarian cancers
10. Advanced-stage ovarian cancer patients with BRCA live longer, may respond better to treatment
11. Gleevec May Disrupt Ovarian Function
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2015)... 24, 2015 ... - The students were selected ... the fourth annual A Day of ... Geneva National in Lake Geneva. , ... High School,         Jonathan Alfonso,         Bridget Keefe, ...
(Date:5/23/2015)... (PRWEB) May 23, 2015 With the ... businesses, are finding it increasingly difficult to provide their ... fail to provide adequate insurance for employees stand to ... been such an integral part of a business’s success ... healthcare for businesses, Online USA Doctors has created a ...
(Date:5/23/2015)... Javon Bea Mercy Health System CEO ... Center, 557 N. Washington St., Janesville, will host an ... pm. , The 8-week clinic is lead by Brent ... who will offer training that encompasses a warm-up, training ... show selection and weekly training plans. , The program ...
(Date:5/22/2015)... The American College of Traditional Chinese ... They will hold a webinar on the updates of ... on Classical Chinese Medicine. , Webinar – First Professional ... the Dean of Clinical Education, will lead this webinar ... Doctorate program. ACTCM is currently developing this degree program ...
(Date:5/22/2015)... May 22, 2015 Omar Ahmad Barrada, ... to participate in the 2015 Congress of Future Medical ... as a gathering of “America’s highest achieving high school ... of healthcare, set new goals and learn better study ... live surgery, during which we can ask the surgeons ...
Breaking Medicine News(10 mins):Health News:Mercy Foundation Honors 16 Students for Making a Difference - Mercy Health System Javon Bea 2Health News:Online USA Doctors Now Offers Cost-Saving Alternative Healthcare for Businesses 2Health News:Online USA Doctors Now Offers Cost-Saving Alternative Healthcare for Businesses 3Health News:ACTCM Announces Upcoming June Events 2Health News:Milton Hershey School Student Chosen for Congress of Future Medical Leaders 2
... Amanda Gardner HealthDay Reporter , TUESDAY, Nov. 16 ... defective one, scientists were able to partially restore the heart,s ... "This is the first time gene therapy has been ... heart failure," study lead author Dr. Donna Mancini, professor of ...
... prescription filled can undermine medical treatment, result in increased ... the patient. An editorial in the Nov. 16 issue ... the problem and issues a call to action. ... Nonadherence," Michael D. Murray, PharmD, MPH, a Regenstrief Institute, ...
... HealthDay Reporter , MONDAY, Nov. 15 (HealthDay News) ... those involved: Sometimes surgical instruments and sponges are left inside ... Children suffering from such mishaps were not more likely ... are more than twice as long and cost more than ...
... 1 and 1-1/2, children who get most of their sleep at ... variety of skill areas than children who don,t sleep as much ... conducted by researchers at the University of Montreal and the University ... the journal Child Development . The study, of 60 ...
... cancer appear more likely to experience hearing loss and to ... not receive such treatment, according to a report in the ... , one of the JAMA/Archives journals. Head and neck ... according to background information in the article. Treatment methods include ...
... MONDAY, Nov. 15 (HealthDay News) -- In Australia, where universal ... much more prevalent among poor citizens than it is among ... researchers say that differences in risk do exist between the ... heart disease is typically thought of as more prevalent in ...
Cached Medicine News:Health News:Gene Therapy Shows Potential Against Heart Failure 2Health News:Not following doctor's orders: Prescription abandonment 2Health News:Sponges, Surgical Tools Sometimes Left in Kids After Operation 2Health News:Sponges, Surgical Tools Sometimes Left in Kids After Operation 3Health News:Nighttime sleep found beneficial to infants' skills 2Health News:Hearing loss common following radiation therapy for head and neck cancer 2Health News:Universal Health Care May Lessen Income's Impact on Heart Disease 2
(Date:5/22/2015)... , May 22, 2015  The Mesothelioma Victims ... victims of mesothelioma get the best possible compensation, ... individuals with this rare cancer caused by exposure ... up-to-date information related to treatment options such as ... call the Mesothelioma Victims Center anytime at 866-714-6466. ...
(Date:5/22/2015)... 20, 2015 Research and Markets( http://www.researchandmarkets.com/research/28m7nx/guide_to_prepare ... "Guide to Prepare Application Dossiers for Oversea Medical ... " report to their offering. ... segment market of the most growth potentiality, which ... manufacturers and producers to penetrate such market. It ...
(Date:5/22/2015)... , May 22, 2015 Research and Markets ... addition of the "Latest Regulations on Pharmaceutical ... to their offering. This is first ... a guidance on international multi-center clinical trials of ... has begun to be implemented on March 1, ...
Breaking Medicine Technology:Mesothelioma Victims Center Calls Attention to a Recent Medical Article About a New Drug That Could Slow the Progression of Mesothelioma and Allow People to Live Longer 2Mesothelioma Victims Center Calls Attention to a Recent Medical Article About a New Drug That Could Slow the Progression of Mesothelioma and Allow People to Live Longer 3Mesothelioma Victims Center Calls Attention to a Recent Medical Article About a New Drug That Could Slow the Progression of Mesothelioma and Allow People to Live Longer 4Mesothelioma Victims Center Calls Attention to a Recent Medical Article About a New Drug That Could Slow the Progression of Mesothelioma and Allow People to Live Longer 5China Guide to Prepare Application Dossiers for Oversea Medical Device Registration and Recordation 2China Guide to Prepare Application Dossiers for Oversea Medical Device Registration and Recordation 32015 Regulations on Pharmaceutical International Multi-Center Clinical Trials in China 2
... DIEGO, April 14, 2011 LifeVantage Corporation (OTCBB: ... preliminary net revenue for its third fiscal quarter of 2011 ... $2.6 million or 35% over net revenue of $7.4 million ... is also an approximate $7.3 million or 270% increase in ...
... Attorney General Roy Cooper warned the House Special Select ... immunity to pharmaceutical companies could cost North Carolina taxpayers ... dollars." Still, the GOP-controlled committee, led by ... could go to the House floor for a vote ...
Cached Medicine Technology:LifeVantage Announces Preliminary Third Quarter 2011 Revenue 2GOP's Big Pharma Protection to Cost NC Taxpayers "Hundreds of Millions" 2
... Catheter is indicated for balloon ... of a coronary artery or ... purpose of improving myocardial perfusion. ... also designed to provide distal ...
16mm from Mid-screw to Tips, blunt tips; overall length 110mm; Stainless Steel...
Angled 45 Degrees to Right, 9.5mm blade, gently curved .5x .25mm blunt tips; Lower blade is 0.5mm longer; 14mm from mid screw to tip; (Available in left and right; ) overall length 120mm; Stainless ...
Two prong stainless steel tips; with titanium handle/...
Medicine Products: