Navigation Links
Ovarian cancer study offers vital clues for new therapies
Date:4/21/2010

Scientists have taken a major step forward in the understanding of ovarian cancer, which could improve treatment for patients with the condition.

Researchers have found that patients with hereditary ovarian cancer whose tumours are caused by faulty genes are more likely to experience secondary tumours in their liver and spleen. This is despite the fact that their overall prognosis is better than other patients.

In non-hereditary cancer, ovarian tumours tend to remain within the lining of the abdomen and pelvis.

A University of Edinburgh study suggests that ovarian cancer patients whose tumours spread to the solid organs such as the liver and lungs should be tested for the faulty genes BRCA1 and BRCA2 to ensure they are given the most appropriate treatment.

Researchers say this would improve the detection of these faulty genes as current criteria for genetic testing may miss as many as two-thirds of ovarian cancer patients carrying faulty BRCA genes.

Patients with hereditary tumours, which account for 10 per cent of ovarian cancers, may also be suitable for trials of a new drug called olaparib, which has fewer side-effects than normal cancer treatments.

Improving the identification of BRCA mutations would help relatives of ovarian cancer patients, who may themselves be at increased risk of developing hereditary cancer.

The research is published in the Journal of Clinical Oncology.

Dr Charlie Gourley, who led the research at the University of Edinburgh, said: "We are beginning to understand the importance of tailoring cancer treatments according to the specifics of each patient's tumour. These findings demonstrate that tumours which arise because of defects in the BRCA1 or BRCA2 genes behave differently to other ovarian cancers. This information should also help us to identify the patients carrying these genetic mutations, give them the most effective treatment for their cancer an
'/>"/>

Contact: Anna Borthwick
anna.borthwick@ed.ac.uk
44-131-651-4400
University of Edinburgh
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Only women with Western Swedish breast cancer gene run higher risk of ovarian cancer
2. Pre-Diagnosis Diet Linked to Ovarian Cancer Survival
3. Study finds delay in referrals for older women with ovarian cancer
4. Foster Friess commits up to $50,000 to help TGen fight ovarian cancer
5. How to make the best decisions when at high risk for breast or ovarian cancer
6. Symptoms have little value for early detection of ovarian cancer
7. Symptoms Alone Dont Spot Ovarian Cancer Early
8. Ultrasound plus proteomic blood analyses may help physicians diagnose early-stage ovarian cancer
9. Abbott Receives European Regulatory Approval for New Ovarian Cancer Diagnostic Test
10. Research suggests link between infertility, low egg reserve, and breast/ovarian cancer gene (BRCA1)
11. Arrayit Diagnostics to Bring First Pre-Symptomatic Ovarian Cancer Blood Test to Multi-Billion Dollar Diagnostic Market in 2010
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/27/2015)... 27, 2015 FACE Skincare~Medical~Wellness, a ... announced a unique combination to take fifteen years ... Décolletage is a new treatment introduced that is ... specifically indicated to improve lines and wrinkles on ... person who suffers from the stubborn vertical lines ...
(Date:2/27/2015)... (PRWEB) February 27, 2015 The UC ... research expertise have made it a beacon of hope ... beyond, has been acknowledged by the national society committed ... the Huntington’s Disease Society of America — as a ... The acknowledgement recognizes the center’s service to over 300 ...
(Date:2/27/2015)... Healthpointe is now performing arthroscopy ... or diseases affecting the elbow , wrist ... throughout Southern California, and are dedicated in providing ... related to the upper extremities. , Dr. ... board-certified and fully trained in treating an array ...
(Date:2/27/2015)... 27, 2015 Wimbledon Health ... provides vascular, echocardiogram and NCV testing with state-of-the-art ... preferred diagnostic testing provider for young athletes at ... liberal arts university in Milledgeville, Georgia. , ... U collegiate division, include a non-invasive vascular ...
(Date:2/27/2015)... The Lymphoma Research Foundation (LRF) – ... innovative lymphoma research and serving the lymphoma community through ... patient services – is continuing to make its presence ... greater Miami area to host Swirl, A Wine Tasting ... Beach on Thursday, March 26, 2015. This year’s wine ...
Breaking Medicine News(10 mins):Health News:Face Skincare Announces New Combination Therapy 2Health News:UC Davis Huntington's Disease Center Receives Level 1 Designation 2Health News:UC Davis Huntington's Disease Center Receives Level 1 Designation 3Health News:Healthpointe is Now Performing Arthroscopic Surgery Techniques for Elbow, Hand and Wrist Injuries and Diseases, such as certain Ganglion Cysts 2Health News:Georgia College Ensures Student-Athletes Are Heart Smart Team Strong; Teams up with Wimbledon Health Partners to Offer Diagnostic Testing 2Health News:Georgia College Ensures Student-Athletes Are Heart Smart Team Strong; Teams up with Wimbledon Health Partners to Offer Diagnostic Testing 3Health News:Lymphoma Research Foundation Returns to Miami Beach For Exclusive Swirl Wine Tasting Event 2
... Michael McDowell has today insisted that he and his ... completely united within the Progressive Democrats Party and in ... of alleged reports that relationship between the two Cabinet ... the leader of the junior coalition partner. It was ...
... 200 people in the United States and the Far East ... lead to blindness. ,Investigators have warned contact lens ... warning has lead to the withdrawal of one type of ... of those affected. ,Researchers have also explained that ...
... University of Alabama biostatistician has compiled a report on that ... in this venture by 19 other scientists in the United ... more than 100 studies on the reasons for obesity besides ... be an answer ,* Inadequate sleep: Sleep deprivation ...
... educational facilities to enhance their knowledge base. // ... will be included in the first phase of the ... satellite for education launched in 2004. ,In ... and it will be subsequently introduced in private schools. ...
... a new set of dietary guidelines. Apart from the ... as U.S. Dietary Guidelines, the revised Food Guide Pyramid ... ,All the guidelines though are given by ... rules mentioned by all are increased intake of fruit ...
... their chances of breast cancer, a study says. ,Researchers ... Research on Cancer in France analysed 1,600 women. He found ... mutations who had undergone a chest X-ray were 54 percent ... never undergone the procedure. ,Women who were exposed ...
Cached Medicine News:Health News:Investigations Reveal That Infections Due To Contact lens Could Cause Blindness 2Health News:India's Northeast Students to Get Satellite-based Education Soon 2
(Date:2/27/2015)... YORK , Feb. 27, 2015 Securities ... the board of Salix Pharmaceuticals, Ltd. (NASDAQ: ... $158.00 per share. Concerned SLXP investors are encouraged to ... The investigation focuses upon the shareholder ... agreement, Salix shareholders would receive only $158.00 per share ...
(Date:2/27/2015)... HOUSTON, TX , Feb. 27, 2015 /PRNewswire/ - ESSA ... Bloom Burton & Co. Ltd. ("Bloom Burton") today announced ... "Lock-Up") 2,353,130 common shares of the Company ("Common Shares") ... the Lock-Up. Of the Common Shares released from the ... release from the Lock-Up while the remainder will be ...
(Date:2/27/2015)... MARLBOROUGH, Mass. , Feb. 27, 2015  Boston ... to participate in the Barclays 2015 Annual Healthcare Conference ... . Dan Brennan , executive vice ... , vice president, Investor Relations, will participate in a ... the host analyst at approximately 1:05 p.m. ET. Following ...
Breaking Medicine Technology:ESSA Pharma and Bloom Burton announce additional release of shares from voluntary lock-up agreement 2ESSA Pharma and Bloom Burton announce additional release of shares from voluntary lock-up agreement 3ESSA Pharma and Bloom Burton announce additional release of shares from voluntary lock-up agreement 4Boston Scientific to Participate in the Barclays 2015 Annual Healthcare Conference 2
... 2011 Misonix, Inc. (NASDAQ: MSON ... and markets innovative therapeutic ultrasonic products worldwide for ... surgery and other surgical and medical applications, announced ... Symposium on Advances in Skin and Wound Care ...
... Every year thousands of children are hospitalized — and ... (Logo: http://photos.prnewswire.com/prnh/20090824/FDALOGO) Teens share stolen prescription ... pills that look like candy. In this ... can prevent harm by locking your medicine up. ...
Cached Medicine Technology:Misonix Exhibits at 26th Annual Clinical Symposium on Advances in Skin and Wound Care 2Misonix Exhibits at 26th Annual Clinical Symposium on Advances in Skin and Wound Care 3
... fast, single-solution staining, Hema-Quik II ... slides into stain solution for ... to deionized water for five ... second time by dipping quickly ...
Used in stat or routine procedures utilizing the dip or rack method of staining blood smears or as a counter-stain in reticulocyte counting. Comes as a part of a kit (8 oz each), or in 16 oz, 32 oz a...
... Our Buffered Wright-Giemsa Stain is ... contains the fixative, buffer, and ... staining of blood smears. It ... bottle for ease of use ...
Our Wright stain is a dual-use stain for peripheral blood and bone marrow smears. It produces results similar to those of the Giemsa stain with a slightly greater contrast....
Medicine Products: