Navigation Links
Ovarian cancer study offers vital clues for new therapies
Date:4/21/2010

Scientists have taken a major step forward in the understanding of ovarian cancer, which could improve treatment for patients with the condition.

Researchers have found that patients with hereditary ovarian cancer whose tumours are caused by faulty genes are more likely to experience secondary tumours in their liver and spleen. This is despite the fact that their overall prognosis is better than other patients.

In non-hereditary cancer, ovarian tumours tend to remain within the lining of the abdomen and pelvis.

A University of Edinburgh study suggests that ovarian cancer patients whose tumours spread to the solid organs such as the liver and lungs should be tested for the faulty genes BRCA1 and BRCA2 to ensure they are given the most appropriate treatment.

Researchers say this would improve the detection of these faulty genes as current criteria for genetic testing may miss as many as two-thirds of ovarian cancer patients carrying faulty BRCA genes.

Patients with hereditary tumours, which account for 10 per cent of ovarian cancers, may also be suitable for trials of a new drug called olaparib, which has fewer side-effects than normal cancer treatments.

Improving the identification of BRCA mutations would help relatives of ovarian cancer patients, who may themselves be at increased risk of developing hereditary cancer.

The research is published in the Journal of Clinical Oncology.

Dr Charlie Gourley, who led the research at the University of Edinburgh, said: "We are beginning to understand the importance of tailoring cancer treatments according to the specifics of each patient's tumour. These findings demonstrate that tumours which arise because of defects in the BRCA1 or BRCA2 genes behave differently to other ovarian cancers. This information should also help us to identify the patients carrying these genetic mutations, give them the most effective treatment for their cancer an
'/>"/>

Contact: Anna Borthwick
anna.borthwick@ed.ac.uk
44-131-651-4400
University of Edinburgh
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Only women with Western Swedish breast cancer gene run higher risk of ovarian cancer
2. Pre-Diagnosis Diet Linked to Ovarian Cancer Survival
3. Study finds delay in referrals for older women with ovarian cancer
4. Foster Friess commits up to $50,000 to help TGen fight ovarian cancer
5. How to make the best decisions when at high risk for breast or ovarian cancer
6. Symptoms have little value for early detection of ovarian cancer
7. Symptoms Alone Dont Spot Ovarian Cancer Early
8. Ultrasound plus proteomic blood analyses may help physicians diagnose early-stage ovarian cancer
9. Abbott Receives European Regulatory Approval for New Ovarian Cancer Diagnostic Test
10. Research suggests link between infertility, low egg reserve, and breast/ovarian cancer gene (BRCA1)
11. Arrayit Diagnostics to Bring First Pre-Symptomatic Ovarian Cancer Blood Test to Multi-Billion Dollar Diagnostic Market in 2010
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/1/2014)... The peptide a small protein beta-amyloid is strongly associated ... unequivocal proof that this peptide is the causal agent ... main obstacle impeding such confirmation is that beta-amyloid is ... it aggregates, that is when it self-assembles to form ... with a single target, beta-amyloid alone, but with multiple ...
(Date:10/1/2014)... Physical Sciences Research Council (EPSRC) will focus on ... systems which run, for example, manufacturing plants, power ... , The research will help understand and ... systems behind our critical national infrastructure. , ... (RITICS), based at Imperial College London, is co-ordinating ...
(Date:10/1/2014)... Familylifeinsurancequotes.org has released a new blog post explaining how ... Senior citizens can qualify for affordable term life insurance ... are over 50 years old. Some term life insurance ... , Term life insurance with a simplified issue can ... life insurance during retirement is important for covering funeral ...
(Date:10/1/2014)... 2014 Lifeinsurance-policy.com has released a ... life insurance prices for smokers. , Smoking will always ... Comparing quotes is the best method to find affordable ... customers who need coverage. , Whole life insurance ... the policy. Since the coverage is permanent, the initial ...
(Date:10/1/2014)... (PRWEB) October 01, 2014 Farmington ... including a redefined mission and visual identity helping ... of partnering with them to create greater benefit ... brand that focuses on empowering customers to better ... , The crown jewel of the rebrand is ...
Breaking Medicine News(10 mins):Health News:Laying siege to beta-amyloid, the key protein in Alzheimer's disease 2Health News:£2.5 million to recognize and reduce cyber-attack threats to critical infrastructure 2Health News:Affordable Term Life Insurance - Senior Citizens Can Qualify for Coverage! 2Health News:Affordable Whole Life Insurance Premiums for Smokers! 2Health News:Farmington Company Launches Rebrand and New Positioning 2
... therapy still recommended over steroid injections, researchers say , ... the eye slowed diabetes-related eye disease, though lasers remain ... to the steroids, new research shows. , Researchers from ... and women who had diabetic retinopathy with macular edema ...
... , , WESTON, Fla., Dec. 31 ... annual meeting of shareholders on December 28, 2009 was adjourned due ... not sufficient shares present in person or by proxy to constitute ... adjourned the Annual Meeting in order to permit further solicitations of ...
... and comfort to hospice patients and their families , THURSDAY, ... help Alzheimer,s patients remember and autistic children calm down. Now, ... guitar to comfort dying patients in hospice. , Families gathered ... hymns, such as "Amazing Grace," while others ask for favorite ...
... ... it was put to the ultimate test in a double-blind, randomized study. , ... Manhasset, NY (Vocus) December 31, 2009 -- ... it was put to the ultimate test in a double-blind, randomized study. It turned out ...
... , ... a joint press release of Hiru Corporation (HIRU) and Hard to ... the finalization and completion of the purchase and sale of the ... stock basis can be found at the Pink Sheets web site ...
... Conn., Dec. 31 Metabolife, a leading brand in the weight ... Spectacular introduces, "My Resolution" a part of Metabolife,s online community dedicated ... healthier person for the New Year. , "We know ... so we created a place for individuals to share their resolutions ...
Cached Medicine News:Health News:Laser Deemed Best Treatment for Diabetic Retinopathy 2Health News:American Scientific Resources 2009 Annual Meeting of Shareholders Adjourned 2Health News:Her Music Eases the End for Dying Patients 2Health News:Her Music Eases the End for Dying Patients 3Health News:Despite Earlier Doubts, Feinstein Study Shows Fetal Transplants May Benefit Parkinson's Patients Over Age 60 2Health News:Despite Earlier Doubts, Feinstein Study Shows Fetal Transplants May Benefit Parkinson's Patients Over Age 60 3Health News:Hard To Treat Diseases (HTDS) Finalizes Sale Of Its MindUp BioResearch Division To (HIRU) 2Health News:Hard To Treat Diseases (HTDS) Finalizes Sale Of Its MindUp BioResearch Division To (HIRU) 3Health News:Hard To Treat Diseases (HTDS) Finalizes Sale Of Its MindUp BioResearch Division To (HIRU) 4Health News:Metabolife(R) Helps People Nationwide Start off the New Year Right as the Presenting Sponsor of the 2009 Brian Boitano Skating Spectacular 2Health News:Metabolife(R) Helps People Nationwide Start off the New Year Right as the Presenting Sponsor of the 2009 Brian Boitano Skating Spectacular 3
(Date:10/1/2014)... 2014  Dyadic International, Inc. ("Dyadic") (OTCQX: DYAI), ... technology used to develop and produce enzymes and ... and industrial enzymes industries, today announced the receipt ... for commercial scale production of Abengoa,s proprietary cellulase ... under Abengoa,s license agreement with Dyadic. ...
(Date:10/1/2014)...  ResMed (NYSE: RMD ), a pioneer and ... design complete sleep apnea solutions specifically for women, is launching ... a good night,s sleep. The Better Sleep ... tired is just part of living a busy life. It ... pillar of health, essential to not only living an active ...
(Date:10/1/2014)... MIAMI , Oct. 1, 2014 NeuroCall, ... Commission accreditation for its Telestroke and Teleneurology services. Dr. ... of NeuroCall, commented, "We are extremely proud that our ... Commission, as we continue to provide lifesaving support and ... of affiliated hospitals throughout the United States ...
Breaking Medicine Technology:Dyadic International Reports Licensing Payment For Commercial-Scale Production Of C1-Based Cellulase Enzymes 2Dyadic International Reports Licensing Payment For Commercial-Scale Production Of C1-Based Cellulase Enzymes 3ResMed Launches Initiative to Help Women Get Better Sleep 2ResMed Launches Initiative to Help Women Get Better Sleep 3NeuroCall Awarded Joint Commission Accreditation 2
... 8, 2011 PermaDerm™, an engineered skin substitute which ... prepared from a patient,s own skin cells, has been ... that the U.S. Department of Defense awarded more than ... of the therapeutic candidate for the treatment of severe ...
... a Carmel-headquartered software development and solutions firm has been ... 500 and mid-market businesses throughout the world since 1983. ... its extensive supply chain experience to develop supply chain ... Blue Horseshoe Intellectual Property (BHIP). Led ...
Cached Medicine Technology:PermaDermâ„¢ Receives National Media Coverage 2Software Development Firm's New Intellectual Property Group, Blue Horseshoe IP Creates Solutions to Help Customers Optimize Supply Chain 2Software Development Firm's New Intellectual Property Group, Blue Horseshoe IP Creates Solutions to Help Customers Optimize Supply Chain 3
... / gel tubes are for the ... diagnostics and for viral load determinations. ... remain stable at room temperature for ... results, it is recommended to centrifuge ...
BD Vacutainer® spray-coated K2EDTA tubes are used for whole blood hematology determinations and immunohematology testing....
We offer small and large pre-gelled Surface Electrodes suitable for EMG or EGG recordings....
We offer small and large pre-gelled Surface Electrodes suitable for EMG or EGG recordings....
Medicine Products: