Navigation Links
Ovarian cancer screening not catching early disease
Date:4/1/2009

BIRMINGHAM, Ala. The only available screening tests for ovarian cancer fail to catch early signs of the disease and often result in unnecessary surgery, said researchers at the University of Alabama at Birmingham (UAB) Comprehensive Cancer Center.

The new study looked at a screening regimen that combines ultrasound and a blood test for CA-125, a marker for women's cancer.

Results showed the combo screening caught 70 percent of the ovarian cancers in their late stages, when effective treatment options are limited.

Knowing this screening limitation means the search has intensified for a better way to detect ovarian cancer, often called the "silent killer," said Edward Partridge, M.D., director of the UAB Comprehensive Cancer Center and the lead study author.

"We still have some comparison data to review, but right now it looks like the positive predictive value of these tests is pretty low," Partridge said.

The study puts the positive predictive value for both tests at around 1.6 percent per 100 positive screening results, a remarkably low positivity rate that led to many false positives, he said. False positives are erroneous signals of cancer where there is none.

The UAB results are published April 1 in the journal Obstetrics & Genecology.

One alarming trend noted in the study is how often transvaginal ultrasound led to a high rate of unnecessary removal of the ovaries, which means no cancer was detected in these organs post-surgery.

"This data suggests that we need a better screening tool. We need a test that is more sensitive and more specific so we find the cancer earlier and we catch the biological markers that give us stronger clues," Partridge said.

The study was part of the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial (PLCO trial) and included more than 72,000 women aged 55 to 74.

The PLCO results coincide with a British study published Mar
'/>"/>

Contact: Troy Goodman
tdgoodman@uab.edu
205-934-8938
University of Alabama at Birmingham
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Doctors at Henry Ford Health System Treat Ovarian, Prostate, Lung, and Other Forms of Cancer Using Novalis Tx(TM) Platform for Image-Guided Radiosurgery
2. Catching Ovarian Cancer Early May Miss Aggressive Tumors
3. Ovarian cancers detected early may be less aggressive, questioning effectiveness of screening
4. Morphotek(R), Inc. and Eisai Corporation of North America Announce FDA Special Protocol Assessment (SPA) for Phase III Trial Evaluating Farletuzumab in Relapsed Ovarian Cancer
5. Combo Screening Doesnt Spot Early Ovarian Cancer
6. Early Detection Remains Key in Updated NCCN Guidelines for Ovarian Cancer
7. Combo of Tests Might Spot Ovarian Cancer Early
8. Biomarker Combination and Risk of Ovarian Malignancy Algorithm (Roma(TM)) Demonstrates Accuracy in Detecting Ovarian Cancer
9. Fertility Drugs Do Not Increase Ovarian Cancer Risk
10. Angiogenesis linked to poor survival in patients with rare type of ovarian cancer
11. Fujirebio Diagnostics and Abbott Agree To Develop New Ovarian Cancer Test for Abbotts Architect(R) Analyzers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/7/2015)... ... July 07, 2015 , ... ... announces the IV Tube Holder, a medical invention that prevents IV lines from ... in the world which will be worth $133 billion by 2016," says Scott ...
(Date:7/7/2015)... ... July 07, 2015 , ... An ... Consultants that discussed how innovation and technology would be the “key factors” in ... address issues of accessibility and affordability, especially in emerging and growing markets. According ...
(Date:7/7/2015)... ... July 07, 2015 , ... sweetFrog Enterprises has announced ... and provide frozen yogurt offerings at Live Nation's amphitheaters in Virginia Beach and ... site at concerts throughout the summer and brand ambassadors will offer free t-shirts ...
(Date:7/7/2015)... ... 07, 2015 , ... WiseWear®, a wearable startup that specializes ... of luxury smart jewelry called the Socialite™ collection. The product line is available ... , “The Socialite collection was crafted to inspire women to be safe, mindful ...
(Date:7/7/2015)... ... ... Owners of Green Ladies Cleaning are very pleased to announce that they are ... only be gained by votes from Madison Magazine readership. , The company says that ... use daily. Having a home cleaned with all-natural products means that residents of apartments, ...
Breaking Medicine News(10 mins):Health News:New Evidence Shows Why Hospital Weekend Effect Is So Dangerous As World Patent Marketing Introduces A New Medical Invention 2Health News:New Evidence Shows Why Hospital Weekend Effect Is So Dangerous As World Patent Marketing Introduces A New Medical Invention 3Health News:New Evidence Shows Why Hospital Weekend Effect Is So Dangerous As World Patent Marketing Introduces A New Medical Invention 4Health News:New Evidence Shows Why Hospital Weekend Effect Is So Dangerous As World Patent Marketing Introduces A New Medical Invention 5Health News:Recent Article on Pharmaceutical Innovation Highlights the Need for Creative Solutions to Common Problems, Says Medlife Pharmacy 2Health News:Recent Article on Pharmaceutical Innovation Highlights the Need for Creative Solutions to Common Problems, Says Medlife Pharmacy 3Health News:sweetFrog Mobile Trucks to Offer Froyo at Live Nation Venues 2Health News:WiseWear Unveils Luxury Smart Jewelry Line 2Health News:Environmentally-Friendly House Cleaning Company Wins Best of Madison Magazine Award 2
... Whiteboard to improve the level of patient care and streamline workflow ... makes this announcement from the 2009 Annual HIMSS Conference & Exhibition ... number 2468. , ... Chicago, IL (PRWEB) April 6, ...
... 6 Today, Craneware, Inc. (AIM: CRW.L), the ... solutions, announced an agreement with Premier ... unit of Premier Inc. Under the agreement, ... terms for Craneware financial performance software and services ...
... study uses hormone-antioxidant combo to improve odds of conception ... A hormone-antioxidant combination therapy appears to improve sperm count ... study. , The research included 60 men eligible ... either the combination treatment of clomiphene citrate and vitamin ...
... Integration and Interoperability Costs and Improve Continuation of ... Inc. (IGI) today announced the launch of the ... provides an efficient way to exchange healthcare information ... solution will allow healthcare providers to be more ...
... Security of Personal Health Information Still Major Concern ... determine how they will take advantage of the ... help jumpstart advances in health information technology (HIT), ... tools and services is also growing, according to ...
... Pharma today announced the formation of its Scientific Advisory Board, ... assist the company in the design and execution of its ... (NO) and redox biology. Dr. Joseph Loscalzo, Chairman of ... Hersey Professor of the Theory and Practice of Medicine at ...
Cached Medicine News:Health News:Orion Health Concerto Whiteboard Helps Emergency Rooms and Wards Track Patient Status 2Health News:Orion Health Concerto Whiteboard Helps Emergency Rooms and Wards Track Patient Status 3Health News:Craneware to Offer Financial Performance Solutions to Hospitals and Healthcare Providers Through Premier, the Largest U.S. Healthcare Alliance 2Health News:Craneware to Offer Financial Performance Solutions to Hospitals and Healthcare Providers Through Premier, the Largest U.S. Healthcare Alliance 3Health News:Male Infertility Treatment Boosts Sperm Count 2Health News:IGI Announces Portal Designed to Maximize Data Sharing Between Hospitals and Their Affiliated Physicians 2Health News:IGI Announces Portal Designed to Maximize Data Sharing Between Hospitals and Their Affiliated Physicians 3Health News:Deloitte Survey Finds Healthy Consumer Demand For Electronic Health Records, Online Tools and Services 2Health News:Deloitte Survey Finds Healthy Consumer Demand For Electronic Health Records, Online Tools and Services 3Health News:Deloitte Survey Finds Healthy Consumer Demand For Electronic Health Records, Online Tools and Services 4Health News:Deloitte Survey Finds Healthy Consumer Demand For Electronic Health Records, Online Tools and Services 5Health News:N30 Pharma Forms Scientific Advisory Board 2
(Date:7/7/2015)... FREMONT, Calif. , July 7, 2015  The ... and Velos, Inc. have entered into a seven year ... research nationally throughout South Korea and ... signing was accompanied by a two day joint workshop between ... Korea.  National Cancer Center President Dr. Lee ...
(Date:7/7/2015)... , Kalifornien, 7. Juli 2015 /PRNewswire/ ... Medizintechnikunternehmen, das sich der Entwicklung innovativer Geräte ... heute den Zugang von R. Michael ... Herr Kleine verfügt über eine ... Medizintechnik und Gesundheitsfürsorge. Er hat verschiedene globale ...
(Date:7/7/2015)... Md. , July 7, 2015 ... (CRO) focusing in Oncology, Vaccines, and General Medicine ... the final locked database to Heron Therapeutics, Inc. ... 3 receptor antagonist product candidate SUSTOL® (granisetron ... regimen with the IV NK 1 receptor ...
Breaking Medicine Technology:National Cancer Center of South Korea and Velos Sign Long-Term Velos eResearch Agreement 2National Cancer Center of South Korea and Velos Sign Long-Term Velos eResearch Agreement 3Sequent Medical beruft Mike Kleine in den Aufsichtsrat 2Sequent Medical beruft Mike Kleine in den Aufsichtsrat 3Accelovance Completes Trial Enrollment and Delivery of Clinical Data for Heron Therapeutics' Phase 3 Trial 2
... ALTO, Calif., Jan. 10, 2012 Varian Medical Systems (NYSE: ... a new radiotherapy treatment planning tool designed to work with ... the amount of time needed for planning advanced treatments. ... clinician must take the patient,s anatomical images and identify and ...
... Agreement allows development for potential treatment of chronic constipation ... SHPGY ), the global specialty biopharmaceutical company, announced today ... market Resolor ® (prucalopride) in the United States ... of the agreement have not been disclosed. ...
Cached Medicine Technology:Varian Medical Systems Receives FDA 510(k) Clearance for Software that Speeds Up Radiotherapy Treatment Planning 2Shire Acquires US Rights to Resolor(R) (prucalopride) 2Shire Acquires US Rights to Resolor(R) (prucalopride) 3Shire Acquires US Rights to Resolor(R) (prucalopride) 4
... false signals and contamination caused by ... Barrier Tips offer performance and economy ... (PCR(a)), radioactive isotopes, tissue culture fluids, ... , ,Promega Barrier Tips are made ...
... eliminate false signals and contamination caused ... Promega Barrier Tips offer performance and ... acids (PCR(a)), radioactive isotopes, tissue culture ... specimens. , ,Promega Barrier Tips are ...
... a safe alternative to using positive displacement ... such as PCR(a), pipetting radioactive materials and ... excellent for tissue culture, gel loading, serological ... aerosol contaminants and liquids from reaching the ...
Diamond Filter Tips play a critical role in preventing aerosol-borne contamination. Also available sterilized (no need to autoclave) and certified free of detectable RNase, DNase, DNA, RNA, and prote...
Medicine Products: