Navigation Links
Ovarian cancer finding may be a 'win-win' for at-risk women who wish to have a family
Date:4/7/2011

PORTLAND, Ore. Researchers at Oregon Health & Science University's Oregon National Primate Research Center may have good news for women at high-risk for ovarian cancer who also want to have children. The research suggests that a layer of cells, which serve as the "breeding ground" for ovarian cancer, may be removed yet allow the women to have children. This would be a vast improvement over the current prevention strategy for women at high risk for ovarian cancer: Removal of the ovaries entirely. The research is published in the current online edition of the journal Human Reproduction. It will also appear in a future printed edition of the journal.

The new treatment approach being tested at OHSU focuses on a layer of cells that surround the ovaries called ovarian surface epithelium. These cells, which have no known function, are where ovarian cancer takes root. To conduct the research, scientists washed away the ovarian surface epithelium in healthy female monkeys through minimally invasive surgery.

Following the procedure, the animals were closely observed to determine if removal of the cells changed function of the ovaries themselves. This observation revealed that the animals' ovaries produced eggs at a normal rate, as well as estrogen and progesterone in normal cyclic patterns. The procedure did not appear to affect the health of the ovaries or the overall health of the animals.

Because women with a family history of the disease are at a much higher risk for ovarian cancer themselves, many of these women choose to have their ovaries removed as a precaution. Of course for young women, this can be a major quality of life issue as the treatment prevents future childbirth and removes the primary source of a woman's estrogen.

"While additional studies are necessary, this procedure suggests that we may have found a much less invasive strategy for preventing ovarian cancer in high-risk women while at the same time maintaining fertility," said Jay Wright, Ph.D., a scientist in the Division of Reproductive Sciences at the Oregon National Primate Research Center. "This is a key finding in monkeys because their reproductive system is so similar to the human female reproductive system."


'/>"/>

Contact: Jim Newman
newmanj@ohsu.edu
503-494-8231
Oregon Health & Science University
Source:Eurekalert

Related medicine news :

1. How to make the best decisions when at high risk for breast or ovarian cancer
2. Foster Friess commits up to $50,000 to help TGen fight ovarian cancer
3. Study finds delay in referrals for older women with ovarian cancer
4. Pre-Diagnosis Diet Linked to Ovarian Cancer Survival
5. Only women with Western Swedish breast cancer gene run higher risk of ovarian cancer
6. Ovarian cancer study offers vital clues for new therapies
7. Researchers identify a new breast and ovarian cancer susceptibility gene
8. Study Makes Strides in Understanding Ovarian Cancer
9. PMH cancer researchers link ovarian hormone to breast stem cells growth
10. CA-125 change over time shows promise as screening tool for early detection of ovarian cancer
11. Early Detection of Ovarian Cancer Moves Closer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... June 25, 2016 , ... Experts from the ... AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes Convention Center in ... topics including advance care planning, healthcare costs and patient and family engagement. , ...
(Date:6/25/2016)... ... June 25, 2016 , ... The temporary closing of Bruton Memorial Library on June ... , brings up a new, often overlooked aspect of head lice: the parasite’s ability to ... is not a common occurrence, but a necessary one in the event that lice have ...
(Date:6/25/2016)... ... ... First Choice Emergency Room , the largest network of independent freestanding emergency ... its new Mesquite-Samuell Farm facility. , “We are pleased to announce Dr. Ogunleye ... M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. , Dr. Ogunleye ...
(Date:6/25/2016)... ... June 25, 2016 , ... Dr. Calvin Johnson has ... he has implemented orthobiologic procedures as a method for treating his patients. The ... first doctors to perform the treatment. Orthobiologics are substances that orthopaedic surgeons use ...
(Date:6/25/2016)... ... 2016 , ... Conventional wisdom preaches the benefits of moderation, whether it’s a ... the bar too high can result in disappointment, perhaps even self-loathing. However, those who ... , Research from PsychTests.com reveals that behind the tendency to set ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 2016 Research and Markets has announced ... report to their offering. ... a favourable commercial environment for MedImmune to enter. The US ... will serve to drive considerable growth for effective anti-influenza medications. ... cap sales considerably, but development is still in its infancy. ...
(Date:6/23/2016)...  Astellas today announced the establishment of Astellas Farma Colombia (AFC), a new affiliate with operations headquartered in ... . ... ... ... Astellas ...
(Date:6/23/2016)... , June 23, 2016 Research ... "Surgical Procedure Volumes: Global Analysis (United States, China, Japan, ... report to their offering. ... tool for healthcare business planners, provides surgical procedure volume ... surgery trends with an in-depth analysis of growth drivers ...
Breaking Medicine Technology: