Navigation Links
Otherwise Healthy Older Men Undertreated for Prostate Cancer: Study
Date:9/29/2011

THURSDAY, Sept. 29 (HealthDay News) -- Men over 75 with prostate cancer who are otherwise healthy are being undertreated for their condition, according to a new study.

Meanwhile, younger men with prostate cancer who are affected by other health problems -- or "co-morbid" conditions -- are being treated for their cancer, but not responding as well as expected, University of California, Los Angeles researchers found.

"This study suggests that men with certain medical conditions are being treated just as aggressively for their prostate cancer as men who are healthy, even though they are more likely to die of non-prostate cancer causes. Conversely, men over 75 are not being aggressively treated when they may, in fact, fare better than younger men with complicating health issues," the study's first author, Dr. Karim Chamie, a postdoctoral fellow in urologic oncology and health services research, said in a UCLA news release.

"There are individual medical problems that impact survival much more so than simply being 75 years of age," Chamie added.

In conducting the study, the researchers examined the medical records of more than 1,000 men diagnosed with prostate cancer who were being treated at a federally subsidized Veterans Affairs Medical Center.

The researchers specifically chose the VA hospital in order to eliminate speculation that treatment decisions were also bottom-line cost decisions. "This really speaks to the underlying psychology of physicians and how they manage patients with prostate cancer," Chamie explained in the news release.

Although men with prostate cancer who were also being treated for another co-existing medical issue (such as chronic obstructive pulmonary disease, diabetes and peripheral vascular disease) had lower survival rates than other men, their cancer was treated just as aggressively, the investigators found.

The study revealed that of the roughly two-thirds of men who underwent aggressive treatment for prostate cancer, only 16 percent who had no other health problems died of other causes after 10 years.

In contrast, 35 percent of men who also had diabetes died of causes not related to their cancer after 10 years. Meanwhile, the study showed 50 percent of diabetic men who had organ damage related to the condition died within that time frame for reasons not cancer-related.

Similarly, 49 percent of men who also had peripheral vascular disease who were treated for their cancer were dead within 10 years, and 65 percent of men with moderate to severe chronic obstructive pulmonary disease also died. In both of those situations, the men died for reasons not related to cancer, according to the findings published in the Sept. 21 online edition of the Journal of General Internal Medicine.

"I think some physicians may think that a man with only one co-morbid condition is healthier than he may in fact be," said Chamie. "Some patients, even those with just a single co-morbid condition, might benefit from surveillance, as they may die as a result of other causes before their prostate cancer and avoid being exposed to some of the debilitating side effects of treatments."

In taking the age of the men into account, however, the study revealed that only about 25 percent of 75-year-olds were being treated for their prostate cancer -- even though they had a 58 percent chance of surviving another decade.

"This study suggests that while physicians use patient age of 75 as a very strong cue to avoid overtreatment of men with prostate cancer, they are less likely to integrate certain co-morbidities into prostate cancer decision making," concluded Dr. Mark S. Litwin, chairman of the urology department and a researcher at UCLA's Jonsson Comprehensive Cancer Center, in the release. "There are some medical conditions that portend a poor prognosis and should therefore be taken into consideration in the decision-making process."

More information

The U.S. National Library of Medicine has more about prostate cancer.

-- Mary Elizabeth Dallas

SOURCE: University of California Los Angeles, news release, Sept. 26, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Helicobacter pylori infection linked to decreased iron levels in otherwise healthy children, according to research at UTHealth
2. Antioxidants Not Behind Red Wines Healthy Effect on Heart: Study
3. Good Moms Seem to Help Poor Kids Become Healthy Adults
4. Exercise can produce healthy chatter between bone, fat and pancreatic cells
5. Healthy Living Can Cut Chances of Developing Diabetes
6. Healthy Habits Can Fend Off the Freshman 15
7. Thank Neanderthals for That Healthy Immune System, Scientists Say
8. Kids of Unhealthy, Disadvantaged Moms More Likely to Be Sickly
9. Long-term, intimate partnerships can promote unhealthy habits
10. Healthy Behaviors Will Help You Live Longer: CDC
11. Cartoon Characters Prod Kids to Nag for Unhealthy Foods
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Otherwise Healthy Older Men Undertreated for Prostate Cancer: Study
(Date:8/20/2017)... ... August 20, 2017 , ... State Farm Neighborhood Assist® has named The ... a $25,000 grant. If the initiative wins, Gals Lead – Dream Queen Foundation’s signature ... Tri-County area of St. Mary’s, Calvert and Charles Counties. The program could potentially impact ...
(Date:8/19/2017)... ... August 18, 2017 , ... Paragon and ... database to help the cannabis industry move towards greater legitimacy. By incorporating IOTA’s ... faster technology with lower fees. Paragon will build a fully verifiable database to ...
(Date:8/19/2017)... (PRWEB) , ... August 19, 2017 , ... ... with contemporary illustrations of breastfeeding mothers. These illustrations show the diversity of ... in prints in a wide range of sizes. These illustrations are also available ...
(Date:8/19/2017)... ... August 19, 2017 , ... “Congratulations! It's A Boy! God’s Gift: A Story ... parents and God. “Congratulations! It's A Boy! God’s Gift: A Story of Love” is ... Island, New York. , Published by Christian Faith Publishing, Dale Anthony and Rachael Anthony’s ...
(Date:8/18/2017)... York, New York (PRWEB) , ... ... ... International Courier, LLC, d/b/a Quick International, LLC (“Quick”), a highly specialized asset-light ... announced it has entered into a definitive agreement to purchase Unitrans International ...
Breaking Medicine News(10 mins):
(Date:8/8/2017)... DUBLIN, Aug. 8, 2017   ... $3.12 diluted (GAAP) loss per share from continuing operations ... Products revenues increased 16 percent to $110 million ... increased 27 percent to $161 million ... (EPS) from continuing operations increased 8 percent to $0.93 ...
(Date:8/7/2017)... 2017  Diplomat Pharmacy, Inc. (NYSE: DPLO), the nation,s largest ... June 30, 2017.  All comparisons, unless otherwise noted, are to ... Second Quarter 2017 Highlights include: ... an increase of 3.5% Total prescriptions dispensed ... of 7.5% versus 7.6% Gross profit ...
(Date:8/3/2017)...  Opioid addiction and other drugs of abuse, blood ... threatening outcomes, were problems taken on directly as laboratory ... support them, met this week. This according to Kalorama ... of abuse, procalcitonin and acute kidney injury were key ... meeting in San Diego, CA. ...
Breaking Medicine Technology: