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Other stomach microbiota modulate resistance to H. pylori-driven ulcers
Date:3/25/2013

vated amounts of Clostridia, bacteria known to prevent inflammation in the intestine," says Ottemann. Thus, the Clostridia may be key to dampening H. pylori pathology, although that remains to be determined, she says.

Ottemann says that this research may lead to predicting future H. pylori disease, including ulcers and gastric cancer -- which has few treatment options and high mortality -- based on stomach microbiota.

"After we determine which microbes underlie H. pylori disease outcomes, we could test whether H. pylori-infected people harbor those particular bacteria, and target them for curing," says Ottemann. Alternatively, such people could receive the protective bacteria as probiotics. The latter might be a superior option, because while prone to ulcers in middle and advanced age, people who harbor H. pylori are less likely to get esophageal cancer and asthma.


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Contact: Garth Hogan
ghogan@asmusa.org
American Society for Microbiology
Source:Eurekalert

Page: 1 2

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