Navigation Links
Other highlights in the Jan. 8 JNCI
Date:1/8/2008

ine its role of NRP2 in cancer growth and cell growth, death, and migration.

NRP2 was expressed in primary and metastatic cancers but was not detectable in surrounding non-cancerous tissue. Blocking NRP2 reduced cell growth, migration, and invasiveness, as well as tumor growth. The researchers also demonstrated that inhibiting NRP2 was effective in treating tumors in mice.

The use of anti-NRP2 therapeutic targeting in conjunction with anti-VEGF therapy may improve on existing antiangiogenesis treatments and may provide a unique opportunity to circumvent the ability of NRP2-expressing tumors, such as colorectal cancers, to grow and metastasize, the authors write.

In an accompanying editorial, Giovanna Tosato, M.D., of the National Cancer Institute in Bethesda, Md., and colleagues discuss how this groundbreaking work by Ellis and colleagues furthers the understanding of the role of NRP2 in colon cancer.

This is welcome new information. Let us hope that targeting neuropilin-2 can hit double punches against the cancer microenvironment and the cancer itself, the editorialists write.

Contact:

Mouse Model of Rare Disorder Shows Parallel to Human Kidney Cancer

A new mouse model may be useful for studying kidney cancer development.

Birt-Hogg-Dub (BHD) syndrome is a rare genetic disorder that is associated with an increased risk of kidney cancer. Patients with BHD carry mutations in the BHD tumor suppressor gene. Masaya Baba, M.D., Ph.D., of the National Cancer Institute in Frederick, Md., used a knockout mouse model to examine the role of the BHD ge
'/>"/>

Contact: Liz Savage
jncimedia@oxfordjournals.org
301-841-1287
Journal of the National Cancer Institute
Source:Eurekalert

0

GOOD

Page: 1 2 3 4

Related medicine news :

1. New study: US ranks last among other industrialized nations on preventable deaths
2. US ranks last among other industrialized nations on preventable deaths
3. Varian Medical Systems Receives FDA 510(k) Clearance for RapidArc(TM) Radiotherapy Technology
4. The prevalence and impact of arthritis and other rheumatic conditions in the United States
5. Fight against hay fever and other allergies helped by new immune system discovery
6. High triglycerides, other cholesterol raise risk of stroke
7. Class of Chemotherapy Drugs Helps Certain Breast Cancer Patients
8. Chemotherapy and tamoxifen reduce risk of second breast cancer
9. Other highlights in the Dec. 25 JNCI
10. Alexian Brothers Hospital Network Receives American Stroke Associations Get with the Guidelines Silver Achievement Award
11. Alexian Brothers Hospital Network Receives American Stroke Associations Get With the Guidelines Achievement Award
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/14/2009)... Professional HealthCare at Home now provides in-home caregivers who have ... provides home nursing, rehab therapy, caregiver, and hospice services to ... ... Walnut Creek, CA (PRWEB) December 14, 2009 -- Professional ... of total home health care, including nursing, rehab, personal caregiver ...
(Date:12/14/2009)... WASHINGTON, Dec. 14 Following is a ... Tobacco-Free Kids: ,, (Logo: http://www.newscom.com/cgi-bin/prnh/20080918/CFTFKLOGO ) ,, ... by the National Institute of Drug Abuse shows ... in reducing youth smoking, but declines have slowed ... the decade. In especially troubling news, the ...
(Date:12/14/2009)... of urban teenage girls may acquire at least one ... years of becoming sexually active, according to an Indiana ... , The study appears in the December 2009 issue ... , The researchers followed 381 girls enrolled at ages ... with the organisms that cause chlamydia, gonorrhea and trichomoniasis ...
(Date:12/14/2009)... U.S. Food and Drug Administration (FDA) announced publication ... practices (cGMPs) for the production of positron emission ... document describing acceptable approaches that would enable PET ... proposed regulation. , "We are pleased that ... are so important to the diagnosis and treatment ...
(Date:12/14/2009)... by Novartis Oncology, was conducted independently for CURE magazine among ... facing patients today and better identify their needs. The Leukemia ... the Life Raft Group and GIST Support International react to ... of this release. , ... East ...
Breaking Medicine News(10 mins):Health News:Caregivers with Professional HealthCare at Home Now Certified by the Alzheimer's Association 2Health News:New Survey Shows Slow Decline in Youth Smoking, Troubling Increase in Smokeless Tobacco Use - Congress, States Must Step Up Tobacco Prevention Efforts 2Health News:New Survey Shows Slow Decline in Youth Smoking, Troubling Increase in Smokeless Tobacco Use - Congress, States Must Step Up Tobacco Prevention Efforts 3Health News:New Survey Shows Slow Decline in Youth Smoking, Troubling Increase in Smokeless Tobacco Use - Congress, States Must Step Up Tobacco Prevention Efforts 4Health News:New Survey Shows Slow Decline in Youth Smoking, Troubling Increase in Smokeless Tobacco Use - Congress, States Must Step Up Tobacco Prevention Efforts 5Health News:IU study: Half of urban teen girls acquire STIs within 2 years of first sexual activity 2Health News:SNM applauds FDA's issuing of new drug manufacturing requirements 2Health News:New Survey Highlights the Challenges of People Living with Rare Cancer 2Health News:New Survey Highlights the Challenges of People Living with Rare Cancer 3Health News:New Survey Highlights the Challenges of People Living with Rare Cancer 4Health News:New Survey Highlights the Challenges of People Living with Rare Cancer 5
... in 100 11-year-olds had taken a Class A drug, such ... 15-year-olds// have taken hard drugs. There is a rise in ... such as cocaine which has created a lot of trouble ... out among England's 3.4 million secondary pupils. Despite undertaking multi-million-pound ...
... noise, and do not like it much! According to a ... face an increased risk of suffering a heart attack. ... middle-aged adults, living on high-traffic roads and amidst ... suffering heart attack, than those who lived in tranquil surroundings. ...
... though mental disorders are said to account for a ... have been undertaken to assess// this assumption in the ... part of the WHO World Mental Health (WMH) Survey ... adults was done in Lebanon between September, 2002, and ...
... The new low nicotine Quest? cigarettes seems to have ... to a study conducted by researchers// at the Transdisciplinary ... School of Medicine.Results of the study have been published ... ,The author of this study, Caryn Lerman, PhD, Associate ...
... was accused of subjecting patients to unwarranted fertility treatments, ... by the General Medical Council. , ,Professor Craft, ... consistent in his response, of conducting treatments in the ... any of the charges leveled against him. ...
... study conducted by Columbia University Medical Center has ... in osteoarthritis, could be effective// in the treatment ... drug treatment with Cox-2 inhibitors or surgery was ... chronic shoulder pain. ,Approximately 1.5 million ...
Other Medicine News:Health News:A National Survey Revealed That Mental Disorders Are Common In Lebanon 2Health News:Sodium Hyaluronate Shows Promise In Treatment Of Shoulder Pain 2
(Date:12/14/2009)... Zargis Medical Corp., a majority-owned subsidiary of Speedus ... from Siemens Corporate Research (NYSE: SI ... its award-winning Zargis Cardioscan(TM) system on Amazon.com, America,s ... Bluetooth®-enabled electronic stethoscope were jointly named Popular ... the Year." Cardioscan is the world,s first ...
(Date:12/14/2009)... 14 Greenway Medical Technologies, Inc. ... Prime Suite (®) 2011, is ... EHR, additionally certified for Child Health and ... Prime Suite 2011 achieved the higher ... offered by the Certification Commission for Health ...
(Date:12/14/2009)... Gibraltar Associates, a leading public ... domestic communications and issues management, today announced ... PositiveID Corporation (Nasdaq: PSID ) to ... of record. Gibraltar Associates will conduct media ... the Company on its public relations programs. ...
Breaking Medicine Technology:Zargis Cardioscan 'The Intelligent Stethoscope' Now Available on Amazon.com 2Greenway Medical Technologies' PrimeSuite 2011 Receives CCHIT 2011 Comprehensive Certification 2Greenway Medical Technologies' PrimeSuite 2011 Receives CCHIT 2011 Comprehensive Certification 3Greenway Medical Technologies' PrimeSuite 2011 Receives CCHIT 2011 Comprehensive Certification 4Gibraltar Associates Named Agency of Record for Health Information and Diagnostic Provider PositiveID Corporation 2Presidential Towers Donates Apartment to the University of Illinois Medical Center 54638 1Presidential Towers Donates Apartment to the University of Illinois Medical Center 54638 2Nonsurgical Technique Can Take Years Off the Appearance of Aging Eyes 54634 1Nonsurgical Technique Can Take Years Off the Appearance of Aging Eyes 54634 2Nonsurgical Technique Can Take Years Off the Appearance of Aging Eyes 54634 3PharmaTelevision Launches the First Daily News Show for the Life Sciences Industry 13593 1PharmaTelevision Launches the First Daily News Show for the Life Sciences Industry 13593 2PharmaTelevision Launches the First Daily News Show for the Life Sciences Industry 13593 3PharmaTelevision Launches the First Daily News Show for the Life Sciences Industry 13593 4
... 18 Forty-two leading U. S. scientists and specialists gathered at a ... health and national economy from outbreaks of dangerous zoonotic diseases, the FAZD ... innovations: , , , ... Box" on every American kitchen table that detects highly contagious and dangerous ...
... ASPS Study Suggests Nutritional Supplements Prior to ... Identifying,malnutrition before surgery in massive weight ... surgical complications, accelerate,wound healing, improve scar quality ... study in the December issue of Plastic ...
Other Medicine Technology:42 Top U.S. Scientists and Specialists Explore Cutting-Edge Innovations to Defend America From Dangerous Zoonotic Diseases 2Plastic Surgeons Warn of Malnutrition in Body Contouring Patients 2
The complete performance package. Precision handling. Stable platform for device delivery. Enhanced backup support. Unique braid technology. Improved curve retention. Smooth PTFE liner....
The soft tip sheath design for smooth delivery and retrieval of Constellation advanced mapping basket catheters....
Fast-Cath, Maximum, Maximum Xtra, and Maximum ACT introducers represent the largest line of standard and specialty hemostasis introducers in the world....
A steerable diagnostic catheter with optimal maneuverability...
Medicine Products: