Navigation Links
Osteoporosis Drugs' Safety Subject of FDA Panel
Date:9/9/2011

By Steven Reinberg
HealthDay Reporter

FRIDAY, Sept. 9 (HealthDay News) -- Experts convened by the U.S. Food and Drug Administration were to meet Friday to discuss problems linked to long-term use of bone-building drugs such as Fosamax, Actonel, Boniva and Reclast.

These drugs, known as bisphosphonates, are taken to prevent fractures related to postmenopausal osteoporosis. But researchers have linked long-term use with a small risk of unusual fractures of the thigh bone, death of the jawbone (osteonecrosis of the jaw) and possibly esophageal cancer.

Members of two FDA advisory committees are expected to weigh the drugs' risks and benefits and possibly come up with new recommendations regarding their use. According to the FDA, in 2009 more than 5 million prescriptions were filled for bisphosphonates, which inhibit bone loss.

Dr. Elizabeth Shane, past president of the American Society for Bone and Mineral Research, who is scheduled to testify before the committee, said reports linking bisphosphonates with atypical fractures and osteonecrosis of the jaw are "extremely rare, when considered in the context of how many people take bisphosphonates for osteoporosis." She was "less certain about the esophageal cancer issue," she added.

While these side effects shouldn't be downplayed, "when you consider the number of very dangerous, life-threatening fractures that are prevented by these drugs, the benefits dwarf the side effects," said Shane, also a professor of medicine at Columbia University in New York City.

However, she said bisphosphonates should only be prescribed to those at the highest risk of fracture. "In the past we might have used them in people who aren't at such high risk of fracture in the hope that they would prevent fractures down the line," she said. "We have moved to targeting people at high short-term risk, which means in the next five to 10 years."

According to Shane, the ab
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. New study highlights what works in osteoporosis treatment
2. Program announced for 1st Middle-East & Africa Osteoporosis Meeting
3. Preliminary program announced for 2nd Asia-Pacific Osteoporosis & Bone Meeting
4. Gene combinations are found to be related to hip osteoporosis in postmenopausal women
5. Study links long-term use of osteoporosis drugs to unusual fractures
6. An extra 5 years of life an unexpected benefit of osteoporosis treatment
7. Researchers discover age of onset of puberty predicts adult osteoporosis risk
8. Loyola physician helps develop national guidelines for osteoporosis
9. New Osteoporosis Screening Recommendations Issued
10. Belly fat puts women at risk for osteoporosis
11. Taking a break from osteoporosis drugs can protect bones
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Osteoporosis Drugs' Safety Subject of FDA Panel 
(Date:5/29/2015)... Displays and Exhibits’ has recently aligned with a ... hanging signs ; making what was formerly an elite ... ceiling rigging points at a usual height of 16’-20’ are ... These signs are very unique and more visible than the ... and dismantle labor and rigging the costs far outweigh the ...
(Date:5/29/2015)... “In the current environment of ... regulations, we provide education that will help practitioners ... suffering from pain, within the boundaries of the ... of rehabilitation medicine and President/Medical Director of the ... , A new flight of PAINWeekEnd Regional Conferences ...
(Date:5/29/2015)... Based in St. Louis, Missouri La La Land Shirts ... couple of months now and are really helping spread awareness ... not misbehaving, I have Autism, please be understanding” is actually ... child in order to start a conversation and ultimately lead ... raising awareness through the autism awareness shirts which can be ...
(Date:5/29/2015)... Ready to hit the road? Before embarking ... to get their vehicles ready. With handicapped vehicles, there are ... Systems (ADS) is ready to help drivers get their handicapped ... road trips. , When planning for the big trip, drivers ... the trip goes smoothly and they are prepared for all ...
(Date:5/29/2015)... What does community do? , According to a ... to plant gardens, to teach young people, to laugh, ... issues. Community invites everyone to help improve lives for ... Does" was commissioned by The Denver Foundation, the largest ... the foundation’s Annual Celebration in May. At just over ...
Breaking Medicine News(10 mins):Health News:Displays and Exhibits Announces New Hanging Sign Supplier 2Health News:PAINWeekEnd Kansas City: Pain Management CME for the Main Street Practitioner 2Health News:La La Land Shirts Is Busy Spreading Autism Awareness with Complimentary Shipping on Their New Shirt 2Health News:Advanced Driving Systems Offers Tips for Summer Road Trips 2Health News:Advanced Driving Systems Offers Tips for Summer Road Trips 3Health News:What Community Does: A New Video from The Denver Foundation 2
... HighPoint Solutions LLC,a premier provider of business-driven ... develop an Incentive Compensation Plan for a new ... review.,With the project,s completion targeted for late summer ... motivate the field sales force and ensure the,alignment ...
... House expected to vote on bill this evening. , ... Alexandria, Va. ... Drug Stores (NACDS), endorsed a House bill, H.R.6331, the Medicare ... several provisions of critical importance to chain pharmacies and the patients they ...
... largest health community on the web, and HealthCare.com partner to ... , ... San Francisco, CA and Miami, ... the largest health community on the web, and HealthCare.com, Inc. ...
... shows increase in Social Security Disability Insurance recipients; time-intensive process of ... says Allsup , ... Belleville, Ill. (Vocus) June 25, ... Disability Insurance (SSDI) benefits continued to grow in 2007. This ...
... new classified assessment that explores how climate change could ... causing political instability, mass movements of refugees, terrorism, or ... The House Intelligence Committee is scheduled to be briefed ... While the assessment itself is ...
... are the workhorses of our cells. They help to digest ... and literally shape our body from top to toe. Proteins ... of enzymes, which are important in the creation of anything ... possibilities are virtually without limit. , To take advantage ...
Cached Medicine News:Health News:HighPoint Solutions Develops Novel Incentive Compensation Plan for New Benign Prostatic Hyperplasia (BPH) Product 2Health News:NACDS Praises House Legislation to Delay Medicaid Cuts, Aid Pharmacies in Treating Patients 2Health News:MedHelp Launches Healthcare Provider Search Powered by HealthCare.com 2Health News:MedHelp Launches Healthcare Provider Search Powered by HealthCare.com 3Health News:SSDI Recipients Ask: When Do I Get My Benefits? 2Health News:SSDI Recipients Ask: When Do I Get My Benefits? 3Health News:Climate change may challenge national security, classified report warns 2Health News:Climate change may challenge national security, classified report warns 3Health News:1 step closer to green chemistry and improved pharmaceuticals 2
(Date:5/29/2015)... 2015 /CNW/ - Alliance Principle Ingredients/Neutrical Solutions Inc., in ... product Galenic Health Ginger in Bentonite (NPN 80053535) ... and children. The product currently contains levels of ... acceptable limits for adult dosing. Ginger ... and disturbances. Alliance Principle Ingredients / Neutrical Solutions ...
(Date:5/29/2015)... 29, 2015  Hologic, Inc. (NASDAQ: HOLX ) ... new, five-year secured credit agreement consisting of a $1.5 ... credit facility. Hologic has borrowed $0.175 billion ... and the Term Loan to pay off the Company,s ... principal amount outstanding of $1.69 billion as of March ...
(Date:5/29/2015)... 29, 2015  Today, UL LLC, a global ... provider of electronic quality management systems (EQMS) and ... will leverage the strengths of both organizations to ... implementation and comprehensive advice and guidance for successful ... capabilities to UL,s strength in regulatory services and ...
Breaking Medicine Technology:Hologic Enters into Five-Year Secured Credit Agreement 2Hologic Enters into Five-Year Secured Credit Agreement 3UL and MasterControl collaborate to provide medical manufacturers full service QMS and Regulatory Submissions support 2UL and MasterControl collaborate to provide medical manufacturers full service QMS and Regulatory Submissions support 3
... FRANKLIN LAKES, N.J., Sept. 8 BD (Becton, Dickinson and ... company, announced today that it will present at the 2010 ... 1:35 p.m. EDT. A live webcast of BD,s ... www.bd.com/investors and will be available for replay through ...
... Sept. 8 STAAR Surgical Company (Nasdaq: ... of phakic intraocular lenses, today announced that the Visian ... than 40 presentations by leading ophthalmologists at meetings prior ... of Cataract and Refractive Surgeons (ESCRS) held in Paris, ...
Cached Medicine Technology:STAAR Surgical Launches New Visian ICL™ Product Line Extensions at ESCRS 2STAAR Surgical Launches New Visian ICL™ Product Line Extensions at ESCRS 3STAAR Surgical Launches New Visian ICL™ Product Line Extensions at ESCRS 4STAAR Surgical Launches New Visian ICL™ Product Line Extensions at ESCRS 5STAAR Surgical Launches New Visian ICL™ Product Line Extensions at ESCRS 6
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: