Navigation Links
Ortho Biotech Announces NDA Submission for Trabectedin for the Treatment of Relapsed Ovarian Cancer
Date:11/20/2008

iarrhea (26% versus 19%);
  • Liver enzyme (transaminase) elevations were more common in the combination arm, but were generally reversible and not associated with evidence of chronic liver damage or other clinical consequences. These included increased alanine aminotransferase (55% versus 9%) and increased aspartate aminotransferase (40% versus 10%); and
  • Fatigue (46% versus 36%).
  • Additionally, commonly associated DOXIL adverse events, such as hand-foot syndrome (HFS) and stomatitis, occurred in fewer patients receiving the combination compared to DOXIL alone (24% versus 54% and 20% versus 33%, respectively).

    About Trabectedin

    Trabectedin is a novel cytotoxic antitumor agent that was originally derived from the Caribbean tunicate, Ecteinascidia turbinate ("sea squirt"). The compound is now produced synthetically. Trabectedin binds to the minor groove of DNA, interfering with cell division and genetic transcription processes and DNA repair machinery. Trabectedin is currently in Phase III development in ovarian cancer and to expand its uses in sarcoma.

    According to the licensing agreement, PharmaMar has rights to market the compound in Europe and Japan, while Ortho Biotech Products, L.P. has marketing rights for the product in the rest of the world.

    About Ortho Biotech Products, L.P.

    Ortho Biotech Products, L.P. is a leading biopharmaceutical company devoted to helping improve the lives of patients with cancer and with anemia due to multiple causes, including chronic kidney disease. Since it was founded in 1990, Ortho Biotech and its worldwide affiliates have earned a global reputation for researching, manufacturing and marketing innovative products that enhance patients' health. Located in Bridgewater, N.J., Ortho Biotech is an established market leader in anemia
    '/>"/>

    SOURCE Ortho Biotech Products, L.P.
    Copyright©2008 PR Newswire.
    All rights reserved

    Page: 1 2 3 4

    Related medicine news :

    1. New Orthopedic Oncology Fellowship Program at Mount Clemens Brings Highly Trained Surgeons to State
    2. Ferring Pharmaceuticals Promotes William Garbarini to Vice President of New Orthopaedics and Urology Business Unit
    3. Dental Implants Effective for Orthodontic Treatment
    4. Hanger Orthopedic Group, Inc. Receives Favorable New Code for WalkAide
    5. Zimmer Holdings to Collaborate with the American Orthopaedic Association for Funding Post-Graduate Medical Education
    6. Dr. Ron Greenspan has Been Selected for the 2008 Best of San Diego Award in the Orthodontists Category by the U.S. Local Business Association
    7. Orthodontists Offer Sweet Incentives for Tricky Halloween Treats
    8. Hanger Orthopedic Group, Inc. Exceeds Estimates on a 10% Sales Increase and a 28% EPS Increase to $0.23 for the Third Quarter 2008
    9. Archus Orthopedics Performs First Facet Replacement Procedure With an Artificial Disc
    10. Hanger Orthopedic Group, Inc. Announces Underwritten Public Offering by Shareholder
    11. Amy Street, Certified Prosthetist and Orthotist, Joins BridgePoint Medical Partner, Charlotte Orthotic and Prosthetic Center (COPC)
    Post Your Comments:
    *Name:
    *Comment:
    *Email:
    (Date:9/1/2015)... ... September 01, 2015 , ... ... for the treatment of androgenic alopecia in adults, announces Miami-based medical device manufacturer, ... cap, while also demonstrating its safety when used at home to combat hair ...
    (Date:9/1/2015)... ... September 01, 2015 , ... The Lymphoma ... innovative lymphoma research and serving the lymphoma community through a comprehensive series of ... it Red for Lymphoma awareness initiative, the nation’s premier and most high-profile lymphoma ...
    (Date:9/1/2015)... ... 01, 2015 , ... Horizon Blue Cross Blue Shield of New Jersey (BCBSNJ) ... the LATINA Style 50 Report that recognizes companies that provide the best career opportunities ... BCBSNJ climbs from number 24 to 21 of the 50 Best Companies for Latinas. ...
    (Date:9/1/2015)... (PRWEB) , ... September 01, 2015 , ... ... and collaboration, announces Splashtop Business for Remote Support , a solution optimized ... solution. Unhappy with the escalating renewal prices and inadequate customer services of ...
    (Date:9/1/2015)... ... September 01, 2015 , ... ... announced that Edge Information Management has been granted continued accreditation based on ... (BSCC). , “Achieving and maintaining this accreditation takes the involvement and ...
    Breaking Medicine News(10 mins):Health News:Capillus82™ Laser Therapy Cap Receives FDA Clearance for Treatment of Hair Loss 2Health News:Lymphoma Research Foundation Recognizes National Blood Cancer Awareness Month with Light it Red for Lymphoma Campaign 2Health News:Lymphoma Research Foundation Recognizes National Blood Cancer Awareness Month with Light it Red for Lymphoma Campaign 3Health News:Horizon Blue Cross Blue Shield of New Jersey Named One of the 50 Best Companies for Latinas by Latina Style Magazine 2Health News:Horizon Blue Cross Blue Shield of New Jersey Named One of the 50 Best Companies for Latinas by Latina Style Magazine 3Health News:Splashtop Launches Splashtop Business for Remote Support, the Simple, Reliable, and Cost-Effective Solution for MSPs and IT Professionals 2Health News:Splashtop Launches Splashtop Business for Remote Support, the Simple, Reliable, and Cost-Effective Solution for MSPs and IT Professionals 3Health News:Splashtop Launches Splashtop Business for Remote Support, the Simple, Reliable, and Cost-Effective Solution for MSPs and IT Professionals 4Health News:Edge Information Management Granted Continued NAPBS Accreditation 2Health News:Edge Information Management Granted Continued NAPBS Accreditation 3
    ... method has been developed by UK based scientists which will ... of anti-rejection drugs are used for cell transplant as at ... ,But the method developed by doctors at Oxford's Churchill ... as islets from a donated pancreas in highly sterile conditions, ...
    ... of the opinion that interstellar dust coming into our solar ... The results have exceeded all expectations, according to Donald Brownlee, ... investigator, or lead scientist, for Stardust. ‘It's a huge success. ... there are small ones’, he said. ,According ...
    ... has been built by Australian scientists which is reported to ... ESA for its Moon mission. This brings a manned mission ... is used by ion engines to accelerate a beam of ... ,Tests on a prototype at ESA’s Electric Propulsion Laboratory in ...
    ... Advanced Nursing says expresses deep concern about the persisting reality ... ,Professor Jill Macleod Clark from Southampton University says ... change, the basic problems identified by Eve Bendall in a ... reprinted in the 30th Anniversary Issue of the Journal, had ...
    ... and converts raw data into meaningful ones? But now ... reveals the detailed process in the journal Neuron. //When ... is activated and tries to fit everything together like ... of an image, which the person observes and comprehends. ...
    ... soon have a vaccine to combat a disease (cervical cancer) ... had submitted details of a cervical cancer vaccine, // ... of infection with the human papilloma virus (HPV) to the ... vaccine, developed by GlaxoSmithKline wound soon be approved for use ...
    Cached Medicine News:Health News:What nurses learn is not what they practice 2Health News:Understanding “The Brain 2Health News:Cervical Cancer Vaccine Show Promise In Prevention 2
    (Date:9/1/2015)... Calif. and BRUSSELS ... AMGN ) and UCB (Euronext Brussels: UCB) today ... evaluating effect of RomosozUmab Compared with Teriparatide in ... fracture pReviously treated with bisphosphonatE therapy). The study ... significant difference in favor of romosozumab in the ...
    (Date:9/1/2015)... Sept. 1, 2015 Emerus Holdings, a ... emergent, inpatient and diagnostic care in partnership with ... a definitive agreement to receive a strategic investment ... a leading health care investment firm. ... patient-centric acute episodic and ambulatory clinical services to ...
    (Date:9/1/2015)... IRVINE, Calif. , Sept. 1, 2015  Edwards ... in the science of heart valves and hemodynamic monitoring, ... Fargo Healthcare Conference at the Hyatt Regency Boston in ... 9, 2015. Michael A. Mussallem , ... keynote lunch speaker followed by a company discussion with ...
    Breaking Medicine Technology:Amgen And UCB Announce Positive Top-Line Results From Open-Label Phase 3 Study Of Romosozumab Compared With Teriparatide 2Amgen And UCB Announce Positive Top-Line Results From Open-Label Phase 3 Study Of Romosozumab Compared With Teriparatide 3Amgen And UCB Announce Positive Top-Line Results From Open-Label Phase 3 Study Of Romosozumab Compared With Teriparatide 4Amgen And UCB Announce Positive Top-Line Results From Open-Label Phase 3 Study Of Romosozumab Compared With Teriparatide 5Amgen And UCB Announce Positive Top-Line Results From Open-Label Phase 3 Study Of Romosozumab Compared With Teriparatide 6Amgen And UCB Announce Positive Top-Line Results From Open-Label Phase 3 Study Of Romosozumab Compared With Teriparatide 7Amgen And UCB Announce Positive Top-Line Results From Open-Label Phase 3 Study Of Romosozumab Compared With Teriparatide 8Amgen And UCB Announce Positive Top-Line Results From Open-Label Phase 3 Study Of Romosozumab Compared With Teriparatide 9Emerus Announces Significant Strategic Investment By Welsh, Carson, Anderson & Stowe 2Emerus Announces Significant Strategic Investment By Welsh, Carson, Anderson & Stowe 3
    ... /PRNewswire-Asia-FirstCall/ -- Dehaier Medical Systems Ltd. (NASDAQ: ... emerging leader in the development, assembly, marketing and sale ... that the Company,s growing business earned a BBB+ Credit Rating ... "Zhongguancun Association") and was approved as a member of ...
    ... SHANGHAI, Feb. 28, 2012 /PRNewswire-Asia/ -- ShangPharma Corporation (NYSE: ... China-based pharmaceutical and biotechnology research and development outsourcing company, ... results for the fourth quarter and full year ended ... host a conference call to discuss the results at ...
    Cached Medicine Technology:Dehaier Medical Awarded Strong Credit Rating From Beijing Zhongguancun Enterprises Credit Promotion Association 2Dehaier Medical Awarded Strong Credit Rating From Beijing Zhongguancun Enterprises Credit Promotion Association 3ShangPharma to Report Fourth Quarter and Full Year 2011 Financial Results on March 13, 2012 2
    ... The SeedVac™ is a vacuum driven device designed to ... tube tip. Seeds are drawn into the clear tube ... the hand piece to create the vacuum. The prescribed ... the clear tube tip before being placed into the ...
    MT-BT-5001-25 prostate seeding needle (set of 25 unloaded needles).,MT-BT-5001-P prostate seeding needle, pre-plugged and pre-sterilized, unloaded or for use with MEDTECs ASAP™ pre-load seeding...
    ... a myoma was performed with a cutting ... vaporization of myomas with the VaporTrode Vaporization ... tissue chips that obscure visibility. No tissue ... This unique design provides areas of high ...
    ... The 19 Fr. OES 4000 Nephroscope, with ... quality with outstanding durability. The lumbotome, for ... the telescopic bougies, allow safer access. The ... comprehensive range of grasping forceps and lithotripsy ...
    Medicine Products: