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Orphan Drugs in Oncology Drug Pipeline Update 2013
Date:11/19/2013

membrane
-Nucleolus
-Nucleus
-Perinuclear region
-Perinuclear vesicle
-Plasma membrane
-Sarcoplasmic reticulum
-Secreted
-Secretory granule
-Secretory vesicle

Note: You are able to find and sort drugs according to target gene name, protein name, molecular function of target, target localization, presence of mutations and availability of biological structures of target from drop-down menus in the application.

Target Expression Profile
Direct links are provided from inside the application to 387 protein expression profiles of 248 drug targets in various human tissues and cancer types, cell lines and primary cells, including up to:
-48 different normal tissue types
-20 different types of cancer
-47 cell lines
-12 samples of primary blood cells

Pathway Referals
Identified targets have been cross referenced against their involvement in different cellular pathways, according to BioCarta, KEGG, NCI-Nature and NetPath.
-BioCarta# 245 Pathways
-KEGG# 190 Pathways
-NCI-Nature# 244 Pathways
-NetPath# 32 Pathways

Note: You are able to find and sort drugs according to targeted pathways from drop-down menus in the application.

Mechanism
In total there are different drug mechanism of action represented in this Drug Pipeline Update.

Note: You are able to find and sort drugs according to mechanism of action from drop-down menu in the application.

Compound
Identified drug compounds are described by:

Compound type, Chemical name, CAS Number and molecular weight

Note: You are able to sort and find drugs according to compound type from drop-down menu in the application.

Drug Profile
Progress analysis and review of drug development. A typical drug profile reports on, depending on stage of development and available information:

Drug Name & Synony
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