Navigation Links
Orlando Regional Medical Center (ORMC) Implements PNA FISH(R) Tests to Help Provide Better Care for Patients with Bloodstream Infections

WOBURN, Mass. and DURHAM, N.C., July 21 /PRNewswire/ -- AdvanDx and bioMerieux, Inc. today announced Orlando Regional Medical Center (ORMC), which is part of Orlando Health, has implemented the PNA FISH(R) tests from AdvanDx to identify bloodstream pathogens 1 to 2 days earlier to help their physicians, pharmacists and nurses improve care and outcomes for patients with bloodstream infections.

Every year, 350,000 patients contract bloodstream infections in the United States causing over 90,000 deaths and significant costs to the healthcare system. Rapid and accurate identification of the causative pathogen is crucial to ensuring appropriate antibiotic therapy and improving patient outcomes in this critical situation. Conventional diagnostic methods can take 48 hours or longer forcing physicians to treat patients empirically with broad-spectrum antibiotics that may prove to be ineffective or unnecessary and can lead to long-term resistance and mortality.

AdvanDx's PNA FISH tests employ unique technology that detects bacteria's genetic material to provide identification results in just over 2 hours. "The fast tests have enabled the microbiology lab to provide results 1 to 2 days sooner for such serious pathogens as Staphylococcus aureus, other staphylococci, Candida albicans and Candida glabrata," said Valerie Hoover, Microbiology Supervisor at ORMC.

Clinical trials conducted at hospitals in the United States have shown that implementing PNA FISH and delivering fast results to clinicians directed earlier, effective antibiotic therapy, reduced mortality rates and improved hospital operational efficiency by reducing hospital length of stay, bed utilization, and pharmacy and lab costs related to unnecessary antibiotic use. (1,2,3)

"We are excited about this latest diagnostic tool and we are already seeing improvements in how physicians treat patients based on this critical information being available sooner," said Mark Wallace, M.D., infectious disease physician at ORMC, who along with Andrew DeRyke, Pharm.D., Clinical Infectious Diseases Pharmacist, are championing the clinical implementation of using rapid microbiology results to guide therapy. "When the test tells us we dealing with a skin contaminant that is not causing infection, physicians are taking patients off unnecessary antibiotic. In addition, the faster identification for yeast pathogens is helping physicians prescribe the most effective antifungal drugs earlier for patients with Candidemia," Dr. Wallace added.

About Orlando Regional Medical Center

Orlando Health's flagship medical center, ORMC, is a tertiary care center with 808 acute care beds and is recognized as having one of Florida's largest cardiac programs.

ORMC is home to Central Florida's only Level One Trauma Center, which is one of only six in the state. It is Florida's first Level One Trauma Center to have an accredited Chest Pain Center and is supported by Central Florida's only hospital-based emergency air rescue transport service.

One of the state's six major teaching hospitals, ORMC offers graduate medical education in several specialties, including emergency medicine, OB/GYN, orthopedics, pediatrics and general surgery. Fellowship programs include colon rectal surgery, critical care surgery, pediatric orthopedics and hematology/oncology.

Additionally, ORMC provides sophisticated diagnostic and laboratory testing, medical and surgical services, intensive and progressive care, and wound management. ORMC also operates one of the state's regional burn and tissue rehabilitation centers.

For more information, visit


PNA FISH is an easy-to-use and highly sensitive and specific fluorescence in situ hybridization (FISH) assay that uses PNA (peptide nucleic acid) probes to target species specific ribosomal RNA (rRNA) in live bacteria and yeast. PNA FISH tests enable microbiology labs to provide rapid and accurate identification of bloodstream pathogens, including S. aureus, Enterococcus species, P. aeruginosa and Candida species, directly from positive blood cultures in hours instead of days. Clinical studies show that rapid identification of bloodstream pathogens using PNA FISH tests leads to more appropriate patient therapy that saves lives and reduces unnecessary antibiotic use, patient length of stay and hospital costs.

For more information, visit


1. Forrest et al. Antimicrob Agents Chemother. 2008 Oct;52(10):3558-63.

2. Shoham et al. Ther Clin Risk Manag. 2008 Jun;4(3):637-40.

3. Forrest et al. J Antimicrob Chemother. 2006 Jul;58(1):154-8.

Copyright©2009 PR Newswire.
All rights reserved

Related medicine news :

1. United Spinal Associations 2009 Independence Expo Aug 7th-8th in Orlando: Improving Life for the Disabled and the Aging
2. United Spinal Associations 2009 Independence Expo Aug. 7th-8th In Orlando: Improving Life for the Disabled and the Aging
3. Orlando Dermatology Aesthetic & Clinical (ODAC) Conference Announces Its 2010 Event
4. Sisters of Charity Health System Appoints Orlando L. Alvarez Jr. to Head Physician Strategy and Business Development
5. National Eyewear Chain Visionworks Opens Two New Stores in Orlando Market
6. New Family Dental Practice Opens in Orlando
7. Herzing College, Orlando Will Change Name to Herzing University and Host Sign-Changing Event on March 2, 2009
8. Optelec and Bring Life Back Into Focus at ATIA 2009 Orlando
9. Grossology Exhibit Captivates Kids at The Orlando Science Center
10. FFF Enterprises Unveils ‘The 8 Critical Steps to Guaranteed Channel Integrity' at the American Society of Health-System Pharmacists (ASHP) Midyear Meeting in Orlando
11. Medical Spa Consulting from Best Medspa in America to Provide Advanced Medical Spa Education at Medspa Conference in Orlando, FL
Post Your Comments:
(Date:11/25/2015)... ... 2015 , ... TyloHelo Inc , North America’s largest ... accessories help improve the bather experience in the sauna, and the accessories selected ... purist looking for simplicity in design to accessories that encourage a greater expression ...
(Date:11/25/2015)... , ... November 25, 2015 , ... For the first ... “ Two Organizations, One Beat ” campaign. The partnership between the two groups began ... aid in MAP International’s cause. , MAP International was founded in 1954 and is ...
(Date:11/25/2015)... ... November 25, 2015 , ... On November 25, 2015, ... for the Narconon network, announced the release of a new cutting edge recovery program ... organization has been working with drug- and alcohol-addicted individuals with the purpose to free ...
(Date:11/25/2015)... , ... November 25, 2015 , ... Smiles by ... TMJ Disorder, Bruxism, and moderate facial wrinkling. While many patients are aware of the ... the great success Botox® delivers to those suffering with discomfort, soreness, and pain as ...
(Date:11/25/2015)... ... ... In an ongoing Clinical Study conducted by an independent physician, Andrew Gostine, ... evaluating the efficacy of its product and its disinfection protocol. This study is taking ... 2014 through October 2015 at a 360-bed, acute-care, academic medical center located in Chicago, ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... , Nov. 25, 2015 USP ... hazardous drug preparations (e.g. pharmacists, pharmacy technicians, nurses, ... veterinary technicians). The chapter also covers all entities ... (e.g., pharmacies, hospitals, other healthcare institutions, patient treatment ... --> --> What ...
(Date:11/25/2015)... 25, 2015 Asia ... which BioLight and the New Investors will make a ... via a private placement. The financing will help IOPtima ... system used in the treatment of glaucoma, as well ... the IOPtimate™ system with the U.S. Food and Drug ...
(Date:11/25/2015)... LONDON , November 25, 2015 Developmental, ... key role in boosting the profitability of pharmaceutical products, ... Developmental, commercial, and regulatory/legal strategies all play ... says GBI Research . --> ... all play a key role in boosting the profitability of pharmaceutical ...
Breaking Medicine Technology: