Navigation Links
Origin of aggressive ovarian cancer discovered
Date:3/6/2013

marker for stem cells, called ALDH1. They then isolated ALDH1 positive cells, sequenced their genetic profiles and found many markers previously reported for stem cells in other organs.

One of these markers, LGR5, has been studied for intestinal stem cells by other researchers who have bred special mice and developed an advanced method that uses a fluorescent protein to follow stem cells. The gene encoding the fluorescent protein is passed down from a stem cell to each generation of daughter cells, thereby marking the lineage. The technique "allows you to see the fate of stem cells over time," said Nikitin. Using the method on the hilum cells, "we showed that cells from the hilum area spread around the whole ovary."

Finally, the researchers microdissected ovary and hilum cells, inactivated two tumor suppressor genes p53 and Rb1, whose pathways are commonly altered in human aggressive ovarian carcinoma, and injected cells into the abdominal cavity of mice. Very few tumors developed in the mice injected with ovary cells, but almost all of the mice injected with hilum cells died after developing aggressive, metastasizing cancers that were similar to human ovarian carcinomas.

In future work, the researchers will look for stem cells and sources of cancer in transitional zones in the human ovary and other organs, such as the stomach, rectum and uterine cervix.


'/>"/>

Contact: Joe Schwartz
bjs54@cornell.edu
607-254-6235
Cornell University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Bel Marra Health Reports on a New Study: Software Originally Used for Star Gazing Now Being Used to Analyze Breast Cancer Tissue
2. Serious Collector Announces His Search for Original Jimi Hendrix 1968 Independence Hall Baton Rouge, Louisiana Concert Poster
3. EvolutionHealth.com Introduces the the Original Bodylift Yoga Headstand as Used by Martha Stewart, Reverse the Negative Effects of Gravity on the Body
4. Originals By Weber's New Invention: "EZoo" Denture Liner Is Eazy To Put On/Eazy To Take Off Makes Loose Dentures Fit Better
5. Tracking the origins of HIV
6. Massage and the Aboriginal Didgeridoo - A Transcendental Healing Experience in the Heart of New York City
7. Study finds reformulated ER Oxycodone abuse rates are significantly lower than original ER Oxycodone
8. For brain tumors, origins matter
9. Jamaican teen immigrants do better when they retain strong ties to original culture
10. The ORIGIN-GRACE study
11. Stimulant marketed as natural in sports supplement actually of synthetic origin
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/25/2014)... TASC (Total Administrative Services Corporation), ... account management services, announces the release of four ... taxes, reduce administrative workload, and lessen liability. ... the efficient handling of complex, time-sensitive, and labor-consuming ... meets their goals and objectives. The four Suites ...
(Date:10/25/2014)... 2014 QueenBeeTickets.com has a variety of ... at affordable prices. Bob Seger & The Silver Bullet ... Nationwide Arena are going on sale October 25 and ... to browse the selection of tickets for Bob ... The famous singer is touring North America beginning next ...
(Date:10/25/2014)... October 25, 2014 Mesothelioma researchers are ... to receive pemetrexed (Alimta), after his combination drug therapy ... full story , just posted on the Surviving Mesothelioma ... Tokushukai Medical Center in Japan suggests that “maintenance therapy” ... patients who cannot tolerate higher doses of cisplatin. ...
(Date:10/25/2014)... Reinberg HealthDay Reporter FRIDAY, ... common cold sores -- herpes simplex -- might increase the ... In fact, being a carrier of certain antibodies to ... researchers found. "The identification of a treatable cause ... breakthrough," said lead researcher Dr. Hugo Lovheim, an associate professor ...
(Date:10/25/2014)... News) -- A large influx of international aid is ... tens of thousands of deaths from the widening Ebola ... Using a specially designed mathematical model, the researchers ... just one densely populated county of hard-hit Liberia -- ... The researchers said that if international aid isn,t ...
Breaking Medicine News(10 mins):Health News:TASC’s New Suites Offer Tax Savings and Protection 2Health News:QueenBeeTickets.com Features Bob Seger & The Silver Bullet Band Tickets for Charleston Civic Center, Huntington Center, and Nationwide Arena at Reduced Prices 2Health News:New Report Illustrates Extended Mesothelioma Survival with “Maintenance Therapy”, According to Surviving Mesothelioma 2Health News:Studies Link Cold Sore Virus to Alzheimer's Risk 2Health News:Studies Link Cold Sore Virus to Alzheimer's Risk 3Health News:Experts Predict 'Catastrophic' Ebola Epidemic in West Africa if Aid Delayed 2
... and television that anger causes// the cardiac arrest of ... Yale University researchers have found out that sudden strong ... in the heart to twitch. This may be especially ... although seemingly healthy people my also be affected. ...
... Surrey, UK, had developed a new// drug that will boost ... is made of a compound called CX717, and it is ... This drug had showed effectiveness in increasing memeory, alertness, increasing ... who sleep less. ,The drug was given to ...
... had successfully created a new breed of mice that can ... for themselves.//, ,The reactive oxygen of the free radicals ... to poor health and even death. The new research may ... radical theory of ageing. ,The new mice created ...
... may lead to babies born with deformed prostate glands.//, ... out that prostate deformities can happen if the pregnant ... The pills contain ostrogen like chemiclasthat are alos present ... can cause prostate cancer or bladder diseases later in ...
... study that looked into the smoking habit of 6654 people ... that giving up smoking do causes weight gain, but the ... population under study was measured for effect of giving up ... when the age group was 20 to 44yrs, and was ...
... levels of blood marker for inflammation that can //lead to ... say that it may be good for the health of ... man will have a close family, a good group of ... the workplace, or the neighbors, or a religious organization. ...
Cached Medicine News:
(Date:10/22/2014)... , Oct. 22, 2014  Medical ... laboratory which specializes in high complexity, state-of-the-art, ... is now offering new Cystic Fibrosis Testing ... generation DNA sequencing platforms. Cystic ... inherited multisystem disorder that affects the respiratory, ...
(Date:10/22/2014)... FAIRFIELD, N.J. , Oct. 22, 2014 /PRNewswire/ ... a major transformation in the pain market, according ... Pain Insights, Inc., a firm providing market research ... management. Photo - http://photos.prnewswire.com/prnh/20141021/153440 ... a scheduling change for hydrocodone combination products from ...
(Date:10/22/2014)... October 22, 2014 Investor-Edge has ... (NASDAQ: FOLD ), Progenics Pharmaceuticals Inc. (NASDAQ: ... THLD ), Idera Pharmaceuticals Inc. (NASDAQ: ... research on these five companies can be accessed at: ... 2014, the NASDAQ Composite ended at 4,419.48, up 2.40%, ...
Breaking Medicine Technology:Medical Diagnostic Laboratories, L.L.C. Institute for Biomarker Research Announces New Prenatal Cystic Fibrosis Tests 2Hydrocodone: Rescheduled, Repositioned & Reinvented 2Hydrocodone: Rescheduled, Repositioned & Reinvented 3Market Momentum on Biotech Stocks - Amicus Therapeutics, Progenics Pharma, Threshold Pharma, Idera Pharma, and Merrimack Pharma 2Market Momentum on Biotech Stocks - Amicus Therapeutics, Progenics Pharma, Threshold Pharma, Idera Pharma, and Merrimack Pharma 3Market Momentum on Biotech Stocks - Amicus Therapeutics, Progenics Pharma, Threshold Pharma, Idera Pharma, and Merrimack Pharma 4Market Momentum on Biotech Stocks - Amicus Therapeutics, Progenics Pharma, Threshold Pharma, Idera Pharma, and Merrimack Pharma 5
... and VANCOUVER, April 26, 2007,/PRNewswire-FirstCall/ - Angiotech ... medical device company, announced that,the two-year data ... Wrap(TM) Paclitaxel-Eluting Mesh ("Vascular Wrap(TM)"),will be presented ... The,two-year study examined the safety and efficacy ...
... 26, 2007 - A new study published ... ("A National Survey of,Physician-Industry Relationships") on the ... the need for,profession-wide and public policy reforms ... that the existing,voluntary PhRMA (Pharmaceutical Research and ...
Cached Medicine Technology:Two-year data for Angiotech's Vascular Wrap Paclitaxel-Eluting Mesh,to be Presented at European Vascular Symposium 2Two-year data for Angiotech's Vascular Wrap Paclitaxel-Eluting Mesh,to be Presented at European Vascular Symposium 3Two-year data for Angiotech's Vascular Wrap Paclitaxel-Eluting Mesh,to be Presented at European Vascular Symposium 4Two-year data for Angiotech's Vascular Wrap Paclitaxel-Eluting Mesh,to be Presented at European Vascular Symposium 5Two-year data for Angiotech's Vascular Wrap Paclitaxel-Eluting Mesh,to be Presented at European Vascular Symposium 6Two-year data for Angiotech's Vascular Wrap Paclitaxel-Eluting Mesh,to be Presented at European Vascular Symposium 7Ties Between Physicians and Drug Companies Still Too Strong: the,Prescription Project Offers Solutions to Prevent Conflicts of,Interest 2
MDI will work with your facility to determine the best interim lab to fit your needs and your site....
... layout is designed efficiently for maximum ... configured for maximum efficiency. It is ... It can be set-up in 15 ... mobile modality pad and it has ...
... is the largest and most experienced provider ... in the United States. Mobile laboratories serving ... daily basis, from one hospital to another ... area. Each mobile laboratory is fully equipped ...
... PowerSuite holmium laser combines excellent cutting, ... virtually bloodless procedures. It is also ... gall bladder stones of all compositions, ... tool. Because its laser light is ...
Medicine Products: