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Orange County research program aims to improve severe trauma survival rates
Date:7/8/2008

Irvine, Calif., July 8, 2008 A method of resuscitation for victims of severe traumatic injury will be the subject of a clinical trial to be undertaken by a team of Orange County emergency care providers.

The Orange County Resuscitation Outcomes Consortium will include UC Irvine, Orange County Health Care Agency, Mission Hospital, Western Medical Center Santa Ana, Orange County Fire Authority, and fire departments from other Orange County cities.

The ROC group will conduct and oversee a clinical effort in which people who receive severe traumatic injury such as in a serious motor vehicle accident will be treated with hypertonic saline solution as part of the emergency medical response. Previous studies have shown that hypertonic saline safely and effectively decreases inflammation, especially with brain trauma, and that survival outcomes potentially can improve.

Orange County ROC is part of a National Institutes of Health federally funded study involving emergency medical services agencies, public safety agencies, regional hospitals, community healthcare institutions and medical centers in 11 regions in the United States and Canada, and as many as 15,000 patients over a three-year period. The overall goal is to learn the best ways to improve survival from cardiac arrest and severe trauma. Orange County will participate only in the trauma portion of the study.

"Clinical research has made great advances in medical care over the past quarter century, but there have been few similar advances in the area of emergency response care. The ROC study represents the greatest effort yet to make advances in this area and help save the lives of the thousands of Americans each year who otherwise would die from their traumatic injuries," said Dr. David Hoyt, the John E. Connolly, M.D., Chair of Surgery at UC Irvine Medical Center and Orange County ROC study leader. Hoyt, one of the nation's top trauma surgeons, leads the ROC trauma
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Contact: Tom Vasich
tmvasich@uci.edu
949-824-6455
University of California - Irvine
Source:Eurekalert

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