Navigation Links
Oral osteoporosis meds appear to reduce the risk of jaw degradation
Date:1/2/2008

BOSTON, Mass. (Jan. 2, 2008) Athanasios Zavras began receiving messages from distraught patients in 2005 after case reports linked oral osteoporosis meds to bone death in the jaw. A number of doctors and dentists advised women and men taking these drugs to postpone dental work, fearing that procedures such as tooth extractions would exacerbate the problem. Thats when Zavras, an associate professor in the Harvard School of Dental Medicine, decided to take a closer look at the purported link.

After analyzing the medical claims of 714,217 people, Zavras, along with Vassiliki Cartsos at the Tufts University School of Dental Medicine and Shao Zhu of Ingenixi3 Drug Safety (the company that provided medical claims data), have concluded that oral osteoporosis meds seem to reduce the risk of jaw degradation. Clinical studies are needed to replicate and clarify the results, which appear in the January issue of the Journal of the American Dental Association.

This is good news for the roughly 3 million Americans who take Fosamax, Actonel, Boniva or similar osteoporosis meds orally, says Zavras, who is also director of dental public health in the Department of Oral Health Policy and Epidemiology.

The drugs, which are called bisphosphonates, inhibit cells that break down bone tissue, and a growing number of Americans with osteoporosis or low bone mass ingest them orally to halt bone loss. In fact, they have been used for this purpose since 1977. Some cancer patients also rely on bisphosphonates to prevent bone fragility and metastasis, but these individuals typically receive potent intravenous versions of the drugs.

In 2003, case reports linked the potent versions to bone death in the jaw, and subsequent studies confirmed the statistical significance of the association. Concern was limited to intravenous bisphosphonates until May 2005, when the Journal of Oral and Maxillofacial Surgery published a report on 63 patients with bone death in
'/>"/>

Contact: Alyssa Kneller
public_affairs@hms.harvard.edu
617-432-0442
Harvard Medical School
Source:Eurekalert

Page: 1 2

Related medicine news :

1. National Osteoporosis Foundation Teams Up With Ladies Home Journal Magazine to Launch a 10-city Mall Walk Tour
2. FDA Approves Osteoporosis Drug to Cut Breast Cancer Risk
3. Weekly dose of osteoporosis drug prevents bone loss after breast cancer treatment
4. Plenary lectures announced for worlds largest osteoporosis congress
5. Story Reveals How Isabel and Her Family Learn About Bone Health and Osteoporosis
6. Video: Kyphon Supports World Osteoporosis Day on October 20, 2007 to Raise Awareness of Osteoporosis and Spinal Fracture Risk
7. Kaiser Permanente study shows electronic medical records and outreach improve osteoporosis care
8. Bad to the bone: UD research to shed light on osteoporosis
9. Geisinger rheumatologists redesign osteoporosis, rheumatoid arthritis care
10. Proposed Bill to Protect Patient Access to Osteoporosis Testing by Reversing Cuts in Medicare Reimbursement
11. High-trauma fractures in older men and women linked to osteoporosis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/13/2014)... 13, 2014 A decreased ability to identify ... and Alzheimer,s disease, while examinations of the eye ... associated with Alzheimer,s, in the brain, according to ... at the Alzheimer,s Association International Conference 2014 (AAIC ... studies, the decreased ability to identify odors was ...
(Date:7/13/2014)... WA (PRWEB) July 13, 2014 ... Woolcott, who commented, “As a parent of a special ... underserved need in the Seattle community for contemporary special ... provide an important alternative to students and families in ... best practices and environment for special education. We welcome ...
(Date:7/13/2014)... Recently, iFitDress.com, one of the most ... outfits, has added a new selection of beautiful ... has launched a promotion for these evening gowns. Now, ... is now providing thousands of graceful gowns in its ... Britain, America, France, Italy and many other countries. They ...
(Date:7/12/2014)... The Passenger Information System market is estimated to ... by 2019, at an expected CAGR of 26.5% for ... transport infrastructure in North America is well developed and ... corner of the region. The growing ridership figures in ... providers are driving the North American Passenger Information System ...
(Date:7/12/2014)... July 12, 2014 ... Peripheral Vascular Devices Market by Angioplasty ... Catheter (IVUS, OCT), IVC Filter (Retrievable), ... 2018" analyzes and studies the major ... the U.S. and Canada. , Browse ...
Breaking Medicine News(10 mins):Health News:Smell and eye tests show potential to detect Alzheimer's early 2Health News:Smell and eye tests show potential to detect Alzheimer's early 3Health News:Smell and eye tests show potential to detect Alzheimer's early 4Health News:Smell and eye tests show potential to detect Alzheimer's early 5Health News:Smell and eye tests show potential to detect Alzheimer's early 6Health News:Smell and eye tests show potential to detect Alzheimer's early 7Health News:New Private School, Emerald City School, Founded in Downtown Seattle Now Accepting 1st to 6th Grade Students Who Learn Differently 2Health News:New and Beautiful Evening Dresses Unveiled by iFitDress.com 2Health News:North America Passenger Information System (ICT) Market worth $5,486.88 Million by 2019 - New Report by MicroMarket Monitor 2Health News:North America Passenger Information System (ICT) Market worth $5,486.88 Million by 2019 - New Report by MicroMarket Monitor 3Health News:North America Passenger Information System (ICT) Market worth $5,486.88 Million by 2019 - New Report by MicroMarket Monitor 4Health News:North American Interventional Cardiology & Peripheral Vascular Devices Market - New Report by MarketsandMarkets 2Health News:North American Interventional Cardiology & Peripheral Vascular Devices Market - New Report by MarketsandMarkets 3Health News:North American Interventional Cardiology & Peripheral Vascular Devices Market - New Report by MarketsandMarkets 4Health News:North American Interventional Cardiology & Peripheral Vascular Devices Market - New Report by MarketsandMarkets 5
... overweight and obese people getting? More than many ... Case Western Reserve University,s Frances Payne Bolton School of ... Journal of the American Academy of Nurse Practitioners ... individuals." Deborah Walton Smith, who is now a ...
... failure who repress their emotions, especially anger, are more ... depression associated with knowledge about their disease, according to ... study influenced how depressed or anxious they felt. The ... more likely they were to have symptoms of depression ...
... Not a single person identified with autism or asperger,s ... they had the condition, research led by the University ... Professor of Psychiatry at the University of Leicester, the ... males, those without higher educational qualifications, and those living ...
... Children,s health problems caused by air pollution, exposure to toxic ... billion in 2008, a new study finds. That was ... compared with 2.8 percent in 1997, said researchers from the ... the cost of childhood cancer and chronic conditions such as ...
... studies have shown that a 64-detector CT angiography ... image but considerably reduced patient radiation dose when ... being presented at the 2011 American Roentgen Ray ... in the Department of Radiology at the University ...
... HealthDay Reporter , TUESDAY, May 3 (HealthDay News) -- The ... more than 12 percent between 2001 and 2009, U.S. health ... people, according to the U.S. Centers for Disease Control and ... million Americans have asthma "and that number, unfortunately, is rising," ...
Cached Medicine News:Health News:Making the move to exercise for overweight and obese people 2Health News:More knowledge not always helpful for women dealing with heart disease 2Health News:More knowledge not always helpful for women dealing with heart disease 3Health News:More knowledge not always helpful for women dealing with heart disease 4Health News:'Most adults with autism go undiagnosed' -- new findings 2Health News:'Most adults with autism go undiagnosed' -- new findings 3Health News:Treating Kids for Environmental Ills Costs U.S. $76B a Year 2Health News:Low-dose chest CT effective in reducing radiation for evaluation of cardiothoracic surgery patients 2Health News:Number of Americans With Asthma Keeps Rising 2Health News:Number of Americans With Asthma Keeps Rising 3
(Date:7/10/2014)... -- Valeant Pharmaceuticals International, Inc. (NYSE: VRX ... sale to Galderma of all rights to Restylane, Perlane, ... for $1.4 billion in cash, pursuant to the previously ... acquisition of Galderma. "We are pleased ... company that is firmly committed to the aesthetic dermatology ...
(Date:7/10/2014)... Decision Resources Group finds that over half ... and Drug Administration,s (FDA) approval of Vifor Fresenius Medical ... approved by the FDA in November 2013 for the ... on dialysis. Other key findings from the ... : , Bundling: ...
(Date:1/15/2014)... Jan. 15, 2014 As health officials across the Midwest ... Meijer pharmacies in Michigan will offer ... patients, enabling Meijer pharmacists to administer tests and, in some ... a physician participating in the study. The ...
Breaking Medicine Technology:Half of Surveyed Nephrologists Report Moderate Familiarity with Velphoro, Which Received FDA Approval Late Last Year for the Treatment of Hyperphosphatemia in Dialysis 2Half of Surveyed Nephrologists Report Moderate Familiarity with Velphoro, Which Received FDA Approval Late Last Year for the Treatment of Hyperphosphatemia in Dialysis 3Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 2Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 3
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: