Navigation Links
Oral drug may improve survival in men with metastatic prostate cancer
Date:11/19/2013

DURHAM, N.C. An investigational prostate cancer treatment slows the disease's progression and may increase survival, especially among men whose cancer has spread to the bones, according an analysis led by the Duke Cancer Institute.

The study, published on Nov. 19, 2013, in the journal Clinical Cancer Research, adds long-term survival and safety data for the drug tasquinimod, a new candidate for treating advanced and recurrent prostate cancer.

"While all subgroups in the clinical trial benefited from tasquinimod, those whose cancer metastasized to their bones had the greatest benefit in terms of delaying the time from the start of treatment to when the cancer progressed," said lead author Andrew J. Armstrong, M.D., ScM, associate professor of medicine at the Duke Cancer Institute. "This group of men also seemed to have a longer survival benefit when we followed them over several years."

Tasquinimod, a drug in development by Active Biotech in partnership with Ipsen, is an oral therapy that activates the body's immune system to fight cancer. Its mechanism is not fully understood, but it appears to affect the function of myeloid-derived suppressor cells, which are found in increased numbers in cancer patients. Tasquinimod is also known to block tumor blood vessel growth, a process termed angiogenesis.

New treatments approved in recent years have given physicians and patients additional options to fight prostate cancer, but the therapies typically only extend patients' lives by three to five months. New drugs that increase survival without serious side effects are still needed.

In this phase II clinical trial, funded by Active Biotech, researchers studied the use of tasquinimod among men with metastatic castration-resistant prostate cancer, an advanced form of the disease that does not respond to hormonal therapy. The study enrolled 201 men who were followed for approximately three years, with 134 randomly assi
'/>"/>

Contact: Rachel Harrison
rachel.harrison@duke.edu
919-419-5069
Duke University Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Clinical insight improves treatment with new lung cancer drug
2. Improved Stem Cell Line May Avoid Tumor Risk: Study
3. Normalizing tumor blood vessels improves delivery of only the smallest nanomedicines
4. Exercise improves quality of life during breast cancer treatment
5. IU, Regenstrief automated system aims to improve child health
6. Swallowing exercises linked with short-term improvement among patients with head and neck cancer
7. MU receives national award for using mind-body approach to improve health
8. Feelings of immaturity accompany alcohol misuse into adulthood; discovery could improve treatments
9. Awards celebrate clinical research that can improve health and alleviate suffering
10. Naturopathic care can improve blood sugar, mood in diabetes
11. Early treatment improves outcomes in rare, often undiagnosed form of encephalitis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/26/2014)... Los Angeles, CA (PRWEB) December 26, 2014 ... buyer power score of 3.1 out of 5. This ... from a low level of product specialization, low switching ... buyer power is reduced by the low availability of ... in the world price of steel and aluminum, key ...
(Date:12/26/2014)... WA (PRWEB) December 26, 2014 “Many ... deal with personal injury claim issues and phone calls ... recently released an article featuring their free eBook ... exceptionally helpful eBook on pedestrian and bicycle auto accident ... attorney is fully capable of professionally handling their case ...
(Date:12/26/2014)... AZ (PRWEB) December 26, 2014 ... source for the best in heating, cooling and ... for 24 hour emergency services in 2014 with ... alike know that Arizona is known for its ... company that understands the intricacies and details of ...
(Date:12/25/2014)... 26, 2014 The report “Nintedanib ... 2023” focuses on the current treatment landscape, unmet ... colorectal cancer market. Stivarga is a drug which ... rectal cancer. Boehringer Ingelheim is developing nintedanib (BIBF-1120), ... of refractory CRC in the US, Europe, and ...
(Date:12/25/2014)... Recently, iFitDress.com, the popular online supplier of wedding dresses and ... of black one-shoulder cocktail dresses . In addition, all ... at discounted prices, up to 70% off. , ... weeks only. You know, we have thousands of frequent callers ... new items can visit our website for more details. The ...
Breaking Medicine News(10 mins):Health News:Cooking & Warming Equipment Procurement Category Market Research Report from IBISWorld has Been Updated 2Health News:Cooking & Warming Equipment Procurement Category Market Research Report from IBISWorld has Been Updated 3Health News:Guide to Handling Pedestrian and Bicycle Accidents Released By The Jones Firm, Featured in Recent Article 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 3Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 2Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 3Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 4Health News:iFitDress.com: Black One-Shoulder Cocktail Dresses for 2015 2
... of strategic workforce management consulting and implementation services, announced the ... the firm,s growing base of healthcare clients striving to more effectively ... management solutions. , ... Denver, CO (PRWEB) April 1, ...
... El Cigarrillo Electronico Más Pequeño del Mundo se ha introducido ... de fumar de millones de fumadores en todo el mundo. ... ... Alicante -- Los fumadores son adictos a la nicotina que ...
... more than any hospital in the U.S. , ... Evanston, IL (Vocus) ... one of the nation,s 100 Top Hospitals® by Thomson Reuters, a leading ... healthcare. NorthShore has been named a Top 100 Hospital thirteen times, more ...
... Researchers have identified a possible genetic cause for ... colorectal cancer in blacks that leads to shorter ... Cancer Research , a journal of the American ... relationship between molecular defects and differences in colorectal ...
... Limited Resources Create Missed Opportunities for Smokers to Quit ... one of the most important allies a smoker can ... of smoking and learning about the quitting process. Why, ... never talked to a HCP about their ...
... Calif., March 31 iVisit, LLC announced ... as a finalist in the Fourth Annual CTIA Emerging ... Healthcare category.The E-Tech Awards ceremony takes place Thursday, April ... in South Hall. The program is designed to give ...
Cached Medicine News:Health News:Director of Healthcare Solutions Appointed to Guide Workforce Management Initiatives for Hospitals and Long Term Care Facilities 2Health News:Director of Healthcare Solutions Appointed to Guide Workforce Management Initiatives for Hospitals and Long Term Care Facilities 3Health News:Cigarrillo Electronico "Excelente 2009" Introducido por MiCigarrillo™ 2Health News:Cigarrillo Electronico "Excelente 2009" Introducido por MiCigarrillo™ 3Health News:NorthShore University HealthSystem Named One of the Nation's Top 100 Hospitals by Thomson Reuters 2Health News:NorthShore University HealthSystem Named One of the Nation's Top 100 Hospitals by Thomson Reuters 3Health News:Not Enough Smokers Find Quit Support at the Doctor's Office 2Health News:Not Enough Smokers Find Quit Support at the Doctor's Office 3Health News:Not Enough Smokers Find Quit Support at the Doctor's Office 4Health News:iVisit Named Finalist in CTIA Wireless 2009(R) CTIA E-Tech Awards for Innovation in Enterprise & Vertical - Healthcare Solution 2Health News:iVisit Named Finalist in CTIA Wireless 2009(R) CTIA E-Tech Awards for Innovation in Enterprise & Vertical - Healthcare Solution 3
(Date:12/22/2014)... Pa. and STOCKHOLM , ... (publ) (Sobi) and partner Auxilium Pharmaceuticals, Inc. today announced ... (CHMP) of the European Medicines Agency (EMA) has adopted ... clostridium histolyticum) for the treatment of adult men with ... of at least 30 degrees at the start of ...
(Date:12/22/2014)... , Dec. 22, 2014  Mark Farrah Associates ... providing a summary of the 2015 marketplace exchange ... trends.  According to a recent ... and Evaluation, Department of Health and Human Services) ... in individual medical plans through the Marketplace as ...
(Date:12/22/2014)... Dec. 22, 2014  Pfenex Inc. (NYSE MKT: PFNX) ... vaccine, has been filed and is now open and ... the Department of Health and Human Services (HHS), through ... "We are extremely pleased to have the IND ... represents a significant milestone in our company,s partnership with ...
Breaking Medicine Technology:Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 2Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 3Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 4Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 5Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 6Insights into the Marketplace and Individual Market Growth 2Pfenex Announces Active IND and Additional BARDA Funding for Recombinant Anthrax Vaccine Program, Px563L 2Pfenex Announces Active IND and Additional BARDA Funding for Recombinant Anthrax Vaccine Program, Px563L 3
... announces that a new market research report is available ... Market Outlook to 2016 http://www.reportlinker.com/p0336614/Europe-Neurology-Devices-Market-Outlook-to-2016.html ... 2016 SummaryGlobalData,s new report, "Europe Neurology ... on the Europe Neurology Devices market – Germany, France, ...
... 8, 2010 Reportlinker.com announces that a ... its catalogue: Medical Polymers ... Dominating the Medical Devices and Packaging Markets ... Medical Polymers Market to 2015 ...
Cached Medicine Technology:Reportlinker Adds Europe Neurology Devices Market Outlook to 2016 2Reportlinker Adds Europe Neurology Devices Market Outlook to 2016 3Reportlinker Adds Europe Neurology Devices Market Outlook to 2016 4Reportlinker Adds Europe Neurology Devices Market Outlook to 2016 5Reportlinker Adds Europe Neurology Devices Market Outlook to 2016 6Reportlinker Adds Europe Neurology Devices Market Outlook to 2016 7Reportlinker Adds Europe Neurology Devices Market Outlook to 2016 8Reportlinker Adds Europe Neurology Devices Market Outlook to 2016 9Reportlinker Adds Europe Neurology Devices Market Outlook to 2016 10Reportlinker Adds Europe Neurology Devices Market Outlook to 2016 11Reportlinker Adds Europe Neurology Devices Market Outlook to 2016 12Reportlinker Adds Europe Neurology Devices Market Outlook to 2016 13Reportlinker Adds Europe Neurology Devices Market Outlook to 2016 14Reportlinker Adds Europe Neurology Devices Market Outlook to 2016 15Reportlinker Adds Medical Polymers Market to 2015 - Polyvinyl Chloride (PVC) Dominating the Medical Devices and Packaging Markets 2Reportlinker Adds Medical Polymers Market to 2015 - Polyvinyl Chloride (PVC) Dominating the Medical Devices and Packaging Markets 3Reportlinker Adds Medical Polymers Market to 2015 - Polyvinyl Chloride (PVC) Dominating the Medical Devices and Packaging Markets 4Reportlinker Adds Medical Polymers Market to 2015 - Polyvinyl Chloride (PVC) Dominating the Medical Devices and Packaging Markets 5Reportlinker Adds Medical Polymers Market to 2015 - Polyvinyl Chloride (PVC) Dominating the Medical Devices and Packaging Markets 6Reportlinker Adds Medical Polymers Market to 2015 - Polyvinyl Chloride (PVC) Dominating the Medical Devices and Packaging Markets 7Reportlinker Adds Medical Polymers Market to 2015 - Polyvinyl Chloride (PVC) Dominating the Medical Devices and Packaging Markets 8Reportlinker Adds Medical Polymers Market to 2015 - Polyvinyl Chloride (PVC) Dominating the Medical Devices and Packaging Markets 9Reportlinker Adds Medical Polymers Market to 2015 - Polyvinyl Chloride (PVC) Dominating the Medical Devices and Packaging Markets 10
Reliable and Affordable. The Schuco 3000 Nebulizer by Allied has been designed to offer a compact style that provides worry-free affordable nebulizer therapy....
... Graham-Field has been developing diverse ... 58 years. Our medical-surgical products ... for innovation, quality and customer ... include the Labtron® line of ...
... Nebulizers deliver particulate humidity in the 3 ... secretion patients. For your convenience, Thera-Mist® nebulizers ... of sterile water., ,The P30000N, for ... 20-50% with a total flow range of ...
... Hand Held Nebulizer can be held at angles ... has a built in spill column, finger grooves ... medication setups and 7 feet of regular oxygen ... maintain small particle size and sustain optimum mist ...
Medicine Products: