Navigation Links
Oral bacteria may signal pancreatic cancer risk
Date:9/18/2012

PROVIDENCE, R.I. [Brown University] A new study finds significant associations between antibodies for multiple oral bacteria and the risk of pancreatic cancer, adding support for the emerging idea that the ostensibly distant medical conditions are related.

The study of blood samples from more than 800 European adults, published online Sept. 18 in the journal Gut, found that high antibody levels for one of the more infectious periodontal bacterium strains of Porphyromonas gingivalis were associated with a two-fold risk for pancreatic cancer. Meanwhile, study subjects with high levels of antibodies for some kinds of harmless "commensal" oral bacteria were associated with a 45-percent lower risk of pancreatic cancer.

"The relative increase in risk from smoking is not much bigger than two," said Brown University epidemiologist Dominique Michaud, the paper's corresponding author. "If this is a real effect size of two, then potential impact of this finding is really significant."

Pancreatic cancer, which is difficult to detect and kills most patients within six months of diagnosis, is responsible for 40,000 deaths a year in the United States.

Several researchers, including Michaud, have found previous links between periodontal disease and pancreatic cancer. The Gut paper is the first study to test whether antibodies for oral bacteria are indicators of pancreatic cancer risk and the first study to associate the immune response to commensal bacteria with pancreatic cancer risk. The physiological mechanism linking oral bacteria and pancreatic cancer remains unknown, but the study strengthens the suggestion that there is one.

"This is not an established risk factor," said Michaud, who is also co-lead author with Jacques Izard, of the Forsyth Institute and Harvard University. "But I feel more confident that there is something going on. It's something we need to understand better."

Izard, a micro
'/>"/>

Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Discovery of essential genes for drug-resistant bacteria reveals new, high-value drug targets
2. Superpowered Bacteria May Lurk Behind Sinus Infections
3. Feces-Linked Bacteria Found at Lake Erie Beaches
4. Could Bacteria in Skin Mites Help Cause Rosacea?
5. New antibacterial coating for sutures could reduce infections after surgery
6. Trudeau researchers identify unforeseen regulation of the anti-bacterial immune response
7. Microbiology and Genome Experts Quell Deadly Bacteria Outbreak
8. NIH uses genome sequencing to help quell bacterial outbreak in Clinical Center
9. Genes carried by E. coli bacteria linked to colon cancer
10. Protective bacteria in the infant gut have resourceful way of helping babies break down breast milk
11. Chronic exposure to staph bacteria may be risk factor for lupus, Mayo study finds
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Oral bacteria may signal pancreatic cancer risk
(Date:9/23/2014)... PA (PRWEB) September 23, 2014 "The primary ... infection control," said an inventor from Sacramento, Ca.. "Call lights ... bedding or left hanging on the IV pole out of ... have the nurse call device whenever they need it, I ... to effectively position the nurse call device within easy reach. ...
(Date:9/23/2014)... From first-hand experience, Matthew O'Farrell knows all about ... can be treated. , A medically retired Army veteran, ... platoon sustained multiple attacks resulting in five casualties. After ... PTSD and honorably discharged from the Army. , “I ... myself from my friends and family,” recalled O’Farrell, who ...
(Date:9/23/2014)... HealthDay Reporter TUESDAY, Sept. 23, 2014 ... for providing better care, not more ... choices. A new report suggests that,s the direction ... the IMS Institute for Healthcare Informatics in Parsippany, N.J., identifies ... the delivery of health care and use of medicines over ...
(Date:9/23/2014)... What information do patients need to ... (NQF) released a report ( http://bit.ly/1DwekE9 ), consumer ... ( http://bit.ly/1tX3lzA ) resulting from an in-depth look ... define affordability, and what information and changes are ... healthcare at the lowest possible cost. ...
(Date:9/23/2014)... A recent Oregon survey about an exercise DVD that ... routine of elementary school students found it had a ... and offered clear advantages for overly sedentary educational programs. ... produced by the Healthy Youth Program of the Linus ... nationally. , Brain Breaks leads children in 5-7 minute ...
Breaking Medicine News(10 mins):Health News:Virtual Reality software to help treat PTSD 2Health News:Virtual Reality software to help treat PTSD 3Health News:Report Identifies Game Changers for U.S. Health Care 2Health News:Report Identifies Game Changers for U.S. Health Care 3Health News:Finding Affordable Care: Asking the Right Question is Key 2Health News:'Brain Breaks' increase activity, educational performance in elementary schools 2Health News:'Brain Breaks' increase activity, educational performance in elementary schools 3
... ... ... ... ...
... For some Canadians, any cut such as from dental ... Although they are not hemophiliacs, for some an ordinary bruise ... knees, elbows and ankles are crippled when bleeding seeps into ... required for recovery. Now a team led by ...
... recovery for people with disabilities following major natural disasters, ... in the International Journal of Emergency Management . ... other natural disasters, and even technological emergencies it has ... disaster and emergency preparedness for people with disabilities. Following ...
... will take place at the University of Haifa on Monday, ... sessions and dozens of lectures presenting studies that encompass the ... "This is a wide phenomenon that touches many audiences and ... and its various disciplines have found it worthy of attention ...
... ... ... -- As Maryland Gov. Martin O’Malley proposes cutting $123 million from Medicaid for the 2011 ... by Dr. Todd Eberly, assistant professor of political science and coordinator of public policy studies ...
... may benefit those with aura, researchers say , THURSDAY, March ... magnetic pulse to the head may offer relief for some ... migraine sufferers who experience "aura," expand on previous research by ... only at the doctor,s office. , It,s unclear, however, how ...
Cached Medicine News:Health News:Hard to Treat Diseases (HTDS) Collagenna Skin Care Business Model and Chilean Update 2Health News:Hard to Treat Diseases (HTDS) Collagenna Skin Care Business Model and Chilean Update 3Health News:Hard to Treat Diseases (HTDS) Collagenna Skin Care Business Model and Chilean Update 4Health News:Hard to Treat Diseases (HTDS) Collagenna Skin Care Business Model and Chilean Update 5Health News:Hard to Treat Diseases (HTDS) Collagenna Skin Care Business Model and Chilean Update 6Health News:Hard to Treat Diseases (HTDS) Collagenna Skin Care Business Model and Chilean Update 7Health News:Hard to Treat Diseases (HTDS) Collagenna Skin Care Business Model and Chilean Update 8Health News:Hard to Treat Diseases (HTDS) Collagenna Skin Care Business Model and Chilean Update 9Health News:Hard to Treat Diseases (HTDS) Collagenna Skin Care Business Model and Chilean Update 10Health News:Genetic cause discovered for rare bleeding disorder 2Health News:Emergency online communities 2Health News:Proposed Medicaid Cuts Threatens Health Care Access for 400,000 Maryland Children 2Health News:Proposed Medicaid Cuts Threatens Health Care Access for 400,000 Maryland Children 3Health News:New Hope for Migraine Patients 2
(Date:9/23/2014)... Heart Valve 2007 to 2020 - Europe ( ... UK, Spain ) Summary GBI Research,s report, "Market ... ( Germany , France , Italy ... transcatheter heart valves market in Europe . The analysis includes ... company share data by revenue in 2013 for the following countries: ...
(Date:9/23/2014)... , Sept. 23, 2014  SI-BONE, Inc., a ... iFuse Implant System, ® a minimally invasive surgical ... joint, today announced that the U.S. Patent and Trademark ... systems and methods for the fixation and fusion of ... fenestrated implant with a tapered distal end that may be placed from ...
(Date:9/23/2014)... 2014  Global Discovery Biosciences, a laboratory dedicated to ... biggest healthcare challenges, announces their collaboration with IPMD, Inc. ... for the early detection of lung cancer. ... Typically, the symptoms and subsequent diagnosis of lung cancer ... chance of a cure has already passed. Early screening ...
Breaking Medicine Technology:Market Snapshot: Transcatheter Heart Valve 2007 to 2020 - Europe (Germany, France, Italy, UK, Spain) 2SI-BONE, Inc. Strengthens Patent Portfolio with the U.S. Patent and Trademark Office's Issuance of Threaded, Fenestrated Implant Method Patent 2SI-BONE, Inc. Strengthens Patent Portfolio with the U.S. Patent and Trademark Office's Issuance of Threaded, Fenestrated Implant Method Patent 3Global Discovery Biosciences Announces Collaboration with IPMD, Inc. to Develop Innovative Aptamer-Based Blood Test for the Early Detection of Lung Cancer 2
... , May 6 Intercell AG (VSE: ICLL) today announced ... Cytos, platform technology for monoclonal antibody discovery. The technology is based on ... of anti-infective antibodies to prevent and treat infectious diseases. , ... Under the agreed terms Intercell will pay ...
... MILWAUKEE , May 5 Children,s Hospital of ... one of two in a pediatric hospital in the nation. ... the top-rated pediatric hospitals in the country. The Variety Orthopedic ... aid in treating children with scoliosis and other chronic orthopedic ...
Cached Medicine Technology:Intercell Acquires Antibody Technology Platform to Further Exploit Its Capabilities to Combat Infectious Diseases 2Children's Hospital of Wisconsin One of Two Pediatric Hospitals in Nation to Implement EOS Scanner 2Children's Hospital of Wisconsin One of Two Pediatric Hospitals in Nation to Implement EOS Scanner 3Children's Hospital of Wisconsin One of Two Pediatric Hospitals in Nation to Implement EOS Scanner 4
Solid steel construction for lifelong quality. Strong, smooth and quiet electro-mechanical up/down movement. Dual castor, locking wheels for use on carpet or tile flooring. Easy cleaning, deluxe lami...
Trial lens set +/- Cyl....
... Contemporary Soft Touch control panel with ... Pebble Gray, Noir Black, Colonial Blue and ... arms. Durable cast iron and steel construction ... smooth, quiet and reliable up/down chair movement. ...
Our Ophthalmic Diagnostic Sets offer everything an eye care specialist needs. Complete your set with your choice of ophthalmoscope, retinoscope, handle, and case....
Medicine Products: