Navigation Links
Optimal systemic and splanchnic hemodynamic state after living-donor liver transplantation
Date:11/13/2007

Almost all adult recipients who undergo LDLT develop liver cirrhosis with long-term portal hypertension. Portal hypertension results in vascular dilatation and collateral pathways. Thus, various alterations in systemic hemodynamics and splanchnic circulation occur, and adult recipients often present characteristic hemodynamics before LDLT. A research group from Kyoto University Hospital, Japan (Hori T, Yagi S, Iida T, Uemoto S), non-invasively investigated systemic hemodynamics and splanchnic circulation after LDLT in 30 adult recipients with liver cirrhosis who underwent LDLT (2003-2006), and their research has been published on the November issue 28 of World Journal of Gastroenterology. The article ascertained the correlation between systemic hemodynamics and splanchnic circulation, and clarified how systemic hemodynamic state impacts on local graft circulation. Interestingly, the results of splanchnic circulatory parameters in their current study reveal systemic hemodynamics correlate well with splanchnic circulation, and that subtle disorders of optimal systemic hyperdynamic state easily influence portal venous flow rather than hepatic arterial flow. Moreover, they also identify what hemodynamic state is necessary for excellent clinical outcomes corresponding to good graft functions. Dr. Hori demonstrated the persistence of characteristic systemic hyperdynamic state is indispensable for cirrhotic recipients, even after LDLT, by using a device that can non-invasively analyze the kinetics of indocyanine green, and he is doing further study now at Kyoto University Hospital. Since portal venous flow has been shown to have a large influence on liver regeneration after LDLT, successful clinical outcomes in cirrhotic LDLT recipients are attributed to optimal stability of systemic hyperdynamic state yielding sufficient portal venous flow.


'/>"/>

Contact: You-De Chang
y.d.chang@wjgnet.com
86-108-538-1892
World Journal of Gastroenterology
Source:Eurekalert

Page: 1

Related medicine news :

1. U of M performs first systemic therapy for fatal childhood disease
2. Millennium Announces MLN1202 Significantly Reduced Marker of Systemic Inflammation and Identifies Genomic Biomarker For Responders
3. Looking at Glaucoma as a Systemic Disease
4. Conventional prognostic factors fail to explain better prostate cancer survival in most Asian men
5. First biomarker discovered that predicts prostate cancer outcome
6. Frequent Prostate Screens Fail to Improve Aggressive Cancer Diagnoses
7. New male sling procedure helps prostate cancer survivors who suffer from urinary incontinence
8. Us TOO Launches National SEA Blue Campaign for Prostate Cancer Awareness Month
9. HHS Announces $75 Million in Supplemental Funding to States for Pandemic Flu Preparedness
10. 4-Star Gen. Barry Mccaffrey, Former U.S. Drug Czar, to Keynote Recovery Happens! Rally for Treatment: Wed., Sept. 5, 11 Am, State Capitol West Steps, Sacramento
11. Expert on Emerging Infectious Zoonotic Diseases Joining K-State as a Regents Distinguished Professor
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... Fort Worth, TX (PRWEB) , ... October 13, ... ... and financial planning agency serving communities in the greater Dallas, Miami, and Raleigh ... a young boy fighting to overcome a rare and deadly chromosome abnormality. , ...
(Date:10/13/2017)... ... October 13, 2017 , ... The American Board of ... its next President and Chief Executive Officer, succeeding Dr. James C. Puffer upon his ... July 1, 2018 until Dr. Puffer’s retirement at the end of 2018. Upon assuming ...
(Date:10/13/2017)... ... October 13, 2017 , ... Lori R. Somekh, founder ... of ElderCounsel, a national organization of elder law and special needs planning attorneys. “Membership ... rules. It also provides a forum to network with elder law attorneys nationwide,” said ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network for ... for action towards gender equality at their inaugural Summit in New York City in ... reached a social audience of over 3 million. To watch the Mobilize Women video, ...
(Date:10/13/2017)... ... 2017 , ... Coveros, a leader in agile coaching services ... by the Center for Medicare and Medicaid Services (CMS). The Enterprise Agile Transformation ... Agile methodologies in a consistent and high value manner across CMS programs. Coveros ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... PHILADELPHIA , Oct. 2, 2017 Halo Labs announces ... particle analysis system called the HORIZON at MIBio 2017 in ... analyzes subvisible and visible particulate matter in biopharmaceutical samples with unprecedented ... use of the novel technique Backgrounded Membrane Imaging. ... The HORIZON subvisible particle analysis system ...
(Date:9/28/2017)... WASHINGTON , Sept. 28, 2017 Cohen ... to advance the use of wearable and home sensors ... brain disorders. Early Signal Foundation, a nonprofit organization focused ... populations, will provide an affordable analytical system to record ... ...
(Date:9/25/2017)... AMSTERDAM , Sept. 25, 2017   ... Trial Master File solutions, today—from the IQPC Trial ... Amsterdam , NL)—announced that EastHORN Clinical Services ... its clinical programs and TMF management. EastHORN, a ... Montrium,s eTMF platform to increase transparency to enable ...
Breaking Medicine Technology: