Navigation Links
Optimal systemic and splanchnic hemodynamic state after living-donor liver transplantation
Date:11/13/2007

Almost all adult recipients who undergo LDLT develop liver cirrhosis with long-term portal hypertension. Portal hypertension results in vascular dilatation and collateral pathways. Thus, various alterations in systemic hemodynamics and splanchnic circulation occur, and adult recipients often present characteristic hemodynamics before LDLT. A research group from Kyoto University Hospital, Japan (Hori T, Yagi S, Iida T, Uemoto S), non-invasively investigated systemic hemodynamics and splanchnic circulation after LDLT in 30 adult recipients with liver cirrhosis who underwent LDLT (2003-2006), and their research has been published on the November issue 28 of World Journal of Gastroenterology. The article ascertained the correlation between systemic hemodynamics and splanchnic circulation, and clarified how systemic hemodynamic state impacts on local graft circulation. Interestingly, the results of splanchnic circulatory parameters in their current study reveal systemic hemodynamics correlate well with splanchnic circulation, and that subtle disorders of optimal systemic hyperdynamic state easily influence portal venous flow rather than hepatic arterial flow. Moreover, they also identify what hemodynamic state is necessary for excellent clinical outcomes corresponding to good graft functions. Dr. Hori demonstrated the persistence of characteristic systemic hyperdynamic state is indispensable for cirrhotic recipients, even after LDLT, by using a device that can non-invasively analyze the kinetics of indocyanine green, and he is doing further study now at Kyoto University Hospital. Since portal venous flow has been shown to have a large influence on liver regeneration after LDLT, successful clinical outcomes in cirrhotic LDLT recipients are attributed to optimal stability of systemic hyperdynamic state yielding sufficient portal venous flow.


'/>"/>

Contact: You-De Chang
y.d.chang@wjgnet.com
86-108-538-1892
World Journal of Gastroenterology
Source:Eurekalert

Page: 1

Related medicine news :

1. U of M performs first systemic therapy for fatal childhood disease
2. Millennium Announces MLN1202 Significantly Reduced Marker of Systemic Inflammation and Identifies Genomic Biomarker For Responders
3. Looking at Glaucoma as a Systemic Disease
4. Conventional prognostic factors fail to explain better prostate cancer survival in most Asian men
5. First biomarker discovered that predicts prostate cancer outcome
6. Frequent Prostate Screens Fail to Improve Aggressive Cancer Diagnoses
7. New male sling procedure helps prostate cancer survivors who suffer from urinary incontinence
8. Us TOO Launches National SEA Blue Campaign for Prostate Cancer Awareness Month
9. HHS Announces $75 Million in Supplemental Funding to States for Pandemic Flu Preparedness
10. 4-Star Gen. Barry Mccaffrey, Former U.S. Drug Czar, to Keynote Recovery Happens! Rally for Treatment: Wed., Sept. 5, 11 Am, State Capitol West Steps, Sacramento
11. Expert on Emerging Infectious Zoonotic Diseases Joining K-State as a Regents Distinguished Professor
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/24/2017)... ... January 24, 2017 , ... Bellus Medical, a leader in medical aesthetics, ... In his new role Dr. Dobke will provide physician oversight for in-house clinical studies ... Head of Plastic Surgery and Associate Professor of Surgery at UC San Diego Health ...
(Date:1/24/2017)... ... January 24, 2017 , ... Providing solutions to critical economic ... the Frank Hawkins Kenan Institute of Private Enterprise at the University ... makers identified concrete solutions at the “What’s Next, America?” conference at the Kenan ...
(Date:1/24/2017)... Rosa, CA (PRWEB) , ... January 24, 2017 , ... ... is good news for everyone and particularly good news for prostate cancer patients: incidents ... the diagnosis. , According to the report the cancer death rate has dropped from ...
(Date:1/24/2017)... ... ... American Family Care (AFC) has opened a new 4,000+ square foot state-of-the-art urgent ... area. The Bedford clinic will be the nineteenth location opened by AFC in Massachusetts ... Dr. Kristina Orio. Adams and Orio also independently own and operate AFC clinics in ...
(Date:1/24/2017)... ... January 24, 2017 , ... TopConsumerReviews.com recently ... relieving premenstrual syndrome, or PMS . , Most women of child-bearing age ... include cramps, constipation, irritability, headaches, fatigue, and other discomfort. For some women, ...
Breaking Medicine News(10 mins):
(Date:1/24/2017)... 24, 2017   QR Pharma , Inc., ... novel therapies for the treatment of Alzheimer,s, Parkinson,s ... of four world-class key opinion leaders to its ... QR Pharma,s previous roster of impressive advisors in ... support the development of the breakthrough mechanism of ...
(Date:1/24/2017)... , January 24, 2017 The global  active ... 239.8 billion by 2025, based on a new report by Grand View ... is projected to drive the market over the forecast period. Advancements in ... also estimated to boost growth.  Continue Reading ... ...
(Date:1/24/2017)... 2017 INTRODUCTION Injectable drug delivery systems ... with vials to prefilled syringes, auto-injectors, pen injectors ... become preferred devices for parenteral administration of drugs. ... rising strongly over the past several years. A ... this format for delivering drugs. The popularity of ...
Breaking Medicine Technology: